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1. 发明申请

WO2009075923A2 6, 11-BRIDGED BIARYL MACROLIDES 审中-公开
标题翻译： 6,11-BRIDGED BIARYL MACROLIDES
公开(公告)号：WO2009075923A2
公开(公告)日：2009-06-18
申请号：PCT/US2008/076731
申请日：2008-09-17
申请人： ENANTA PHARMACEUTICALS, INC. , KIM, In, Jong , LIU, Tongzhu , LONG, Jiang , WANG, Guoqiang , QUI, Yao-ling , KIM, Heejin , WANG, Yanchun , PHAN, Ly, Tam , OR, Yat, Sun
发明人： KIM, In, Jong , LIU, Tongzhu , LONG, Jiang , WANG, Guoqiang , QUI, Yao-ling , KIM, Heejin , WANG, Yanchun , PHAN, Ly, Tam , OR, Yat, Sun
IPC分类号： C07H17/08 , A61K31/7052
CPC分类号： C07H17/08 , C07D213/69 , C07D213/80 , C07D309/40 , C07D498/12
摘要： The present invention discloses compounds of formula I, II or, or pharmaceutically acceptable salts, esters, or prodrugs thereof: (formulas) which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
摘要翻译：本发明公开了式I，II或其药学上可接受的盐，酯或前药的化合物：表现出抗菌特性的式（式）。本发明还涉及包含前述化合物的药物组合物，用于向需要抗生素治疗的受试者施用。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。本发明还包括制备本发明化合物的方法。

2. 发明申请

WO2006078450A1 9A, 11-2C-BICYCLIC 9A-AZALIDE DERIVATIVES 审中-公开
标题翻译： 9A，11-2C-双环9A-嗪化合物衍生物
公开(公告)号：WO2006078450A1
公开(公告)日：2006-07-27
申请号：PCT/US2006/000202
申请日：2006-01-04
申请人： ENANTA PHARMACUETICALS, INC. , OR, Yat, Sun , PHAN, Ly, Tam , WANG, Guoqiang , WANG, Yanchun , PENG, Yulin
发明人： OR, Yat, Sun , PHAN, Ly, Tam , WANG, Guoqiang , WANG, Yanchun , PENG, Yulin
IPC分类号： A61K31/70 , C07H17/08
CPC分类号： C07H17/08
摘要： The present invention discloses compounds of formulae (I) and (II), or pharmaceutically acceptable salts, esters, or prodrugs thereof, which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
摘要翻译：本发明公开了具有抗菌性质的式（I）和（II）化合物或其药学上可接受的盐，酯或前药。本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。本发明还包括制备本发明化合物的方法。

3. 发明申请

WO2005030227A1 9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES 审中-公开
标题翻译： 9a，11-3C-双丙基9a-马来酸衍生物
公开(公告)号：WO2005030227A1
公开(公告)日：2005-04-07
申请号：PCT/US2004/030780
申请日：2004-09-21
申请人： ENANTA PHARMACEUTICALS, INC. , WANG, Guoqiang , PENG, Yulin , WANG, Yanchun , PHAN, Ly, Tam , OR, Yat, Sun
发明人： WANG, Guoqiang , PENG, Yulin , WANG, Yanchun , PHAN, Ly, Tam , OR, Yat, Sun
IPC分类号： A61K31/70
CPC分类号： C07H17/08
摘要： The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof, which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
摘要翻译：本发明公开了具有抗菌性质的式（I）化合物或其药学上可接受的盐，酯或前药。本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。本发明还包括制备本发明化合物的方法。

4. 发明申请

WO2009137737A3 ANTI-BACTERIAL ACTIVITY OF 9-HYDROXY DERIVATIVES OF 6, 11-BICYCLOLIDES 审中-公开
公开(公告)号：WO2009137737A3
公开(公告)日：2009-11-12
申请号：PCT/US2009/043225
申请日：2009-05-08
申请人： ENANTA PHARMACEUTICALS, INC. , IYENGAR, Rajesh , WANG, Yanchun , PHAN, Ly, Tam , OR, Yat, Sun
发明人： IYENGAR, Rajesh , WANG, Yanchun , PHAN, Ly, Tam , OR, Yat, Sun
IPC分类号： A01N43/04 , A61K31/70
摘要： The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit superior antibacterial properties, particularly against Haemophilus influenzae . The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

