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1. 发明申请

WO2005077276A2 SYSTEM AND METHOD FOR URODYNAMIC EVALUATION UTILIZING MICRO-ELECTRONIC MECHANICAL SYSTEM 审中-公开
标题翻译：利用微电子机械系统进行动力学评估的系统与方法
公开(公告)号：WO2005077276A2
公开(公告)日：2005-08-25
申请号：PCT/US2005/002148
申请日：2005-01-26
申请人： ETHICON, INC. , TRACEY, Michael, R. , DI UBALDI, Anthony
发明人： TRACEY, Michael, R. , DI UBALDI, Anthony
IPC分类号： A61B5/20
CPC分类号： A61N1/36017 , A61B5/14507 , A61B5/202 , A61B5/205 , A61B5/208 , A61B5/6874 , A61B2562/028 , A61N1/36007
摘要： An implantable urodynamic system is provided one embodiment of which includes a power source, at least one sensor for sensing at least one physiological property, a data transmission device for transmitting data representing the at least one sensed physiological property to an exterior of the patient's bladder, and a collapsible housing containing the power source and the at least one sensor therein. The collapsible housing has a collapsed configuration sized for insertion through the patient's urethra and into the patient's bladder, and an expanded configuration sized to remain within the bladder, but be unable to pass from the bladder into the urethra.
摘要翻译：可植入尿动力系统的一个实施例包括电源，用于感测至少一个生理特性的至少一个传感器，用于将表示至少一个感测到的生理特性的数据发送到患者膀胱的外部的数据传输装置，以及容纳所述电源和所述至少一个传感器的可折叠壳体。可折叠壳体具有尺寸适于插入穿过患者尿道并进入患者膀胱的折叠构造，以及尺寸适于保持在膀胱内但不能从膀胱穿入尿道的扩张构型。

2. 发明申请

WO2008070817A1 SYSTEM AND METHOD FOR URODYNAMIC EVALUATION UTILIZING MICRO ELECTRO-MECHANICAL SYSTEM TECHNOLOGY 审中-公开
标题翻译：利用微机电系统技术进行动力学评估的系统与方法
公开(公告)号：WO2008070817A1
公开(公告)日：2008-06-12
申请号：PCT/US2007/086710
申请日：2007-12-07
申请人： ETHICON, INC. , TRACEY, Michael, R. , DIUBALDI, Anthony , WAHLGREN, Stephen, B. , BARE, Rex, O. , SARGENT, Bradley, J.
发明人： TRACEY, Michael, R. , DIUBALDI, Anthony , WAHLGREN, Stephen, B. , BARE, Rex, O. , SARGENT, Bradley, J.
IPC分类号： A61B5/00
CPC分类号： A61B5/14507 , A61B5/0031 , A61B5/205 , A61B5/208 , A61B5/6874 , A61B2562/028
摘要： An implantable urodynamic system includes an implantable first device deployable in a patient s bladder, an implantable second device deployable in a patient s vaginal canal, and a data acquisition and analysis module or processing unit external to the body of the patient. The first device includes a magnet and an inductive coil, and the second device includes a magnet, an inductive coil and a battery. When deployed in the patient s body, the magnets maintain the devices in close proximity to one another to effect an inductive coupling between the coils so that the first device is powered by the battery of the second device. The urodynamic system facilitates measurement, collection, and wireless transmission of real-time, or near real-time, data (bladder pressure, abdominal pressure, and temperature) from an ambulatory patient.
摘要翻译：可植入尿动力系统包括可部署在患者膀胱内的可植入第一装置，可植入患者阴道内的可植入第二装置，以及在患者身体外部的数据采集和分析模块或处理单元。第一装置包括磁体和感应线圈，并且第二装置包括磁体，感应线圈和电池。当部署在患者体内时，磁体将装置保持在彼此靠近的位置，以实现线圈之间的电感耦合，使得第一装置由第二装置的电池供电。尿动力系统便于来自流动患者的实时或近实时数据（膀胱压力，腹压和温度）的测量，收集和无线传输。

