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1. 发明申请

WO2010084991A1 COMPRESSION DEVICE USED IN ULTRASONIC MEASUREMENT, COMPRESSION CONTROL METHOD THEREOF, AND PHOTOACOUSTIC MEASUREMENT APPARATUS AND CONTROL METHOD THEREOF 审中-公开
标题翻译：超声波测量中使用的压缩装置，其压缩控制方法及其光电测量装置及其控制方法
公开(公告)号：WO2010084991A1
公开(公告)日：2010-07-29
申请号：PCT/JP2010/051000
申请日：2010-01-20
申请人： CANON KABUSHIKI KAISHA , TOKITA, Toshinobu , NAKAGAWA, Katsumi
发明人： TOKITA, Toshinobu , NAKAGAWA, Katsumi
IPC分类号： A61B5/00 , A61B8/00 , A61B8/08 , A61B10/00 , G01N21/17 , G01N29/24
CPC分类号： A61B5/0095 , A61B5/0091 , A61B5/4312 , A61B5/702 , A61B8/40 , A61B8/406 , A61B8/4281 , A61B90/14 , A61B90/17
摘要： A compression device for compressing a subject that is used in ultrasonic measurement that receives ultrasonic waves from the subject to acquire biological information of the subject, comprising: two compression plates that are used when compressing the subject, and that face each other in a vertical direction with respect to a horizontal plane; a flexible sheet for setting a subject on, which is stretched between upper ends of the two compression plates; a compression mechanism that relatively changes a distance between the two compression plates to sandwich and compress the subject that is set on the flexible sheet through the flexible sheet; and a supply unit for supplying a matching liquid onto the flexible sheet. The apparatus can match an acoustic impedance with a subject and can suppress leaking or overflowing of a matching liquid.
摘要翻译：一种用于压缩用于超声波测量的被摄体的压缩装置，其接收来自被摄体的超声波，以获取被摄体的生物信息，包括：两个压缩板，其在压缩被摄体时使用，并且在垂直方向上彼此面对相对于水平面; 用于设置在两个压缩板的上端之间拉伸的被摄体的柔性片; 压缩机构，其相对地改变两个压缩板之间的距离，以夹持并压缩通过柔性片设置在柔性片材上的被摄体; 以及用于将匹配液体供应到柔性片材上的供应单元。该装置可以将声阻抗与对象相匹配，并可以抑制匹配液体的泄漏或溢出。

2. 发明申请

WO2009035126A1 METHOD OF PRODUCING MICROFLUIDIC DEVICE 审中-公开
标题翻译：生产微流体装置的方法
公开(公告)号：WO2009035126A1
公开(公告)日：2009-03-19
申请号：PCT/JP2008/066798
申请日：2008-09-10
申请人： CANON KABUSHIKI KAISHA , TOKITA, Toshinobu
发明人： TOKITA, Toshinobu
IPC分类号： G01N35/08 , B01J19/00 , B81C1/00 , G01N37/00
CPC分类号： B81C1/00071 , B01J19/0093 , B01J2219/00783 , B01J2219/00826 , B01J2219/00831 , B01J2219/00833 , B01L3/502707 , B01L2200/0689 , B01L2300/0816 , B01L2300/0887 , B81B2201/058
摘要： There is provided a method of producing a microfluidic device including a substrate having a depressed portion and a cover member, whereby to reduce the dispersion of a geometric individual difference and the possibility that a non-joint area can occur in a joint portion between the substrate and the cover member. At the time of producing the microfluidic device, the depressed potion serving as a channel, a chamber and a reservoir is formed in advance in the substrate and a liquid-state energy ray curable resin is applied to the surface of the substrate in which the depressed portion is formed. The energy ray curable resin is cured by an energy ray irradiation unit and caused to serve as the cover on the depressed portion of the substrate, thereby to form the channel, chamber and reservoir.
摘要翻译：提供了一种制造微流体装置的方法，该微流体装置包括具有凹陷部分和覆盖部件的基底，从而减小几何个体差异的分散以及在基底之间的接合部分中可能发生非接合区域的可能性和盖构件。在制造微流体装置时，预先在衬底中形成用作沟道，室和储存器的凹陷部分，并且将液态能量射线固化树脂施加到衬底的表面，其中凹陷形成部分。能量射线固化树脂通过能量射线照射单元固化，并用作衬底的凹陷部分上的盖，从而形成通道，室和储存器。

