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1. 发明申请

WO2011075194A1 SELF-AIMING DIRECTABLE ACOUSTIC TRANSDUCER ASSEMBLY FOR INVASIVE MEDICAL DEVICE APPLICATIONS 审中-公开
标题翻译：用于入侵医疗设备应用的自激式直接传声器组件
公开(公告)号：WO2011075194A1
公开(公告)日：2011-06-23
申请号：PCT/US2010/049163
申请日：2010-09-16
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , SLIWA, John, W. , MORSE, Stephen
发明人： SLIWA, John, W. , MORSE, Stephen
IPC分类号： A61B17/22
CPC分类号： A61B8/12 , A61B5/6885 , A61B8/085 , A61B8/4254 , A61B8/429 , A61B8/445 , A61B18/1492 , A61B2090/378 , A61B2090/3784 , A61M37/0092 , H04R17/00
摘要： A directable acoustic transducer assembly (120) for use in a medical insertion device (MID) (100). In an embodiment, the assembly aims an acoustic signal in response to a sensed or detected force/load imposed on the MID (100). The directable acoustic transducer assembly (120) includes a switch array (126) and directional acoustic transducer elements (160a-160h). The switch array (126) responds to the force/load and activates the directional acoustic transducer elements (160a-160h) closest to the source of the force or load. The switch array (126) may include switches (126a-126h), at least one of which responses to a force or load and may activate directional acoustic transducer elements (160a-106h) having a target tissue in the field of view. The assembly includes embodiments that are responsive to various loads. A directable acoustic transducer assembly (120) may be part of a diagnostic and/or therapeutic system, (e.g., an RF ablation system (700)).
摘要翻译：一种用于医疗插入装置（MID）（100）的可直接声换能器组件（120）。在一个实施例中，组件响应于施加在MID（100）上的感测或检测到的力/负载来瞄准声信号。可直接声换能器组件（120）包括开关阵列（126）和定向声换能器元件（160a-160h）。开关阵列（126）响应于力/负载并激活最靠近力或负载源的定向声换能器元件（160a-160h）。开关阵列（126）可以包括开关（126a-126h），其中至少一个响应于力或负载并且可以激活在视野中具有目标组织的定向声换能器元件（160a-106h）。组件包括响应于各种负载的实施例。可指示的声换能器组件（120）可以是诊断和/或治疗系统的一部分（例如，RF消融系统（700））。

2. 发明申请

WO2009085998A1 APPARATUS AND METHOD FOR COOLING AND MOVING ABLATION ELEMENTS 审中-公开
标题翻译：用于冷却和移动元件的装置和方法
公开(公告)号：WO2009085998A1
公开(公告)日：2009-07-09
申请号：PCT/US2008/087508
申请日：2008-12-18
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , MA, Zhenyi , KLIMOVITCH, Gleb V. , SLIWA, John W.
发明人： MA, Zhenyi , KLIMOVITCH, Gleb V. , SLIWA, John W.
IPC分类号： A61B19/00
CPC分类号： A61B18/14 , A61B18/1492 , A61B2018/00023 , A61B2018/0016 , A61B2018/00351 , A61B2018/00363 , A61B2018/00577 , A61B2018/141 , A61B2018/1467 , A61N7/022
摘要： A medical device (10) comprising a cell (12) including an ablation element (18) and a carrier (16) configured to receive at least a portion of said ablation element (18) is disclosed. The medical device (10) further comprises a tube (30) enclosing the cell (12). At least a portion of the tube (30) includes a membrane and the tube (30) includes at least one hole (36) proximate the ablation element (18) for facilitating fluid flow. The medical device (10) further comprises a fluid inlet (32) for providing fluid to the interior of the tube. A method of using the medical device is also disclosed.
摘要翻译：公开了一种医疗设备（10），包括包括消融元件（18）的单元（12）和被配置为容纳所述消融元件（18）的至少一部分的载体（16）。医疗装置（10）还包括封闭电池（12）的管（30）。管（30）的至少一部分包括膜，并且管（30）包括靠近消融元件（18）的至少一个孔（36），以便于流体流动。医疗装置（10）还包括用于向管的内部提供流体的流体入口（32）。还公开了使用该医疗装置的方法。

