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1. 发明申请

WO2007076021A9 INTRAGASTRIC BAG FOR TREATING OBESITY 审中-公开
标题翻译：肠内用于治疗肥胖的袋子
公开(公告)号：WO2007076021A9
公开(公告)日：2008-01-17
申请号：PCT/US2006049045
申请日：2006-12-21
申请人： WILSON COOK MEDICAL INC , HALLER FREDERICK B , KARPIEL JOHN A , O'SULLIVAN DONAGH , RUCKER BRIAN K , SOETERMANS MAX , VOORHEES WILLIAM D III
发明人： HALLER FREDERICK B , KARPIEL JOHN A , O'SULLIVAN DONAGH , RUCKER BRIAN K , SOETERMANS MAX , VOORHEES WILLIAM D III
IPC分类号： A61F5/00
CPC分类号： A61F5/0003 , A61F5/0036
摘要： An apparatus and method comprising at least one intragastric member made of a digestive-resistant or substantially indigestible material that is introduced into a bag located in the gastric lumen of a mammal for the treatment of obesity. One or more intragastric members are loaded into a delivery tube in partially compacted first configuration and delivered to an overtube. The overtu includes a proximal end, a distal end and a lumen configured to receive the intragastric members in the first configuration for delivery to the bag located in t gastric lumen wherein the intragastric member is expanded to a second configuration. The apparatus further comprises a constraining element engaged with the bag to secure the intragastric member upon delivery into the gastric lumen.
摘要翻译：一种装置和方法，包括至少一个由消化不良或基本上难消化的材料制成的胃内部件，所述胃内部件被引入位于哺乳动物的胃腔中的用于治疗肥胖症的袋中。将一个或多个胃内部件以部分压实的第一构型装载到输送管中并且输送到外套管。该超支包括近端，远端和构造成接收处于第一构型中的胃内部件的腔，用于输送到位于胃内腔中的囊，其中胃内部件膨胀至第二构型。所述装置还包括与所述袋接合的约束元件，以在输送到胃管腔中时固定胃内部件。

2. 发明申请

WO1995006487A2 INTRAVASCULAR MEDICAL DEVICE 审中-公开
标题翻译：血管内科医疗器械
公开(公告)号：WO1995006487A2
公开(公告)日：1995-03-09
申请号：PCT/US1994012128
申请日：1994-08-29
申请人： MED INSTITUTE, INC. , FEARNOT, Neal, E. , RAGHEB, Anthony, O. , VOORHEES, William, D., III
发明人： MED INSTITUTE, INC.
IPC分类号： A61L33/00
CPC分类号： A61L31/16 , A61L29/16 , A61L33/0011 , A61L33/0047 , A61L2300/254 , A61L2300/42
摘要： An intravascular medical device (10) having a structure (11) shaped and sized for introduction into the vascular system of a patient, the structure having biologically inert properties and a thrombolytic agent (13) or an antithrombogenic agent (14). The thrombolytic agent advantageously dissolves or breaks up the formation of thrombus on the surface of the structure when placed in the vascular system of a patient. The antithrombogenic agent inhibits the formation of thrombus on the surface of the medical device. The structure also includes a biologically inert material (15) that forms either at least part of the base material of the device or a coating material (22) on the base material. The thrombolytic agent and/or antithrombogenic agent are homogeneously combined with the base and/or coating material.
摘要翻译：一种血管内医疗装置（10），其具有形状和尺寸用于引入患者血管系统的结构（11），所述结构具有生物惰性特性和溶血栓剂（13）或抗血栓形成剂（14）。当置于患者的血管系统中时，溶栓剂有利地溶解或破坏结构表面上形成血栓。抗血栓形成剂抑制医疗装置表面上的血栓形成。该结构还包括生物惰性材料（15），其形成装置的至少一部分基材或基材上的涂层材料（22）。溶血栓剂和/或抗血栓形成剂与基底和/或涂层材料均匀组合。

3. 发明申请

WO9506487A3 INTRAVASCULAR MEDICAL DEVICE 审中-公开
标题翻译：血管内科医疗器械
公开(公告)号：WO9506487A3
公开(公告)日：1995-04-06
申请号：PCT/US9412128
申请日：1994-08-29
申请人： MED INST INC , FEARNOT NEAL E , RAGHEB ANTHONY O , VOORHEES WILLIAM D III
发明人： FEARNOT NEAL E , RAGHEB ANTHONY O , VOORHEES WILLIAM D III
IPC分类号： A61L27/00 , A61L29/00 , A61L29/16 , A61L31/16 , A61L33/00
CPC分类号： A61L31/16 , A61L29/16 , A61L33/0011 , A61L33/0047 , A61L2300/254 , A61L2300/42
摘要： An intravascular medical device (10) having a structure (11) shaped and sized for introduction into the vascular system of a patient, the structure having biologically inert properties and a thrombolytic agent (13) or an antithrombogenic agent (14). The thrombolytic agent advantageously dissolves or breaks up the formation of thrombus on the surface of the structure when placed in the vascular system of a patient. The antithrombogenic agent inhibits the formation of thrombus on the surface of the medical device. The structure also includes a biologically inert material (15) that forms either at least part of the base material of the device or a coating material (22) on the base material. The thrombolytic agent and/or antithrombogenic agent are homogeneously combined with the base and/or coating material.

