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1. 发明申请

WO2006071255A2 BACTERIAL REPLICATION SYSTEMS AND METHODS 审中-公开
标题翻译：细菌再生系统和方法
公开(公告)号：WO2006071255A2
公开(公告)日：2006-07-06
申请号：PCT/US2005/015548
申请日：2005-04-26
申请人： REPLIDYNE, INC. , JARVIS, Thale Cross , MCHENRY, Charles S. , JANJIC, Nebojsa , DALLMANN, Garry , BULLARD, James M. , BELL, Stacie , SANDERS, Glenn , DEAN, Frank
发明人： JARVIS, Thale Cross , MCHENRY, Charles S. , JANJIC, Nebojsa , DALLMANN, Garry , BULLARD, James M. , BELL, Stacie , SANDERS, Glenn , DEAN, Frank
CPC分类号： C07K14/21 , C07K14/195 , C07K14/31 , C12N15/63 , C12N15/69 , C12N15/70
摘要： Reconstituted bacterial replication assemblies and methods for their use are provided.
摘要翻译：提供重组的细菌复制组件及其使用方法。

2. 发明申请

WO2012174496A9 METHOD FOR PURIFICATION AND IDENTIFICATION OF SPERM CELLS 审中-公开
标题翻译：纯化和鉴定精细细胞的方法
公开(公告)号：WO2012174496A9
公开(公告)日：2013-03-21
申请号：PCT/US2012042835
申请日：2012-06-15
申请人： SOMALOGIC INC , SANDERS GLENN , KATILIUS EVALDAS , GOLD LARRY
发明人： SANDERS GLENN , KATILIUS EVALDAS , GOLD LARRY
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12N5/061 , C12N15/115 , C12N2310/16 , C12N2320/10
摘要： The present disclosure describes the isolation, identification and purification of aptamers having sufficiently high affinity and specificity to capture and immobilize intact sperm cells in the presence of female epithelial cells and other non-sperm semen components. The present disclosure also describes affinity-based methods for the detection of sperm cells in test samples, including from forensic sample surrogates consisting of swab eluates containing a mixture of HeLa cells and sperm cells. The present disclosure describes methods for eluting sperm cell samples from swabs; methods for purifying sperm cells and methods for amplification and analysis of male DNA. The affinity-based system described herein is inexpensive, simple to use and easily implemented in forensic laboratories.
摘要翻译：本公开描述了具有足够高亲和力和特异性的适体的分离，鉴定和纯化，以在雌性上皮细胞和其他非精子精液组分存在下捕获和固定完整的精子细胞。本公开还描述了用于检测测试样品中的精细胞的基于亲和力的方法，所述方法包括由含有HeLa细胞和精子细胞的混合物的拭子洗脱物组成的法医样品替代物。本公开描述了用于从拭子洗脱精细胞样品的方法; 纯化精子细胞的方法以及扩增和分析雄性DNA的方法。此处描述的基于亲和力的系统价格便宜，易于使用并且易于在法医实验室中实施。

3. 发明申请

WO2012174496A2 METHOD FOR PURIFICATION AND IDENTIFICATION OF SPERM CELLS 审中-公开
标题翻译：稀释细胞的纯化和鉴定方法
公开(公告)号：WO2012174496A2
公开(公告)日：2012-12-20
申请号：PCT/US2012042835
申请日：2012-06-15
申请人： SOMALOGIC INC , SANDERS GLENN , KATILIUS EVALDAS , GOLD LARRY
发明人： SANDERS GLENN , KATILIUS EVALDAS , GOLD LARRY
IPC分类号： C12N5/076 , C07H21/00 , C07H21/04 , C12Q1/68 , C40B20/00
CPC分类号： C12N5/061 , C12N15/115 , C12N2310/16 , C12N2320/10
摘要： The present disclosure describes the isolation, identification and purification of aptamers having sufficiently high affinity and specificity to capture and immobilize intact sperm cells in the presence of female epithelial cells and other non-sperm semen components. The present disclosure also describes affinity-based methods for the detection of sperm cells in test samples, including from forensic sample surrogates consisting of swab eluates containing a mixture of HeLa cells and sperm cells. The present disclosure describes methods for eluting sperm cell samples from swabs; methods for purifying sperm cells and methods for amplification and analysis of male DNA. The affinity-based system described herein is inexpensive, simple to use and easily implemented in forensic laboratories.
摘要翻译：本公开描述了具有足够高的亲和性和特异性的适体的分离，鉴定和纯化，以在存在雌性上皮细胞和其它非精液精液组分的情况下捕获和固定完整精子细胞。本公开还描述了用于检测测试样品中的精子细胞的基于亲和性的方法，包括由包含HeLa细胞和精子细胞的混合物的拭子洗脱液组成的法医样品替代物。本公开描述了从拭子洗脱精子细胞样品的方法; 纯化精子细胞的方法和扩增和分析雄性DNA的方法。本文描述的基于亲和性的系统是廉价的，易于使用并且容易地在法医实验室中实施。

