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1. 发明申请

WO2012148850A2 RADIOPAQUE INJECTABLE NUCLEUS HYDROGEL COMPOSITIONS 审中-公开
标题翻译：放射性注射核糖体组合物
公开(公告)号：WO2012148850A2
公开(公告)日：2012-11-01
申请号：PCT/US2012034667
申请日：2012-04-23
申请人： SPINE WAVE INC , WALKENHORST JARED W , COLLINS KEITH A , LEE DENNIS Y , WILSON THOMAS G , DOUVILLE THOMAS J , BERLEMANN ULRICH
发明人： WALKENHORST JARED W , COLLINS KEITH A , LEE DENNIS Y , WILSON THOMAS G , DOUVILLE THOMAS J , BERLEMANN ULRICH
IPC分类号： A61K49/00
CPC分类号： A61K49/0457
摘要： In one embodiment, the invention relates to a composition suitable for preparing a hydrogel useful as replacement material for all or part of a disc nucleus. The composition comprises:a curable, cross-linkable, non-immunogenic, non-toxic protein comprising a minimum of about 10% and a maximum of about 25% of the hydrogel by weight; a metal contrast agent comprising a minimum of about 2% and a maximum of about 70%) of the hydrogel by weight; and a crosslinker comprising a minimum of about 0.1% and a maximum of about 10% of the hydrogel by weight; wherein the composition has a discernable radiopacity level.
摘要翻译：在一个实施方案中，本发明涉及适于制备可用作椎间盘核的全部或部分的替代材料的水凝胶的组合物。该组合物包含：可固化的，可交联的，非免疫原性的无毒性蛋白，其包含至少约10重量％和最多约25重量％的水凝胶; 包含至少约2％和最多约70％的重量的水凝胶的金属造影剂）和包含至少约0.1重量％和最多约10重量％的水凝胶的交联剂; 其中所述组合物具有可识别的射线不透性水平。

2. 发明申请

WO2011087959A1 SYSTEMS AND METHODS FOR MIXING FLUIDS 审中-公开
标题翻译：混合流体的系统和方法
公开(公告)号：WO2011087959A1
公开(公告)日：2011-07-21
申请号：PCT/US2011/020467
申请日：2011-01-07
申请人： SPINE WAVE, INC. , COLLINS, Keith
发明人： COLLINS, Keith
IPC分类号： A61M37/00
CPC分类号： B01F5/0685 , B01F13/002 , B01F13/0023 , B01F15/0205 , B01F15/0212 , B01F15/0225 , B01F2215/0034
摘要： A syringe-to-syringe mixing apparatus comprises first and second syringes adapted to be coupled at their respective outlets to fluidly connect the syringes. The first syringe includes a plunger having a hollow plunger barrel and a distal end defining a lumen therethrough. The lumen is initially closed by a septum, which in one embodiment is an elastomeric stopper mounted over the end of the plunger. The mixing apparatus further includes a third syringe slidably disposed within the plunger barrel. The third syringe includes a hollow needle adapted to pierce the septum to allow fluid from the third syringe to be injected into fluid within the coupled first and second syringes.
摘要翻译：注射器 - 注射器混合装置包括适于在其各自出口连接以流体连接注射器的第一和第二注射器。第一注射器包括具有中空柱塞筒的柱塞和限定通过其的腔的远端。管腔最初由隔膜封闭，在一个实施例中，隔膜安装在柱塞的端部上。混合装置还包括可滑动地设置在柱塞筒内的第三注射器。第三注射器包括适于刺穿隔膜以允许来自第三注射器的流体被注入耦合的第一和第二注射器内的流体的中空针头。