3. 发明申请

WO2006132810A3 SYSTEM AND METHOD FOR NERVE STIMULATION 审中-公开
标题翻译：神经刺激的系统和方法
公开(公告)号：WO2006132810A3
公开(公告)日：2007-02-22
申请号：PCT/US2006020192
申请日：2006-05-24
申请人： ETHICON INC , TRACEY MICHAEL R , DIUBALDI ANTHONY
发明人： TRACEY MICHAEL R , DIUBALDI ANTHONY
IPC分类号： A61N1/36 , A61B5/03 , A61B5/20
CPC分类号： A61N1/36007 , A61B5/20 , A61B5/202 , A61B5/205 , A61B5/6874 , A61B2562/028 , A61N1/0492 , A61N1/0514 , A61N1/0521 , A61N1/36017 , A61N1/36021
摘要： A system and method for stimulating a nerve, wherein the system includes a first waveform generator adapted to generate a first waveform having a frequency capable of stimulating a predetermined nerve of the mammal, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the mammal, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the mammal, and adapted to apply the modulated waveform thereto.
摘要翻译：一种用于刺激神经的系统和方法，其中所述系统包括适于产生具有能够刺激哺乳动物的预定神经的频率的第一波形的第一波形发生器，适于生成具有频率能力的载波波形的第二波形发生器通过哺乳动物的组织的调制装置，电耦合到第一和第二波形发生器并适于调制第一和载波波形以产生调制波形的调制装置，以及电耦合到调制装置并基本上邻近皮肤定位的电极并且适于将调制波形应用于其。

4. 发明申请

WO2010111506A1 PIEZOELECTRIC STIMULATION DEVICE 审中-公开
标题翻译：压电刺激装置
公开(公告)号：WO2010111506A1
公开(公告)日：2010-09-30
申请号：PCT/US2010/028690
申请日：2010-03-25
申请人： ETHICON, INC. , DIUBALDI, Anthony , WAHLGREN, Stephen , TRACEY, Michael, R.
发明人： DIUBALDI, Anthony , WAHLGREN, Stephen , TRACEY, Michael, R.
IPC分类号： A61N1/32
CPC分类号： A61N1/32 , A61B5/205 , A61B5/6874 , A61B2562/028 , A61H23/0245 , A61H2201/5005 , A61N1/36007 , A61N1/36014 , A61N1/36017 , A61N1/3787
摘要： A method for stimulating a predetermined body part such as a nerve using a stimulation device including an external non-implantable transmitting device powered by a power source and generating an electrical waveform signal. A surface electrode applies the generated electrical waveform signal transcutaneously. An implantable piezoelectric element receives the applied electrical waveform signal generated transcutaneously and, in turn, causes mechanical deformation resulting in mechanical vibration of the implantable piezoelectric element sufficient to stimulate the predetermined body part. The electrical waveform signal may be either a high frequency continuous waveform or high frequency burst packets.
摘要翻译：一种使用包括由电源供电的外部非植入式发送装置的刺激装置来刺激诸如神经的预定身体部位并产生电波形信号的方法。表面电极经常地施加所生成的电波形信号。可植入式压电元件接收经过生成的施加的电波形信号，从而导致机械变形，导致可植入式压电元件的机械振动足以刺激预定的身体部位。电波形信号可以是高频连续波形或高频突发分组。

5. 发明申请

WO2010080222A1 OPTIMIZING STIMULATION THERAPY OF AN EXTERNAL STIMULATING DEVICE BASED ON FIRING OF ACTION POTENTIAL IN TARGET NERVE 审中-公开
标题翻译：基于靶向动作电位的外部刺激装置的优化刺激治疗
公开(公告)号：WO2010080222A1
公开(公告)日：2010-07-15
申请号：PCT/US2009/065327
申请日：2009-11-20
申请人： ETHICON, INC. , WAHLGREN, Stephen, S. , TRACEY, Michael, R.
发明人： WAHLGREN, Stephen, S. , TRACEY, Michael, R.
IPC分类号： A61N1/08 , A61N1/36 , A61N1/05 , A61B5/04
CPC分类号： A61N1/36017 , A61B5/04001 , A61B5/04005 , A61B5/4041 , A61B5/6846 , A61B2560/0276 , A61N1/08
摘要： A method and system for optimizing stimulation therapy of an external stimulating device. The stimulating signal for stimulation of a target nerve is produced using the external stimulating device. A magnetic field is induced in an implanted transmitting coil disposed proximate the target nerve when the action potential is fired along an axon of the target nerve. In turn, a feedback signal is generated in a receiving coil associated with the external stimulating device based on whether the target nerve fires an action potential. Stimulating signal parameters of the stimulating signal are adjusted based on the feedback signal.
摘要翻译：一种用于优化外部刺激装置的刺激治疗的方法和系统。使用外部刺激装置产生用于刺激目标神经的刺激信号。当沿靶神经的轴突发射动作电位时，在靠近目标神经设置的植入的发射线圈中诱发磁场。反过来，基于目标神经是否触发动作电位，在与外部刺激装置相关联的接收线圈中产生反馈信号。基于反馈信号调整刺激信号的刺激信号参数。

