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1. 发明申请

WO2012054268A3 MULTIFUNCTIONAL MEDICAL DEVICE FOR TELEMEDICINE APPLICATIONS 审中-公开
标题翻译：用于远程应用的多功能医疗设备
公开(公告)号：WO2012054268A3
公开(公告)日：2012-07-12
申请号：PCT/US2011055867
申请日：2011-10-12
申请人： 3M INNOVATIVE PROPERTIES CO , BEDINGHAM WILLIAM , SCHMIDT THOMAS P , GONZALEZ BERNARD A , KRUEGER SHAUN M
发明人： BEDINGHAM WILLIAM , SCHMIDT THOMAS P , GONZALEZ BERNARD A , KRUEGER SHAUN M
IPC分类号： G06Q50/00 , A61B5/00
CPC分类号： A61B5/0024 , A61B5/002 , A61B5/0022 , A61B2560/0443 , A61B2562/226 , G06F19/3418 , G06Q50/22
摘要： A multifunction medical device includes a housing configured for hand-held manipulation, a processing unit within the housing, and a connector on the outer surface of the housing. The connector is coupled to the processing unit and operable to connect to a plurality of different types of medical sensors. The processing unit is configured to determine a type of a medical sensor coupled to the connector.
摘要翻译：多功能医疗装置包括构造成用于手持操作的壳体，壳体内的处理单元以及壳体外表面上的连接器。连接器耦合到处理单元并且可操作以连接到多种不同类型的医疗传感器。处理单元被配置为确定耦合到连接器的医疗传感器的类型。

2. 发明申请

WO2009134823A3 STRETCHABLE CONDUCTIVE CONNECTOR 审中-公开
标题翻译：可伸缩导电连接器
公开(公告)号：WO2009134823A3
公开(公告)日：2010-03-04
申请号：PCT/US2009042010
申请日：2009-04-29
申请人： 3M INNOVATIVE PROPERTIES CO , OSTER CRAIG D , CARIM HATIM M , MENON VINOD P , BEDINGHAM WILLIAM
发明人： OSTER CRAIG D , CARIM HATIM M , MENON VINOD P , BEDINGHAM WILLIAM
IPC分类号： H01R13/24
CPC分类号： H01R13/2421 , H01R13/2414 , H01R13/33 , Y10T29/49117
摘要： A stretchable conductive connector. The conductive connector can include a viscoelastic support member having a variable length, and a conductor coupled to the support member. The conductor can include at least one bend to accommodate the variable length of the viscoelastic support member.
摘要翻译：可伸缩导电连接器。导电连接器可以包括具有可变长度的粘弹性支撑构件和连接到支撑构件的导体。导体可以包括至少一个弯曲部以适应粘弹性支撑构件的可变长度。

3. 发明申请

WO2008134470A3 METHODS FOR NUCLEIC ACID AMPLIFICATION 审中-公开
标题翻译：核酸扩增方法
公开(公告)号：WO2008134470A3
公开(公告)日：2009-03-12
申请号：PCT/US2008061495
申请日：2008-04-25
申请人： 3M INNOVATIVE PROPERTIES CO , PARTHASARATHY RANJANI V , LIU HSI-CHOU , XIA WENSHENG , BENNAARS-EIDEN ASUMPTA , HOLT PAUL N , BEDINGHAM WILLIAM , KOKAISEL CHRISTOPHER R , PEDERSON JEFFREY C
发明人： PARTHASARATHY RANJANI V , LIU HSI-CHOU , XIA WENSHENG , BENNAARS-EIDEN ASUMPTA , HOLT PAUL N , BEDINGHAM WILLIAM , KOKAISEL CHRISTOPHER R , PEDERSON JEFFREY C
IPC分类号： C12N15/10
CPC分类号： B01L3/502753 , B01L7/52 , B01L2200/0647 , B01L2300/0806 , B01L2400/0677 , C12Q1/6806 , C12Q1/6846 , C12Q2563/149 , C12Q2563/137
摘要： The present invention provides methods for amplifying nucleic acid after isolating nucleic acid from a sample using functionalized support material.
摘要翻译：本发明提供了使用官能化载体材料从样品中分离核酸后扩增核酸的方法。

4. 发明申请

WO2005061709A3 VARIABLE VALVE APPARATUS AND METHODS 审中-公开
标题翻译：可变气门装置和方法
公开(公告)号：WO2005061709A3
公开(公告)日：2005-07-28
申请号：PCT/US2004038924
申请日：2004-11-18
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： BEDINGHAM WILLIAM , ROBOLE BARRY W , PARTHASARATHY RANJANI V , ERICSON KATYA
IPC分类号： B01L3/00 , C12M1/34 , C12N15/10 , C12Q1/68 , G01N30/00
CPC分类号： B01L3/502738 , B01L2300/0806 , B01L2400/0409 , B01L2400/0677
摘要： Sample processing devices with variable valve structures and methods of using the same are disclosed. The valve structures allow for removal of selected portions of the sample material located within the process chamber. Removal of the selected portions is achieved by forming an opening in a valve septum at a desired location. The valve septums may be large enough to allow for adjustment of the location of the opening based on the characteristics of the sample material in the process chamber. If the sample processing device is rotated after the opening is formed, the selected portion of the material located closer to the axis of rotation exits the process chamber through the opening. The remainder of the sample material cannot exit through the opening because it is located farther from the axis of rotation than the opening.
摘要翻译：公开了具有可变阀门结构的样品处理装置及其使用方法。阀结构允许去除位于处理室内的样品材料的选定部分。通过在期望位置处的阀隔膜中形成开口来实现选定部分的去除。阀隔膜可以足够大以允许基于处理室中的样品材料的特性来调节开口的位置。如果样品处理装置在开口形成之后旋转，则位于更靠近旋转轴线的材料的所选部分通过开口离开处理室。样品材料的其余部分不能通过开口排出，因为它位于比开口更远离旋转轴的位置。

