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1. 发明申请

WO2008139489A1 DYNAMIC MOTION VECTOR ANALYSIS METHOD 审中-公开
标题翻译：动态运动矢量分析方法
公开(公告)号：WO2008139489A1
公开(公告)日：2008-11-20
申请号：PCT/IN2008/000229
申请日：2008-04-08
申请人： ALLGO EMBEDDED SYSTEMS PRIVATE LIMITED , FARFADE, Sachin, Sudhakar , SINGH, Satendra, Pal , RAJARAM, Kiran , SHARMA, Abhay
发明人： FARFADE, Sachin, Sudhakar , SINGH, Satendra, Pal , RAJARAM, Kiran , SHARMA, Abhay
IPC分类号： H04N7/015 , H04N7/26
CPC分类号： H04N19/433 , H04N19/44 , H04N19/51 , H04N19/52 , H04N19/61
摘要： ABSTRACT The proposed Dynamic Motion Vector Analysis method applies to the motion compensation module of a video decoder system. The method analyzes the motion-vectors of a given region of picture frame and outputs a set of regions to be fetched from the reference frames stored in the external memory. The size and number of regions are decided by a hierarchical method that uses a set of user-defined input thresholds. Pre-processing of the motion vectors associated with the given region allows the method to handle reference data to be fetched from multiple reference frames in the same framework. A complementary dynamic batch (region of operation) size strategy that works along with MV-analysis is also proposed to help utilize the on-chip memory resources more efficiently.
摘要翻译：摘要提出的动态矢量分析方法适用于视频解码系统的运动补偿模块。该方法分析图像帧的给定区域的运动矢量，并输出要从存储在外部存储器中的参考帧中取出的一组区域。区域的大小和数量由使用一组用户定义的输入阈值的分层方法决定。与给定区域相关联的运动矢量的预处理允许该方法处理在同一框架中从多个参考帧获取的参考数据。还提出了与MV分析一起工作的互补动态批次（操作区域）大小策略，以更有效地利用片上内存资源。

2. 发明申请

WO2008041244B1 A METHOD FOR THE IDENTIFICATION OF POTENTIAL BIOMARKERS AND DRUG TARGETS IN BRAIN PLASTICITY RELATED DISORDERS 审中-公开
标题翻译：一种鉴定脑部塑性相关疾病潜在生物标志物和药物靶点的方法
公开(公告)号：WO2008041244B1
公开(公告)日：2008-10-09
申请号：PCT/IN2007000452
申请日：2007-10-01
申请人： COUNCIL SCIENT IND RES , SHARMA ABHAY , SINGH PRIYANKA , FARHAN MD
发明人： SHARMA ABHAY , SINGH PRIYANKA , FARHAN MD
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/158
摘要： The invention relates to identification of potential biomarkers and drug targets in brain plasticity related disorders. In particular, the invention describes a system level model of brain plasticity related disorders in the fruit fly Drosophila
摘要翻译：本发明涉及鉴定脑可塑性相关疾病中的潜在生物标志物和药物靶标。具体而言，本发明描述了果蝇果蝇中脑可塑性相关障碍的系统级模型

3. 发明申请

WO2008041244A2 A METHOD FOR THE IDENTIFICATION OF POTENTIAL BIOMARKERS AND DRUG TARGETS IN BRAIN PLASTICITY RELATED DISORDERS 审中-公开
标题翻译：一种鉴定脑部塑性相关疾病潜在生物标志物和药物靶点的方法
公开(公告)号：WO2008041244A2
公开(公告)日：2008-04-10
申请号：PCT/IN2007/000452
申请日：2007-10-01
申请人： COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH , SHARMA, Abhay , SINGH, Priyanka , FARHAN, Md.
发明人： SHARMA, Abhay , SINGH, Priyanka , FARHAN, Md.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/158
摘要： The invention relates to identification of potential biomarkers and drug targets in brain plasticity related disorders. In particular, the invention describes a system level model of brain plasticity related disorders in the fruit fly Drosophila melanogaster , thereby identifying potential biomarkers and drug targets in epileptogenesis and associated conditions. The invention also provides a means of screening therapeutic agents against epilepsy and related disorders using gene expression profiling in Drosophila.
摘要翻译：本发明涉及鉴定脑可塑性相关病症中潜在的生物标志物和药物靶标。具体而言，本发明描述了果蝇果蝇中脑可塑性相关障碍的系统级模型，由此鉴定癫痫发生和相关病症中的潜在生物标志物和药物靶标。本发明还提供了使用果蝇中的基因表达谱来筛选针对癫痫和相关病症的治疗剂的方法。

