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1. 发明申请

WO2007127979A3 FLUID QUICK CONNECTOR WITH MULTI-SHOT INTEGRAL SEAL CARRIER 审中-公开
标题翻译：流体快速连接器与多发集成式密封运输车
公开(公告)号：WO2007127979A3
公开(公告)日：2008-07-10
申请号：PCT/US2007067786
申请日：2007-04-30
申请人： COOPER STANDARD AUTOMOTIVE INC , WALKER DANIEL HOWARD , STUART TIMOTHY JON , KREINER KEVIN JOHN , BENGRY PRESTON LEWIS
发明人： WALKER DANIEL HOWARD , STUART TIMOTHY JON , KREINER KEVIN JOHN , BENGRY PRESTON LEWIS
IPC分类号： F16L37/00
CPC分类号： F16L37/144 , F16L2201/10
摘要： A fluid quick connector includes a multi-shot molded seal element fixed in a bore of a connector housing. In one aspect, the seal element is fixed on a carrier which is itself fixedly inserted into the bore of the housing. The seal element may include an inner seal portion disposed on an inner surface of the carrier to engage an endform and a unitary outer seal portion disposed on an outer surface of the carrier to sealingly engage the inner surface of the housing bore. In another aspect, the seal element includes an edge portion disposed about an end of the carrier and unitary with the inner and outer seal portions. In another aspect, the seal element is multi-shot molded within an annular recess in an inner surface of the bore of the connector housing to sealingly engage the endform.
摘要翻译：流体快速连接器包括固定在连接器壳体的孔中的多点模制密封元件。在一个方面，密封元件固定在本身固定地插入壳体的孔中的托架上。密封元件可以包括设置在承载件的内表面上的内部密封部分，以接合端部件和设置在承载件的外表面上的整体外部密封部分，以密封地接合壳体孔的内表面。在另一方面，密封元件包括围绕托架的端部设置并与内密封部分和外密封部分整体形成的边缘部分。在另一方面，密封元件在连接器壳体的孔的内表面内的环形凹部内多次模制，以密封地接合端面。

2. 发明申请

WO2008060450A2 MULTIPLE LINE POWERED ROPE ASCENDER AND PORTABLE HOIST 审中-公开
标题翻译：多线驱动绳索升降机和便携式起重机
公开(公告)号：WO2008060450A2
公开(公告)日：2008-05-22
申请号：PCT/US2007/023596
申请日：2007-11-09
申请人： ATLAS DEVICES LLC , FOFONOFF, Timothy , BALL, Nathan , WALKER, Daniel , SCHMID, Bryan
发明人： FOFONOFF, Timothy , BALL, Nathan , WALKER, Daniel , SCHMID, Bryan
IPC分类号： B66D1/36
CPC分类号： B66C13/08 , B66D1/46
摘要： A multiple-rope or multiple-cable pulling device is provided for positioning a load. The device can include an electronic controller that interprets a user's input from an interface such as a trigger or a joystick, and activates electronically controlled motors that drive one or more rope pulling mechanisms, such as winches. When the winches pull in or pay out cable in accordance with the controller's demand, the load is moved along the desired trajectory as specified by the user through the device interface.
摘要翻译：提供多绳或多绳拉动装置用于定位负载。该设备可以包括电子控制器，其解释来自诸如触发器或操纵杆的接口的用户输入，并且激活驱动一个或多个绳索牵引机构（例如绞车）的电子控制的电机。当绞盘根据控制器的要求拉入或放出电缆时，负载沿用户通过设备接口指定的期望轨迹移动。

3. 发明申请

WO2008041118A3 PYRIDO[4,3-D]PYRIMIDIN-4(3H)-ONE DERIVATIVES AS CALCIUM RECEPTOR ANTAGONISTS 审中-公开
公开(公告)号：WO2008041118A3
公开(公告)日：2008-04-10
申请号：PCT/IB2007/002976
申请日：2007-09-26
申请人： PFIZER PRODUCTS INC. , BI, Feng , DIDIUK, Mary, Theresa , GRIFFITH, David, Andrew , GUZMAN-PEREZ, Angel , LIU, Kevin Kun-Chin , WALKER, Daniel, Patrick
发明人： BI, Feng , DIDIUK, Mary, Theresa , GRIFFITH, David, Andrew , GUZMAN-PEREZ, Angel , LIU, Kevin Kun-Chin , WALKER, Daniel, Patrick
IPC分类号： C07D471/04 , A61K31/519 , A61P19/10
摘要： The present invention is directed to novel pyrido[4,3-d]pyrimidin-4(3H)-one derivatives and pharmaceutically acceptable salts thereof of structural formula (I) wherein the variables R 1 , R 2 , R 3 , R 4 and R 5 are as described herein. Also provided are pharmaceutical compositions comprising the compounds of formula I as well as methods of treatment employing compounds of formula I to treat a disease or disorder characterized by abnormal bone or mineral homeostasis such as hypoparathyroidism, osteoporosis, osteopenia, periodontal disease, Paget's disease, bone fracture, osteoarthritis, rheumatoid arthritis, and humoral hypercalcemia of malignancy.

