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1. 发明申请

WO2013159331A1 OPTICAL FIBER CONNECTOR 审中-公开
标题翻译：光纤连接器
公开(公告)号：WO2013159331A1
公开(公告)日：2013-10-31
申请号：PCT/CN2012/074814
申请日：2012-04-27
申请人： 3M INNOVATIVE PROPERTIES COMPANY , HU, Guanpeng , WANG, Jianhua
发明人： HU, Guanpeng , WANG, Jianhua
IPC分类号： G02B6/36
CPC分类号： G02B6/3858 , G02B6/3806 , G02B6/3846 , G02B6/3847 , G02B6/3849 , G02B6/3887 , G02B6/3893
摘要： An optical fiber connector (100) is provided, which comprises: a housing (112) configured to mate with a receptacle; a gripping device (140) to grip an optical fiber (135), the gripping device (140) including a fiber gripping element (142) and an actuating cap (144) configured to engage the gripping element (142); a collar body (120) disposed in the housing (112), wherein the collar body (120) includes a ferrule (132) securely disposed in an opening (121) of the collar body (120), the ferrule (132) including a central bore that defines an axis, and a housing portion (123) disposed in a generally central portion of the collar body (120) and having an opening (122) to receive the gripping device (140), wherein the gripping element (142) comprises a ductile material having a focus hinge that couples first and second element arms and wherein a first portion of the gripping element (142) includes a fiber gripping channel to clamp an optical fiber (135) received therein upon actuation by the actuating cap (144); a backbone (116) to retain the collar body (120) within the housing (112), the backbone (116) including a fiber jacket clamping portion (119) to clamp a jacket portion (136) of the optical fiber (135); and a boot (180) attachable to a portion of the backbone (116), wherein the boot (180) actuates the fiber jacket clamping portion (119) of the backbone (116) upon attachment to the backbone (116).
摘要翻译：提供了一种光纤连接器（100），其包括：构造成与插座配合的壳体（112）; 夹持装置（140），用于夹持光纤（135），所述夹持装置（140）包括纤维夹持元件（142）和构造成接合所述夹紧元件（142）的致动帽（144）; 设置在所述壳体（112）中的轴环（120），其中所述轴环主体（120）包括牢固地设置在所述轴环主体（120）的开口（121）中的套圈（132），所述套圈（132）包括限定轴线的中心孔和设置在所述轴环本体（120）的大致中心部分中并具有用于容纳所述夹持装置（140）的开口（122）的壳体部分（123），其中所述夹紧元件（142）包括具有聚焦铰链的延性材料，所述聚焦铰链联接第一和第二元件臂，并且其中所述夹持元件（142）的第一部分包括纤维夹持通道，以在通过所述致动帽（144）致动时夹持容纳在其中的光纤（135））; 所述主体（116）包括用于夹持所述光纤（135）的护套部分（136）的光纤护套夹持部分（119）;所述主体（116）以及可附接到所述骨架（116）的一部分的靴子（180），其中所述靴子（180）在附接到所述骨架（116）时致动所述骨架（116）的纤维套夹紧部分（119）。

2. 发明申请

WO2012055102A1 PANEL FILTER WITH REDUCED RESTRICTION 审中-公开
标题翻译：具有减少限制的面板过滤器
公开(公告)号：WO2012055102A1
公开(公告)日：2012-05-03
申请号：PCT/CN2010/078173
申请日：2010-10-27
申请人： CUMMINS FILTRATION IP INC. , ZOU, Jing , WANG, Jianhua , VENKATARAMAN, Kaarthik , KAZDA, Cara R. , LUKASAVITZ, John C. , BANNISTER, Robert A. , KENDALL, Orvin D. , SCHWARTZ, Scott W.
发明人： ZOU, Jing , WANG, Jianhua , VENKATARAMAN, Kaarthik , KAZDA, Cara R. , LUKASAVITZ, John C. , BANNISTER, Robert A. , KENDALL, Orvin D. , SCHWARTZ, Scott W.
IPC分类号： F02M35/024 , B01D46/00
CPC分类号： F02M35/02491 , B01D46/10 , B01D46/125 , B01D2275/206 , B01D2277/20 , F02M35/02425 , F02M35/02433 , Y10T29/49716
摘要： A filter assembly (30), panel filter element (38) and method for servicing the filter assembly (30) are provided. The filter assembly (30) includes a housing (32) having an inlet (34) and an outlet (36), and the panel filter element (38) including a filter media (40) in the housing (32) for filtering fluid from the inlet (34) to the outlet (36). The panel filter element (38) is configured for reducing inlet flow restriction from the housing inlet (34) into an inlet plenum (42) and reducing outlet flow restriction from an outlet plenum (44) to the housing outlet (36).
摘要翻译：提供了一种过滤器组件（30），面板过滤元件（38）和用于维修过滤组件（30）的方法。过滤器组件（30）包括具有入口（34）和出口（36）的壳体（32），并且所述面板过滤元件（38）包括在所述壳体（32）中的过滤介质（40）到出口（36）的入口（34）。面板过滤元件（38）构造成用于减小从壳体入口（34）进入入口压力室（42）的入口流量限制，并减少从出口压力室（44）到壳体出口（36）的出口流量限制。