5. 发明申请

WO2009075923A3 6, 11-BRIDGED BIARYL MACROLIDES 审中-公开
标题翻译： 6，11-BRIDGED BIARYL MACROLIDES
公开(公告)号：WO2009075923A3
公开(公告)日：2009-09-24
申请号：PCT/US2008076731
申请日：2008-09-17
申请人： ENANTA PHARM INC , KIM IN JONG , LIU TONGZHU , LONG JIANG , WANG GUOQIANG , QUI YAO-LING , KIM HEEJIN , WANG YANCHUN , PHAN LY TAM , OR YAT SUN
发明人： KIM IN JONG , LIU TONGZHU , LONG JIANG , WANG GUOQIANG , QUI YAO-LING , KIM HEEJIN , WANG YANCHUN , PHAN LY TAM , OR YAT SUN
IPC分类号： C07D401/00
CPC分类号： C07H17/08 , C07D213/69 , C07D213/80 , C07D309/40 , C07D498/12
摘要： The present invention discloses compounds of formula I, II or, or pharmaceutically acceptable salts, esters, or prodrugs thereof: (formulas) which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
摘要翻译：本发明公开了式I，II或其药学上可接受的盐，酯或前药的化合物：具有抗菌性质的（式）。本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。本发明还包括制备本发明化合物的方法。

6. 发明申请

WO2006120369A1 SHOWER WASTE PUMP CONTROL 审中-公开
标题翻译：淋浴废水泵控制
公开(公告)号：WO2006120369A1
公开(公告)日：2006-11-16
申请号：PCT/GB2006/000579
申请日：2006-02-20
申请人： DLP LIMITED , WANG, Yanchun , STIMPSON, Robert, William , LOCK, Graham, Robin , SELF, James, Edward , PARSONS, Nicholas
发明人： WANG, Yanchun , STIMPSON, Robert, William , LOCK, Graham, Robin , SELF, James, Edward , PARSONS, Nicholas
IPC分类号： F04D15/02 , F04B49/06
CPC分类号： F04D15/0218 , F04B49/065
摘要： A control device (10) for controlling a shower waste pump, comprises a housing (12) which is mountable to a supporting surface, pump setting means (14) located in and/or on the housing (12), and over-run setting means (16) located in and/or on the housing (12). The pump setting means (14), by way of a control element, preferably a manually adjustable potentiometer (42), allows selective setting of a maximum pumping capacity of the waste pump. The over-run setting means (16), also by way of a control element (48), allows selective setting of an over-run period from a predetermined range during which the waste pump continues to operate after fluid flow through the waste pump has ceased or substantially ceased. The over-run setting means (16) and the pump setting means (14) together can optimise operation of the waste pump, so that the over- run period of the waste pump can be set based on the selected maximum pumping capacity.
摘要翻译：用于控制淋浴废水泵的控制装置（10）包括可安装到支撑表面的壳体（12），位于壳体（12）中和/或壳体（12）上的泵设置装置（14），以及过度设定位于壳体（12）和/或壳体（12）上的装置（16）。泵设置装置（14）通过控制元件优选地是可手动调节的电位计（42），允许选择性地设定废水泵的最大泵送能力。超控设定装置（16）也通过控制元件（48），允许选择性地设定从流过废液泵的流体流过的废水泵继续工作的预定范围的过运行时段停止或基本停止。过冲设定装置（16）和泵设定装置（14）可一起优化废水泵的运行，从而可以根据所选择的最大泵送能力来设定废水泵的运行周期。

7. 发明申请

WO2006119313A2 6-11 BRIDGED OXIME ERYTHROMYCIN DERIVATIVES 审中-公开
标题翻译： 6-11桥联氧化铁蛋白衍生物
公开(公告)号：WO2006119313A2
公开(公告)日：2006-11-09
申请号：PCT/US2006016882
申请日：2006-05-02
申请人： ENANTA PHARM INC , WANG GUOQIANG , PHAN LY TAM , OR YAT SUN , QIU YAO-LING , NIU DEQIANG , PENG YULIN , BUSUYEK MARINA , WANG YANCHUN , NAKAJIMA SUANNE
发明人： WANG GUOQIANG , PHAN LY TAM , OR YAT SUN , QIU YAO-LING , NIU DEQIANG , PENG YULIN , BUSUYEK MARINA , WANG YANCHUN , NAKAJIMA SUANNE
IPC分类号： C07H17/08 , A61K31/7052
CPC分类号： C07H17/08
摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof (see formula I) which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes processes by which to make the compounds of the present invention.
摘要翻译：本发明公开了具有抗菌性质的式I化合物或其药学上可接受的盐，酯或前药（参见式I）。本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。本发明还包括制备本发明化合物的方法。

8. 发明申请

WO2009137737A2 ANTI-BACTERIAL ACTIVITY OF 9-HYDROXY DERIVATIVES OF 6, 11-BICYCLOLIDES 审中-公开
标题翻译： 6,11-二羟基苯甲酸的9-羟基衍生物的抗菌活性
公开(公告)号：WO2009137737A2
公开(公告)日：2009-11-12
申请号：PCT/US2009043225
申请日：2009-05-08
申请人： ENANTA PHARM INC , IYENGAR RAJESH , WANG YANCHUN , PHAN LY TAM , OR YAT SUN
发明人： IYENGAR RAJESH , WANG YANCHUN , PHAN LY TAM , OR YAT SUN
IPC分类号： A61K31/7048 , A61P31/04 , C07H17/08
CPC分类号： A61K31/706 , A61K31/7056 , C07H17/08
摘要： The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit superior antibacterial properties, particularly against Haemophilus influenzae. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
摘要翻译：本发明公开了式（I）化合物或其药学上可接受的盐，酯或前药：其表现出优异的抗菌性，特别是抗流感嗜血杆菌。本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。本发明还包括制备本发明化合物的方法。

