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1. 发明申请

WO2007100585A2 DUAL LUMEN ASPIRATION CATHETER SYSTEM 审中-公开
标题翻译：双龙吸气导管系统
公开(公告)号：WO2007100585A2
公开(公告)日：2007-09-07
申请号：PCT/US2007/004523
申请日：2007-02-16
申请人： POSSIS MEDICAL, INC. , LE, Hieu, V. , SCHROM, Michael, P. , WONG, Diana, L. , MATSON, Kyle, R. , SWANSON, Dean, A. , GRANT, Kathleen, C. , KLEE, James, T.
发明人： LE, Hieu, V. , SCHROM, Michael, P. , WONG, Diana, L. , MATSON, Kyle, R. , SWANSON, Dean, A. , GRANT, Kathleen, C. , KLEE, James, T.
CPC分类号： A61M25/008 , A61B17/22 , A61M25/0032 , A61M25/0068 , A61M2025/0081
摘要： A dual lumen aspiration catheter system with an aspiration catheter, a hub and a flexible strain relief, and a suction assembly. The aspiration catheter includes multiple successively connected flexible tubular components each increasing in relative flexibility in the distal direction, the most proximal tubular component connectingly extending from the hub and through the flexible strain relief. The tubular components of the aspiration catheter include, in order proximally to distally, a composite tube, an intermediate tube, a dual lumen tube, and a flexible tip tube. The dual lumen tube includes eccentrically co-located large and small tubular portions forming eccentrically co-located large and small lumens to provide a minimum cross section. The distal end of the dual lumen tube includes a convex beveled edge. The convex beveled edge and the flexible tip tube singly or jointly inflict minimal traumatic contact with a vessel wall when urged along a tortuous vascular path.
摘要翻译：具有抽吸导管，轮毂和柔性应变消除装置的双腔抽吸导管系统和抽吸组件。抽吸导管包括多个连续连接的柔性管状部件，每个柔性管状部件在远端方向上相对柔性增加，最近端的管状部件从轮毂连接延伸并穿过柔性应变消除部。抽吸导管的管状部件按照向远端方向依次包括复合管，中间管，双腔管和柔性末端管。双腔管包括偏心地共同定位的大和小管状部分，形成偏心共同定位的大小腔，以提供最小横截面。双腔管的远端包括凸出的斜边缘。当沿着曲折的血管路径被推动时，凸出的斜边缘和柔性尖端管单独或联合地与血管壁产生最小的创伤性接触。

2. 发明申请

WO2005011806A1 SYSTEM AND METHOD FOR PROVIDING A MEDICAL LEAD BODY HAVING DUAL CONDUCTOR LAYERS 审中-公开
标题翻译：用于提供具有双导电层的医用铅体的系统和方法
公开(公告)号：WO2005011806A1
公开(公告)日：2005-02-10
申请号：PCT/US2004/024553
申请日：2004-07-28
申请人： MICRONET MEDICAL, INC. , SCHROM, Michael, P. , LEHMAN, Charles, F. , SCHROM, Mark, G.
发明人： SCHROM, Michael, P. , LEHMAN, Charles, F. , SCHROM, Mark, G.
IPC分类号： A61N1/05
CPC分类号： A61N1/06 , A61N1/05 , A61N1/0551
摘要： An implantable medical lead 100 and lead body 120, method of manufacturing the same, and a system and method for stimulating a portion of a body is disclosed. In one advantageous embodiment, a lead body assembly 115 is formed by preparing a first layer unitary body 500 comprising a first plurality of conductors 420. An inner layer of extrusion material 610 is placed on the first layer unitary body 500. A second plurality of conductors 620 coated with extrusion material 630 is placed on the inner layer 610. An outer layer of extrusion material 640 is placed over the second plurality of conductors 620. Heat shrink tubing is placed over the assembly and the assembly is heated to melt the extrusion material. The extrusion material (610, 630, 640) is compressed around the conductors 620. The assembly is cooled and the heat shrink tubing is removed. The solidified extrusion material forms a protective wall 710 that encapsulates the first and second plurality of conductors (420, 620) in the lead body 120.
摘要翻译：公开了一种可植入医疗用引线100及引线本体120及其制造方法，以及用于刺激身体的一部分的系统及方法。在一个有利的实施例中，通过制备包括第一多个导体420的第一层整体500形成引线本体组件115.挤出材料610的内层被放置在第一层整体500上。第二多个导体 620涂覆有挤出材料630放置在内层610上。挤出材料640的外层放置在第二多个导体620上。热收缩管放置在组件上方，并且组件被加热以熔化挤出材料。挤出材料（610,630,640）围绕导体620被压缩。组件被冷却并且热收缩管被去除。固化的挤出材料形成将引导体120中的第一和第二多个导体（420,620）封装的保护壁710。

