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1. 发明申请

WO2009135940A2 INTELLIGENT MONITORING OF AN ELECTRICAL UTILITY GRID 审中-公开
标题翻译：智能监测电力实用网格
公开(公告)号：WO2009135940A2
公开(公告)日：2009-11-12
申请号：PCT/EP2009055610
申请日：2009-05-08
申请人： IBM , IBM UK , TAFT JEFFREY DAVID , ZHU YAN
发明人： TAFT JEFFREY DAVID , ZHU YAN
IPC分类号： G01D4/00
CPC分类号： G01D4/004 , Y02B90/242 , Y02B90/245 , Y04S20/322 , Y04S20/40
摘要： A method of managing an electric utility grid includes geographically grouping a set of customer electric usage meters to create a set of fine sensors on a power grid. Each usage meter in the grouped set is capable of being remotely monitored, and each usage meter is at a different location along the power line. If a power anomaly is detected at the subset of meters, then power to the electric utility grid is adjusted to correct the anomaly.
摘要翻译：一种管理电力公用电网的方法包括在一组用户电力使用量度表上进行地理分组，以在电网上创建一组精细的传感器。分组组中的每个使用度量表能够被远程监控，并且每个使用度量表位于沿着电力线的不同位置。如果在米的子集上检测到电力异常，则调整到电力公用电网的电力以校正异常。

2. 发明申请

WO2009014910A3 N-AZACYCLIC SUBSTITUTED PYRROLE, PYRAZOLE, IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES AS AGONISTS OF THE RUP3 OR GPR119 RECEPTOR FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS 审中-公开
公开(公告)号：WO2009014910A3
公开(公告)日：2009-01-29
申请号：PCT/US2008/069714
申请日：2008-07-10
申请人： METABOLEX, INC. , MA, Jingyuan , RABBAT, Christopher J. , SONG, Jiangao , CHEN, Xin , NASHASHIBI, Imad , ZHAO, Zuchun , NOVACK, Aaron , SHI, Dong Fang , CHENG, Peng , ZHU, Yan , MURPHY, Alison
发明人： MA, Jingyuan , RABBAT, Christopher J. , SONG, Jiangao , CHEN, Xin , NASHASHIBI, Imad , ZHAO, Zuchun , NOVACK, Aaron , SHI, Dong Fang , CHENG, Peng , ZHU, Yan , MURPHY, Alison
IPC分类号： C07D401/14 , C07D401/04 , C07D413/14 , C07D417/14 , A61K31/4439 , A61K31/506 , A61K31/454 , A61P3/10
摘要： Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control.

3. 发明申请

WO2008083238A3 HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS 审中-公开
标题翻译：用于治疗糖尿病和代谢障碍的异位受体激动剂
公开(公告)号：WO2008083238A3
公开(公告)日：2008-09-04
申请号：PCT/US2007088978
申请日：2007-12-27
申请人： METABOLEX INC , CHEN XIN , CHENG PENG , CLEMENS L EDWARD , JOHNSON JEFFREY D , MA JINGYUAN , MURPHY ALISON , NASHASHIBI IMAD , RABBAT CHRISTOPHER J , SONG JIANGAO , WILSON MARIA E , ZHU YAN , ZHAO ZUCHUN
发明人： CHEN XIN , CHENG PENG , CLEMENS L EDWARD , JOHNSON JEFFREY D , MA JINGYUAN , MURPHY ALISON , NASHASHIBI IMAD , RABBAT CHRISTOPHER J , SONG JIANGAO , WILSON MARIA E , ZHU YAN , ZHAO ZUCHUN
IPC分类号： A01N43/40 , A61K31/445 , A61K31/497
CPC分类号： A61K31/506 , A61K31/454 , C07D277/42 , C07D401/04 , C07D401/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14
摘要： Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
摘要翻译：提供了化合物和方法用于治疗特别是II型糖尿病和与血糖控制不良相关的其它疾病。本发明的化合物是口服活性的。

