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    • 1. 发明申请
    • COATING OF SURGICAL DEVICES
    • 手术器械涂层
    • WO2005014069A1
    • 2005-02-17
    • PCT/GB2004/003405
    • 2004-08-05
    • PHOQUS PHARMACEUTICALS LIMITEDHALLETT, Martin, DavidWHITEMAN, MarshallSTRINGER, Ian, JamesGREEN, Linda
    • HALLETT, Martin, DavidWHITEMAN, MarshallSTRINGER, Ian, JamesGREEN, Linda
    • A61L27/00
    • B05D1/06A61L27/34
    • The invention provides a method for the coating of a surgical device, wherein the coating is carried out by electrostatic Powder deposition. The device may be a device used in a surgical or diagnostic procedure, including interventional devices as well as implantable devices. Because the coating is applied electrostatically, it is attracted to all parts of the device, not just those parts that are in the 'line of sight' of the spray, as is the case with conventional liquid spray coating. The process allows uniform and reproducible amounts to be deposited and thus drug-eluting coatings can be accurately applied to stents and other surgical devices, resulting in good control over drug release. Furthermore, drug-eluting coats can be applied in a single step, although multiple layers can easily be applied if desired to create a specific drug release profile.
    • 本发明提供了一种外科手术装置的涂覆方法,其中涂层通过静电粉末沉积进行。 该装置可以是用于手术或诊断程序的装置,包括介入装置以及可植入装置。 因为涂层是静电的,所以它被吸引到设备的所有部件上,而不仅仅是那些在喷雾的“视线”部分,就像传统的液体喷涂一样。 该方法允许沉积均匀且可重复的量,因此可以将药物洗脱的涂层精确地应用于支架和其它手术装置,从而很好地控制药物释放。 此外,药物洗脱涂层可以在单一步骤中应用,尽管如果需要多层可以容易地应用以产生特定的药物释放曲线。