3. 发明申请

WO2012148850A3 RADIOPAQUE INJECTABLE NUCLEUS HYDROGEL COMPOSITIONS 审中-公开
公开(公告)号：WO2012148850A3
公开(公告)日：2012-11-01
申请号：PCT/US2012/034667
申请日：2012-04-23
申请人： SPINE WAVE, INC. , WALKENHORST, Jared, W. , COLLINS, Keith, A. , LEE, Dennis, Y. , WILSON, Thomas, G. , DOUVILLE, Thomas, J. , BERLEMANN, Ulrich
发明人： WALKENHORST, Jared, W. , COLLINS, Keith, A. , LEE, Dennis, Y. , WILSON, Thomas, G. , DOUVILLE, Thomas, J. , BERLEMANN, Ulrich
IPC分类号： A61F2/44 , A61F2/28
摘要： In one embodiment, the invention relates to a composition suitable for preparing a hydrogel useful as replacement material for all or part of a disc nucleus. The composition comprises:a curable, cross-linkable, non-immunogenic, non-toxic protein comprising a minimum of about 10% and a maximum of about 25% of the hydrogel by weight; a metal contrast agent comprising a minimum of about 2% and a maximum of about 70%) of the hydrogel by weight; and a crosslinker comprising a minimum of about 0.1% and a maximum of about 10% of the hydrogel by weight; wherein the composition has a discernable radiopacity level.

4. 发明申请

WO2010019452A3 EMBEDDED MOBILE ANALYTICS IN A MOBILE DEVICE 审中-公开
标题翻译：嵌入式移动设备中的移动分析
公开(公告)号：WO2010019452A3
公开(公告)日：2010-05-06
申请号：PCT/US2009053064
申请日：2009-08-07
申请人： TAPROOT SYSTEMS INC , ANTHONY WAYNE SPIVEY , BLANE E ROCKAFELLOW , SMOAK FRANK ANDREW , COLLINS KEITH
发明人： ANTHONY WAYNE SPIVEY , BLANE E ROCKAFELLOW , SMOAK FRANK ANDREW , COLLINS KEITH
IPC分类号： H04W8/24
CPC分类号： H04W12/10 , H04W12/02
摘要： A method or process enables the collection of data from mobile devices and mobile networks using filtering, compression, encryption, memory management, and power management technologies to collect mobile device metrics at the mobile device (client side), and then transmit these metrics from the mobile device to a server for processing by analytics software. The analytics processing may also occur directly on the mobile device. Policies are determined and configured at the processing server to drive and control the mobile device metrics captured, which may include but are not limited to, data usage (e.g. time of day, amount of data sent/received), voice usage (e.g. time of day, calls in/out of network, dropped calls, call duration), the location of the mobile device, cell patterns (e.g. problem cells, roaming), touch interactions, behavioral analysis (programs used, services uses), battery performance, CPU usage, memory usage, network usage (e.g. 2G, 3G, 3.5G, 4G, Wi-Fi, WiMAX), and the like.
摘要翻译：一种方法或过程使得能够使用过滤，压缩，加密，存储器管理和电力管理技术来收集来自移动设备和移动网络的数据以在移动设备（客户端侧）收集移动设备量度，然后将这些量度从移动设备连接到服务器以供分析软件处理。分析处理也可能直接发生在移动设备上。在处理服务器处确定和配置策略以驱动和控制所捕获的移动设备度量，这可以包括但不限于数据使用（例如，一天中的时间，发送/接收的数据量），语音使用（例如呼叫时间），移动设备的位置，小区模式（例如问题小区，漫游），触摸交互，行为分析（使用的程序，服务使用），电池性能，CPU 使用情况，内存使用情况，网络使用情况（如2G，3G，3.5G，4G，Wi-Fi，WiMAX）等。