5. 发明申请

WO2007005853A3 COMPLIANT MICROFLUIDIC SAMPLE PROCESSING DISKS 审中-公开
标题翻译：合适的微流体样品加工盘
公开(公告)号：WO2007005853A3
公开(公告)日：2007-03-22
申请号：PCT/US2006026016
申请日：2006-06-30
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： BEDINGHAM WILLIAM , ROBOLE BARRY W
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/502738 , B01L7/52 , B01L2200/027 , B01L2200/0689 , B01L2300/044 , B01L2300/0803 , B01L2300/0887 , B01L2300/1805
摘要： Microfluidic sample processing disks with a plurality of fluid structures formed therein are disclosed. Each of the fluid structures preferably includes an input well (20) and one or more process chambers (30) connected to the input well (20) by one or more delivery channels (42, 44, 46). The process chambers (30) may be arranged in a compliant annular processing ring that is adapted to conform to the shape of an underlying thermal transfer surface under pressure. That compliance may be delivered in the disks of the present invention by locating the process chambers in an annular processing ring in which a majority of the volume is occupied by the process chambers. Compliance within the annular processing ring may alternatively be provided by a composite structure within the annular processing ring that includes covers attached to a body using pressure sensitive adhesive.
摘要翻译：公开了具有形成在其中的多个流体结构的微流体样品处理盘。每个流体结构优选地包括输入井（20）和通过一个或多个输送通道（42,44,46）连接到输入井（20）的一个或多个处理室（30）。处理室（30）可以布置成柔顺的环形加工环，其适于在压力下符合下面的热转印表面的形状。通过将处理室定位在其中大部分体积被处理室占据的环形处理环中，可以在本发明的盘中传送顺从性。环形加工环内的合规性可替代地由环形加工环内的复合结构提供，其包括使用压敏粘合剂附接到主体的盖。

6. 发明申请

WO2005068628A3 METHODS FOR NUCLEIC ACID ISOLATION AND KITS USING SOLID PHASE MATERIAL 审中-公开
标题翻译：使用固体相材料的核酸分离方法和试剂盒
公开(公告)号：WO2005068628A3
公开(公告)日：2005-09-15
申请号：PCT/US2004035367
申请日：2004-10-25
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： PARTHASARATHY RANJANI V , ERICSON KATYA K , BEDINGHAM WILLIAM
IPC分类号： C12N15/10 , B01L3/00 , C07H21/00 , C12M1/12 , C12Q1/68 , G01N30/30
CPC分类号： C12N15/10
摘要： The present invention provides methods and kits for isolating nucleic acid from a sample, preferably from a biological sample, using a microfluidic device and sedimenting reagent.
摘要翻译：本发明提供了使用微流体装置和沉降试剂从样品中分离核酸，优选来自生物样品的方法和试剂盒。

7. 发明申请

WO2007005854A3 MODULAR SAMPLE PROCESSING APPARATUS KITS AND MODULES 审中-公开
标题翻译：模块化样品加工装置和模块
公开(公告)号：WO2007005854A3
公开(公告)日：2007-03-15
申请号：PCT/US2006026017
申请日：2006-06-30
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： BEDINGHAM WILLIAM , ROBOLE BARRY W
IPC分类号： G01N35/02
CPC分类号： G01N35/025
摘要： Modular sample processing apparatus kits that can provide a user with the flexibility to customize a disk-based assay in view of a variety of factors are disclosed. The sample processing apparatus kits of the present invention include one or more process modules that can be retained within openings in a frame. The frame and process modules of the sample processing apparatus kits are preferably adapted for use in sample processing systems that compress the apparatus. The process modules may contain different reagents to perform different tests on the same sample materials or a variety of sample materials. As a result, a single sample processing apparatus can be used to perform a variety of different tests and may include a quality control module capable of providing feedback to the user as to the accuracy of the processes run using the sample processing apparatus. Methods of using the sample processing apparatus that include deforming the process modules and frame are also disclosed.
摘要翻译：公开了可以根据各种因素为用户提供定制基于磁盘的测定的灵活性的模块化样品处理装置套件。本发明的样品处理装置试剂盒包括可以保持在框架中的开口内的一个或多个处理模块。样品处理装置套件的框架和处理模块优选地适用于压缩装置的样品处理系统。过程模块可以包含不同的试剂以对相同的样品材料或各种样品材料进行不同的测试。结果，可以使用单个样本处理装置来执行各种不同的测试，并且可以包括质量控制模块，其能够向用户提供关于使用样本处理装置运行的处理的准确性的反馈。还公开了使用包括使处理模块和框架变形的样品处理装置的方法。