4. 发明申请

WO2006071255A3 BACTERIAL REPLICATION SYSTEMS AND METHODS 审中-公开
标题翻译：细菌复制系统和方法
公开(公告)号：WO2006071255A3
公开(公告)日：2007-09-13
申请号：PCT/US2005015548
申请日：2005-04-26
申请人： REPLIDYNE INC , JARVIS THALE CROSS , MCHENRY CHARLES S , JANJIC NEBOJSA , DALLMANN GARRY , BULLARD JAMES M , BELL STACIE , SANDERS GLENN , DEAN FRANK
发明人： JARVIS THALE CROSS , MCHENRY CHARLES S , JANJIC NEBOJSA , DALLMANN GARRY , BULLARD JAMES M , BELL STACIE , SANDERS GLENN , DEAN FRANK
IPC分类号： C12N9/12 , C07H21/02 , C07H21/04 , C12Q1/68
CPC分类号： C07K14/21 , C07K14/195 , C07K14/31 , C12N15/63 , C12N15/69 , C12N15/70
摘要： Reconstituted bacterial replication assemblies and methods for their use are provided.
摘要翻译：提供了重建的细菌复制组件及其使用方法。

5. 发明申请

WO2006071255A9 BACTERIAL REPLICATION SYSTEMS AND METHODS 审中-公开
标题翻译：细菌再生系统和方法
公开(公告)号：WO2006071255A9
公开(公告)日：2007-02-15
申请号：PCT/US2005015548
申请日：2005-04-26
申请人： REPLIDYNE INC , JARVIS THALE CROSS , MCHENRY CHARLES S , JANJIC NEBOJSA , DALLMANN GARRY , BULLARD JAMES M , BELL STACIE , SANDERS GLENN , DEAN FRANK
发明人： JARVIS THALE CROSS , MCHENRY CHARLES S , JANJIC NEBOJSA , DALLMANN GARRY , BULLARD JAMES M , BELL STACIE , SANDERS GLENN , DEAN FRANK
CPC分类号： C07K14/21 , C07K14/195 , C07K14/31 , C12N15/63 , C12N15/69 , C12N15/70
摘要： Reconstituted bacterial replication assemblies and methods for their use are provided.
摘要翻译：提供重组的细菌复制组件及其使用方法。

6. 发明申请

WO2005036575A3 MICRO-ELECTROMECHANICAL SWITCHING BACKPLANE 审中-公开
公开(公告)号：WO2005036575A3
公开(公告)日：2005-04-21
申请号：PCT/US2004/033281
申请日：2004-10-06
申请人： ROLLTRONICS CORPORATION , SAUVANTE, Michael, D. , PASCH, Nicholas, F. , SANDERS, Glenn, C.
发明人： SAUVANTE, Michael, D. , PASCH, Nicholas, F. , SANDERS, Glenn, C.
IPC分类号： G09G3/34 , G02B26/08
摘要： A low cost, scalable backplane for black and white or color optical displays comprises a multi-membrane plastic structure on which is printed or deposited row and column drivers to form a matrix of micro electromechanical (MEM) switches. Each switch controls the state of a pixel in the optical display device. Critical to successful long-term operation, the backplane includes the controlled application of voltages to each switch so that the display functions correctly and display life is maximized. The MEM switches include a substantially non-pliable membrane and a substantially flexible membrane both of which include electrodes that when energized will create electrostatic forces that attracts the flexible membrane to the non-pliable membrane. The MEM switches are manufactured in an array with a pitch that provides a sufficient number of switches to drive an optical display device and each switch may be latched to eliminate the need to constantly refresh the device.