4. 发明申请

WO2008019116A3 IMPLANTABLE MEDICAL DEVICE WITH PARTICULATE COATING 审中-公开
公开(公告)号：WO2008019116A3
公开(公告)日：2008-02-14
申请号：PCT/US2007/017431
申请日：2007-08-03
申请人： MED INSTITUTE, INC. , GREWE, David, D. , VOORHEES, William, D. , RAGHEB, Anthony, O.
发明人： GREWE, David, D. , VOORHEES, William, D. , RAGHEB, Anthony, O.
IPC分类号： A61L31/08 , A61L27/28
摘要： Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. A medical device can include a frame with a vessel-engaging region on at least a portion of the medical device. The vessel- engaging region may be a particulate coating configured and adapted to engage the interior wall of a body vessel or to attach a material, such as a valve leaflet or graft material, to the frame. Methods of making an implantable medical device and methods of treating a subject are also disclosed.

5. 发明申请

WO2008019116A2 IMPLANTABLE MEDICAL DEVICE WITH PARTICULATE COATING 审中-公开
标题翻译：具有颗粒涂层的可植入医疗装置
公开(公告)号：WO2008019116A2
公开(公告)日：2008-02-14
申请号：PCT/US2007017431
申请日：2007-08-03
申请人： MED INST INC , GREWE DAVID D , VOORHEES WILLIAM D , RAGHEB ANTHONY O
发明人： GREWE DAVID D , VOORHEES WILLIAM D , RAGHEB ANTHONY O
IPC分类号： A61L31/08
CPC分类号： A61L31/082
摘要： Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. A medical device can include a frame with a vessel-engaging region on at least a portion of the medical device. The vessel- engaging region may be a particulate coating configured and adapted to engage the interior wall of a body vessel or to attach a material, such as a valve leaflet or graft material, to the frame. Methods of making an implantable medical device and methods of treating a subject are also disclosed.
摘要翻译：提供了用于植入体内的医疗装置及其使用和制造方法。医疗装置可以包括在医疗装置的至少一部分上具有容器接合区域的框架。容器接合区域可以是构造并适于接合身体容器的内壁或者将诸如瓣叶或移植材料的材料附接到框架的颗粒涂层。还公开了制造可植入医疗装置的方法和治疗受试者的方法。

6. 发明申请

WO2007142935B1 ARTIFICIAL VALVE PROSTHESIS 审中-公开
标题翻译：人造阀门
公开(公告)号：WO2007142935B1
公开(公告)日：2008-02-14
申请号：PCT/US2007012684
申请日：2007-05-30
申请人： COOK INC , MED INST INC , FEARNOT NEIL E , LEEWOOD ALAN R , PAUL RAM H , ROEDER BLAYNE A , VOORHEES WILLIAM D
发明人： FEARNOT NEIL E , LEEWOOD ALAN R , PAUL RAM H , ROEDER BLAYNE A , VOORHEES WILLIAM D
IPC分类号： A61F2/06 , A61F2/24
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/005 , A61F2220/0058
摘要： A self-expanding or otherwise expandable artificial valve prostheses for deployment within a body passageway, such as a vessel or duct of a patient. The valve prostheses include a support structure having an outer frame, a supporting member and a valve leaflet. The portion of the valve leaflet is supported by the supporting member and is positioned away from the wall of the body passageway when the device is deployed within the body passageway.
摘要翻译：用于展开在身体通道（例如患者的血管或导管）内的自膨胀或其他可膨胀的人造瓣膜假体。瓣膜假体包括具有外框架，支撑构件和瓣膜小叶的支撑结构。瓣膜小叶的部分由支撑构件支撑，并且当装置展开在身体通道内时，其被定位成远离身体通道的壁。