3. 发明申请

WO2006107343A2 RAPID EXCHANGE FLUID JET THROMBECTOMY DEVICE AND METHOD 审中-公开
标题翻译：快速交换流体喷射式液晶显示装置及方法
公开(公告)号：WO2006107343A2
公开(公告)日：2006-10-12
申请号：PCT/US2005/041412
申请日：2005-11-12
申请人： POSSIS MEDICAL, INC. , BONNETTE, Michael, J. , SCHROM, Michael, P. , LE, Hieu, V.
发明人： BONNETTE, Michael, J. , SCHROM, Michael, P. , LE, Hieu, V.
IPC分类号： A61B17/32
CPC分类号： A61B17/32037 , A61B17/22 , A61B17/3203 , A61B2017/00292 , A61B2017/00778 , A61B2017/22041 , A61B2090/034
摘要： A rapid exchange fluid jet thrombectomy device having a streamlined manifold and a catheter having multiple tubular segments where each tubular segment increases in flexibility in a distal direction. Torque response and pushability is enhanced by the arrangement of a proximally located tubular segment composed of a polymer-jacketed spiral metal tube in combination with an intermediate tubular section and a distal tubular section each having different degrees of flexibility. A guidewire tube exit region is provided where the intermediate tubular section joins the distal tubular section for over-the-wire guidewire usage. The polymer-jacketed spiral metal tube can extend along a partial or full length of the catheter and can include a basic continuous spiral cut which has regions of constant pitch or which has progressively decreasing pitch, or in the alternative, can include an interlocking spiral cut having constant pitch regions or progressively decreasing pitch.
摘要翻译：具有流线型歧管的快速交换流体喷射血栓切除装置和具有多个管状区段的导管，其中每个管状区段在远端方向上的柔性增加。通过由聚合物夹套的螺旋金属管组成的近端定位的管状部分与中间管状部分和每个具有不同柔性程度的远端管状部分的组合来增强扭矩响应和推动性。提供导丝管出口区域，其中中间管状部分连接远端管状部分用于线上导丝使用。聚合物套管的螺旋金属管可以沿着导管的部分或全长延伸，并且可以包括具有恒定节距的区域或具有逐渐减小的间距的基本连续的螺旋切口，或者替代地，可以包括互锁的螺旋切口具有恒定的音调区域或逐渐减小音调。

4. 发明申请

WO2007100585A3 DUAL LUMEN ASPIRATION CATHETER SYSTEM 审中-公开
标题翻译：双龙吸气导管系统
公开(公告)号：WO2007100585A3
公开(公告)日：2008-05-02
申请号：PCT/US2007004523
申请日：2007-02-16
申请人： POSSIS MEDICAL INC , LE HIEU V , SCHROM MICHAEL P , WONG DIANA L , MATSON KYLE R , SWANSON DEAN A , GRANT KATHLEEN C , KLEE JAMES T
发明人： LE HIEU V , SCHROM MICHAEL P , WONG DIANA L , MATSON KYLE R , SWANSON DEAN A , GRANT KATHLEEN C , KLEE JAMES T
IPC分类号： A61M25/14
CPC分类号： A61M25/008 , A61B17/22 , A61M25/0032 , A61M25/0068 , A61M2025/0081
摘要： A dual lumen aspiration catheter system with an aspiration catheter, a hub and a flexible strain relief, and a suction assembly. The aspiration catheter includes multiple successively connected flexible tubular components each increasing in relative flexibility in the distal direction, the most proximal tubular component connectingly extending from the hub and through the flexible strain relief. The tubular components of the aspiration catheter include, in order proximally to distally, a composite tube, an intermediate tube, a dual lumen tube, and a flexible tip tube. The dual lumen tube includes eccentrically co-located large and small tubular portions forming eccentrically co-located large and small lumens to provide a minimum cross section. The distal end of the dual lumen tube includes a convex beveled edge. The convex beveled edge and the flexible tip tube singly or jointly inflict minimal traumatic contact with a vessel wall when urged along a tortuous vascular path.
摘要翻译：具有抽吸导管，轮毂和柔性应变消除装置的双腔抽吸导管系统和抽吸组件。抽吸导管包括多个连续连接的柔性管状部件，每个柔性管状部件在远端方向上相对柔性增加，最近端的管状部件从轮毂连接延伸并穿过柔性应变消除部。抽吸导管的管状部件按照向远端方向依次包括复合管，中间管，双腔管和柔性末端管。双腔管包括偏心地共同定位的大和小管状部分，形成偏心共同定位的大小腔，以提供最小横截面。双腔管的远端包括凸出的斜边缘。当沿着曲折的血管路径被推动时，凸出的斜边缘和柔性尖端管单独或联合地与血管壁产生最小的创伤性接触。