3. 发明申请

WO2008098101A3 DEVICE AND METHOD FOR HIGH INTENSITY FOCUSED ULTRASOUND ABLATION WITH ACOUSTIC LENS 审中-公开
标题翻译：高强度聚焦超声波吸收与声学透镜的装置和方法
公开(公告)号：WO2008098101A3
公开(公告)日：2008-11-20
申请号：PCT/US2008053263
申请日：2008-02-07
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , SLIWA JOHN W , GOETZ JOHN P , MA ZHENYI , CALLAGHAN FRANK , CICIARELLI TIMOTHY E , TENG JENNIFER , MORSE STEPHEN A
发明人： SLIWA JOHN W , GOETZ JOHN P , MA ZHENYI , CALLAGHAN FRANK , CICIARELLI TIMOTHY E , TENG JENNIFER , MORSE STEPHEN A
IPC分类号： A61B8/14
CPC分类号： A61N7/02 , A61N2007/0056 , A61N2007/006 , A61N2007/0078
摘要： A high intensity focused ultrasound transducer (10) includes an ultrasonic emitter (12) having a surface (16) that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens (14) acoustically coupled to surface (16) in the beam path of the ultrasonic energy, such that the lens can direct ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf (30), a heat sink, or an acoustic matching layer (28), to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, surface (16) is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.
摘要翻译：高强度聚焦超声换能器（10）包括具有沿着光束路径发射超声波能量的表面（16）的超声波发射器（12），至少一个声学耦合到表面（16）的低衰减聚合物超声波透镜（14）超声能量的光束路径，使得透镜可以在至少一个方向上引导超声波能量，以及至少一个应力消除特征，例如切口（30），散热器或声匹配层（28），以减轻换能器内的热膨胀失配应力。为了简化制造，表面（16）通常是平坦的或单调的曲线。透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。预期至少一个超声波透镜相对于超声发射器的任何取向和定位。通过模制，铸造或热成型镜片进一步简化制造。

4. 发明申请

WO2009082740A1 FINGER-MOUNTED OR ROBOT-MOUNTED TRANSDUCER DEVICES AND RELATED METHODS OF USE AND MANUFACTURE 审中-公开
标题翻译：手指安装或机器人安装的传感器装置及相关使用和制造方法
公开(公告)号：WO2009082740A1
公开(公告)日：2009-07-02
申请号：PCT/US2008/088034
申请日：2008-12-22
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , SLIWA, John, W.
发明人： SLIWA, John, W.
IPC分类号： A61B18/04
CPC分类号： A61N7/02 , A61B8/4227 , A61B8/4272 , A61B34/30 , A61B34/71 , A61B90/53 , A61B2018/00023
摘要： A transducer device (10) includes mounting body (12) coupling device (10) to an operator's digit or to a deployable member of a robotic surgical system for mounting and manipulating the device. The device includes a transducer housing (14) coupled to mounting body (12) having a receiving portion and includes therapy delivery transducer (16) and a fluid irrigation lumen (18) coupled to the receiving portion and connected to an energy supply to transmit energy from an emitting surface (20) toward target tissue (TT). The device can include gas reservoir (28) configured to decrease energy transfer thereacross. The device can include a membrane (30) coupled located adjacent the emitting surface and a lumen (18) for providing fluid or gel to membrane (30). The device can include imaging capability (16'), diverse sensors (13,13') to assess tissue and therapy delivery results therefrom and also spatial tracking elements (for magnetic, electrical field, and fluoroscopic location/orientation).
摘要翻译：换能器装置（10）包括将装置（10）连接到操作人员的数字上或者用于安装和操纵装置的机器人手术系统的可展开构件的安装体（12）。该装置包括耦合到具有接收部分的安装体（12）的换能器壳体（14），并且包括联接到接收部分并连接到能量传递能量的治疗输送换能器（16）和流体冲洗内腔（18）从发射表面（20）朝向靶组织（TT）。该装置可以包括被配置为减少其上的能量传递的气体储存器（28）。该装置可以包括耦合定位在发射表面附近的膜（30）和用于向膜（30）提供流体或凝胶的内腔（18）。该装置可以包括成像能力（16'），各种传感器（13,13'），用于评估组织和治疗传递结果，以及空间跟踪元件（用于磁场，电场和荧光检查位置/取向）。

