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1. 发明申请

WO2021045632A1 CANCER VACCINE 审中-公开
公开(公告)号：WO2021045632A1
公开(公告)日：2021-03-11
申请号：PCT/NZ2020/050099
申请日：2020-09-03
申请人： VICTORIA LINK LTD
发明人： HERMANS, Ian Francis , PAINTER, Gavin Frank , PRASIT, Kef Kawin
IPC分类号： A61K47/54 , A61K31/7125 , A61P35/00
摘要： The invention relates to a combination of a TLR-9 agonist and a conjugate of Formula (I) or pharmaceutically acceptable salt thereof. (Formula (I))

2. 发明申请

WO2015118481A1 TRANSIENT GRATING TIME RESOLVED LUMINESCENCE MEASUREMENTS 审中-公开
标题翻译：瞬态光刻时间分辨光度测量
公开(公告)号：WO2015118481A1
公开(公告)日：2015-08-13
申请号：PCT/IB2015/050884
申请日：2015-02-05
申请人： VICTORIA LINK LTD
发明人： HODGKISS, Justin M. , CHEN, Kai
IPC分类号： G01B9/02 , G01B11/00 , G01J3/18
CPC分类号： G01J1/4228 , G01J3/0232 , G01J3/2889 , G01J3/4406 , G01J2003/4424 , G01N21/636 , G01N21/6408 , G01N21/65 , G01N2201/061 , G01N2201/0696
摘要： A transient grating (TG) is used as an optical gating element with sub-picosecond time resolution for luminescence measurements from a photo-detector array. The transient grating is formed in a gate medium by one or more pulsed gate beams. For photoluminescence measurements such as photoluminescence spectroscopy or imaging, a source is excited by a pulsed excitation beam, and the pulsed gate beams are synchronized to the pulsed excitation beam with an adjustable delay between the excitation of the source and the formation of the TG. Moreover, a source or its spectra can be imaged at two different regions of the photo-detector array at two different times spaced in time by a selected duration of time with sub-picosecond resolution over a range of a nanosecond or more. A beam from the source is deflected to the different regions by changing the frequency or geometry of the pulsed gate beams.
摘要翻译：瞬态光栅（TG）被用作具有亚皮秒时间分辨率的来自光电检测器阵列的发光测量的光学门控元件。瞬态光栅通过一个或多个脉冲栅极波束在栅极介质中形成。对于诸如光致发光光谱或成像的光致发光测量，源通过脉冲激发光束激发，并且脉冲栅极光束与脉冲激发光束同步，在源的激发和TG的形成之间具有可调节的延迟。此外，源或其光谱可以在光检测器阵列的两个不同的区域以两分之一的时间在一个纳秒或更多的范围内以亚皮秒分辨率的时间间隔被成像。来自源极的光束通过改变脉冲栅极的频率或几何形状而偏转到不同的区域。

3. 发明申请

WO2012018264A3 SYSTEMS, METHODS AND COMPOSITIONS FOR THE PRODUCTION OF SILICON NITRIDE NANOSTRUCTURES 审中-公开
标题翻译：用于生产氮化硅纳米结构的系统，方法和组合物
公开(公告)号：WO2012018264A3
公开(公告)日：2012-03-29
申请号：PCT/NZ2011000149
申请日：2011-08-02
申请人： CRL ENERGY LTD , VICTORIA LINK LTD , SPENCER JOHN , MCCURDY MURRAY , DOUGHERTY TROY , BAKALAR JOAN
发明人： SPENCER JOHN , MCCURDY MURRAY , DOUGHERTY TROY , CLEMENS ANTHONY HEATHCOTE
IPC分类号： C01B21/068 , B82Y30/00 , B82Y40/00
CPC分类号： C01B21/068 , B82Y30/00 , C01B21/0685 , C01P2004/16
摘要： Systems, methods and compositions for the production of silicon nitride nanostructures are herein disclosed. In at least one embodiment, a carbon feedstock is preprocessed, combined with a silicon feedstock and annealed in the presence of a nitrogen containing compound to produce a silicon nitride nanostructure.
摘要翻译：本文公开了用于生产氮化硅纳米结构的系统，方法和组合物。在至少一个实施方案中，碳原料被预处理，与硅原料结合并在含氮化合物存在下退火以产生氮化硅纳米结构。

