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1. 发明申请

WO2016204711A1 INSTRUMENT AND SYSTEM FOR PLACING GRAFT, IMPLANT AND GRAFT MATERIAL FOR MINIMALLY INVASIVE POSTEROLATERAL FUSION 审中-公开
标题翻译：用于放置最小入侵前列腺融合术的植入物，植入物和植物材料的仪器和系统
公开(公告)号：WO2016204711A1
公开(公告)日：2016-12-22
申请号：PCT/US2015/000172
申请日：2015-12-23
申请人： SPINE WAVE, INC. , BOYD, Lawrence M. , RATCLIFFE, John J., Jr. , ADAMSON, Tim E. , GRATA, Paul J.
发明人： BOYD, Lawrence M. , RATCLIFFE, John J., Jr. , ADAMSON, Tim E. , GRATA, Paul J.
IPC分类号： A61F2/00
CPC分类号： A61F2/4601 , A61B17/7094 , A61B17/8811
摘要： In one aspect, an instrument for placing a graft, implant and/or graft material at a target site for enhancing posterolateral fusion between two or more vertebrae is provided which includes a housing and an actuable trigger associated with the housing. A curved rigid access tube extends from the housing, the access tube terminating at a distal end. A sheath is disposed about, and moveable relative to the access tube, and a transmission is disposed in the housing. In an initial state, the sheath extends distally past the distal end of the access tube, a space being defined within the sheath distally of the distal end of the access tube to accommodate the graft, implant and/or graft material. The transmission is configured to cause an incremental displacement of the sheath relative to the distal end of the access tube upon an actuation of the trigger.
摘要翻译：在一个方面，提供了一种用于将移植物，植入物和/或接枝材料放置在靶位置以用于增强两个或更多个椎骨之间的后外侧融合的器械，其包括壳体和与壳体相关联的致动触发器。弯曲的刚性通道管从壳体延伸，入口管终止于远端。护套围绕接近管设置并且可移动，并且传动装置设置在壳体中。在初始状态下，护套向远侧延伸穿过进入管的远端，在入口管的远端远侧限定鞘内以容纳移植物，植入物和/或移植材料的空间。传动装置构造成在触发器的致动时引起护套相对于进入管的远端的增量位移。

2. 发明申请

WO2016200631A1 DEVICE FOR EXPANDING AND SUPPORTING BODY TISSUE 审中-公开
标题翻译：用于扩张和支持身体组织的装置
公开(公告)号：WO2016200631A1
公开(公告)日：2016-12-15
申请号：PCT/US2016/034672
申请日：2016-05-27
申请人： SPINE WAVE, INC.
发明人： MCLEAN, Scott
IPC分类号： A61B17/70
CPC分类号： A61F2/447 , A61B2017/0256 , A61F2/4455 , A61F2/4611 , A61F2002/30169 , A61F2002/30331 , A61F2002/30383 , A61F2002/30556 , A61F2002/30599 , A61F2002/30601 , A61F2002/30607 , A61F2002/30611 , A61F2002/30904 , A61F2002/4475 , A61F2002/4624 , A61F2002/4627
摘要： An expandable device for expanding and supporting body tissue comprises an inferior endplate having an outer surface configured to contact one body tissue surface and a superior endplate having an outer surface configured to contact an opposing body tissue surface. The inferior endplate and the superior endplate are movable relative to each other in a direction of expansion. The device includes an elevator captively supported between the inferior endplate and the superior endplate for independent movement along the direction of expansion. In the first direction the elevator is moved toward said superior endplate to lift the superior endplate and expand the device. In the second direction the elevator moves away from said superior endplate toward said inferior endplate to create a space for insertion of an insert into the expanded device.
摘要翻译：用于扩张和支撑身体组织的可扩张装置包括具有构造成接触一个身体组织表面的外表面的下端板和具有被配置为接触相对的身体组织表面的外表面的上端板。下端板和上端板可以在膨胀方向上相对于彼此移动。该装置包括被固定地支撑在下端板和上端板之间的电梯，用于沿着膨胀方向独立地移动。在第一方向上，电梯朝向所述上端板移动以提升上端板并且使装置膨胀。在第二方向上，电梯从所述上端板朝着所述下端板移动，以形成用于将插入件插入到扩展装置中的空间。

