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1. 发明申请

WO2011139888A3 ANALYTICAL SYSTEM FOR PERFORMING LABORATORY PROTOCOLS AND ASSOCIATED METHODS 审中-公开
标题翻译：执行实验室协议分析系统及相关方法
公开(公告)号：WO2011139888A3
公开(公告)日：2012-03-15
申请号：PCT/US2011034527
申请日：2011-04-29
申请人： STATSPIN INC , ADEY NILS B , ROB PARRY , KELLAND JAMES , SULLIVAN KEVIN
发明人： ADEY NILS B , ROB PARRY , KELLAND JAMES , SULLIVAN KEVIN
IPC分类号： G01N35/00 , G01N1/38 , G01N35/10
CPC分类号： G01N35/10 , G01N35/00029 , G01N2035/00138 , G01N2035/00326 , G01N2035/00346 , Y10T137/0318
摘要： Systems, devices, and methods for automating laboratory protocols utilizing cooperative efforts between differing components including fluidics, agitation and thermal control for processing a wide variety of disparate laboratory protocols are provided. In one aspect, a sample processing module is provided, including a housing configured to accommodate a pre-identified sample process, a temperature input capable of interfacing with a temperature controller, a fluid input capable of interfacing with an input fluid controller, a fluid output capable of interfacing with an output fluid controller, and a standardized agitation connector capable of interfacing with an agitator. A control system interfaces with the temperature input, fluid input, fluid output, and agitation connector to enable the system to perform laboratory protocols that require complex, sequential fluidic steps in association with the temperature and agitation control.
摘要翻译：提供了使用不同组件之间的协作努力自动化实验室协议的系统，设备和方法，包括用于处理各种不同实验室协议的流体学，搅拌和热控制。在一个方面，提供了一种样品处理模块，其包括被配置为容纳预先识别的样品过程的壳体，能够与温度控制器接口的温度输入，能够与输入流体控制器接口的流体输入，流体输出能够与输出流体控制器接口，以及能够与搅拌器接口的标准化搅拌连接器。控制系统与温度输入，流体输入，流体输出和搅拌连接器接口，使系统能够执行实验室协议，这些实验室协议需要与温度和搅拌控制相关联的复杂的，顺序的流程步骤。

2. 发明申请

WO2010036895A1 CENTRIFUGAL ASSEMBLY AND METHOD FOR OVA DETECTION 审中-公开
标题翻译：离心装配和OVA检测方法
公开(公告)号：WO2010036895A1
公开(公告)日：2010-04-01
申请号：PCT/US2009/058384
申请日：2009-09-25
申请人： STATSPIN, INC. , KELLAND, James , PETITHORY, Henry , SULLIVAN, Kevin
发明人： KELLAND, James , PETITHORY, Henry , SULLIVAN, Kevin
IPC分类号： B04B5/02 , B04B7/00
CPC分类号： B01L3/50215 , A61B10/0038 , B01L2200/025 , B01L2300/0672 , B01L2300/0681 , B01L2300/0854 , B01L2400/0478 , B01L2400/0683
摘要： A centrifugal assembly is provided that can be used in common laboratory fixed angle or swinging bucket centrifuges for the separation of material, such as parasitic ova, based on particle density. The centrifugal assembly allows the fluid level to be gently adjusted to form a meniscus without disruption of the buoyant matter, such as ova. The centrifugal assembly also enables a user to easily and hygienically collect and transfer a measured amount of a sample, such as fecal material, and to break apart and mix the sample with a floatation fluid contained in a centrifuge tube.
摘要翻译：提供了一种离心组件，可用于普通的实验室固定角度或摆动式离心机中，用于基于颗粒密度分离材料，如寄生卵。离心组件允许轻轻地调整液面以形成弯月面而不破坏浮力物质，例如ova。离心组件还使得使用者能够容易且卫生地收集和转移测量量的诸如粪便材料的样品，并且将样品与包含在离心管中的浮选流体分开并混合。

