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1. 发明申请

WO2016151136A1 DENTAL COMPOSITES COMPRISING POROUS FILLERS 审中-公开
标题翻译：包含多孔填料的牙科复合材料
公开(公告)号：WO2016151136A1
公开(公告)日：2016-09-29
申请号：PCT/EP2016/056708
申请日：2016-03-25
申请人： SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT
发明人： HALLAY, Franck , COLON, Pierre , RICHARD, Gilles , BOIS, Laurence , BRIOUDE, Arnaud , GROSGOGEAT, Brigitte
IPC分类号： A61K6/00 , A61K6/083 , C08L33/14
CPC分类号： A61K6/0073 , A61K6/0017 , A61K6/083 , C08F230/08 , C08L33/14
摘要： The invention relates to a composition in the dental field. Especially, the invention relates to a composition resulting from the mixture of: - a resin matrix; and - a filler blend comprising at least one primary filler and at least one porous filler. The invention also relates to a method for preparing said dental composition and its uses in the dental field. The invention also relates to a process for manufacturing a composite comprising the preparation of the composition of the invention. The present invention also relates to a kit of parts for the preparation of a composition suitable in dentistry comprising in a first container a resin matrix according to the invention and in a second container a filler blend comprising at least one primary filler and at least one porous filler.
摘要翻译：本发明涉及牙科领域中的组合物。特别地，本发明涉及由以下混合物得到的组合物： - 树脂基质; 和 - 包含至少一种主填料和至少一种多孔填料的填料共混物。本发明还涉及一种在牙科领域中制备所述牙科用组合物及其用途的方法。本发明还涉及制备包含本发明组合物的复合材料的方法。本发明还涉及一种用于制备适合于牙科的组合物的试剂盒，其包括在第一容器中，根据本发明的树脂基质和在第二容器中的填料共混物，其包含至少一种主填料和至少一种多孔填料。

2. 发明申请

WO2021019096A1 COMPLEMENT ACTIVE FRAGMENT-LOADED THREE-DIMENSIONAL BIOMATERIAL FOR DENTAL AND/OR OTHER TISSUE REGENERATION 审中-公开
公开(公告)号：WO2021019096A1
公开(公告)日：2021-02-04
申请号：PCT/EP2020/071734
申请日：2020-07-31
申请人： SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT , UNIVERSITÉ D'AIX MARSEILLE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人： ABOUT, Imad , RICHARD, Gilles , BERGMANN, Madison , JEANNEAU, Charlotte , DJOUDI, Mounir
IPC分类号： A61L27/18 , A61L27/24 , A61L27/54 , A61L27/56
摘要： The present invention relates to a three-dimensional biomaterial comprising particles encapsulating at least one complement active fragment dispersed therein. The invention also refers to a process of manufacturing of said biomaterial. The biomaterial is useful for tissue regeneration, especially with regards to dental pulp, dentin, periodontal and gingival tissues, as well as bones tissues.

3. 发明申请

WO2018189384A1 CONNECTIVE TISSUES, SUCH AS BONE, DENTIN OR PULP, REGENERATIVE MATERIAL COMPRISING CALCIUM SILICATE 审中-公开
公开(公告)号：WO2018189384A1
公开(公告)日：2018-10-18
申请号：PCT/EP2018/059563
申请日：2018-04-13
申请人： SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT , UNIVERSITÉ PARIS DESCARTES - PARIS V , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITÉ PIERRE ET MARIE CURIE - PARIS 6 (UPMC)
发明人： BERES, Fleur , RICHARD, Gilles , DESSOMBZ, Arnaud , SIMON, Stéphane , ISAAC, Juliane
IPC分类号： A61L27/44
摘要： The present invention relates to a regenerative material in the connective tissues (such as bone, dentin or pulp) regeneration field. More precisely, the present invention relates to a connective tissue regenerative material, preferably a bone, dentin or pulp regenerative material, comprising: - a porous polymer matrix having interconnected pores; and - non-hydrated calcium silicate particles; wherein: said polymer matrix is anhydrous; said non-hydrated calcium silicate particles have a dso granulometry, preferably ranging from 0.05 iim to less than the average diameter size of the pores of the matrix; and said non-hydrated calcium silicate particles being coated on the inside walls of the pores of the matrix. The present invention also relates to method for preparing said connective tissue regenerative material. The present invention also concerns uses of said regenerative materials, such as for example in the dental field; especially, for providing regenerative materials with improved biomechanical and osteoinductive properties (i.e. good migration, adhesion and proliferation of cells; enhanced mechanical properties; and optimal and controlled biodegradability).

4. 发明申请

WO2022184931A1 CALCIUM SILICATE-BASED DENTAL COMPOSITION LEADING TO IMPROVED PROPERTIES 审中-公开
公开(公告)号：WO2022184931A1
公开(公告)日：2022-09-09
申请号：PCT/EP2022/055648
申请日：2022-03-04
申请人： SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT
发明人： DJOUDI, Mounir , RICHARD, Gilles , LEROUX, Esther
IPC分类号： A61K6/56 , A61K6/78 , A61K6/853 , A61K6/856 , A61K6/873 , A61K6/876 , C04B28/18 , C04B111/00
摘要： The present invention relates to a dental composition comprising calcium silicate, calcium carbonate, and at least one pozzolanic material, which is useful to prepare a hardened dental material with improved properties. The invention further relates to a kit comprising the dental composition of the invention for preparing a hardened dental material, to a medical device comprising said kit and to the use of the dental material for treating the crown of a tooth and/or the root of a tooth.