4. 发明申请

WO2004074292A1 EXO-(T-BUTYL 2R(+))-2-AMINO-7-AZABICYCLO[2.2.1]HEPTANE-7-CARBOXYLATE, INTERMEDIATES, AND PROCESS TO PREPARE AND ISOLATE THEM 审中-公开
标题翻译： EXO-（T-BUTYL 2R（+）） - 2-氨基-7-亚氨基] [2.2.1]庚烷-7-羧酸酯，中间体和制备和分离它们的方法
公开(公告)号：WO2004074292A1
公开(公告)日：2004-09-02
申请号：PCT/IB2004/000430
申请日：2004-02-09
申请人： PHARMACIA & UPJOHN COMPANY , ANJEH, Tizah, Evelyn , FEVIG, Thomas, Lee , LAWSON, Jon, Philip , WALKER, Daniel, Patrick , WISHKA, Donn, Gregory
发明人： ANJEH, Tizah, Evelyn , FEVIG, Thomas, Lee , LAWSON, Jon, Philip , WALKER, Daniel, Patrick , WISHKA, Donn, Gregory
IPC分类号： C07D487/08
CPC分类号： C07D487/08
摘要： The present invention relates to exo -(t-butyl 2 R (+))-2-amino-7-azabicyclo[2.2.1]heptane-7-carboxylate (formula 1) a novel compound, and the process for the preparation thereof, and novel intermediates therein.
摘要翻译：本发明涉及一种新型化合物的外 - （叔丁基2R（+）） - 2-氨基-7-氮杂双环[2.2.1]庚烷-7-羧酸酯（式1）及其制备方法，和其中的新型中间体。

5. 发明申请

WO2003072578A1 AZABICYCLIC COMPOUNDS WITH ALFA7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY 审中-公开
标题翻译：具有ALFA7 NICOTINIC乙酰胆碱受体活性的亚甲基化合物
公开(公告)号：WO2003072578A1
公开(公告)日：2003-09-04
申请号：PCT/US2003/002688
申请日：2003-02-14
申请人： PHARMACIA & UPJOHN COMPANY , JACOBSEN, Eric, Jon , MYERS, Jason, K. , WALKER, Daniel, P. , WISHKA, Donn, G. , REITZ, Steven, C. , PIOTROWSKI, David, W. , ACKER, Brad, A. , GROPPI, Jr. Vincent, E.
发明人： JACOBSEN, Eric, Jon , MYERS, Jason, K. , WALKER, Daniel, P. , WISHKA, Donn, G. , REITZ, Steven, C. , PIOTROWSKI, David, W. , ACKER, Brad, A. , GROPPI, Jr. Vincent, E.
IPC分类号： C07D453/02
CPC分类号： C07D453/02
摘要： The invention provides compounds of Formula I: (1) wherein Azabicyclo is (2) W is a six-membered heterocyclic ring system having 1-2 nitrogen atoms or a 10-membered bicyclic-six-six-fused-ring system having up to two nitrogen atoms within either or both rings, provided that no nitrogen is at a bridge of ten bicyclic-six-six-fused-ring system, and further having 1-2 substituents independently selected from R 3 . These compounds may be in the form of pharamaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharamaceuticals to treat diseases or conditions in which α7 is known t be involved.
摘要翻译：本发明提供了式I化合物：（1）其中氮杂双环是（2）W是具有1-2个氮原子的六元杂环系统或10元双环六六稠环系统，其具有直至任何一个或两个环中的两个氮原子，条件是没有氮位于十二环六六稠合环系统的桥上，并且还具有1-2个独立地选自R3的取代基。这些化合物可以是药用盐或组合物的形式，可以是纯对映体形式或外消旋混合物，并且可用于药用药物以治疗已知α7已知的疾病或病症。