3. 发明申请

WO2011132405A4 SUBJECT INFORMATION ACQUIRING APPARATUS 审中-公开
标题翻译：主题信息获取设备
公开(公告)号：WO2011132405A4
公开(公告)日：2012-01-12
申请号：PCT/JP2011002287
申请日：2011-04-19
申请人： CANON KK , TOKITA TOSHINOBU , TAKU MASAKAZU
发明人： TOKITA TOSHINOBU , TAKU MASAKAZU
IPC分类号： A61B5/00
CPC分类号： A61B5/0095 , A61B5/0091 , A61B5/4312
摘要： A subject information acquiring apparatus including a cover which intercepts light, two plates which hold a subject, a laser light source, and a probe which receives an acoustic wave generated from the subject to which the light is emitted from the laser light source, wherein the plates, the laser light source, and the probe are covered by the cover, wherein the cover has a first aperture for inserting the subject as part of a subject person into the cover, and a second aperture which can be opened and closed so that an operator can perform a procedure by inserting a hand of the operator into the cover in the position in which the plane extending each of the plates crosses the cover, is used.
摘要翻译：一种被摄体信息获取装置，包括遮挡光的盖，保持被摄体的两个板，激光光源和接收从激光源发射光的被摄体产生的声波的探针，其中，板，激光源和探针被盖覆盖，其中盖具有用于将被摄体作为被摄体人的一部分插入到盖中的第一孔，以及能够打开和关闭的第二孔，操作者可以通过将操作者的手插入盖中，使每个板延伸的平面穿过盖的位置来执行操作。

4. 发明申请

WO2008123591A1 LIQUID CONVEYING APPARATUS AND LIQUID CONVEYING METHOD USING MICRO-FLUID DEVICE 审中-公开
标题翻译：使用微流体装置的液体输送装置和液体输送方法
公开(公告)号：WO2008123591A1
公开(公告)日：2008-10-16
申请号：PCT/JP2008/056722
申请日：2008-03-28
申请人： CANON KABUSHIKI KAISHA , TOKITA, Toshinobu , FUJIMOTO, Kosuke
发明人： TOKITA, Toshinobu , FUJIMOTO, Kosuke
IPC分类号： G01N35/08 , B81B1/00 , G01N37/00
CPC分类号： G01N35/08 , B01L3/50273 , B01L2400/0439 , B01L2400/0496 , F04B43/046 , F04F7/00 , G01N2035/1034 , G01N2035/1058 , Y10T137/206
摘要： An apparatus system for controlling liquid in a fluid channel in a micro-fluid device has an ultrasonic oscillator for conveying liquid. The ultrasonic oscillator oscillates with amplitude modulation. The apparatus system has a holding section for holding the micro-fluid device on the ultrasonic oscillator to allow a micro-fluid device to be removably fitted to it. A liquid conveying method and a liquid conveying unit showing an improved liquid conveying efficiency are provided.
摘要翻译：用于控制微流体装置中的流体通道中的液体的装置系统具有用于输送液体的超声波振荡器。超声波振荡器以振幅调制振荡。装置系统具有用于将微流体装置保持在超声波振荡器上的保持部，以允许微流体装置可移除地装配在该超声波振荡器上。提供了液体输送方法和液体输送单元，其显示出改进的液体输送效率。

5. 发明申请

WO2012150656A1 OBJECT INFORMATION ACQUIRING APPARATUS, CONTROL METHOD THEREOF, AND METHOD FOR DETERMINATION OF CONTACT 审中-公开
标题翻译：获取设备的对象信息，其控制方法及其联系方法
公开(公告)号：WO2012150656A1
公开(公告)日：2012-11-08
申请号：PCT/JP2012/002834
申请日：2012-04-25
申请人： CANON KABUSHIKI KAISHA , TOKITA, Toshinobu
发明人： TOKITA, Toshinobu
IPC分类号： A61B5/00
CPC分类号： A61B5/0095 , A61B5/4312 , A61B5/6843 , A61B5/6844
摘要： The present invention employs an object information acquiring apparatus having: a photoacoustic probe unit including a light irradiating unit which irradiates light, and a probe which receives a photoacoustic wave generated from an object irradiated with light while transmitting an ultrasound wave to the object and receiving a reflected wave thereof; a processor configured to create image information of the object based on the photoacoustic wave; and a controller configured to control irradiation with light, wherein when a first contact condition is defined as a condition in which the object is irradiated with light while the probe is acoustically matched with the object, the controller determines whether or not the photoacoustic probe unit is in the first contact condition by using the reflected wave and enables irradiation with light when the photoacoustic probe unit is in the first contact condition.
摘要翻译：本发明采用一种物体信息获取装置，其具有：光电探测器单元，其包括照射光的光照射单元，以及探测器，其接收从被照射的光产生的光声，同时向对象发送超声波，并接收反射波; 处理器，其被配置为基于所述光声波创建所述对象的图像信息; 以及控制器，其被配置为控制光的照射，其中当所述第一接触条件被定义为在所述探针与所述物体声学匹配时物体被照射的条件下，所述控制器确定所述光声探测单元是否为在第一接触状态下通过使用反射波，并且当光声探针单元处于第一接触状态时能够用光照射。