3. 发明申请

WO2015200032A1 MINIMALLY INVASIVE POSTEROLATERAL FUSION 审中-公开
标题翻译：最小的入场费用
公开(公告)号：WO2015200032A1
公开(公告)日：2015-12-30
申请号：PCT/US2015/035939
申请日：2015-06-16
申请人： SPINE WAVE, INC. , BOYD, Lawrence, M. , RATCLIFFE, John, J. Jr. , MORIN, Joshua , MARIGOWDA, Shresta , ADAMSON, Tim, E. , ROBBINS, Daniel , BARBIERI, Thomas, J.
发明人： BOYD, Lawrence, M. , RATCLIFFE, John, J. Jr. , MORIN, Joshua , MARIGOWDA, Shresta , ADAMSON, Tim, E. , ROBBINS, Daniel , BARBIERI, Thomas, J.
IPC分类号： A61B17/70
CPC分类号： A61B17/8802 , A61B17/1757 , A61B17/3421 , A61B17/3423 , A61B17/7077 , A61B2017/3447 , A61F2/4601
摘要： A percutaneous system in which tubular retractors are utilized as a means of access, visualization, and a controlled orientation for preparation of posterior spinal elements and delivery of graft material for posterior spinal fusion. The tubular retractors are affixed to screw extensions to rotate and articulate relative to multi-axial screws percutaneously inserted into respective pedicles of vertebral bodies. The procedure is done bilaterally, although it could be performed unilaterally in cases where the anatomy or surgeon preference dictates. A number of different deployable graft concepts are disclosed, the primary features being to allow for creation of a graft space volume and a means for delivery of the graft material preferred by the surgeon.
摘要翻译：一种经皮系统，其中管状牵开器被用作进入，可视化的方式，以及用于制备后脊柱元件的受控取向和用于后脊柱融合的移植物材料的输送。管状收缩器固定到螺钉延伸部以相对于通过皮下插入到椎体的相应椎弓根中的多轴螺钉旋转和铰接。手术是双侧进行的，虽然可以在解剖学或外科医生偏好决定的情况下单方面进行手术。公开了许多不同的可部署的移植物概念，其主要特征是允许创建移植物空间体积和用于输送外科医生优选的移植物材料的装置。

4. 发明申请

WO2014163936A4 INSERTER FOR EXPANDING AN EXPANDABLE INTERBODY FUSION DEVICE 审中-公开
标题翻译：插件用于扩展可扩展的人体融合装置
公开(公告)号：WO2014163936A4
公开(公告)日：2015-07-09
申请号：PCT/US2014019028
申请日：2014-02-27
申请人： SPINE WAVE INC , RAYMOND SPANKY ALLEN , MCLEAN SCOTT , CULLINAN NICOLA
发明人： RAYMOND SPANKY ALLEN , MCLEAN SCOTT , CULLINAN NICOLA
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61F2/4455 , A61F2/447 , A61F2/4611 , A61F2002/30556 , A61F2002/4623
摘要： An elongate inserter has a distal end releasably connected to an expandable interbody fusion device and a proximal end including a trigger actuator. The interbody fusion device comprises a superior endplate and an inferior endplate that are movable in an expansion direction relative to each other in the intradiscal space. The inserter includes a lifting platform and an elevator that define cooperatively engaging ramps and ramps surfaces that upon operation of the trigger actuator cause the superior and inferior endplates to move relatively away from each other. A driver is supported by the inserter for pushing an insert into the expanded device between the superior and inferior endplates.
摘要翻译：细长插入器具有可释放地连接到可扩张椎体间融合装置的远端和包括触发致动器的近端。椎体间融合装置包括可在椎间盘内空间中相对于彼此在扩张方向上移动的上端板和下端板。插入器包括提升平台和升降器，其限定配合地接合的斜坡和坡道表面，其在触发器致动器的操作时导致上部和下部端板相对远离彼此移动。插入器支持驱动器以将插入件推入上端板和下端板之间的扩张装置中。

5. 发明申请

WO2014163936A2 INSERTER FOR EXPANDING AN EXPANDABLE INTERBODY FUSION DEVICE 审中-公开
标题翻译：用于扩展可扩展内部融合设备的插件
公开(公告)号：WO2014163936A2
公开(公告)日：2014-10-09
申请号：PCT/US2014/019028
申请日：2014-02-27
申请人： SPINE WAVE, INC. , RAYMOND, Spanky, Allen , MCLEAN, Scott , CULLINAN, Nicola
发明人： RAYMOND, Spanky, Allen , MCLEAN, Scott , CULLINAN, Nicola
IPC分类号： A61F2/46
CPC分类号： A61F2/442 , A61F2/4455 , A61F2/447 , A61F2/4611 , A61F2002/30556 , A61F2002/4623
摘要： An elongate inserter has a distal end releasably connected to an expandable interbody fusion device and a proximal end including a trigger actuator. The interbody fusion device comprises a superior endplate and an inferior endplate that are movable in an expansion direction relative to each other in the intradiscal space. The inserter includes a lifting platform and an elevator that define cooperatively engaging ramps and ramps surfaces that upon operation of the trigger actuator cause the superior and inferior endplates to move relatively away from each other. A driver is supported by the inserter for pushing an insert into the expanded device between the superior and inferior endplates.
摘要翻译：细长插入器具有可释放地连接到可膨胀体内融合装置的远端和包括触发器致动器的近端。体内融合装置包括在椎间盘内空间中可相对于彼此在膨胀方向上移动的上端板和下端板。插入器包括提升平台和升降机，其限定协作地接合的斜面和斜面，当触发器执行器操作时，上下端板彼此相对移动。驱动器由插入器支撑，用于将插入件推入上下端板之间的扩展装置。