6. 发明申请

WO2009079270A1 DERMATOME STIMULATION DEVICES AND METHODS 审中-公开
标题翻译： DERMATOME刺激装置和方法
公开(公告)号：WO2009079270A1
公开(公告)日：2009-06-25
申请号：PCT/US2008/086031
申请日：2008-12-09
申请人： ETHICON, INC. , WAHLGREN, Stephen B. , TRACEY, Michael R. , DIUBALDI, Anthony
发明人： WAHLGREN, Stephen B. , TRACEY, Michael R. , DIUBALDI, Anthony
IPC分类号： A61N1/36
CPC分类号： A61N1/0456 , A61N1/0452 , A61N1/0492 , A61N1/36007 , A61N1/36014 , A61N1/36017 , A61N1/36171
摘要： A nerve stimulation device includes a first waveform generator adapted to generate a first waveform having a first frequency capable of stimulating nerves within a dermatome, a second waveform generator adapted to generate a first carrier waveform having a second frequency capable of passing through tissue of a mammal, and a third waveform generator adapted to generate a second carrier waveform having a third frequency different than the second frequency and being capable of passing through the tissue of the mammal. The device includes a modulator electrically coupled to the first, second and third waveform generators and adapted to modulate the first waveform, the first carrier waveform, and the second carrier waveform to generate a modulated signal package capable of stimulating the nerves at different depths within the dermatome. The device also has an electrode electrically coupled to the modulator for applying the modulated waveform to the dermatomic region.
摘要翻译：神经刺激装置包括：第一波形发生器，其适于产生具有能够刺激皮肤内的神经的第一频率的第一波形;适于生成具有能够穿过哺乳动物的组织的第二频率的第一载波波形的第二波形发生器以及适于生成具有与第二频率不同的第三频率并且能够通过哺乳动物的组织的第二载波波形的第三波形发生器。该装置包括电耦合到第一，第二和第三波形发生器并且适于调制第一波形，第一载波波形和第二载波波形的调制器，以产生调制信号包，该调制信号包能够在不同深度内刺激神经皮。器件还具有电耦合到调制器的电极，用于将调制波形施加到皮肤原始区域。

7. 发明申请

WO2009064641A1 NERVE STIMULATION PATCHES AND METHODS FOR STIMULATING SELECTED NERVES 审中-公开
标题翻译：神经刺激指征和刺激选择性神经的方法
公开(公告)号：WO2009064641A1
公开(公告)日：2009-05-22
申请号：PCT/US2008/082435
申请日：2008-11-05
申请人： ETHICON, INC. , DIUBALDI, Anthony , TRACEY, Michael R. , BARE, Rex O. , SARGENT, Bradley J. , WAHLGREN, Stephen B.
发明人： DIUBALDI, Anthony , TRACEY, Michael R. , BARE, Rex O. , SARGENT, Bradley J. , WAHLGREN, Stephen B.
IPC分类号： A61N1/04 , A61N1/34 , A61N1/375 , A61N1/36
CPC分类号： A61N1/0456 , A61N1/0452 , A61N1/0492 , A61N1/0496 , A61N1/36007 , A61N1/36014 , A61N1/36021 , A61N1/375 , A61N1/3756 , A61N1/3758 , H05K3/281 , H05K2201/2018
摘要： A selective nerve stimulation patch includes a substrate having a top surface and a bottom surface, integrated components overlying the top surface of the substrate and electrically interconnected with one another for generating at least one nerve stimulating signal, electrodes integrated into the substrate and exposed at the bottom surface thereof for applying the at least one nerve stimulating signal to a target nerve, a waterproof, breathable cover overlying the substrate and the integrated components, and a support flange surrounding the substrate and coupling the cover and the substrate together.
摘要翻译：选择性神经刺激贴片包括具有顶表面和底表面的基底，整合的元件覆盖在基底的顶表面上并彼此电互连以产生至少一种神经刺激信号，集成到基底中的电极并暴露于其底表面用于将至少一个神经刺激信号施加到目标神经，覆盖在基底和集成部件上的防水透气盖，以及围绕基底并将盖和基底连接在一起的支撑凸缘。