5. 发明申请

WO2009079158A1 SYSTEM FOR DISPLAYING DATA RELATING TO ENERGY EMITTING TREATMENT DEVICES TOGETHER WITH ELECTROPHYSIOLOGICAL MAPPING DATA 审中-公开
标题翻译：用于显示与电生理图像数据相关的能量发射处理设备的数据系统
公开(公告)号：WO2009079158A1
公开(公告)日：2009-06-25
申请号：PCT/US2008/084302
申请日：2008-11-21
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , SLIWA, John W.
发明人： SLIWA, John W.
IPC分类号： A61B5/02
CPC分类号： A61B5/042 , A61B5/044 , A61B34/20 , A61B34/25 , A61N7/02
摘要： A system and method for treatment of tissue is provided. An electronic control unit (22) is configured to generate displays signals used to create a graphical user interface. The display signals are generated in response to a first set of position signals indicative of the position of an electrophysiology mapping electrode relative to the tissue (12) and a second set of position signals indicative of the position of a treatment device (20), such as a high intensity focused ultrasound transducer, that is configured to generate a beam of energy towards a selected region in the tissue (12). The graphical user interface displays an electrophysiology map of the tissue and an image of at least one of the treatment device and a beam of energy which may be superimposed on the electrophysiology map.
摘要翻译：提供了一种用于治疗组织的系统和方法。电子控制单元（22）被配置为产生用于创建图形用户界面的显示信号。响应于指示电生理学映射电极相对于组织（12）的位置的第一组位置信号和指示治疗装置（20）的位置的第二组位置信号而产生显示信号，例如作为高强度聚焦超声换能器，其被配置为朝向组织（12）中的选定区域产生能量束。图形用户界面显示组织的电生理学图，以及可以叠加在电生理学图上的治疗装置和能量束中的至少一个的图像。

6. 发明申请

WO2009085485A3 TEMPLATE SYSTEM AND METHODS 审中-公开
公开(公告)号：WO2009085485A3
公开(公告)日：2009-07-09
申请号：PCT/US2008/084557
申请日：2008-11-24
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , SLIWA, John W. , EBY, Thomas B.
发明人： SLIWA, John W. , EBY, Thomas B.
IPC分类号： A61B18/18
摘要： Template systems and methods for various procedures (e.g., tissue ablation procedures) are disclosed. An exemplary template system (10) comprises a track (12) having at least one suction port (22). The at least one suction port (22) anchors the track (12) to a tissue after the track (12) is positioned adjacent a target area. The template system (10) may further comprise a transducer (14) operatively associated with the track (12). Exemplary transducers include imaging transducers and ablating transducers. The transducer (14) is guided by the track (12) adjacent the target area while the transducer (14) is moved along the track (12) for a procedure. One or more umbilical (16a, 16b) may provide a conduit to the track (12) and/or transducer (14) so that the template system (10) may be positioned in a patient's body (e.g., for a procedure on the patient's heart) and operated remotely by a physician or other user from outside of the patient's body.