4. 发明申请

WO2008041866A3 NMR SPECTRA EXTRACTION METHOD 审中-公开
标题翻译： NMR谱提取方法
公开(公告)号：WO2008041866A3
公开(公告)日：2008-05-22
申请号：PCT/NZ2007000287
申请日：2007-10-03
申请人： VICTORIA LINK LTD , CALLAGHAN PAUL TERENCE , HALSE MEGHAN EILEEN
发明人： CALLAGHAN PAUL TERENCE , HALSE MEGHAN EILEEN
IPC分类号： G01R33/38 , G01R33/44 , G01R33/48 , G01R33/56
CPC分类号： G01R33/4625 , G01R33/445 , G01R33/485 , G01R33/5615 , G01R33/5616 , G01R33/56563 , G01R33/58
摘要： The invention provides a method of extracting NMR spectra from a sample under investigation. The method comprises subjecting both the sample under investigation and a reference sample to an inhomogeneous static magnetic field, one or more RF pulses, and one or more applied magnetic field gradients to acquire NMR sub-sample signals from two or more regions of the sample under investigation and the reference sample respectively; deconvolving the NMR sub-sample signals acquired from regions of the sample under investigation with the NMR sub-sample signals acquired from corresponding regions of the reference sample to produce a deconvolved signal for each region; and summing together the deconvolved signals for each region to obtain the NMR spectra of the sample under investigation. The invention further provides related methods and nuclear magnetic resonance spectra extraction systems.
摘要翻译：本发明提供从被研究样品中提取NMR光谱的方法。该方法包括将所研究的样品和参考样品两者都进行不均匀的静磁场，一个或多个RF脉冲以及一个或多个施加的磁场梯度，以从样品的两个或更多个区域获取NMR子样本信号调查和参考样本分别; 使用从参考样本的相应区域获取的NMR子采样信号对从研究样品的区域获取的NMR子采样信号进行解卷积，以产生每个区域的去卷积信号; 并将每个区域的去卷积信号相加，以获得正在研究的样品的NMR光谱。本发明还提供了相关方法和核磁共振谱提取系统。

5. 发明申请

WO2022124915A1 MAMMALIAN ATTRACTANT 审中-公开
公开(公告)号：WO2022124915A1
公开(公告)日：2022-06-16
申请号：PCT/NZ2021/050217
申请日：2021-12-09
申请人： LANDCARE RESEARCH NEW ZEALAND LIMITED [NZ]/[NZ] , VICTORIA LINK LTD [NZ]/[NZ]
发明人： GARVEY, Patrick , JACKSON, Michael David , LINKLATER, Wayne Leslie
IPC分类号： A01N63/10 , A01N27/00 , A01N35/02 , A01N31/02 , A01N25/04 , A01P9/00
摘要： The invention relates to mammalian attractants and to the use of such attractants in baits and traps for killing, capturing and/or monitoring mammalian targets; in particular mustelids.

6. 发明申请

WO2019171333A1 TREATMENT OF DEMYELINATING DISEASES 审中-公开
公开(公告)号：WO2019171333A1
公开(公告)日：2019-09-12
申请号：PCT/IB2019/051870
申请日：2019-03-07
申请人： VICTORIA LINK LTD , UNIVERSITY OF KANSAS
发明人： KIVELL, Bronwyn Maree , LA FLAMME, Anne Camille , PRISINZANO, Thomas Edward
IPC分类号： A61K31/485 , A61P25/00 , A61P25/02 , A61P25/28
摘要： The present invention relates generally to methods of using nalfurafine for treating and/or preventing demyelinating disease in a subject, and in particular for treating and/or preventing multiple sclerosis (MS). Also disclosed is nalfurafine for use in treating and/or preventing MS as well as pharmaceutical compositions and unit dosage forms comprising nalfurafine for use for treating and/or preventing demyelinating disease in a subject, and in particular for treating and/or preventing MS.