8. 发明申请

WO2007090047A1 SYSTEM AND METHOD FOR SELECTIVELY STIMULATING DIFFERENT BODY PARTS 审中-公开
标题翻译：选择性刺激不同身体部位的系统和方法
公开(公告)号：WO2007090047A1
公开(公告)日：2007-08-09
申请号：PCT/US2007/061107
申请日：2007-01-26
申请人： ETHICON, INC. , TRACEY, Michael R. , DIUBALDI, Anthony , JOHNS, Douglas B.
发明人： TRACEY, Michael R. , DIUBALDI, Anthony , JOHNS, Douglas B.
IPC分类号： A61N1/05
CPC分类号： A61N1/36017 , A61N1/0492 , A61N1/0551 , A61N1/36003 , A61N1/36007 , A61N1/36014 , A61N1/36021
摘要： Devices and methods are provided for electrically stimulating a predetermined body part of a mammal. The method includes placing at least one electrode in proximity to the mammal's skin, injecting an electrically conductive gel into the body of the mammal so as to form a conductive gel pathway extending at least partially along a distance between the at least one electrode and the predetermined body part, and stimulating the predetermined body part by applying an electrical signal via the electrode that travels, at least in part, through the conductive gel pathway.
摘要翻译：提供了用于电刺激哺乳动物的预定身体部位的装置和方法。该方法包括将至少一个电极放置在哺乳动物的皮肤附近，将导电凝胶注射到哺乳动物的体内，以便形成至少部分地沿着至少一个电极与预定的电极之间的距离延伸的导电凝胶通路并通过经由至少部分地穿过导电凝胶路径行进的电极施加电信号来刺激预定的身体部位。

9. 发明申请

WO2007078531A2 STRESS URINARY INCONTINENCE IMPLANT AND DEVICE FOR DEPLOYING SAME 审中-公开
标题翻译：应力不均匀植入物及其配套装置
公开(公告)号：WO2007078531A2
公开(公告)日：2007-07-12
申请号：PCT/US2006/046478
申请日：2006-12-06
申请人： ETHICON, INC. , TRACEY, Michael R. , BELL, Steve , KNODEL, Bryan
发明人： TRACEY, Michael R. , BELL, Steve , KNODEL, Bryan
IPC分类号： A61F2/00 , A61B17/00
CPC分类号： A61F2/0045 , A61B17/0625 , A61B2017/00805 , A61F2/0036
摘要： A suburethral implant for treating stress urinary incontinence includes a platelike member that is curved in transverse cross-section, and a pair of spaced apart arms having hooked ends or barbs that extend from the plate-like member. A device for deploying the suburethral implant includes a vaginal probe including an exit port and a urethra locator probe that is spaced apart from and overlies the vaginal probe. An introducer assembly is extendable through the exit port on the vaginal probe, and has a distal end on which is removably mounted the suburethral implant. The introducer assembly extends through the exit port to pierce the vaginal wall in order to position the suburethral implant in proximity to the patient's urethra. The hooked ends or barbs on the arms of the suburethral implant engage the tissue surrounding the patient's urethra and are affixed thereto during deployment of the implant.
摘要翻译：用于治疗压力性尿失禁的尿道植入物包括在横截面上弯曲的板状构件，以及一对间隔开的臂，其具有从板状构件延伸的钩端或倒钩。用于部署尿道尿道植入物的装置包括阴道探针，其包括与阴道探针间隔开并覆盖在阴道探针上的出口和尿道定位器探针。导引器组件可以通过阴道探针上的出口延伸，并具有远端，可移除地安装在尿道植入物上。导引器组件延伸穿过出口以刺穿阴道壁，以将尿道植入物定位在患者的尿道附近。在尿道植入物的手臂上的钩状末端或倒钩与患者尿道周围的组织接合，并在植入物展开过程中固定到其上。

10. 发明申请

WO2011119951A1 PIEZOELECTRIC STIMULATION DEVICE 审中-公开
标题翻译：压电刺激装置
公开(公告)号：WO2011119951A1
公开(公告)日：2011-09-29
申请号：PCT/US2011/029985
申请日：2011-03-25
申请人： ETHICON, INC. , DIUBALDI, Anthony , WAHLGREN, Stephen , TRACEY, Michael, R.
发明人： DIUBALDI, Anthony , WAHLGREN, Stephen , TRACEY, Michael, R.
IPC分类号： A61N1/36
CPC分类号： A61N1/36014 , A61B5/6874 , A61B2562/028 , A61H23/0245 , A61H2201/5005 , A61N1/32 , A61N1/36007 , A61N1/36017 , A61N1/3787
摘要： A method for stimulating a predetermined body part such as a nerve using a stimulation device including an external non-implantable transmitting device powered by a power source and generating an electrical waveform signal. A surface electrode applies the generated electrical waveform signal transcutaneously. An implantable piezoelectric element receives the applied electrical waveform signal generated transcutaneously and, in turn, causes mechanical deformation resulting in mechanical vibration of the implantable piezoelectric element sufficient to stimulate the predetermined body part. The electrical waveform signal may be either a high frequency continuous waveform or high frequency burst packets.
摘要翻译：一种使用包括由电源供电的外部非植入式发送装置的刺激装置来刺激诸如神经的预定身体部位并产生电波形信号的方法。表面电极经常地施加所生成的电波形信号。可植入压电元件接收经过生成的施加的电波形信号，并且进而引起机械变形，导致可植入式压电元件的机械振动足以刺激预定的身体部位。电波形信号可以是高频连续波形或高频突发分组。

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