7. 发明申请

WO2009085485A2 TEMPLATE SYSTEM AND METHODS 审中-公开
标题翻译：模式系统和方法
公开(公告)号：WO2009085485A2
公开(公告)日：2009-07-09
申请号：PCT/US2008084557
申请日：2008-11-24
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , SLIWA JOHN W , EBY THOMAS B
发明人： SLIWA JOHN W , EBY THOMAS B
IPC分类号： A61B18/14
CPC分类号： A61B18/18 , A61B8/12 , A61B8/4209 , A61B8/4236 , A61B8/4245 , A61B8/4281 , A61B8/445 , A61B18/148 , A61B18/1815 , A61B18/20 , A61B2017/00867 , A61B2018/00011 , A61B2018/00273 , A61B2018/00291 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2090/378 , A61B2218/002 , C08L2201/12
摘要： Template systems and methods for various procedures (e.g., tissue ablation procedures) are disclosed. An exemplary template system (10) comprises a track (12) having at least one suction port (22). The at least one suction port (22) anchors the track (12) to a tissue after the track (12) is positioned adjacent a target area. The template system (10) may further comprise a transducer (14) operatively associated with the track (12). Exemplary transducers include imaging transducers and ablating transducers. The transducer (14) is guided by the track (12) adjacent the target area while the transducer (14) is moved along the track (12) for a procedure. One or more umbilical (16a, 16b) may provide a conduit to the track (12) and/or transducer (14) so that the template system (10) may be positioned in a patient's body (e.g., for a procedure on the patient's heart) and operated remotely by a physician or other user from outside of the patient's body.
摘要翻译：公开了用于各种程序（例如，组织消融程序）的模板系统和方法。示例性模板系统（10）包括具有至少一个吸入口（22）的轨道（12）。所述至少一个吸入口（22）在所述轨道（12）邻近目标区域定位之后将轨道（12）锚固到组织。模板系统（10）还可以包括与轨道（12）可操作地相关联的换能器（14）。示例性换能器包括成像换能器和消融换能器。传感器（14）由邻近目标区域的轨道（12）引导，同时换能器（14）沿着轨道（12）移动以用于过程。一个或多个脐带（16a，16b）可以向轨道（12）和/或换能器（14）提供导管，使得模板系统（10）可以定位在患者体内（例如，用于患者的身体上的程序心脏），并由医生或其他用户从患者身体外部远程操作。

8. 发明申请

WO2009082634A1 ULTRASOUND ENDOVASCULAR CLEARING DEVICE 审中-公开
标题翻译：超声内镜清除装置
公开(公告)号：WO2009082634A1
公开(公告)日：2009-07-02
申请号：PCT/US2008/086558
申请日：2008-12-12
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , SLIWA, John, W.
发明人： SLIWA, John, W.
IPC分类号： A61B17/00
CPC分类号： A61B17/22012 , A61B2017/22015 , A61B2017/22017
摘要： An ultrasonic endovascular clearing device for use in a bodily lumen includes a powering handle configured to enclose one or more acoustic drivers (14), an acoustic amplifier and/or acoustic matching section including one or more amplifiers and/or matching elements (16) and a driven wire (18). The acoustic drivers (14) are configured to produce acoustic vibration in the ultrasonic frequency range. The amplifier/matching section (16) matches and amplifies the acoustic vibration and drives the wire (18) accordingly. The wire (18) cleans due to one or both of a) its asymmetric shape being driven, b) its feature-enhanced surface being driven, whether on an asymmetric wire or not. The driving is pulsed or continuous, cavitating or noncavitating, and torsional or radial/lateral in its possible operational embodiments. A drug may be used by or delivered by the device and wire/tissue parameter sensing is optionally provided.
摘要翻译：用于身体管腔的超声波血管内清除装置包括配置成封闭一个或多个声学驱动器（14）的动力手柄，包括一个或多个放大器和/或匹配元件（16）的声学放大器和/或声学匹配部分，以及驱动线（18）。声学驱动器（14）构造成在超声波频率范围内产生声振动。放大器/匹配部分（16）匹配和放大声振动并相应地驱动线（18）。线（18）由于a）其不对称形状被驱动中的一个或两个而被清洁，b）其特征增强表面被驱动，无论是否在非对称线上。在其可能的操作实施例中，驱动是脉冲式或连续的，气蚀的或非驱动的，以及扭转的或径向的/侧向的。药物可以由装置使用或输送，并且可选地提供线/组织参数感测。