4. 发明申请

WO2007038277A2 RESOLUTION OF ALPHA-(PHENOXY) PHENYLACETIC ACID DERIVATIVES WITH NAPHTHYL-ALKYLAMINES 审中-公开
标题翻译：具有萘甲酰胺的ALPHA-（苯氧基）苯甲酸衍生物的分解
公开(公告)号：WO2007038277A2
公开(公告)日：2007-04-05
申请号：PCT/US2006/036993
申请日：2006-09-21
申请人： METABOLEX, INC. , CHENG, Peng , MA, Jingyuan , CHEN, Xin , ZHU, Yan , ZHAO, Zuchun
发明人： CHENG, Peng , MA, Jingyuan , CHEN, Xin , ZHU, Yan , ZHAO, Zuchun
IPC分类号： C07C59/88
CPC分类号： C07C233/18 , C07B57/00 , C07C51/487 , C07C231/14 , C07C59/88
摘要： The present invention provides a methods and compounds for producing an enantiomerically enriched α-(phenoxy)phenylacetic acid compound of the formula: (I) from a mixture of its enantiomers, where R 1 is alkyl or haloalkyl and X is halide.
摘要翻译：本发明提供了一种方法和化合物，用于从其对映异构体的混合物制备对映异构体富集的式（I）的（（I）） - （苯氧基）苯乙酸化合物，其中R 1是烷基或卤代烷基， X是卤化物。

5. 发明申请

WO2006018669A1 METHODS AND APPARATUS FOR BALANCING MODULATION IN CELLULAR COMMUNICATIONS OVER NOISY CHANNELS 审中-公开
标题翻译：噪声通道中细胞通信平衡调制的方法与装置
公开(公告)号：WO2006018669A1
公开(公告)日：2006-02-23
申请号：PCT/IB2004/002674
申请日：2004-08-17
申请人： NOKIA CORPORATION , XU, Zhaoji , ZHAO, Zhu, Yan
发明人： XU, Zhaoji , ZHAO, Zhu, Yan
IPC分类号： H04L1/18
CPC分类号： H04L1/1819 , H04L1/0003 , H04L1/0006 , H04L1/0013 , H04L1/0068 , H04L1/0071 , H04L1/1893 , H04L5/143 , H04L27/183 , H04L27/2075
摘要： Methods and apparatus for balancing multi-symbol modulation schemes in cellular communications are provided. The modulation schemes include a plurality of modulation symbols, each of which codes a predefined bit group, which includes one or more bits. The bit groups define different bit positions for bits within the bit groups. The bit positions of the modulation symbols are associated with different error probability levels. Each error probability level defines a probability level of an erroneous bit value at a defined bit position in the bit group, which is obtained by a mapping operation from the modulation symbol transmitted over a radio frequency channel with noise. Binary content to be modulated is provided in form of code blocks I (where i = 1 to n). Each of the code blocks is carried on a corresponding code channel i. The code blocks on the code channels are supplied to the modulation schemes in that each code channel is associated with one predefined bit position of the bit groups to enable a mapping to modulation symbols. The bit groups are formed from the binary content of the code blocks in accordance with the code channel-to-bit position association defined above. The binary content of at least two code blocks is shuffled, distributed, or scattered in accordance with predetermined shuffling, distributing, or scattering rules. The shuffling, distributing, or scattering aims to achieve substantially balanced or same error probability levels for said code channels. The shuffling operation should be performed to achieve a substantially evenly distribution of the binary content upon the involved code blocks.
摘要翻译：提供了用于平衡蜂窝通信中的多符号调制方案的方法和装置。调制方案包括多个调制符号，每个调制符号都编码包括一个或多个比特的预定位组。位组为位组中的位定义不同的位位置。调制符号的位位置与不同的误差概率水平相关联。每个错误概率级别定义在通过具有噪声的射频信道发送的调制符号的映射操作获得的比特组中定义的比特位置处的错误比特值的概率级。以代码块I（其中i = 1至n）的形式提供要调制的二进制内容。每个代码块在对应的代码通道i上承载。代码信道上的代码块被提供给调制方案，因为每个代码通道与位组的一个预定义位位置相关联，以使能映射到调制符号。根据上面定义的代码信道到位位置关联，这些位组由代码块的二进制内容形成。至少两个代码块的二进制内容根据预定的混洗，分布或散布规则进行混洗，分散或分散。混洗，分配或散射旨在实现所述代码信道的基本平衡或相同的错误概率级别。应执行混洗操作以实现二进制内容在所涉及的代码块上的基本均匀分布。