6. 发明申请

WO2010074103A1 BIOLOGICAL INFORMATION ACQUISITION APPARATUS 审中-公开
标题翻译：生物信息采集装置
公开(公告)号：WO2010074103A1
公开(公告)日：2010-07-01
申请号：PCT/JP2009/071368
申请日：2009-12-16
申请人： CANON KABUSHIKI KAISHA , TOKITA, Toshinobu , FUKUTANI, Kazuhiko , NAKAJIMA, Takao , NAKAGAWA, Katsumi
发明人： TOKITA, Toshinobu , FUKUTANI, Kazuhiko , NAKAJIMA, Takao , NAKAGAWA, Katsumi
IPC分类号： A61B5/00 , A61B8/08
CPC分类号： A61B8/0825 , A61B5/0091 , A61B5/0095 , A61B5/4312
摘要： When a subject is pressed by a plate (1) and an acoustic wave is received by a probe (5) via the plate, the acoustic wave is refracted because of the difference between a sound velocity in the subject and a sound velocity in the plate. When the refraction is not considered, a reduction in resolution occurs. A correction table (92) or a correction formula for correcting image distortion associated with refraction is provided. After image information is acquired, new image information is acquired in accordance with the correction table or the correction formula, and is displayed.
摘要翻译：当受试者被板（1）按压并且经由板通过探针（5）接收声波时，由于被检体中的声速和板中的声速之间的差异，声波被折射。当不考虑折射时，会发生分辨率降低。提供校正表（92）或用于校正与折射相关联的图像失真的校正公式。在获取图像信息之后，根据校正表或校正公式获取新的图像信息，并且显示。

7. 发明申请

WO2009157459A4 ULTRASOUND APPARATUS AND METHOD FOR SIDE LOBE SUPPRESSION 审中-公开
公开(公告)号：WO2009157459A4
公开(公告)日：2009-12-30
申请号：PCT/JP2009/061433
申请日：2009-06-17
申请人： CANON KABUSHIKI KAISHA , TOKITA, Toshinobu
发明人： TOKITA, Toshinobu
IPC分类号： G01S7/52
摘要： A storage unit (106) stores pieces of information regarding intensities of ultrasound waves detected by multiple oscillators (101) in time series. The multiple oscillators (101) receive an ultrasound wave reflected on an object (107), to which a second ultrasound wave (108) generated by an ultrasound probe (102) is focused, in monotonically increasing or decreasing order from an oscillator closest to the object (107) to the most distant one. The second ultrasound wave (108) is transmitted in a direction different from that of a first ultrasound wave (103). Information regarding an intensity of the ultrasound wave reflected on the object (107), which is obtained by storing in the storage unit (106) in monotonically increasing or decreasing order from the oscillator closest to the object (107) to the most distant one, is obtained. This information is subtracted from the pieces of information stored in the storage unit (106). Thus, a received signal from a side lobe is extracted to be subtracted from a whole received signal.

