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1. 发明申请

WO2007070727A1 TECHNIQUES FOR SENSING AND ADJUSTING A COMPLIANCE VOLTAGE IN AN IMPLANTABLE STIMULATOR DEVICE 审中-公开
标题翻译：用于感应和调节可植入刺激装置中的合格电压的技术
公开(公告)号：WO2007070727A1
公开(公告)日：2007-06-21
申请号：PCT/US2006/060085
申请日：2006-10-19
申请人： ADVANCED BIONICS CORPORATION , SHI, Jess, W. , HE, Yuping , DOAN, Que , PETERSON, David, K.l.
发明人： SHI, Jess, W. , HE, Yuping , DOAN, Que , PETERSON, David, K.l.
IPC分类号： A61N1/08 , A61N1/36 , A61N1/378
CPC分类号： A61N1/36125 , A61N1/36071 , A61N1/37
摘要： Disclosed herein are methods and circuitry for monitoring and adjusting a compliance voltage in an implantable stimulator devices to an optimal value that is sufficiently high to allow for proper circuit performance (i.e., sufficient current output), but low enough that power is not needlessly wasted via excessive voltage drops across the current output circuitry. The algorithm measures output voltages across the current source and sink circuitry during at least periods of actual stimulation when both the current sources and sinks arc operable, and adjusts the compliance voltage so as to reduce these output voltages to within guard band values preferably indicative for operation in transistor saturation. The output voltages can additionally be monitored during periods between stimulation pulses to improve the accuracy of the measurement, and is further beneficial in that such additional measurements are not perceptible to the patient.
摘要翻译：本文公开了用于监测和调整可植入式刺激器装置中的顺应性电压的方法和电路，以达到足够高以允许适当的电路性能（即，足够的电流输出）的最佳值，但是足够低以使得功率不会被无用地浪费通过电流输出电路上的电压过大。当电流源和吸收点两者可操作时，该算法在至少实际刺激期间测量电流源和接收电路两端的输出电压，并调整顺从电压，以便将这些输出电压降低到优选指示操作的保护带值内晶体管饱和。在刺激脉冲之间的周期期间可以另外监视输出电压，以提高测量的准确度，并且进一步有益的是，这种附加测量对于患者是不可察觉的。

2. 发明申请

WO2008048725A1 CURRENT GENERATION ARCHITECTURE FOR AN IMPLANTABLE STIMULATOR DEVICE HAVING COARSE AND FINE CURRENT CONTROL 审中-公开
标题翻译：具有粗糙和精细电流控制的可植入刺激装置的电流生成结构
公开(公告)号：WO2008048725A1
公开(公告)日：2008-04-24
申请号：PCT/US2007/072238
申请日：2007-06-27
申请人： ADVANCED BIONICS CORPORATION , PARRAMON, Jordi , PETERSON, David, K.l. , GRIFFITH, Paul, J.
发明人： PARRAMON, Jordi , PETERSON, David, K.l. , GRIFFITH, Paul, J.
IPC分类号： A61N1/36 , H02M3/07
CPC分类号： A61N1/36125 , A61N1/0531 , A61N1/0534 , A61N1/0541 , A61N1/0543 , A61N1/0551 , A61N1/36071
摘要： Disclosed herein is a current generation architecture for an implantable stimulator device such as an Implantable Pulse Generator (IPG). Current source and sink circuitry are both divided into coarse and fine portions, which respectively can provide a coarse and fine current resolution to a specified electrode on the IPG. The coarse portion is distributed across all of the electrodes and so can source or sink current to any of the electrodes. The coarse portion is divided into a plurality of stages, each of which is capable via an associated switch bank of sourcing or sinking a coarse amount of current to or from any one of the electrodes on the device. The fine portion of the current generation circuit preferably includes source and sink circuitry dedicated to each of the electrode on the device, which can comprise digital-to-analog current converters (DACs). The DACs also receives the above-noted reference current, which is amplified by the DACs in fine increments by appropriate selection of fine current control signals. When the coarse and fine current control circuitry are used in tandem, ample current with a fine current resolution can be achieved at any electrode and in a space- and power-efficient manner.
摘要翻译：本文公开了用于植入式脉冲发生器（IPG）的植入式刺激器装置的当前一代架构。电流源和接收电路都分为粗细部分，分别可以为IPG上的指定电极提供粗细和精细的电流分辨率。粗糙部分分布在所有电极上，因此可以将电流吸收或吸收到任何电极。粗略部分被分成多个级，每个级能够经由相关联的开关组，该器件对器件中的任何一个电极产生或吸收粗略的电流。电流产生电路的优良部分优选地包括专用于器件上的每个电极的源极和漏极电路，其可以包括数模转换器（DAC）。 DAC还接收上述参考电流，其通过适当选择精细电流控制信号以细微增量由DAC放大。当粗调和精细电流控制电路串联使用时，可以在任何电极上以空间和功率有效的方式实现具有精细电流分辨率的充足电流。