6. 发明申请

WO2011054372A1 METHOD AND APPARATUSES FOR DATA TRANSFER WITHIN A RELAY ENHANCED TELEKOMMUNIKATION NETWORK 审中-公开
标题翻译：在继电器增强电话网络中进行数据传输的方法和装置
公开(公告)号：WO2011054372A1
公开(公告)日：2011-05-12
申请号：PCT/EP2009/064532
申请日：2009-11-03
申请人： NOKIA SIEMENS NETWORKS OY , ZHAO, Zhu Yan , REDANA, Simone , RAAF, Bernhard
发明人： ZHAO, Zhu Yan , REDANA, Simone , RAAF, Bernhard
IPC分类号： H04W72/12
CPC分类号： H04W72/082 , H04B7/15557 , H04B7/15564 , H04B7/2606 , H04W72/1231 , H04W84/047
摘要： A method for scheduling a first user equipment, UE, with a first performance causing a first self interference of a relay system between a first access link extending between the relay system and the first UE and a relay link extending between the relay system and a base station, BS, and scheduling a second UE with a second performance causing a second self interference of the relay system between a second access link extending between the relay system and the second UE and the relay link extending between the relay system and the BS. Thereby, if the first self interference is larger than the second self interference, the first performance is smaller than the second performance. Alternatively, if the first self interference is smaller than the second self interference, the first performance is larger than the second performance.
摘要翻译：一种用于以第一性能来调度第一用户设备的方法，所述第一性能导致在所述中继系统和所述第一UE之间延伸的第一接入链路之间的中继系统的第一自身干扰，以及在所述中继系统与所述基站之间延伸的中继链路站，BS，并且调度具有第二性能的第二UE，其导致在中继系统和第二UE之间延伸的第二接入链路和在中继系统与BS之间延伸的中继链路之间的中继系统的第二自身干扰。因此，如果第一自身干扰大于第二自身干扰，则第一性能小于第二性能。或者，如果第一自身干扰小于第二自身干扰，则第一性能大于第二性能。

7. 发明申请

WO2009014910A2 N-LINKED HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS 审中-公开
标题翻译：用于治疗糖尿病和代谢障碍的N-连锁异位受体激动剂
公开(公告)号：WO2009014910A2
公开(公告)日：2009-01-29
申请号：PCT/US2008069714
申请日：2008-07-10
申请人： METABOLEX INC , MA JINGYUAN , RABBAT CHRISTOPHER J , SONG JIANGAO , CHEN XIN , NASHASHIBI IMAD , ZHAO ZUCHUN , NOVACK AARON , SHI DONG FANG , CHENG PENG , ZHU YAN , MURPHY ALISON
发明人： MA JINGYUAN , RABBAT CHRISTOPHER J , SONG JIANGAO , CHEN XIN , NASHASHIBI IMAD , ZHAO ZUCHUN , NOVACK AARON , SHI DONG FANG , CHENG PENG , ZHU YAN , MURPHY ALISON
IPC分类号： C07D401/14 , C07D401/04 , C07D413/14 , C07D417/14
CPC分类号： C07D401/04 , C07D401/14 , C07D413/14 , C07D417/14
摘要： Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control.
摘要翻译：提供了化合物和方法用于治疗特别是II型糖尿病和与血糖控制不良相关的其它疾病。

8. 发明申请

WO2006020916A2 MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION 审中-公开
标题翻译： PPAR调节剂及其制备方法
公开(公告)号：WO2006020916A2
公开(公告)日：2006-02-23
申请号：PCT/US2005/028822
申请日：2005-08-12
申请人： METABOLEX, INC. , ZHU, Yan , MA, Jingyuan , CHENG, Peng , ZHAO, Zuchun , GREGOIRE, Francine, M. , RAKHMANOVA, Vera, A.
发明人： ZHU, Yan , MA, Jingyuan , CHENG, Peng , ZHAO, Zuchun , GREGOIRE, Francine, M. , RAKHMANOVA, Vera, A.
IPC分类号： A61K31/4965 , A61K31/50 , A61K31/506 , A61K31/53 , C07D403/02
CPC分类号： C07D263/57 , C07D249/06 , C07D249/20 , C07D403/12 , C07D409/10
摘要： The present invention is directed to certain novel compounds represented by Formula (I) and pharmaceutically acceptable salts, solvates, hydrates and prodrugs thereof. The present invention is also directed to methods of making and using such compounds and pharmaceutical compositions containing such compounds to treat or control a number of diseases mediated by PPAR such as glucose metabolism, lipid metabolism and insulin secretion, specifically Type 2 diabetes, hyperinsulinemia, hyperlipidemia, hyperuricemia, hypercholesteremia, atherosclerosis, one or more risk factors for cardiovascular disease, Syndrome X, hypertriglyceridemia, hyperglycemia, obesity and eating disorders.
摘要翻译：本发明涉及由式（I）表示的某些新化合物及其药学上可接受的盐，溶剂化物，水合物和前药。本发明还涉及制备和使用这些化合物和含有这些化合物的药物组合物的方法，以治疗或控制许多由PPAR介导的疾病，如葡萄糖代谢，脂质代谢和胰岛素分泌，特别是2型糖尿病，高胰岛素血症，高脂血症，高尿酸血症，高胆固醇血症，动脉粥样硬化，一种或多种心血管疾病，X综合征，高甘油三酯血症，高血糖症，肥胖症和进食障碍的风险因子。