7. 发明申请

WO2014038963A9 DENDRIMER SCAFFOLDS FOR PHARMACEUTICAL USE 审中-公开
标题翻译：用于药物使用的DENDRIMER SCAFFOLDS
公开(公告)号：WO2014038963A9
公开(公告)日：2014-09-18
申请号：PCT/NZ2013000161
申请日：2013-09-05
申请人： VICTORIA LINK LTD
发明人： RENDLE PHILLIP MARTIN , TOMS STEVEN
IPC分类号： C07C235/74 , A61K47/30 , C07C231/02
CPC分类号： C07H15/04 , A61K47/32 , A61K47/48192 , A61K47/59 , A61K49/0021 , A61K49/0054 , A61K49/124 , C07C229/06 , C07C229/10 , C07C229/38 , C07C233/18 , C07C237/08
摘要： This invention relates to certain dendrimer compounds. In particular, this invention relates to novel dendrimer compounds that can be elaborated to give increasingly large and complex compounds. These elaborated compounds can be attached to, or can encapsulate within, active agent(s) so as to beneficially modify the characteristics of that active agent. Alternatively, the elaborated compounds can themselves be beneficially modified into therapeutic agents by the attachment of inactive agents.
摘要翻译：本发明涉及某些树枝状大分子化合物。具体而言，本发明涉及可被精制以产生越来越大且复杂的化合物的新颖树状聚合物化合物。这些精心制作的化合物可以附着于或可以封装在活性剂内，以有益地改变活性剂的特性。或者，精制的化合物本身可以通过附着非活性剂而有利地修饰成治疗剂。

8. 发明申请

WO2019088855A1 BRANCHED TREHALOSE GLYCOLIPIDS 审中-公开
公开(公告)号：WO2019088855A1
公开(公告)日：2019-05-09
申请号：PCT/NZ2018/050157
申请日：2018-11-02
申请人： VICTORIA LINK LTD , OSAKA UNIVERSITY
发明人： STOCKER, Bridget Louise , TIMMER, Mattheus Simon Maria , YAMASAKI, Sho , CHISNALL, Jessica Helen
IPC分类号： C07H13/06 , A61K31/7028
摘要： The invention relates to branched trehalose glycolipids of Formula (I) and their uses. These compounds are potent Mincle agonists and Th1-stimulating vaccine adjuvants.

9. 发明申请

WO2019088854A1 BRARTEMICIN ANALOGUES 审中-公开
公开(公告)号：WO2019088854A1
公开(公告)日：2019-05-09
申请号：PCT/NZ2018/050156
申请日：2018-11-02
申请人： VICTORIA LINK LTD , OSAKA UNIVERSITY
发明人： FOSTER, Amy Jane , STOCKER, Bridget Louise , TIMMER, Mattheus Simon Maria , YAMASAKI, Sho
IPC分类号： C07H13/08 , C07H13/04 , A61K31/7034 , A61P37/04
摘要： The invention relates to brartemicin analogues of Formula (IV) and their uses. These compounds are potent Mincle agonists and Th1-stimulating vaccine adjuvants.

10. 发明申请

WO2017089960A1 MICROSTRUCTURED SURFACES FOR ENHANCED PHASE CHANGE HEAT TRANSFER 审中-公开
标题翻译：用于增强相变热传递的微结构表面
公开(公告)号：WO2017089960A1
公开(公告)日：2017-06-01
申请号：PCT/IB2016/057042
申请日：2016-11-22
申请人： VICTORIA LINK LTD
发明人： GOUWS, Gideon J.
IPC分类号： F28F13/18 , B22F3/22 , B22F3/11
CPC分类号： B22F3/11 , B22F3/22 , B22F7/04 , C23C24/08 , F28D15/0233 , F28D15/046 , F28F13/187 , F28F2255/18
摘要： A thermally conductive substrate has formed thereon a microstructured surface layer of sintered metal surfaced nanoparticles providing a hierarchical void structure for facilitating two-phase heat transfer. The hierarchical void structure includes small voids smaller than one micron, large voids larger than the small voids; and elongated intermediate size voids forming channels between walls of the particles. The microstructure can be made by making a suspension of the nanoparticles solvent comprising a binder material, coating the substrate with the suspension to form a surface layer on the substrate, and then cooling the coated substrate below a freezing point of the solvent to induce segregation between the particles and the frozen solvent, and then removing the frozen solvent from the surface layer, and then heating the coated substrate to sinter the particles together.
摘要翻译：导热基底上形成有烧结金属表面纳米颗粒的微结构化表面层，其提供用于促进两相热传递的分层空隙结构。分层空隙结构包括小于1微米的小空隙，大空隙大于小空隙; 和细长的中间尺寸空隙，形成颗粒壁之间的通道。可以通过制备包含粘合剂材料的纳米颗粒溶剂的悬浮液，用悬浮液涂覆基底以在基底上形成表面层，然后将涂覆的基底冷却至溶剂的冰点以下以诱导分离颗粒和冷冻溶剂，然后从表面层中除去冷冻溶剂，然后加热涂覆的基材以将颗粒一起烧结。

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