6. 发明申请

WO2014163929A2 APPARATUS AND METHODS FOR INSERTING AN INTERBODY FUSION DEVICE 审中-公开
标题翻译：用于插入体间融合装置的装置和方法
公开(公告)号：WO2014163929A2
公开(公告)日：2014-10-09
申请号：PCT/US2014/018969
申请日：2014-02-27
申请人： SPINE WAVE, INC. , MALANDAIN, Hugues
发明人： MALANDAIN, Hugues
IPC分类号： A61F2/44
CPC分类号： A61F2/4611 , A61F2/442 , A61F2/447 , A61F2002/30784 , A61F2002/30904 , A61F2002/4475
摘要： An apparatus for use in spinal interbody fusion comprises, in combination, a spinal interbody fusion implant and an inserter releasably attached thereto. The implant comprises a hollow interior through which the inserter extends, the inserter having a tapered distal tip projecting exteriorly beyond the distal end of the implant to initially distract opposing tissue surfaces and to facilitate insertion of the implant into the intradiscal space between the vertebral bodies.
摘要翻译：用于脊椎体间融合的装置包括脊椎体间融合植入物和可释放地附着于其上的插入器的组合。植入物包括中空的内部，插入器通过该内部延伸，插入器具有向外突出于植入物的远端之外的锥形的远端尖端，以初始地分散相对的组织表面并且便于将植入物插入椎体之间的椎间盘间隙中。

7. 发明申请

WO2013187928A1 PEDICLE SCREW EXTENSION FOR USE IN PERCUTANEOUS SPINAL FIXATION 审中-公开
标题翻译：椎弓根螺钉在椎间盘固定术中的应用延伸
公开(公告)号：WO2013187928A1
公开(公告)日：2013-12-19
申请号：PCT/US2012/068413
申请日：2012-12-07
申请人： SPINE WAVE, INC. , McLEAN, Scott
发明人： McLEAN, Scott
IPC分类号： A61B17/70
CPC分类号： A61B17/708 , A61B17/7032 , A61B17/7037 , A61B17/7085
摘要： A bone screw extension assembly for use in placing a connecting rod percutaneously into tissue of a patient comprises a multi-axial bone screw and a screw extension releasably coupled to yoke of the bone screw. The screw extension includes coaxially disposed outer sleeve and inner sleeves that are movable axially relative to each other. A screw engaging member projects radially from the distal end of the inner sleeve and is configured to releasably engage an extension coupling surface on the inner surface of opposed upstanding arms of the yoke. A securement member including cooperative surfaces is defined adjacent the distal end of the inner and outer sleeves that is operable upon relative axial movement of the inner and outer sleeves to radially secure the sleeves together for minimization of splaying and to thereby maintain the engagement of the screw engaging member and the bone screw.
摘要翻译：用于将连杆经皮放置在患者组织中的骨螺钉延伸组件包括多轴骨螺钉和可释放地联接到骨螺钉的轭的螺钉延伸部。螺杆延伸部包括同轴布置的外套筒和可相对于彼此轴向移动的内套筒。螺钉接合构件从内套筒的远端径向地突出并且构造成可释放地接合轭的相对的直立臂的内表面上的延伸联接表面。包括协作表面的固定构件被限定在内套筒和外套筒的远端附近，所述内套筒和外套筒的远端可在内套筒和外套筒的相对轴向移动之间操作以将套筒径向固定在一起以最小化展开并由此维持螺钉接合构件和骨螺钉。