6. 发明申请

WO2003029252A1 AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE 审中-公开
标题翻译：用于治疗疾病的亚硫酸酯替代的氟化异黄酮化合物
公开(公告)号：WO2003029252A1
公开(公告)日：2003-04-10
申请号：PCT/US2002/029827
申请日：2002-10-01
申请人： PHARMACIA & UPJOHN COMPANY , WALKER, Daniel, Patrick , PIOTROWSKI, David, W. , JACOBSEN, Eric, Jon , ACKER, Brad, A. , WISHKA, Donn, G. , REITZ, Steven, Charles , GROPPI, Vincent, E., Jr.
发明人： WALKER, Daniel, Patrick , PIOTROWSKI, David, W. , JACOBSEN, Eric, Jon , ACKER, Brad, A. , WISHKA, Donn, G. , REITZ, Steven, Charles , GROPPI, Vincent, E., Jr.
IPC分类号： C07D453/02
CPC分类号： C07D519/00
摘要： The invention provides compounds of Formula (I), wherein Azabicyclo is formulas (II-VII), W is formulas (VIII-X). These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which α7 is known to be involved.
摘要翻译：本发明提供了式（I）化合物，其中氮杂双环是式（II-VII），W是式（VIII-X）。这些化合物可以是药物盐或组合物，外消旋混合物或其纯对映异构体的形式。式I的化合物可用于已知其中涉及α7的药物中。

7. 发明申请

WO2013025593A1 LOCKING JOINT FOR COLLAPSIBLE LADDERS AND OTHER STRUCTURES 审中-公开
标题翻译：不可避免的梯子和其他结构的锁定接头
公开(公告)号：WO2013025593A1
公开(公告)日：2013-02-21
申请号：PCT/US2012/050548
申请日：2012-08-13
申请人： ATLAS DEVICES, LLC , GALLUP, Benjamin , BALL, Nathan , SCHMID, Bryan , WALKER, Daniel
发明人： GALLUP, Benjamin , BALL, Nathan , SCHMID, Bryan , WALKER, Daniel
IPC分类号： E05D11/10
CPC分类号： E06C1/383 , E06C1/10 , E06C1/32 , E06C1/52 , E06C7/087 , E06C7/50
摘要： A rigid structure such as a ladder is disclosed having rotating hinges that allow the ladder to fold up and/or be disassembled and assembled. The hinge or hinges can be provided between ladder sections with one ladder section having a male hinge element, and another having a female hinge element. A cam element provided with the female hinge element can be moved between an unlocked position in which the ladder sections can rotate with respect to each other, and a locked position in which the structure is rigid.
摘要翻译：公开了诸如梯子的刚性结构，其具有允许梯子折叠和/或拆卸和组装的旋转铰链。铰链或铰链可以设置在梯形部分之间，具有一个具有阳铰链元件的梯形部分，另一个具有阴铰链元件。设置有阴铰链元件的凸轮元件可以在梯形部分可以相对于彼此旋转的解锁位置和结构刚性的锁定位置之间移动。

8. 发明申请

WO2010089057A3 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS 审中-公开
标题翻译：彩色颗粒用于电泳显示
公开(公告)号：WO2010089057A3
公开(公告)日：2010-10-21
申请号：PCT/EP2010000549
申请日：2010-01-29
申请人： MERCK PATENT GMBH , GREINERT NILS , FARRAND LOUISE DIANE , JAMES MARK , SMITH ASHLEY NATHAN , GOULDING MARK JOHN , WALKER DANIEL , KHAN SAFYAN , REYNOLDS PAUL , HAWKINS SUSAN , HUGHES ROY
发明人： GREINERT NILS , FARRAND LOUISE DIANE , JAMES MARK , SMITH ASHLEY NATHAN , GOULDING MARK JOHN , WALKER DANIEL , KHAN SAFYAN , REYNOLDS PAUL , HAWKINS SUSAN , HUGHES ROY
IPC分类号： C08F20/68 , C08L33/08 , C08L33/10 , C09B69/10 , D06P1/00 , G02F1/167
CPC分类号： D06P1/006 , C08F220/14 , C08F220/30 , C08F220/36 , C09B69/106 , G02F1/167 , G02F2001/1678 , C08F220/06
摘要： This invention relates to coloured polymer particles preferably with surface functionality for charge retention, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, colour electrophoretic displays comprising such particle, and new water-soluble dyes.
摘要翻译：本发明涉及优选具有用于电荷保持的表面官能度的着色聚合物颗粒，其制备方法，这些颗粒用于制备电泳装置的用途，包含这种颗粒的彩色电泳显示器和新的水溶性染料。