7. 发明申请

WO2007142935A1 ARTIFICIAL VALVE PROSTHESIS 审中-公开
标题翻译：人造阀门
公开(公告)号：WO2007142935A1
公开(公告)日：2007-12-13
申请号：PCT/US2007/012684
申请日：2007-05-30
申请人： COOK INCORPORATED , MED INSTITUTE, INCORPORATED , FEARNOT, Neil, E. , LEEWOOD, Alan, R. , PAUL, Ram, H. , ROEDER, Blayne, A. , VOORHEES, William, D.
发明人： FEARNOT, Neil, E. , LEEWOOD, Alan, R. , PAUL, Ram, H. , ROEDER, Blayne, A. , VOORHEES, William, D.
IPC分类号： A61F2/06 , A61F2/24
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/005 , A61F2220/0058
摘要： A self-expanding or otherwise expandable artificial valve prostheses for deployment within a body passageway, such as a vessel or duct of a patient. The valve prostheses include a support structure having an outer frame, a supporting member and a valve leaflet. The portion of the valve leaflet is supported by the supporting member and is positioned away from the wall of the body passageway when the device is deployed within the body passageway.
摘要翻译：用于展开在身体通道（例如患者的血管或导管）内的自膨胀或其他可膨胀的人造瓣膜假体。瓣膜假体包括具有外框架，支撑构件和瓣膜小叶的支撑结构。瓣膜小叶的部分由支撑构件支撑，并且当装置展开在身体通道内时，其被定位成远离身体通道的壁。

8. 发明申请

WO2007076021A3 INTRAGASTRIC BAG FOR TREATING OBESITY 审中-公开
公开(公告)号：WO2007076021A3
公开(公告)日：2007-07-05
申请号：PCT/US2006/049045
申请日：2006-12-21
申请人： WILSON-COOK MEDICAL INC. , HALLER, Frederick, B. , KARPIEL, John, A. , O'SULLIVAN, Donagh , RUCKER, Brian, K. , SOETERMANS, Max , VOORHEES, William, D., III
发明人： HALLER, Frederick, B. , KARPIEL, John, A. , O'SULLIVAN, Donagh , RUCKER, Brian, K. , SOETERMANS, Max , VOORHEES, William, D., III
IPC分类号： A61F5/00
摘要： An apparatus and method comprising at least one intragastric member made of a digestive-resistant or substantially indigestible material that is introduced into a bag located in the gastric lumen of a mammal for the treatment of obesity. One or more intragastric members are loaded into a delivery tube in partially compacted first configuration and delivered to an overtube. The overtu includes a proximal end, a distal end and a lumen configured to receive the intragastric members in the first configuration for delivery to the bag located in t gastric lumen wherein the intragastric member is expanded to a second configuration. The apparatus further comprises a constraining element engaged with the bag to secure the intragastric member upon delivery into the gastric lumen.

9. 发明申请

WO2007076021A2 INTRAGASTRIC BAG FOR TREATING OBESITY 审中-公开
标题翻译：胃肠袋治疗肥胖症
公开(公告)号：WO2007076021A2
公开(公告)日：2007-07-05
申请号：PCT/US2006049045
申请日：2006-12-21
申请人： WILSON COOK MEDICAL INC , HALLER FREDERICK B , KARPIEL JOHN A , O'SULLIVAN DONAGH , RUCKER BRIAN K , SOETERMANS MAX , VOORHEES WILLIAM D III
发明人： HALLER FREDERICK B , KARPIEL JOHN A , O'SULLIVAN DONAGH , RUCKER BRIAN K , SOETERMANS MAX , VOORHEES WILLIAM D III
IPC分类号： A61F5/00
CPC分类号： A61F5/0003 , A61F5/0036
摘要： An apparatus and method comprising at least one intragastric member made of a digestive-resistant or substantially indigestible material that is introduced into a bag located in the gastric lumen of a mammal for the treatment of obesity. One or more intragastric members are loaded into a delivery tube in partially compacted first configuration and delivered to an overtube. The overtu includes a proximal end, a distal end and a lumen configured to receive the intragastric members in the first configuration for delivery to the bag located in t gastric lumen wherein the intragastric member is expanded to a second configuration. The apparatus further comprises a constraining element engaged with the bag to secure the intragastric member upon delivery into the gastric lumen.
摘要翻译：一种装置和方法，该装置和方法包括至少一个由抗消化或基本不消化的材料制成的胃内部件，该部件被引入位于哺乳动物的胃腔中的袋子中用于治疗肥胖症。将一个或多个胃内构件以部分压实的第一构造加载到输送管中并输送到外套管。所述覆盖物包括近端，远端和内腔，所述内腔构造成接收处于所述第一构型的所述胃内构件以递送至位于所述胃腔内的所述袋，其中所述胃内构件膨胀至第二构型。该设备还包括约束元件，该约束元件与袋接合以在输送到胃腔内时固定胃内构件。

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