7. 发明申请

WO2013022944A1 DYNAMIC SPINAL FIXATION SYSTEM, METHOD OF USE, AND SPINAL FIXATION SYSTEM ATTACHMENT PORTIONS 审中-公开
标题翻译：动态脊柱固定系统，使用方法和脊柱固定系统附件部分
公开(公告)号：WO2013022944A1
公开(公告)日：2013-02-14
申请号：PCT/US2012/049959
申请日：2012-08-08
申请人： REVIVO MEDICAL, LLC , LEDET, Eric H. , SANDERS, Glenn Patrick
发明人： LEDET, Eric H. , SANDERS, Glenn Patrick
IPC分类号： A61B17/70 , A61F2/44
CPC分类号： A61B17/7026 , A61B17/7004 , A61B17/7007 , A61B17/701 , A61B17/7011 , A61B17/7025 , A61B17/7028 , A61B17/7029 , A61B17/7059 , A61B17/8023 , A61B2017/00004 , A61F2/4455
摘要： Dynamic spinal fixation systems including a member, a first attachment portion, a second attachment portion, and an intermediate portion. The first attachment portion is attached at a superior end of the member and includes a first opening. The second attachment portion is attached at an inferior end of the member and includes a second opening. The intermediate portion connects the first and second attachment portions. The dynamic spinal fixation systems may also include a relief in at least one of the first opening and the second opening. The systems may also include a third attachment portion with a third opening and an intermediate portion with a first and a second elastic mechanism. The first elastic mechanism connects the first and third attachment portions and the second elastic mechanism connects the third and second attachment portions. Surgical methods for inserting the dynamic spinal fixation systems in a patient are also disclosed.
摘要翻译：动态脊柱固定系统，包括构件，第一附接部分，第二附接部分和中间部分。第一附接部分附接在构件的上端，并且包括第一开口。第二附接部分附接在构件的下端，并且包括第二开口。中间部分连接第一和第二附接部分。动态脊柱固定系统还可以包括在第一开口和第二开口中的至少一个中的浮雕。系统还可以包括具有第三开口的第三附接部分和具有第一和第二弹性机构的中间部分。第一弹性机构连接第一和第三附接部分，第二弹性机构连接第三和第二附接部分。还公开了将动态脊柱固定系统插入患者体内的手术方法。

8. 发明申请

WO2012174496A3 METHOD FOR PURIFICATION AND IDENTIFICATION OF SPERM CELLS 审中-公开
公开(公告)号：WO2012174496A3
公开(公告)日：2012-12-20
申请号：PCT/US2012/042835
申请日：2012-06-15
申请人： SOMALOGIC, INC. , SANDERS, Glenn , KATILIUS, Evaldas , GOLD, Larry
发明人： SANDERS, Glenn , KATILIUS, Evaldas , GOLD, Larry
IPC分类号： C12Q1/68 , C07H21/04
摘要： The present disclosure describes the isolation, identification and purification of aptamers having sufficiently high affinity and specificity to capture and immobilize intact sperm cells in the presence of female epithelial cells and other non-sperm semen components. The present disclosure also describes affinity-based methods for the detection of sperm cells in test samples, including from forensic sample surrogates consisting of swab eluates containing a mixture of HeLa cells and sperm cells. The present disclosure describes methods for eluting sperm cell samples from swabs; methods for purifying sperm cells and methods for amplification and analysis of male DNA. The affinity-based system described herein is inexpensive, simple to use and easily implemented in forensic laboratories.