8. 发明申请

WO2009157459A1 ULTRASOUND APPARATUS AND METHOD FOR SIDE LOBE SUPPRESSION 审中-公开
标题翻译：超声波抑制装置和方法
公开(公告)号：WO2009157459A1
公开(公告)日：2009-12-30
申请号：PCT/JP2009061433
申请日：2009-06-17
申请人： CANON KK , TOKITA TOSHINOBU
发明人： TOKITA TOSHINOBU
IPC分类号： G01S7/52
CPC分类号： G01S7/52047
摘要： A storage unit (106) stores pieces of information regarding intensities of ultrasound waves detected by multiple oscillators (101) in time series. The multiple oscillators (101) receive an ultrasound wave reflected on an object (107), to which a second ultrasound wave (108) generated by an ultrasound probe (102) is focused, in monotonically increasing or decreasing order from an oscillator closest to the object (107) to the most distant one. The second ultrasound wave (108) is transmitted in a direction different from that of a first ultrasound wave (103). Information regarding an intensity of the ultrasound wave reflected on the object (107), which is obtained by storing in the storage unit (106) in monotonically increasing or decreasing order from the oscillator closest to the object (107) to the most distant one, is obtained. This information is subtracted from the pieces of information stored in the storage unit (106). Thus, a received signal from a side lobe is extracted to be subtracted from a whole received signal.
摘要翻译：存储单元（106）以时间序列存储与多个振荡器（101）检测的超声波的强度有关的信息。多个振荡器（101）接收在物体（107）上反射的超声波，由超声波探头（102）产生的第二超声波（108）被聚焦，以最接近物体（107）到最远的一个。第二超声波（108）在与第一超声波（103）的方向不同的方向上被发送。通过以最接近对象（107）的振荡器到最远的振荡器以单调递增或递减的顺序存储在存储单元（106）中而获得的关于在物体（107）上反射的超声波的强度的信息，获得。从存储在存储单元（106）中的信息中减去该信息。因此，提取来自旁瓣的接收信号以从整个接收信号中减去。

9. 发明申请

WO2012165169A1 ANALYTE-INFORMATION ACQUISITION APPARATUS 审中-公开
标题翻译：分析信息获取设备
公开(公告)号：WO2012165169A1
公开(公告)日：2012-12-06
申请号：PCT/JP2012/062730
申请日：2012-05-11
申请人： CANON KABUSHIKI KAISHA , TOKITA, Toshinobu , SOMEDA, Yasuhiro
发明人： TOKITA, Toshinobu , SOMEDA, Yasuhiro
IPC分类号： A61B5/00 , G01N21/17 , G01N29/22
CPC分类号： H05B37/0227 , A61B5/0073 , A61B5/0095 , A61B5/489 , A61B5/6835 , A61B2560/04 , G01J1/44 , G01N21/1702 , G01N29/0672 , G01N29/14 , H05B37/02
摘要： To improve the safety of a photoacoustic apparatus by preventing illumination light from being freely emitted. A photoacoustic apparatus includes a position sensor that measures the orientation and/or position of an illumination-light emission end and a control unit that controls light emission from a light source depending on the output of the position sensor.
摘要翻译：通过防止照射光自由发射来提高光声装置的安全性。光声装置包括测量照明光发射端的取向和/或位置的位置传感器和根据位置传感器的输出来控制来自光源的光发射的控制单元。

10. 发明申请

WO2012161104A1 SUBJECT INFORMATION ACQUISITION APPARATUS 审中-公开
标题翻译：主体信息获取装置
公开(公告)号：WO2012161104A1
公开(公告)日：2012-11-29
申请号：PCT/JP2012/062729
申请日：2012-05-11
申请人： CANON KABUSHIKI KAISHA , TOKITA, Toshinobu
发明人： TOKITA, Toshinobu
IPC分类号： A61B5/00 , G01N21/17 , G01N29/24
CPC分类号： A61B5/0062 , A61B5/0095 , A61B8/4444 , A61B8/4477 , A61B8/4483 , G01N21/1702 , G01N29/2418
摘要： The present invention relates to a subject information acquisition apparatus for increasing intensity of photoacoustic signals and improving SNR without increasing scale of the circuit board of the processing apparatus and without increasing the output of the light source. The irradiation position of the illumination light is changed while the substantial total light quantity to the subject is maintained and the light quantity in the irradiated area does not exceed the maximum permissible exposure of skin. The processing apparatus determines the irradiation position and the receiving aperture of the probe and drives the switching apparatus.
摘要翻译：本发明涉及一种用于增加光声信号的强度并且在不增加处理装置的电路板的尺度并且不增加光源的输出的情况下提高SNR的对象信息获取装置。改变照明光的照射位置，同时维持对被摄体的基本总光量，并且照射区域中的光量不超过皮肤的最大允许曝光。处理装置确定探针的照射位置和接收孔径并驱动开关装置。

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