9. 发明申请

WO2011075193A1 APPRATUS AND METHODS FOR ACOUSTIC MONITORING OF ABLATION PROCEDURES 审中-公开
标题翻译：呼吸程序声调监测的方法和方法
公开(公告)号：WO2011075193A1
公开(公告)日：2011-06-23
申请号：PCT/US2010/049161
申请日：2010-09-16
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , SLIWA, John, W. , MA, Zhenyi , GOETZ, John, P. , MORSE, Stephen, A.
发明人： SLIWA, John, W. , MA, Zhenyi , GOETZ, John, P. , MORSE, Stephen, A.
IPC分类号： A61B8/00
CPC分类号： A61B18/1492 , A61B7/00 , A61B8/0833 , A61B8/0858 , A61B8/0883 , A61B8/12 , A61B8/4472 , A61B8/4483 , A61B8/462 , A61B8/463 , A61B8/5215 , A61B2017/00106 , A61B2018/00577 , A61B2018/00791 , A61B2018/00839 , A61B2018/1861 , A61B2090/065
摘要： A system for ablating tissue includes a catheter having an elongate body, with at least one ablation element (e g, RF electrode) and at least one acoustic transducer located within the body's tip region The transducer receives acoustic signals from proximate the tip region The system also includes a monitoring unit coupled to the transducer to interpret the received acoustic signals as data regarding at least one therapeutic parameter (e g, pre-pop detection, lesion making progress, tissue interface detection, tissue contact force, tissue contact establishment, bubble spatial distribution, bubble depth, bubble size, bubble size distnbution, tissue interface distance, tissue interface position, tissue attenuation, tissue thickness, lesion spectral fingerpπnt) The monitoring unit is operable to provide feedback to a practitioner, such as graphical, audible, and/or haptic output of sensed data, and may also be operable to control operation of the at least one ablation element in response thereto.
摘要翻译：用于消融组织的系统包括具有细长主体的导管，其具有至少一个消融元件（例如，RF电极）和位于主体尖端区域内的至少一个声换能器。换能器从尖端区域接近声信号系统还包括耦合到换能器的监测单元，以将接收到的声学信号解释为关于至少一个治疗参数的数据（例如，预弹头检测，病变进行，组织界面检测，组织接触力，组织接触建立，气泡空间分布，气泡深度，气泡尺寸，气泡尺寸分布，组织界面距离，组织界面位置，组织衰减，组织厚度，病变光谱指纹）监测单元可操作以向实践者提供反馈，例如图形，听觉和/或触觉输出感测数据，并且还可以用于响应于控制至少一个消融元件的操作于此。

10. 发明申请

WO2008098099A2 HIGH INTENSITY FOCUSED ULTRASOUND TRANSDUCER WITH ACOUSTIC LENS 审中-公开
标题翻译：带有声学透镜的高强度聚焦超声换能器
公开(公告)号：WO2008098099A2
公开(公告)日：2008-08-14
申请号：PCT/US2008/053260
申请日：2008-02-07
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , SLIWA, John W. , GOETZ, John P. , MA, Zhenyi , TENG, Jennifer , MORSE, Stephen A. , CALLAGHAN, Frank , CICIARELLI, Timothy E.
发明人： SLIWA, John W. , GOETZ, John P. , MA, Zhenyi , TENG, Jennifer , MORSE, Stephen A. , CALLAGHAN, Frank , CICIARELLI, Timothy E.
IPC分类号： A61B8/00
CPC分类号： A61N7/02 , A61B8/4272 , A61B17/2251
摘要： A high intensity focused ultrasound transducer (10) includes an ultrasonic emitter (12) having a surface (16) that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens (14) acoustically coupled to surface (16) in the beam path of the ultrasonic energy, such that the lens can direct ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf (30), a heat sink, or an acoustic matching layer (28), to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, surface (16) is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.
摘要翻译：高强度聚焦超声波换能器（10）包括具有沿光束路径发射超声波能量的表面（16）的超声波发射器（12），至少一个低衰减聚合物超声波透镜（14）声学地耦合到超声能束路径中的表面（16），使得透镜可以在至少一个方向上引导超声能量，并且至少一个应力缓解特征，诸如切口（30），散热器，或声匹配层（28），以减轻换能器内的热膨胀失配应力。为了简化制造，表面（16）通常为平面或单调曲线。镜片可以采用各种形状，包括菲涅耳特征，并可以聚焦，准直或散焦超声波能量。预期至少一个超声波透镜相对于超声波发射器的任何定向和定位。通过模制，铸造或热成型镜片可进一步简化制造。

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