9. 发明申请

WO2007072116A1 MEDICAL APPARATUS WITH IMPROVED USER INTERFACE 审中-公开
标题翻译：具有改进用户界面的医疗设备
公开(公告)号：WO2007072116A1
公开(公告)日：2007-06-28
申请号：PCT/IB2006/000203
申请日：2006-02-03
申请人： GAMBRO LUNDIA AB , RONCADI, Fabio , SALSA, Marco , MALAGOLI, Matteo , SANDERS, Glenn , WARNS, Gary
发明人： RONCADI, Fabio , SALSA, Marco , MALAGOLI, Matteo , SANDERS, Glenn , WARNS, Gary
IPC分类号： G06F19/00 , A61M1/16
CPC分类号： A61M1/16 , A61M1/1613 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , A61M2205/502 , A61M2205/505 , G06F19/00 , G06F19/3481 , G16H40/63 , Y10S210/929
摘要： A medical apparatus (1) comprises a control system allowing storage of a number of shaping profiles. Each shaping profile (38) is stored as a plurality of pairs (39, 40), including a shaping profile reference value and a time interval value. The reference value is represented as fraction, for instance a percentage, of the total weight loss the apparatus should achieve at the end of a treatment time. Each time interval value is represented either as fraction of the total treatment time or as a prefixed actual time interval. The control system calculates the actual weight loss rate versus time profile based on the desired total weight loss, on the desired total treatment time as well as on selected desired shaping profile.
摘要翻译：医疗设备（1）包括允许存储多个成形轮廓的控制系统。每个成形轮廓（38）被存储为多对（39,40），包括整形轮廓参考值和时间间隔值。参考值表示为设备在治疗时间结束时应达到的总重量损失的分数，例如百分比。每个时间间隔值被表示为总治疗时间的分数，或者作为前置实际时间间隔。控制系统基于期望的总重量损失，在期望的总治疗时间以及所选择的所需整形轮廓上计算实际的体重减轻率与时间曲线。

10. 发明申请

WO2005036575A2 MICRO-ELECTROMECHANICAL SWITCHING BACKPLANE 审中-公开
标题翻译：微电子开关背板
公开(公告)号：WO2005036575A2
公开(公告)日：2005-04-21
申请号：PCT/US2004033281
申请日：2004-10-06
申请人： ROLLTRONICS CORP , SAUVANTE MICHAEL D , PASCH NICHOLAS F , SANDERS GLENN C
发明人： SAUVANTE MICHAEL D , PASCH NICHOLAS F , SANDERS GLENN C
IPC分类号： G09G3/34 , G09G3/36 , H01H20060101 , H01H
CPC分类号： H01H59/0009 , G02F2001/1676 , G09G3/20 , G09G2300/08 , H01H9/161 , H01L27/3241
摘要： A low cost, scalable backplane for black and white or color optical displays comprises a multi-membrane plastic structure on which is printed or deposited row and column drivers to form a matrix of micro electromechanical (MEM) switches. Each switch controls the state of a pixel in the optical display device. Critical to successful long-term operation, the backplane includes the controlled application of voltages to each switch so that the display functions correctly and display life is maximized. The MEM switches include a substantially non-pliable membrane and a substantially flexible membrane both of which include electrodes that when energized will create electrostatic forces that attracts the flexible membrane to the non-pliable membrane. The MEM switches are manufactured in an array with a pitch that provides a sufficient number of switches to drive an optical display device and each switch may be latched to eliminate the need to constantly refresh the device.
摘要翻译：用于黑白或彩色光学显示器的低成本，可扩展背板包括多膜塑料结构，印刷或沉积行和列驱动器以形成微机电（MEM）开关的矩阵。每个开关控制光学显示装置中的像素的状态。对于成功的长期运行至关重要，背板包括对每个开关的电压的受控应用，使显示器正常工作并显示寿命最大化。 MEM开关包括基本上不柔软的膜和基本上柔性的膜，两者都包括电极，其在被通电时将产生吸引柔性膜到非柔性膜的静电力。 MEM开关以阵列形式制造，具有提供足够数量的开关以驱动光学显示装置的间距，并且每个开关可被锁存以消除不断刷新装置的需要。

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