9. 发明申请

WO2005115384A3 BICYCLIC, SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION 审中-公开
标题翻译：作为PPAR调节剂的双环取代三唑类化合物及其制备方法
公开(公告)号：WO2005115384A3
公开(公告)日：2005-12-29
申请号：PCT/US2005018319
申请日：2005-05-24
申请人： METABOLEX INC , ZHU YAN , MA JINGYUAN , CHENG PENG , ZHAO ZUCHUN , GREGOIRE FRANCINE M , RAKHMANOVA VERA A
发明人： ZHU YAN , MA JINGYUAN , CHENG PENG , ZHAO ZUCHUN , GREGOIRE FRANCINE M , RAKHMANOVA VERA A
IPC分类号： A61K31/4196 , C07D403/12 , C07D405/12
CPC分类号： C07D403/12 , C07D403/06 , C07D403/14 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12
摘要： The present invention is directed to certain novel triazole compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof. The present invention is also directed to methods of making and using such compounds and pharmaceutical compositions containing such compounds to treat or control a number of diseases mediated by PPAR such as glucose metabolism, lipid metabolism and insulin secretion, specifically Type 2 diabetes, hyperinsulemia, hyperlipidemia, hyperuricemia, hypercholesteremia, atherosclerosis, one or more risk factors for cardiovascular disease, Syndrome X, hypertriglyceridemia, hyperglycemia, obesity, and eating disorders.
摘要翻译：本发明涉及某些由式I表示的新型三唑化合物及其药学上可接受的盐，溶剂化物，水合物和前药。本发明还涉及制备和使用这些化合物和含有这些化合物的药物组合物的方法，以治疗或控制许多由PPAR介导的疾病，如葡萄糖代谢，脂质代谢和胰岛素分泌，特别是2型糖尿病，高胰岛素血症，高脂血症，高尿酸血症，高胆固醇血症，动脉粥样硬化，心血管疾病的一种或多种风险因素，X综合征，高甘油三酯血症，高血糖症，肥胖症和进食障碍。

10. 发明申请

WO0041531A3 SERINE PROTEASE INHIBITORS 审中-公开
标题翻译：丝氨酸蛋白酶抑制剂
公开(公告)号：WO0041531A3
公开(公告)日：2001-08-16
申请号：PCT/US0000673
申请日：2000-01-11
申请人： GENENTECH INC , ALIAGAS MARTIN IGNACIO , ARTIS DEAN R , DINA MICHAEL S , FLYGARE JOHN A , GOLDSMITH RICHARD A , MUNROE REGINA A , OLIVERO ALAN G , PASTOR RICHARD , RAWSON THOMAS E , ROBARGE KIRK D , SUTHERLIN DANIEL P , WEESE KENNETH J , ZHOU AIHE , ZHU YAN
发明人： ALIAGAS-MARTIN IGNACIO , ARTIS DEAN R , DINA MICHAEL S , FLYGARE JOHN A , GOLDSMITH RICHARD A , MUNROE REGINA A , OLIVERO ALAN G , PASTOR RICHARD , RAWSON THOMAS E , ROBARGE KIRK D , SUTHERLIN DANIEL P , WEESE KENNETH J , ZHOU AIHE , ZHU YAN
IPC分类号： C07D333/34 , A61K31/18 , A61K31/196 , A61K31/216 , A61K31/381 , A61P7/02 , A61P9/10 , C07C257/18 , C07C311/05 , C07C311/08 , C07C311/13 , C07C311/18 , C07C311/29 , C07C311/51 , C07C257/16 , C07C311/06 , C07C311/21
CPC分类号： C07C257/18 , C07C311/05 , C07C311/08 , C07C311/13 , C07C311/18 , C07C311/29 , C07C311/51
摘要： Compounds having structure (A) are useful to inhibit serine protease enzymes, such as TF/factor VIIa, factor Xa, thrombin and kallikrein. These compounds may be used in methods of preventing and/or treating clotting disorders.
摘要翻译：具有结构（A）的化合物可用于抑制丝氨酸蛋白酶，例如TF /因子VIIa，因子Xa，凝血酶和激肽释放酶。这些化合物可用于预防和/或治疗凝血障碍的方法。

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