3. 发明申请

WO2011139888A2 ANALYTICAL SYSTEM FOR PERFORMING LABORATORY PROTOCOLS AND ASSOCIATED METHODS 审中-公开
标题翻译：执行实验室协议分析系统及相关方法
公开(公告)号：WO2011139888A2
公开(公告)日：2011-11-10
申请号：PCT/US2011/034527
申请日：2011-04-29
申请人： STATSPIN, INC. , ADEY, Nils, B. , ROB, Parry , KELLAND, James , SULLIVAN, Kevin
发明人： ADEY, Nils, B. , ROB, Parry , KELLAND, James , SULLIVAN, Kevin
IPC分类号： G01N35/00 , G01N35/10 , G01N1/38
CPC分类号： G01N35/10 , G01N35/00029 , G01N2035/00138 , G01N2035/00326 , G01N2035/00346 , Y10T137/0318
摘要： Systems, devices, and methods for automating laboratory protocols utilizing cooperative efforts between differing components including fluidics, agitation and thermal control for processing a wide variety of disparate laboratory protocols are provided. In one aspect, a sample processing module is provided, including a housing configured to accommodate a pre-identified sample process, a temperature input capable of interfacing with a temperature controller, a fluid input capable of interfacing with an input fluid controller, a fluid output capable of interfacing with an output fluid controller, and a standardized agitation connector capable of interfacing with an agitator. A control system interfaces with the temperature input, fluid input, fluid output, and agitation connector to enable the system to perform laboratory protocols that require complex, sequential fluidic steps in association with the temperature and agitation control.
摘要翻译：提供了使用不同组件之间的协作努力自动化实验室协议的系统，设备和方法，包括用于处理各种不同实验室协议的流体学，搅拌和热控制。在一个方面，提供了一种样品处理模块，其包括被配置为容纳预先识别的样品过程的壳体，能够与温度控制器接口的温度输入，能够与输入流体控制器接口的流体输入，流体输出能够与输出流体控制器接口，以及能够与搅拌器接口的标准化搅拌连接器。控制系统与温度输入，流体输入，流体输出和搅拌连接器接口，使系统能够执行实验室协议，这些实验室协议需要与温度和搅拌控制相关联的复杂的，顺序的流程步骤。

4. 发明申请

WO2009143343A1 CENTRIFUGAL DEVICE AND METHOD FOR FLUID COMPONENT SEPARATION 审中-公开
标题翻译：用于流体分量分离的离心装置和方法
公开(公告)号：WO2009143343A1
公开(公告)日：2009-11-26
申请号：PCT/US2009/044837
申请日：2009-05-21
申请人： STATSPIN, INC.
发明人： SOARES, Todd W. , SULLIVAN, Kevin
IPC分类号： B01D43/00
CPC分类号： B01D43/00 , B01L3/50215 , B01L2300/0858 , B01L2300/0864 , B04B5/0407 , B04B7/08
摘要： A rotor is provided for the centrifugal separation of a composite fluid, such as animal or human blood, into components. An inner surface of the rotor includes at least one hydrophobic area having a first surface energy sufficiently low to provide a flow path for a lower density fluid component to flow to the bottom of a central collection chamber after centrifugal separation. A method of separating a composite fluid into components using such a rotor is also provided. Additionally, a method of manufacturing such a rotor is provided.
摘要翻译：提供转子用于将复合流体（例如动物或人体血液）离心分离成组分。转子的内表面包括具有足够低的第一表面能量的至少一个疏水区域，以在离心分离之后提供用于较低密度流体组分流向中心收集室底部的流动路径。还提供了使用这种转子将复合流体分离成组件的方法。另外，提供了制造这种转子的方法。

5. 发明申请

WO2013134583A1 DEVICE AND METHOD FOR CONTROLLING THE TEMPERATURE IN A MOVING FLUID IN A LABORATORY SAMPLE PROCESSING SYSTEM 审中-公开
标题翻译：用于控制实验室样品处理系统中移动流体中的温度的装置和方法
公开(公告)号：WO2013134583A1
公开(公告)日：2013-09-12
申请号：PCT/US2013/029747
申请日：2013-03-08
申请人： STATSPIN, INC.
发明人： SULLIVAN, Kevin, J. , KELLAND, James , NGUYEN, Nhat Khai, L.
IPC分类号： G01N1/28 , G01N33/48
CPC分类号： G01N1/312 , B01F11/0017 , B01F15/00175 , B01F15/00396 , G01N35/00029 , G01N2035/00138 , G01N2035/00396 , G01N2035/00524 , G05D23/19 , Y10T436/112499 , Y10T436/115831
摘要： A temperature control device and method are provided for an analytical system for performing laboratory protocols. The device includes a well within a housing configured to receive a biological specimen according to a predetermined sample process. The specimen is suspended by a holding device in the well. A thermal element is provided in heat exchange communication with fluid in the well. A temperature sensor is located in the well at a location to be covered and uncovered by rocking motion of fluid in the well. A controller, in communication with the thermal element, the temperature sensor, and an agitation system, is operative to control the thermal element in correlation with temperature data, for example, peak temperature data, from the temperature sensor.
摘要翻译：提供了一种用于执行实验室协议的分析系统的温度控制装置和方法。该装置包括：壳体，其构造成根据预定的样品过程接收生物样本。试样由井中的保持装置悬挂。提供与元件中的流体进行热交换连通的热元件。温度传感器位于通过井中的流体的摇摆运动被覆盖和覆盖的位置的井中。与热元件，温度传感器和搅拌系统连通的控制器可操作以与来自温度传感器的温度数据（例如峰值温度数据）相关地控制热元件。