3. 发明申请

WO2022006780A1 MANUFACTURE OF COMPOUNDS AND COMPOSITIONS FOR INHIBITING ACTIVITY OF SHP2 审中-公开
公开(公告)号：WO2022006780A1
公开(公告)日：2022-01-13
申请号：PCT/CN2020/100882
申请日：2020-07-08
申请人： NOVARTIS AG , FEI, Zhongbo , LI, Wei , YU, Huangchao , JIA, Huanqing , WANG, Jianhua
发明人： FEI, Zhongbo , LI, Wei , YU, Huangchao , JIA, Huanqing , WANG, Jianhua
IPC分类号： C07D211/62 , C07D401/12 , C07D211/26 , C07D211/22 , C07D213/127 , C07D491/107 , A61P35/00 , A61K31/497
摘要： Provided herein is a method for the manufacture of a compound of Formula I or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II with a compound of the formula III according to the following reaction scheme, wherein LG, A, n, m and p are as defined in the Summary of the Invention, said manufacture including the manufacture and use of a compound of the formula VI, wherein R1 is a secondary amino protecting group and R5 is unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or unsubstituted or substituted aryl.

4. 发明申请

WO2008020075A1 TRANSGLUTAMINASE VARIANTS WITH IMPROVED SPECIFICITY 审中-公开
标题翻译：具有改善特异性的转谷氨酰胺酶变体
公开(公告)号：WO2008020075A1
公开(公告)日：2008-02-21
申请号：PCT/EP2007/058571
申请日：2007-08-17
申请人： NOVO NORDISK HEALTH CARE AG , HU, Zhixiang , ZHAO, Xin , WANG, Jianhua , CHANG, Chih-Chuan , NØRSKOV-LAURITSEN, Leif
发明人： HU, Zhixiang , ZHAO, Xin , WANG, Jianhua , CHANG, Chih-Chuan , NØRSKOV-LAURITSEN, Leif
IPC分类号： C07K14/61 , C12N9/10 , C12N15/54
CPC分类号： C12N9/1044 , A61K47/60 , C07K14/61
摘要： Variants of transglutaminase from Streptoverticillium ladakanum, which variants have improved selectivity for Gln-141 of human growth hormone are provided.
摘要翻译：提供了来自链霉菌（Streptoverticillium ladakanum）的转谷氨酰胺酶的变体，其变体对人生长激素的Gln-141具有改善的选择性。