5. 发明申请

WO2008086192A1 ARTICULATING INJECTION CANNULA AND SEAL ASSEMBLY 审中-公开
标题翻译：注射肛门和密封组件
公开(公告)号：WO2008086192A1
公开(公告)日：2008-07-17
申请号：PCT/US2008/050251
申请日：2008-01-04
申请人： SPINE WAVE INC. , COLLINS, Keith , WILSON, Thomas, G. , RAYMOND, Spanky, A.
发明人： COLLINS, Keith , WILSON, Thomas, G. , RAYMOND, Spanky, A.
IPC分类号： A61B17/58
CPC分类号： A61B17/8811 , A61B17/8816 , A61F2/4611 , A61F2/4657 , A61F2/4684 , A61F2002/444 , A61F2002/4627 , A61F2002/4628 , A61F2002/4663
摘要： An assembly for sealably injecting a fluent material into an intradiscal space accessed through an opening in the annulus of a spinal disc comprises a cannula having a passageway for injecting the fluent material therethrough into the intradiscal space, a seal having a sealing surface for sealing engagement with the outer surface of the disc annulus and defining a central opening for, and an articulating joint defined between the central opening of the seal and the cannula configured to permit relative articulation between the components. The assembly may further comprise an anchor element extending through the central opening of the seal, the anchor element including an elongated threaded body sized for threaded engagement within the opening in the disc annulus and having a head configured to engage a distal end of the cannula.
摘要翻译：用于将流体材料密封地注入通过脊椎盘环的开口进入的椎间盘内空间的组件包括具有用于将流体通过其注入椎间盘内空间的通道的套管，密封件，具有用于与所述盘环的外表面和限定在所述密封件的所述中心开口和所述套管之间限定的中心开口，所述关节接头被构造成允许所述部件之间的相对铰接。组件还可以包括延伸穿过密封件的中心开口的锚定元件，锚定元件包括细长螺纹体，其尺寸适于螺旋接合在盘环空间内的开口内，并且具有构造成接合套管远端的头部。

6. 发明申请

WO2010019452A2 EMBEDDED MOBILE ANALYTICS IN A MOBILE DEVICE 审中-公开
标题翻译：嵌入式移动分析仪在移动设备中的应用
公开(公告)号：WO2010019452A2
公开(公告)日：2010-02-18
申请号：PCT/US2009/053064
申请日：2009-08-07
申请人： TAPROOT SYSTEMS, INC. , Anthony Wayne Spivey , Blane E Rockafellow , SMOAK, Frank, Andrew , COLLINS, Keith
发明人： Anthony Wayne Spivey , Blane E Rockafellow , SMOAK, Frank, Andrew , COLLINS, Keith
IPC分类号： H04W8/24
CPC分类号： H04W12/10 , H04W12/02
摘要： A method or process enables the collection of data from mobile devices and mobile networks using filtering, compression, encryption, memory management, and power management technologies to collect mobile device metrics at the mobile device (client side), and then transmit these metrics from the mobile device to a server for processing by analytics software. The analytics processing may also occur directly on the mobile device. Policies are determined and configured at the processing server to drive and control the mobile device metrics captured, which may include but are not limited to, data usage (e.g. time of day, amount of data sent/received), voice usage (e.g. time of day, calls in/out of network, dropped calls, call duration), the location of the mobile device, cell patterns (e.g. problem cells, roaming), touch interactions, behavioral analysis (programs used, services uses), battery performance, CPU usage, memory usage, network usage (e.g. 2G, 3G, 3.5G, 4G, Wi-Fi, WiMAX), and the like.
摘要翻译：一种方法或过程使得能够使用过滤，压缩，加密，存储器管理和电力管理技术从移动设备和移动网络收集数据，以在移动设备（客户端）收集移动设备度量，然后从移动设备到服务器进行分析软件处理。分析处理也可以直接发生在移动设备上。在处理服务器处确定和配置策略以驱动和控制捕获的移动设备指标，其可以包括但不限于数据使用（例如，一天中的时间，发送/接收的数据量），语音使用（例如，网络呼叫，呼叫延迟，呼叫持续时间），移动设备的位置，小区模式（例如问题单元，漫游），触摸交互，行为分析（使用的程序，服务使用），电池性能，CPU 使用情况，内存使用情况，网络使用情况（例如2G，3G，3.5G，4G，Wi-Fi，WiMAX）等。

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