4. 发明申请

WO2005063009A1 A PROCEDURE FOR SCREENING OF NEUROACTIVE SUBSTANCE AND THE ASSOCIATED NEURAL PLASTICITY 审中-公开
标题翻译：筛选神经活性物质和相关神经塑性的程序
公开(公告)号：WO2005063009A1
公开(公告)日：2005-07-14
申请号：PCT/IN2003/000402
申请日：2003-12-29
申请人： COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH , SHARMA, Abhay
发明人： SHARMA, Abhay
IPC分类号： A01K67/033
CPC分类号： A61K49/0008
摘要： The invention relates to a procedure for screening of neuroactive substance and the associated neural plasticity by treating the fruitfly Drosophila melanogaster adult males with fly medium containing either of the neuroactive compounds strychnine, pentylenetetrazol, pilocarpine hydrochloride, tetraethylammonium chloride, lithium carbonate and ethosuximide, subjecting flies to negative geotaxis and horizontal locomotor assays, observing the height climbed and distance walked by and the climbing speed of the flies wherein an altered height climbed by flies under drug treatment and a long-lasting alteration in climbing speed of flies after drug withdrawal is most characteristic of the neuractive compounds.
摘要翻译：本发明涉及通过用含有神经活性化合物士的宁，戊四氮，盐酸毛果芸香碱，四乙基氯化铵，碳酸锂和乙酰亚胺二者的飞行培养物处理果蝇果蝇黑色素成年雄性来筛选神经活性物质和相关神经可塑性的方法，观察负极地形和水平运动测定，观察飞行高度爬升和距离以及攀爬速度，其中药物治疗下苍蝇升高的高度和药物戒断后苍蝇攀爬速度的持久变化最为特征的神经元化合物。

5. 发明申请

WO2005063010A1 A NOVEL USE OF NEUROACTIVE COMPOUNDS 审中-公开
标题翻译：神经元化合物的新用途
公开(公告)号：WO2005063010A1
公开(公告)日：2005-07-14
申请号：PCT/IN2003/000418
申请日：2003-12-30
申请人： COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH , SHARMA, Abhay
发明人： SHARMA, Abhay
IPC分类号： A01K67/033
CPC分类号： A61K31/44 , A01K2227/706 , A01K2267/0356 , A61K31/47
摘要： The invention relates to a novel use of neuroactive compounds by treating the fruitfly Drosophila melanogaster adult males with fly medium containing either of the neuroactive compounds strychnine, pentylenetetrazol, tetraethylammonium chloride, lithium carbonate and nicotine, crossing the drug treated males with untreated females to obtain progenies and self-crossing the progenies to obtain grand progenies, observing the locomotor behavior of the parents and their progenies and grand progenies in terms of height climbed in a negative geotaxis assay, wherein an altered height climbed by parents and their progenies and grand progenies, compared to those of normally fed males, demonstrates that the neuroactive compounds produce inheritable behavioral change.
摘要翻译：本发明涉及通过用含有神经活性化合物士的宁，戊四氮，四乙基氯化铵，碳酸锂和尼古丁的飞行培养基处理果蝇果蝇黑腹果蝇成年雄性的新型用途，将药物治疗的雄性与未处理的雌性杂交，以获得后代并自行跨越后代获得大型后代，观察父母及其子代和大后代在负性地质学测定中的爬升高度的运动行为，其中由父母及其后代和大后代爬升的高度相比较对于正常饲养的雄性，表明神经活性化合物产生可遗传的行为变化。

6. 发明申请

WO2008041244A3 A METHOD FOR THE IDENTIFICATION OF POTENTIAL BIOMARKERS AND DRUG TARGETS IN BRAIN PLASTICITY RELATED DISORDERS 审中-公开
标题翻译：鉴定潜在生物标志物和大脑相关疾病中药物靶标的方法
公开(公告)号：WO2008041244A3
公开(公告)日：2008-07-31
申请号：PCT/IN2007000452
申请日：2007-10-01
申请人： COUNCIL SCIENT IND RES , SHARMA ABHAY , SINGH PRIYANKA , FARHAN MD
发明人： SHARMA ABHAY , SINGH PRIYANKA , FARHAN MD
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/158
摘要： The invention relates to identification of potential biomarkers and drug targets in brain plasticity related disorders. In particular, the invention describes a system level model of brain plasticity related disorders in the fruit fly Drosophila
摘要翻译：本发明涉及鉴定脑可塑性相关疾病中的潜在生物标志物和药物靶标。特别地，本发明描述了果蝇中脑可塑性相关疾病的系统级模型

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