5. 发明申请

WO2013026194A1 FOUR-LENS MODULE FOR IMAGE CAPTURE 审中-公开
标题翻译：用于图像捕获的四镜头模块
公开(公告)号：WO2013026194A1
公开(公告)日：2013-02-28
申请号：PCT/CN2011/078769
申请日：2011-08-23
申请人： ETHER PRECISION, INC. , WANG, Jianhua , LUSINCHI, Jean-Pierre , QIU, Xiaoxiong , WU, Wanghu
发明人： WANG, Jianhua , LUSINCHI, Jean-Pierre , QIU, Xiaoxiong , WU, Wanghu
IPC分类号： G02B9/34
CPC分类号： G02B9/34 , G02B13/001 , G02B13/004 , G02B27/0025 , H01L27/14625 , H04N5/2254
摘要： An optical module having an object side and an image side; the module comprising, from the object side to the image side: a first positive meniscus lens having a convergence C1, made of a material having a refractive index Nd1 and an Abbc number Vd1, a second negative meniscus lens having a convergence C2 made of a material having a refractive index Nd2 and an Abbc number Vd2, a third positive meniscus lens, having a convergence C3, made of a material having a refractive index Nd3 and an Abbc number Vd3, a fourth negative lens having a convergence C4, made of a material having a refractive index Nd4 and an Abbc number Vd4, wherein: 1.1≤C1/C≤ 1.35 II C1/C2 II ≥ 2 0.5≤ C1/C3≤ 1.1 Cl/Vd1≤
摘要翻译：具有物体侧和像侧的光学模块; 该模块包括从物体侧到像侧：具有由具有折射率Nd1和Abbc数Vd1的材料制成的会聚C1的第一正弯月形透镜，具有由具有折射率Nd2和Abbc数Vd2的材料，具有由具有折射率Nd3和Abbc数Vd3的材料制成的会聚C3的第三正弯月透镜，具有会聚C4的第四负透镜，由具有折射率Nd4和Abbc数Vd4的材料，其中：1.1 = C1 / C = 1.35 II C1 / C2 II = 2 0.5 = C1 / C3 = 1.1Cl / Vd1 = <5.2 II C2 / Vd2 II = （Ci / Vdi）II <4，i = 1〜4。

6. 发明申请

WO2009061756A1 BIFOCAL OCT SYSTEM FOR IMAGING ACCOMMODATION OF THE EYE 审中-公开
标题翻译：用于成像眼睛适应性的双峰OCT系统
公开(公告)号：WO2009061756A1
公开(公告)日：2009-05-14
申请号：PCT/US2008/082393
申请日：2008-11-05
申请人： UNIVERSITY OF MIAMI , JIAO, Shuliang , WANG, Jianhua
发明人： JIAO, Shuliang , WANG, Jianhua
IPC分类号： A61B6/00
CPC分类号： A61B5/0059 , A61B3/102 , A61B3/1173 , A61B5/0066
摘要： The present invention advantageously provides a method and system for increasing imaging depth. In particular, the present invention provides an OCT system that includes two or more linked OCT engines operating at different wavelengths to image different depths at different focal planes. The multiple independent images are then combined, to effectively extend the operating depth of an OCT system and thereby provide enhanced eye accommodation research capabilities, as well as the capability to enhance or otherwise extend the imaging depth for other tissue of interest.
摘要翻译：本发明有利地提供了一种用于增加成像深度的方法和系统。特别地，本发明提供一种OCT系统，其包括以不同波长工作的两个或更多个连接的OCT引擎，以在不同焦平面上成像不同的深度。然后组合多个独立图像，以有效地延长OCT系统的操作深度，从而提供增强的眼睛适应性研究能力，以及增强或以其他方式延伸其他感兴趣组织的成像深度的能力。

7. 发明申请

WO2009058850A1 SYSTEM AND METHOD FOR IMAGING TEAR FILM ON AN OCULAR SURFACE 审中-公开
标题翻译：用于在眼表面上成像眼膜的系统和方法
公开(公告)号：WO2009058850A1
公开(公告)日：2009-05-07
申请号：PCT/US2008/081568
申请日：2008-10-29
申请人： UNIVERSITY OF MIAMI , WANG, Jianhua , JIAO, Shuliang
发明人： WANG, Jianhua , JIAO, Shuliang
IPC分类号： A61B5/16 , A61B8/06
CPC分类号： A61B3/101 , A61B3/102 , A61B5/0059 , A61B5/0066
摘要： A method and system for imaging tear film on an ocular surface. The method and system includes depositing a contrasting agent onto the ocular surface. The method may further include positioning an ocular device about the ocular surface. An OCT scanner may then image the ocular surface to detect impairments in the boundary layer between the tear film and the ocular device or the boundary between the tear meniscus and the ocular device.
摘要翻译：一种用于在眼表上成像泪膜的方法和系统。该方法和系统包括将对比剂沉积在眼表面上。该方法还可以包括围绕眼表面定位眼睛装置。然后，OCT扫描仪可以对眼表进行成像，以检测泪液膜和眼部装置之间的边界层中的损伤或泪液弯液面与眼睛装置之间的边界。