3. 发明申请

WO2010006304A2 SYSTEM AND METHOD FOR CONVERTING TISSUE STIMULATION PROGRAMS IN A FORMAT USABLE BY AN ELECTRICAL CURRENT STEERING NAVIGATOR 审中-公开
标题翻译：用于电流转向导管可用的格式转换组织刺激方案的系统和方法
公开(公告)号：WO2010006304A2
公开(公告)日：2010-01-14
申请号：PCT/US2009/050309
申请日：2009-07-10
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION , THACKER, James, R. , MOFFITT, Michael , BRADLEY, Kerry , PETERSON, David, K.l.
发明人： THACKER, James, R. , MOFFITT, Michael , BRADLEY, Kerry , PETERSON, David, K.l.
IPC分类号： A61N1/08 , A61N1/34
CPC分类号： A61N1/37264 , A61N1/36071 , A61N1/36146 , A61N1/3615 , A61N1/36167 , A61N1/36185 , A61N1/37247 , G06F19/00 , G16H40/63
摘要： A method, computer medium, and system for programming a controller is provided. The controller controls electrical stimulation energy output to electrodes, and stores a set of programmed stimulation parameters associated with the electrodes. The programmed stimulation parameter set is compared with sets of reference stimulation parameters, each of the reference sets of stimulation parameters being associated with the electrodes. If an identical match is determined between the programmed stimulation parameter set and any one of the reference stimulation parameter sets exists based on the comparison, the identically matched stimulation parameter set is selected as an initial stimulation parameter set. If an identical match does not exist, a best between the programmed stimulation parameter set and the reference stimulation parameter sets is determined and selected as the initial stimulation parameter set. The controller is then programmed with a new set of programmable stimulation parameters based on the initial stimulation parameter set.
摘要翻译：提供了一种用于编程控制器的方法，计算机介质和系统。控制器控制对电极的电刺激能量输出，并且存储与电极相关联的一组编程的刺激参数。将编程的刺激参数集与参考刺激参数的集合进行比较，每个参考组的刺激参数与电极相关联。如果在编程的刺激参数集之间确定相同的匹配，并且基于比较存在参考刺激参数集中的任一个，则选择相同匹配的刺激参数集作为初始刺激参数集。如果不存在相同的匹配，则确定编程的刺激参数集和参考刺激参数集之间的最佳值，并将其选为初始刺激参数集。然后基于初始刺激参数集，控制器用一组新的可编程刺激参数进行编程。

4. 发明申请

WO2010011721A1 SYSTEM AND METHOD FOR MAINTAINING A DISTRIBUTION OF CURRENTS IN AN ELECTRODE ARRAY USING INDEPENDENT VOLTAGE SOURCES 审中-公开
标题翻译：使用独立电压源在电极阵列中维持电流分配的系统和方法
公开(公告)号：WO2010011721A1
公开(公告)日：2010-01-28
申请号：PCT/US2009/051361
申请日：2009-07-22
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION , MOFFITT, Michael, A. , PETERSON, David, K.l.
发明人： MOFFITT, Michael, A. , PETERSON, David, K.l.
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/36071 , A61N1/0551
摘要： In one technique, a desired electrical current distribution on at least three active electrodes is selected. An electrical energy perturbation is generated on at least one electrode. A current-to-voltage relationship at each active electrode is estimated based on the energy perturbation. The current-to-voltage relationship for each active electrode takes into account current flow through other active electrodes. The voltage distribution necessary to achieve the desired current distribution is determined based on the estimated current-to-voltage relationship. Voltage-regulated energy is conveyed between the electrodes and tissue in accordance with the determined electrical voltage distribution. In another technique, electrical energy perturbation on at least one of the electrodes is generated. Network resistances for each of at least three active electrodes are computed in response to the energy perturbation. The network resistances represent the resistances between the electrodes and common node to which the electrodes are connected.
摘要翻译：在一种技术中，选择在至少三个有效电极上的期望的电流分布。在至少一个电极上产生电能扰动。基于能量扰动来估计每个有源电极处的电流 - 电压关系。每个有源电极的电流 - 电压关系考虑到通过其他有源电极的电流。基于估计的电流 - 电压关系确定实现所需电流分布所需的电压分布。电压调节能量根据确定的电压分布在电极和组织之间传送。在另一种技术中，产生至少一个电极上的电能扰动。响应于能量扰动计算至少三个有效电极中的每一个的网络电阻。网络电阻表示电极与电极连接的公共节点之间的电阻。

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