5. 发明申请

WO2021089798A1 NON-BREAKING FILAMENT FOR SHAPING BONE AND DENTAL SUBSTITUTES 审中-公开
公开(公告)号：WO2021089798A1
公开(公告)日：2021-05-14
申请号：PCT/EP2020/081320
申请日：2020-11-06
申请人： SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT
发明人： RICHARD, Gilles , PHAM, Dai
IPC分类号： A61L27/44
摘要： The present invention relates to the field of materials, preferably materials for additive manufacturing. More precisely, the present invention relates to a non-breaking filament, preferably for 3D printing bone substitutes, said filament comprising 50% to 99% in weight to the total weigh of the filament (w/w) of a polymeric matrix and 1% to 50% w/w of tricalcium silicate. The present invention also relates to method and composition for preparing said filament. The present invention also concerns uses of said filament, such as for example in the dental field; especially, for providing suitable bone and dental substitutes.

6. 发明申请

WO2021013752A1 CARTRIDGE FOR DISPENSING A MATERIAL 审中-公开
公开(公告)号：WO2021013752A1
公开(公告)日：2021-01-28
申请号：PCT/EP2020/070358
申请日：2020-07-17
申请人： SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT
发明人： MARIE, Olivier , RICHARD, Gilles , CO, Clémence , ARTAUD, Laurent , CHABRIER, Olivier
IPC分类号： A61C5/64 , A61J1/06 , A61M5/24 , A61M5/28 , A61M5/31
摘要： This cartridge (1), intended for the dispensing of a material, comprises: - a sleeve (2) having a longitudinal axis (X-X') and comprising a distal wall (22) provided with a dispensing hole (23); - a barrel (3) defining a chamber (35) configured to receive the material, the barrel (3) comprising a proximal open end and a breakable distal wall (39) at its distal end, the barrel (3) being configured to move in the sleeve (2) along the longitudinal axis (X-X') between a first position, in which the distal wall (39) of the barrel (3) is at a distance (e 1 ) from the distal wall (22) of the sleeve (2), and a second position, in which a sealing portion of the distal wall (39) of the barrel (3) is in contact with an inner surface of the distal wall (22) of the sleeve (2); - a piston (4, 5) configured to seal the chamber (35) of the barrel (3), the piston (4, 5) comprising a plate (47) configured to move in sealing engagement in the chamber (35) of the barrel (3); - wherein the sleeve (2) comprises an internal piercing element (29) in the vicinity of the dispensing hole (23), the piercing element (29) being configured to break the distal wall (39) of the barrel (3) upon transition of the barrel (3) from the first position to the second position; and - the sleeve (2) comprises an annular cavity (24) around the piercing element (29), the annular cavity (24) being delimited peripherally by a beveled inner surface complementary to a corresponding beveled outer surface of the barrel (3).

7. 发明申请

WO2021009369A1 DENTAL HYDRAULIC CEMENT COMPRISING ULTRAFINE CALCIUM SILICATE PARTICLES HAVING FAST HARDENING AND SUITABLE MECHANICAL PROPERTIES 审中-公开
公开(公告)号：WO2021009369A1
公开(公告)日：2021-01-21
申请号：PCT/EP2020/070350
申请日：2020-07-17
申请人： SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT
发明人： RICHARD, Gilles , MARIE, Olivier , CO, Clémence
IPC分类号： C04B7/52 , C04B28/02 , C04B28/04 , C04B14/04 , C04B28/34
摘要： The present invention relates to the provision of a dental restoration material, from a dental hydraulic cement comprising ultrafine calcium silicate (UCS) particles, in presence of a limited amount of water, so that the hydraulic cement fast hardens while providing a material having suitable mechanical properties for dental restoration, and especially a high compressive strength.