9. 发明申请

WO2007128951A1 IMPROVEMENTS IN AND RELATING TO ELECTRIC SHOWERS 审中-公开
标题翻译：电动显示器的改进和相关
公开(公告)号：WO2007128951A1
公开(公告)日：2007-11-15
申请号：PCT/GB2007/000893
申请日：2007-03-15
申请人： DLP LIMITED , STIMPSON, Robert, William , WANG, Yanchun , SELF, James, Edward , JONES, Graham
发明人： STIMPSON, Robert, William , WANG, Yanchun , SELF, James, Edward , JONES, Graham
IPC分类号： B05B1/24 , F24H9/20 , G05D23/19 , F24H1/10 , H01R31/02
CPC分类号： E03C1/044 , B05B1/18 , B05B1/24 , B05B12/00 , E03C1/041 , F24D19/1051 , F24H1/102 , F24H1/162 , F24H9/2028 , H01R4/363 , H01R9/2416 , H01R43/005 , H03K17/964 , Y10T137/6606
摘要： An electric shower water heater unit for connection to a water supply and a mains electricity supply comprises a housing having a shower water outlet to which a shower hose is connectable; an electric water heater housed in the housing and fluidly connectable to a water supply outlet of the water supply and electrically connectable to the mains electricity supply, the electric water heater supplying water to the shower water outlet of the housing; a user-operable controller (20) for controlling a temperature and a flow rate of water supplied to the shower water outlet of the housing, and a control circuit which is housed in the housing and which controls the electric water heater based on inputs received from the user-operable controller (20). The user-operable controller includes a touch-pressure sensitive element (40, 49) for pressing by a user and which is in communication with the control circuit. The control circuit only controls the electric water heater when a pressure imparted by a user pressing the touch-pressure sensitive element (40, 49) is equal to or greater than a predetermined ivalue.
摘要翻译：用于连接到供水和电源的电动淋浴热水器单元包括：具有淋浴水出口的壳体，淋浴软管可连接到淋浴水出口; 电热水器，其容纳在所述壳体中并且可流体地连接到所述供水的供水出口并且可电连接到所述主电源，所述电热水器将水供应到所述壳体的淋浴水出口; 用于控制供给到壳体的淋浴水出口的水的温度和流量的用户可操作的控制器（20），以及控制电路，其被容纳在壳体中，并且基于从所述用户可操作的控制器（20）。用户可操作的控制器包括用于按压用户并与控制电路通信的触敏压力元件（40,49）。当用户按压感压元件（40,49）所施加的压力等于或大于预定值时，控制电路仅控制电热水器。

10. 发明申请

WO2007054667A1 DIAPHRAGM PUMP 审中-公开
标题翻译： DIAPHRAGM泵
公开(公告)号：WO2007054667A1
公开(公告)日：2007-05-18
申请号：PCT/GB2006/004086
申请日：2006-11-02
申请人： DLP LIMITED , STIMPSON, Robert, William , WANG, Yanchun
发明人： STIMPSON, Robert, William , WANG, Yanchun
IPC分类号： F04B43/02 , F04B53/22
CPC分类号： F04B53/105 , F04B43/02 , F04B53/22
摘要： A diaphragm pump for a pumped shower waste, comprises a diaphragm housing (12), a diaphragm (34) removably held in the diaphragm housing (12), an openable cover (16) on the diaphragm housing (12) for accessing the diaphragm (34), an electric motor (14), a connecting member (40) positioned in the diaphragm housing (12) and movable by the electric motor (14), and a non-screw-threaded twist and lock fastener (62) which releasably engages the diaphragm (34) with the connecting member (40). The diaphragm (34) can thus be disengaged and removed from the connecting member (40) without the use of a screwdriver.
摘要翻译：一种用于抽吸淋浴废物的隔膜泵，包括隔膜壳体（12），可移除地保持在隔膜壳体（12）中的隔膜（34），隔膜壳体（12）上的可开启盖（16），用于接近隔膜 34），电动机（14），位于隔膜壳体（12）中并可通过电动机（14）移动的连接构件（40），以及可释放的非螺纹扭转和锁定紧固件（62）将所述隔膜（34）与所述连接构件（40）接合。因此，隔膜（34）可以在不使用螺丝刀的情况下从连接构件（40）脱离和移除。

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