8. 发明申请

WO0239125A3 SAMPLE PROCESSING APPARATUS, METHODS AND SYSTEMS 审中-公开
标题翻译：样品加工设备，方法和系统
公开(公告)号：WO0239125A3
公开(公告)日：2003-03-27
申请号：PCT/US0129253
申请日：2001-09-18
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： BEDINGHAM WILLIAM , ROBOLE BARRY W , AYSTA JAMES
IPC分类号： B01L99/00 , G01N21/07 , G01N35/02 , G01N35/04 , G01N35/10 , B01L11/00 , B04B5/04
CPC分类号： G01N35/028 , B01L3/0293 , G01N21/07 , G01N35/10 , Y10T436/11 , Y10T436/111666 , Y10T436/25 , Y10T436/25375
摘要： Apparatus, methods, and systems for processing sample materials that may be presented in a standard microtiter plate are disclosed. The present invention provides a bridge between the standard microtiter plate systems, methods, protocols, etc. with their stationary wells and rotating sample processing devices that allow users to obtain the rapid processing advantages of the newer sample processing devices while retaining the benefits of the standard microtiter plate formats.
摘要翻译：公开了用于处理可能呈现在标准微量滴定板中的样品材料的装置，方法和系统。本发明提供了标准微量滴定板系统，方法，方案等与其固定井和旋转样品处理装置之间的桥梁，其允许用户获得较新样品处理装置的快速处理优点，同时保留标准的益处微量滴定板格式。

9. 发明申请

WO0246354A2 AUTOMATED IMAGING AND HARVESTING OF COLONIES OF THIN FILM CULTURE DEVICES 审中-公开
标题翻译：薄膜文化装置的自动成像和收集
公开(公告)号：WO0246354A2
公开(公告)日：2002-06-13
申请号：PCT/US0143880
申请日：2001-11-05
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： BEDINGHAM WILLIAM , RAJAGOPAL RAJ , WILLIAMS MICHAEL G
IPC分类号： C12M1/26 , C12M1/16 , C12N1/02
CPC分类号： C12M23/22 , C12M23/04 , C12M23/50 , C12M25/02 , C12M33/04
摘要： Thin film culture devices are described that have positioning structures, as well as methods for harvesting cells from colonies on the culture device based on location of colonies on the device relative to the positioning structures. In addition, a computer readable medium encoded with a computer program is described that identifies position of colonies relative to the positioning structures.
摘要翻译：描述了具有定位结构的薄膜培养装置，以及基于相对于定位结构在装置上的集落位置从培养装置上的菌落收集细胞的方法。此外，描述了用计算机程序编码的计算机可读介质，其识别殖民地相对于定位结构的位置。

10. 发明申请

WO2007005810A2 SAMPLE PROCESSING DEVICE COMPRESSION SYSTEMS AND METHODS 审中-公开
标题翻译：样品加工装置压缩系统和方法
公开(公告)号：WO2007005810A2
公开(公告)日：2007-01-11
申请号：PCT/US2006025944
申请日：2006-06-30
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： AYSTA JAMES E , BEDINGHAM WILLIAM , ROBOLE BARRY W
IPC分类号： B01L9/00 , B01L3/00 , G01N35/00 , G01N35/02
CPC分类号： B01L9/52 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L2200/0689 , B01L2300/041 , B01L2300/0803 , B01L2300/1805 , B01L2300/1861 , G01N35/025 , G01N2035/00366 , Y10S435/809
摘要： Sample processing systems and methods of using those systems for processing sample materials located in sample processing devices are disclosed. The sample processing systems include a rotating base plate on which the sample processing devices are located during operation of the systems. The systems also include a cover and compression structure designed to force a sample processing device towards the base plate. The preferred result is that the sample processing device is forced into contact with a thermal structure on the base plate. The systems and methods of the present invention may include one or more of the following features to enhance thermal coupling between the thermal structure and the sample processing device: a shaped transfer surface, magnetic compression structure, and floating or resiliently mounted thermal structure. The methods may preferably involve deformation of a portion of a sample processing device to conform to a shaped transfer surface.
摘要翻译：公开了使用这些系统来处理位于样品处理装置中的样品材料的样品处理系统和方法。样品处理系统包括在系统操作期间样品处理装置位于其上的旋转底板。该系统还包括设计成迫使样品处理装置朝向底板的盖和压缩结构。优选的结果是，样品处理装置被迫与基板上的热结构接触。本发明的系统和方法可以包括以下特征中的一个或多个，以增强热结构和样品处理装置之间的热耦合：成形转印表面，磁性压缩结构以及浮动或弹性安装的热结构。该方法可以优选地包括样品处理装置的一部分的变形以符合成形的转印表面。

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