5. 发明申请

WO2006107343A3 RAPID EXCHANGE FLUID JET THROMBECTOMY DEVICE AND METHOD 审中-公开
标题翻译：快速交换流体喷射式液晶显示装置及方法
公开(公告)号：WO2006107343A3
公开(公告)日：2007-11-08
申请号：PCT/US2005041412
申请日：2005-11-12
申请人： POSSIS MEDICAL INC , BONNETTE MICHAEL J , SCHROM MICHAEL P , LE HIEU V
发明人： BONNETTE MICHAEL J , SCHROM MICHAEL P , LE HIEU V
IPC分类号： A61B17/32 , A61B17/00 , A61B17/20 , A61B17/22 , A61B19/00 , A61M25/00
CPC分类号： A61B17/32037 , A61B17/22 , A61B17/3203 , A61B2017/00292 , A61B2017/00778 , A61B2017/22041 , A61B2090/034
摘要： A rapid exchange fluid jet thrombectomy device having a streamlined manifold and a catheter having multiple tubular segments where each tubular segment increases in flexibility in a distal direction. Torque response and pushability is enhanced by the arrangement of a proximally located tubular segment composed of a polymer-jacketed spiral metal tube in combination with an intermediate tubular section and a distal tubular section each having different degrees of flexibility. A guidewire tube exit region is provided where the intermediate tubular section joins the distal tubular section for over-the-wire guidewire usage. The polymer-jacketed spiral metal tube can extend along a partial or full length of the catheter and can include a basic continuous spiral cut which has regions of constant pitch or which has progressively decreasing pitch, or in the alternative, can include an interlocking spiral cut having constant pitch regions or progressively decreasing pitch.
摘要翻译：具有流线型歧管的快速交换流体喷射血栓切除装置和具有多个管状区段的导管，其中每个管状区段在远端方向上的柔性增加。通过由聚合物夹套的螺旋金属管组成的近端定位的管状部分与中间管状部分和每个具有不同柔性程度的远端管状部分的组合来增强扭矩响应和推动性。提供导丝管出口区域，其中中间管状部分连接远端管状部分以用于线上导丝使用。聚合物套管的螺旋金属管可以沿着导管的部分或全长延伸，并且可以包括具有恒定节距或具有逐渐减小的间距的区域的基本连续螺旋切口，或者替代地，可以包括互锁螺旋切割具有恒定的音调区域或逐渐减小音调。

6. 发明申请

WO2006065424A2 ENHANCED CROSS STREAM MECHANICAL THROMBECTOMY CATHETER WITH BACKLOADING MANIFOLD 审中-公开
标题翻译：带有卸载歧管的增强型十字机械液压导管
公开(公告)号：WO2006065424A2
公开(公告)日：2006-06-22
申请号：PCT/US2005/041409
申请日：2005-11-12
申请人： POSSIS MEDICAL, INC. , BONNETTE, Michael, J. , THOR, Eric, J. , SCHROM, Michael, P.
发明人： BONNETTE, Michael, J. , THOR, Eric, J. , SCHROM, Michael, P.
IPC分类号： A61M31/00
CPC分类号： A61B17/32037 , A61B17/22 , A61B2017/22079 , A61B2017/22084 , A61B2217/005 , A61M25/0029 , A61M25/0032 , A61M25/0045 , A61M25/005 , A61M25/007 , A61M2025/0034 , Y10T29/49826
摘要： An enhanced cross stream mechanical thrombectomy catheter with backloading manifold having a distal end with outflow and inflow orifices at one side for producing concentrated cross stream jet flow for selective and concentrated thrombus ablation during thrombectomy procedures. The invention provides for suitable distancing of high powered ablation or suction forces from the near walls of the vasculature. Cross stream flow emanating from the one side of the distal end of the catheter resultantly urges the distal end of the catheter and thus the opposing non-orificed side of the distal end of the catheter toward and against the vascular wall to inhibit contact of the inflow orifice with the vascular wall. Features of the invention include a geometrically configured insert to facilitate the backloading or exchange of guidewires.
摘要翻译：具有后支管道的增强的交叉流机械性血栓切除术导管，其具有在一侧具有流出和流入孔的远端，用于在血栓切除术过程中产生用于选择性和集中血栓消融的浓缩的交叉流射流。本发明提供从脉管系统的近壁适当地间隔大功率消融或吸力。从导管的远端的一侧发出的交叉流流动导致导管的远端，并因此促使导管的远端的相对的未通气的侧面朝向和抵靠血管壁，以阻止流入物的接触孔与血管壁。本发明的特征包括几何构造的插入件，以便于引导线的后退或更换。