9. 发明申请

WO2007103035A3 DEVICE TO ENABLE ROPE PULLING FUNCTIONALITY USING A ROTATIONAL POWER SOURCE 审中-公开
标题翻译：使用旋转电源实现鞋带拉伸功能的设备
公开(公告)号：WO2007103035A3
公开(公告)日：2008-01-10
申请号：PCT/US2007004963
申请日：2007-02-27
申请人： ATLAS DEVICES LLC , FOFONOFF TIMOTHY , BALL NATHAN , SCHMID BRYAN , WALKER DANIEL
发明人： FOFONOFF TIMOTHY , BALL NATHAN , SCHMID BRYAN , WALKER DANIEL
IPC分类号： E21B19/22
CPC分类号： B66D1/7415
摘要： A device capable of pulling an object (e.g., a person) by or up a tensioning member (e.g., a rope) is provided. The device can be configured to mate to any location of the tensioning member, and subsequently interface with a rotational power source (such a mechanical drill). Once interfaced, an output of the rotational energy source can be rotationally coupled to a rotating drum of the device wherein the drum is in communication with the tensioning member. With the addition of power, the drum(s) can pull the tensioning member through the device and allow for a continuous force to be applied to an object attached to the device or attached to the tensioning member. The use of such a convenient and low-cost power source allows for an economic, portable, and simple to use device capable of lifting and/or pulling heavy loads.
摘要翻译：提供了能够通过或向上拉动张紧构件（例如绳索）来拉动物体（例如，人物）的装置。该装置可以配置成与张紧构件的任何位置配合，并且随后与旋转动力源（这种机械钻头）接合。一旦接合，旋转能量源的输出可以旋转地耦合到装置的旋转滚筒，其中滚筒与张紧构件连通。通过增加动力，滚筒可以拉动张紧构件穿过该装置并且允许连续的力施加到附接到该装置的物体上或附接到张紧构件上。使用这种方便和低成本的电源允许经济，便携和易于使用的能够提升和/或拉动重负载的装置。

10. 发明申请

WO2004039815A3 COMPOUNDS HAVING BOTH ALPHA7 NACHR AGONIST AND ANTAGONIST ACTIVITY FOR TREATMENT OF CNS DISEASES 审中-公开
标题翻译：具有两种ALPHA7 NACHR激动剂的化合物和用于治疗CNS疾病的拮抗剂活性
公开(公告)号：WO2004039815A3
公开(公告)日：2004-07-22
申请号：PCT/IB0304681
申请日：2003-10-20
申请人： UPJOHN CO , WONG ERIK HO FONG , CORTES-BURGOS LUZ AMPARO , ROGERS BRUCE NELSEN , PIOTROWSKI DAVID WALTER , WALKER DANIEL PATRICK , JACOBSEN ERIC JON , WISHKA DONN GREGORY , ACKER BRAD ALAN
发明人： WONG ERIK HO FONG , CORTES-BURGOS LUZ AMPARO , ROGERS BRUCE NELSEN , PIOTROWSKI DAVID WALTER , WALKER DANIEL PATRICK , JACOBSEN ERIC JON , WISHKA DONN GREGORY , ACKER BRAD ALAN
IPC分类号： C07D453/02 , C07D487/08 , C07D519/00 , A61K31/439
CPC分类号： C07D487/08 , C07D453/02 , Y02P20/55
摘要： The invention discloses compounds that are selective alpha7 nAChR agonists and 5-HT3 antagonists. The compounds are useful for treating many CNS diseases. The compounds have the following Formula (I): Azabicyclo-N(H)-C(=O)-W wherein Azabicyclo is Formula (2) each R1 is independently H, alkyl, or substituted alkyl; R2 is H, alkyl, or substituted alkyl; k is 1 or 2, provided that one R2 is other than H when k is 2; R3 is H, alkyl, or an amino protecting group; W is Formula (3); W is CH or N; W is O, N(R4), N(C(O)R4), or S; W is O, N(R4), N(C(O)R4), or S; R is H, F, Cl, Br, I, alkyl, substituted alkyl, or alkynyl; Alkyl is both straight- and branched-chain moieties having from 1-6 carbon atoms.
摘要翻译：本发明公开了选择性α7nAChR激动剂和5-HT3拮抗剂的化合物。该化合物可用于治疗许多CNS疾病。化合物具有下式（I）：氮杂双环-N（H）-C（= O）-W 0，其中，氮杂双环是式（2），每个R 1独立地是H，烷基或取代的烷基; R2是H，烷基或取代的烷基; k为1或2，条件是当k为2时，一个R2不为H; R3是H，烷基或氨基保护基; W 0是式（3）; W是CH或N; W 1是O，N（R 4），N（C（O）R 4）或S; W 2是O，N（R 4），N（C（O）R 4）或S; R是H，F，Cl，Br，I，烷基，取代的烷基或炔基; 烷基是具有1-6个碳原子的直链和支链部分。

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