8. 发明申请

WO2013041709A1 WEAR RESISTANT DENTAL COMPOSITION 审中-公开
标题翻译：耐磨牙膏组合物
公开(公告)号：WO2013041709A1
公开(公告)日：2013-03-28
申请号：PCT/EP2012/068711
申请日：2012-09-21
申请人： SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT , RICHARD, Gilles , MARIE, Olivier , BAFOUNGUISSA, Laurianne
发明人： RICHARD, Gilles , MARIE, Olivier , BAFOUNGUISSA, Laurianne
IPC分类号： A61K6/00
CPC分类号： A61K6/0047 , A61K6/0073 , A61K6/0091 , A61K6/0612 , C04B7/345 , C04B14/26 , C04B14/301 , C04B14/38 , C04B16/00 , C04B16/06 , C04B16/08 , C04B22/064
摘要： The present invention relates to a solid composition comprising: a calcium silicate powder, a set accelerator in the form of a powder, a reinforcing filler in a solid form, a radio-opacifying agent in a solid form, at least one complementary ingredient selected from solid fibers or solid porous fillers, optionally a water-reducing agent in a solid form, and optionally solid pigments. The present invention also relates to a kit of parts for the preparation of a composition suitable for use in dentistry comprising in a first container a solid phase including the solid composition according to the invention, and in a second container an aqueous phase. The present invention also relates to a kit of parts for the preparation of a composition suitable for use in dentistry comprising a container, said container comprising at least two cells, the first cell comprising a solid phase including the solid composition of the invention and the second cell comprising an aqueous phase. The present invention also relates to a method for preparing a dental cement, including mixing the solid composition of the invention with an aqueous phase and to resulting dental cement.
摘要翻译：固体组合物本发明涉及一种固体组合物，其包括：硅酸钙粉末，粉末形式的凝固加速剂，固体形式的增强填料，固体形式的放射性不透明剂，至少一种互补成分，固体纤维或固体多孔填料，任选的固体形式的减水剂，以及任选的固体颜料。本发明还涉及一种用于制备适用于牙科的组合物的试剂盒，其包括在第一容器中，包含根据本发明的固体组合物的固相和在第二容器中的水相。本发明还涉及一种用于制备适用于牙科的组合物的试剂盒，其包含容器，所述容器包含至少两个细胞，所述第一细胞包含固相，其包含本发明的固体组合物和第二包含水相的细胞。本发明还涉及一种制备牙科粘固剂的方法，包括将本发明的固体组合物与水相混合，得到牙科粘固剂。

9. 发明申请

WO2012065946A1 ENDODONTIC SEALING COMPOSITION 审中-公开
标题翻译：内接式密封组合物
公开(公告)号：WO2012065946A1
公开(公告)日：2012-05-24
申请号：PCT/EP2011/070040
申请日：2011-11-14
申请人： SEPTODONT ou SEPTODONT SAS ou SPECIALITES SEPTODONT , RICHARD, Gilles , MARIE, Olivier
发明人： RICHARD, Gilles , MARIE, Olivier
IPC分类号： A61K6/00 , A61K6/06 , C09K3/00
CPC分类号： A61K6/0073 , A61K6/0091 , A61K6/0625 , A61K6/0668 , A61K6/0675 , A61K6/0681 , A61K6/0038 , C08L29/04 , C08L31/04 , C08L33/08 , C08L33/10 , C08L33/14 , C08L5/04 , C08L83/04 , C08L23/20 , C08L7/00 , A61K6/0835 , C08L39/06 , A61K6/0035
摘要： This invention relates to a composition resulting from the mixture of a solid phase, comprising at least one calcium derivative powder in association with at least one radioopacifier and at least one polymer and optionally at least one non-radioopaque filler, all in powder form; and aqueous phase comprising water, at least one water-reducing agent, and at least one set accelerator; the ratio of solid phase to liquid phase ranging from 1.0 to 2.5, preferably from 1.5 to 2.2, more preferably from 2 to 2.15; said composition having a compressive strength of less than 40 MPa, preferably ranging from 1 to 15 MPa, preferably ranging from about 3 to about 12 MPa; this invention also relates to a kit and a method for the manufacture of the composition, and to a method for treating or retreating a canal root.
摘要翻译：本发明涉及由固相混合物组成的组合物，其包含至少一种与至少一种放射性光聚合剂结合的钙衍生物粉末和至少一种粉末形式的聚合物和任选的至少一种非辐射光斑填充剂; 和含有水，至少一种减水剂和至少一种凝固促进剂的水相; 固相与液相的比例为1.0至2.5，优选为1.5至2.2，更优选为2至2.15; 所述组合物的抗压强度小于40MPa，优选为1至15MPa，优选为约3至约12MPa; 本发明还涉及一种用于制备组合物的试剂盒和方法，以及用于治疗或后退管根的方法。

10. 发明申请

WO2022184932A1 CALCIUM SILICATE-BASED HYDRAULIC CEMENT TO FORM A COMPOSITE MATERIAL HAVING REINFORCING PROPERTIES 审中-公开
公开(公告)号：WO2022184932A1
公开(公告)日：2022-09-09
申请号：PCT/EP2022/055649
申请日：2022-03-04
申请人： SEPTODONT OU SEPTODONT SAS ou SPECIALITES SEPTODONT
发明人： DJOUDI, Mounir , RICHARD, Gilles , ARTAUD, Laurent
IPC分类号： C04B28/18 , C04B14/28 , C04B28/04
摘要： The present invention relates to the field of hydraulic cements and hardened materials obtained after hydration of said hydraulic cements, especially cements useful in the medical field such as dental cements. In particular, the present invention provides a hydraulic cement comprising calcium silicate particles and calcium carbonate particles having specific particles sizes. The hydration of the hydraulic cement of the invention enables to provide a hardened composite material with reinforcing properties, comprising calcium silicate particles dispersed in a solid dispersant phase including calcium silicate hydrates (CSH) and porous intergranular areas comprising insoluble calcium carbonate particles having a d50 granulometry ranging from 1 nm to 1500 nm.

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