6. 发明申请

WO2008030607A3 CENTRIFUGAL DEVICE AND METHOD FOR OVA DETECTION 审中-公开
公开(公告)号：WO2008030607A3
公开(公告)日：2008-03-13
申请号：PCT/US2007/019639
申请日：2007-09-10
申请人： STATSPIN, INC. , PETITHORY, Henry , KELLAND, James , SULLIVAN, Kevin , MARTIN, Linda
发明人： PETITHORY, Henry , KELLAND, James , SULLIVAN, Kevin , MARTIN, Linda
IPC分类号： G01N9/30
摘要： A centrifugal fecal analyzer device is disclosed for the separation of ova from fecal specimens for microscopic examination. More particularly, the centrifugal device includes a rotor housing, a coring assembly, a mixing chamber centrally located within the housing, and a sediment chamber radially outwardly of the mixing chamber. The coring assembly used to collect a fecal sample is introduced int the rotor assembly through a central top opening, and a detachable handle is removed. The rotor assembly is placed in a centrifuge an spun. A coverslip is placed over the rotor assembly opening, and the ova adhere to the coverslip for analysis using standard microscop methods. In another aspect of the present invention, a centrifugal device is provided in which the ova are delivered through centrifugation to a pipette tip for dispensing onto a microscope slide or coverslip.

7. 发明申请

WO2008030607A2 CENTRIFUGAL DEVICE AND METHOD FOR OVA DETECTION 审中-公开
标题翻译：用于OVA检测的离心装置和方法
公开(公告)号：WO2008030607A2
公开(公告)日：2008-03-13
申请号：PCT/US2007019639
申请日：2007-09-10
申请人： STATSPIN INC , PETITHORY HENRY , KELLAND JAMES , SULLIVAN KEVIN , MARTIN LINDA
发明人： PETITHORY HENRY , KELLAND JAMES , SULLIVAN KEVIN , MARTIN LINDA
IPC分类号： C12M3/00
CPC分类号： B04B5/04 , A61B10/0038 , B01L3/0272 , B01L3/5021 , B01L3/5029 , B01L2300/0681 , B04B5/0414 , B04B7/02 , B04B11/04 , B04B11/06 , B04B2005/0464 , B04B2005/0478
摘要： A centrifugal device and method are provided for the separation of buoyant material such as parasitic ova from fecal matter. A rotor assembly, rotatable about its central axis in a centrifµge, includes a housing with a centrally located top opening leading to a centrally located mixing chamber. An annular sediment chamber is provided, also coaxial about the central axis, connected by a passage with the mixing chamber. A coring assembly is used to retrieve and insert a fecal sample into the mixing chamber for mixing with a flotation fluid. During centrifugation, heavier fecal components pass radially outwardly to the sediment chamber while the ova collect on the inward surface of the flotation fluid. After centrifugation, more flotation fluid is added, if needed, until a meniscus forms at the top opening. A coverslip is placed over the top opening and the ova float to the surface of the fluid and adhere to the coverslip. The coverslip is removed and the ova detected using standard microscopy procedures. In another aspect, a centrifugal device is provided in which the ova are delivered through centrifugation to a pipette tip for dispensing onto a microscope slide or coverslip.
摘要翻译：提供了一种离心装置和方法，用于将浮力物质（例如寄生虫卵）与粪便分离。可以以离心机绕其中心轴线旋转的转子组件包括具有中心定位的顶部开口的壳体，其通向位于中心的混合室。提供环形沉积室，其也围绕中心轴线共轴，通过与混合室的通道连接。取芯组件用于将粪便样品回收并插入到混合室中以与浮选流体混合。在离心过程中，较重的粪便部件径向向外通向沉淀室，而卵子则聚集在浮选流体的内表面上。离心后，如果需要，加入更多的浮选液，直到在顶部开口处形成弯液面。将盖玻片放置在顶部开口上方，并且ova浮动到流体表面并粘附到盖玻片上。取出盖玻片，使用标准显微镜检查检测到ova。在另一方面，提供一种离心装置，其中通过离心将卵子输送到移液管尖端以分配到显微镜载玻片或盖玻片上。

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