8. 发明申请

WO2013036707A1 LATERAL APPROACH EXPANDABLE SPINAL IMPLANT AND METHOD 审中-公开
标题翻译：横向方法可扩展的脊柱植入物和方法
公开(公告)号：WO2013036707A1
公开(公告)日：2013-03-14
申请号：PCT/US2012/054055
申请日：2012-09-07
申请人： SPINE WAVE, INC. , BARREIRO, Peter
发明人： BARREIRO, Peter
IPC分类号： A61F2/44
CPC分类号： A61F2/447 , A61B2017/0256 , A61F2/4455 , A61F2/4465 , A61F2/4601 , A61F2/4611 , A61F2002/2835 , A61F2002/3008 , A61F2002/30383 , A61F2002/305 , A61F2002/30504 , A61F2002/3052 , A61F2002/30556 , A61F2002/30579 , A61F2002/30599 , A61F2002/30601 , A61F2002/30843 , A61F2002/30904
摘要： An expandable interbody fusion device configured for placement into the intradiscal space between vertebral bodies in a lumbar spine from a lateral approach. The device is expanded by the insertion of a plurality of wafers into the device in situ. The length of the device is configured to extend on the vertebral body endplate from pedicle to pedicle and to reside interiorly of the ring apophysis with at least a portion of the device resting on the area of increased bone density at the posterior portion of the endplate between the pedicles.
摘要翻译：一种可扩展的体内融合装置，其被配置为从侧向方法放置在腰椎的椎体之间的椎间盘内空间中。通过将多个晶片原位插入设备来扩展装置。该装置的长度被配置成在椎体端板上从椎弓根延伸到椎弓根并且在环内部位于内侧的位置，其中装置的至少一部分搁置在终板的后部的增加的骨密度的区域上椎弓根。

9. 发明申请

WO2012148850A2 RADIOPAQUE INJECTABLE NUCLEUS HYDROGEL COMPOSITIONS 审中-公开
标题翻译：放射性注射核糖体组合物
公开(公告)号：WO2012148850A2
公开(公告)日：2012-11-01
申请号：PCT/US2012034667
申请日：2012-04-23
申请人： SPINE WAVE INC , WALKENHORST JARED W , COLLINS KEITH A , LEE DENNIS Y , WILSON THOMAS G , DOUVILLE THOMAS J , BERLEMANN ULRICH
发明人： WALKENHORST JARED W , COLLINS KEITH A , LEE DENNIS Y , WILSON THOMAS G , DOUVILLE THOMAS J , BERLEMANN ULRICH
IPC分类号： A61K49/00
CPC分类号： A61K49/0457
摘要： In one embodiment, the invention relates to a composition suitable for preparing a hydrogel useful as replacement material for all or part of a disc nucleus. The composition comprises:a curable, cross-linkable, non-immunogenic, non-toxic protein comprising a minimum of about 10% and a maximum of about 25% of the hydrogel by weight; a metal contrast agent comprising a minimum of about 2% and a maximum of about 70%) of the hydrogel by weight; and a crosslinker comprising a minimum of about 0.1% and a maximum of about 10% of the hydrogel by weight; wherein the composition has a discernable radiopacity level.
摘要翻译：在一个实施方案中，本发明涉及适于制备可用作椎间盘核的全部或部分的替代材料的水凝胶的组合物。该组合物包含：可固化的，可交联的，非免疫原性的无毒性蛋白，其包含至少约10重量％和最多约25重量％的水凝胶; 包含至少约2％和最多约70％的重量的水凝胶的金属造影剂）和包含至少约0.1重量％和最多约10重量％的水凝胶的交联剂; 其中所述组合物具有可识别的射线不透性水平。

10. 发明申请

WO2011087959A1 SYSTEMS AND METHODS FOR MIXING FLUIDS 审中-公开
标题翻译：混合流体的系统和方法
公开(公告)号：WO2011087959A1
公开(公告)日：2011-07-21
申请号：PCT/US2011/020467
申请日：2011-01-07
申请人： SPINE WAVE, INC. , COLLINS, Keith
发明人： COLLINS, Keith
IPC分类号： A61M37/00
CPC分类号： B01F5/0685 , B01F13/002 , B01F13/0023 , B01F15/0205 , B01F15/0212 , B01F15/0225 , B01F2215/0034
摘要： A syringe-to-syringe mixing apparatus comprises first and second syringes adapted to be coupled at their respective outlets to fluidly connect the syringes. The first syringe includes a plunger having a hollow plunger barrel and a distal end defining a lumen therethrough. The lumen is initially closed by a septum, which in one embodiment is an elastomeric stopper mounted over the end of the plunger. The mixing apparatus further includes a third syringe slidably disposed within the plunger barrel. The third syringe includes a hollow needle adapted to pierce the septum to allow fluid from the third syringe to be injected into fluid within the coupled first and second syringes.
摘要翻译：注射器 - 注射器混合装置包括适于在其各自出口连接以流体连接注射器的第一和第二注射器。第一注射器包括具有中空柱塞筒的柱塞和限定通过其的腔的远端。管腔最初由隔膜封闭，在一个实施例中，隔膜安装在柱塞的端部上。混合装置还包括可滑动地设置在柱塞筒内的第三注射器。第三注射器包括适于刺穿隔膜以允许来自第三注射器的流体被注入耦合的第一和第二注射器内的流体的中空针头。

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