8. 发明申请

WO2008020074A1 TRANSGLUTAMINASE VARIANTS WITH IMPROVED SPECIFICITY 审中-公开
标题翻译：具有改善特异性的转谷氨酰胺酶变体
公开(公告)号：WO2008020074A1
公开(公告)日：2008-02-21
申请号：PCT/EP2007/058569
申请日：2007-08-17
申请人： NOVO NORDISK HEALTH CARE AG , NØRSKOV-LAURITSEN, Leif , JOHANSEN, Nils, Langeland , HU, Zhixiang , ZHAO, Xin , WANG, Jianhua
发明人： NØRSKOV-LAURITSEN, Leif , JOHANSEN, Nils, Langeland , HU, Zhixiang , ZHAO, Xin , WANG, Jianhua
IPC分类号： C07K14/61 , C12N9/10 , C12N15/54
CPC分类号： C12N9/1044 , A61K47/60 , C07K14/61
摘要： Variants of transglutaminase from S mobareanse , which variants have improved selectivity against Gln-40 and Gln-141 of human growth hormone are provided.
摘要翻译：提供了来自S mobareanse的转谷氨酰胺酶的变体，其变体对人生长激素的Gln-40和Gln-141的选择性提高。

9. 发明申请

WO2022007502A1 MANUFACTURE OF COMPOUNDS AND COMPOSITIONS FOR INHIBITING SHP2 审中-公开
公开(公告)号：WO2022007502A1
公开(公告)日：2022-01-13
申请号：PCT/CN2021/094139
申请日：2021-05-17
申请人： NOVARTIS AG , FEI, Zhongbo , LI, Wei , YU, Huangchao , JIA, Huanqing , WANG, Jianhua
发明人： FEI, Zhongbo , LI, Wei , YU, Huangchao , JIA, Huanqing , WANG, Jianhua
IPC分类号： C07D211/62 , C07D491/107 , C07D401/12 , C07D211/26 , C07D211/22 , C07D213/127 , A61K31/497 , A61P35/00
摘要： Provided herein is a method for the manufacture of a compound of Formula (I) or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula (II) with a compound of the formula (III) according to the following reaction scheme: wherein LG, A, n, m and p are as defined herein, said manufacture including the manufacture and use of a compound of the formula (VI): wherein R1 is a secondary amino protecting group and R5 is unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or unsubstituted or substituted aryl.

10. 发明申请

WO2013159332A1 OPTICAL FIBER CONNECTOR POLISHING APPARATUS AND METHOD 审中-公开
标题翻译：光纤连接器抛光装置和方法
公开(公告)号：WO2013159332A1
公开(公告)日：2013-10-31
申请号：PCT/CN2012/074816
申请日：2012-04-27
申请人： 3M INNOVATIVE PROPERTIES COMPANY , WANG, Jianhua , HU, Guanpeng , PEPIN, Ronald P.
发明人： WANG, Jianhua , HU, Guanpeng , PEPIN, Ronald P.
IPC分类号： B24B19/22
CPC分类号： B24B19/226 , G02B6/3863
摘要： A polishing apparatus for polishing an optical fiber connector is disclosed. The polishing apparatus has a base portion to support a polishing media; and a polishing puck. The polishing puck includes a connector mount, to receive and hold the optical fiber connector secured to a terminal end of an optical fiber, and a polishing gear configured to engage with a ring gear disposed in the base portion such that a fiber tip of optical fiber mounted in the optical connector traces a roulette pattern on the polishing media upon rotational engagement of the polishing gear within the ring gear.
摘要翻译：公开了一种用于抛光光纤连接器的抛光装置。抛光装置具有支撑抛光介质的基部; 和抛光盘。抛光盘包括连接器安装件，用于接收和保持固定在光纤终端上的光纤连接器，以及抛光齿轮，其配置成与设置在基座部分中的环形齿轮接合，使得光纤的光纤尖端安装在光学连接器中的轮盘图案在抛光齿轮在齿圈内的旋转接合时跟踪抛光介质上的轮盘图案。

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