7. 发明申请

WO2006065424A3 ENHANCED CROSS STREAM MECHANICAL THROMBECTOMY CATHETER WITH BACKLOADING MANIFOLD 审中-公开
标题翻译：增强十字流机械切除导管带后向负载
公开(公告)号：WO2006065424A3
公开(公告)日：2006-09-21
申请号：PCT/US2005041409
申请日：2005-11-12
申请人： POSSIS MEDICAL INC , BONNETTE MICHAEL J , THOR ERIC J , SCHROM MICHAEL P
发明人： BONNETTE MICHAEL J , THOR ERIC J , SCHROM MICHAEL P
IPC分类号： A61M31/00
CPC分类号： A61B17/32037 , A61B17/22 , A61B2017/22079 , A61B2017/22084 , A61B2217/005 , A61M25/0029 , A61M25/0032 , A61M25/0045 , A61M25/005 , A61M25/007 , A61M2025/0034 , Y10T29/49826
摘要： An enhanced cross stream mechanical thrombectomy catheter with backloading manifold having a distal end with outflow and inflow orifices at one side for producing concentrated cross stream jet flow for selective and concentrated thrombus ablation during thrombectomy procedures. The invention provides for suitable distancing of high powered ablation or suction forces from the near walls of the vasculature. Cross stream flow emanating from the one side of the distal end of the catheter resultantly urges the distal end of the catheter and thus the opposing non-orificed side of the distal end of the catheter toward and against the vascular wall to inhibit contact of the inflow orifice with the vascular wall. Features of the invention include a geometrically configured insert to facilitate the backloading or exchange of guidewires.
摘要翻译：一种增强的交叉流机械血栓切除导管，其带有背部加载歧管，其远端在一侧具有流出口和流入口，用于在血栓切除术过程中产生用于选择性和浓缩血栓消融的集中横流射流。本发明提供了来自脉管系统近壁的高功率消融或吸力的适当的间隔。从导管的远端的一侧发出的叉流结果促使导管的远端以及因此导管的远端的相对的非孔侧朝向并抵靠血管壁以阻止流入物的接触孔与血管壁。本发明的特征包括几何构造的插入物以促进导线的回填或交换。

8. 发明申请

WO2005011807A1 SYSTEM AND METHOD FOR PROVIDING A MEDICAL LEAD BODY 审中-公开
标题翻译：用于提供医疗领导体的系统和方法
公开(公告)号：WO2005011807A1
公开(公告)日：2005-02-10
申请号：PCT/US2004/024582
申请日：2004-07-28
申请人： MICRONET MEDICAL, INC. , SCHROM, Michael, P. , LEHMAN, Charles, F. , SCHROM, Mark, G.
发明人： SCHROM, Michael, P. , LEHMAN, Charles, F. , SCHROM, Mark, G.
IPC分类号： A61N1/05
CPC分类号： A61N1/06 , A61N1/05
摘要： An implantable lead 100 and lead body 120, method of manufacturing the same, and a system and method for stimulating a portion of a body is disclosed. In one advantageous embodiment, a lead body assembly 115 is formed by placing an inner layer of extrusion material 410 on a mandrel, wrapping a plurality of conductors 420 coated with extrusion material 430 around the inner layer 410, and placing an outer layer of extrusion material 440 over the plurality of conductors 420. Heat shrink tubing is placed over the lead body assembly 115 and the lead body assembly 115 is heated to melt the extrusion material (410, 430, 440). The melted extrusion material is compressed around the plurality of conductors 420. The assembly is then cooled and the heat shrink tubing is removed. The solidified extrusion material forms a protective wall 510 that encapsulates the plurality of conductors 420 in the lead body 120.
摘要翻译：公开了可植入引线100和引线主体120及其制造方法，以及用于刺激身体的一部分的系统和方法。在一个有利的实施例中，通过将挤压材料410的内层放置在心轴上，将包覆挤压材料430的多个导体420缠绕在内层410周围并且放置挤出材料外层多个导体420中的多个导线420.热收缩管放置在引线主体组件115上方，并且引线主体组件115被加热以熔化挤出材料（410,430,440）。熔融的挤出材料围绕多个导体420被压缩。然后将组件冷却并除去热收缩管。固化的挤出材料形成将多个导体420封装在引线主体120中的保护壁510。

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