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1. 发明申请

WO2011159825A1 INTRAVASCULAR ARTERIAL TO VENOUS ANASTOMOSIS AND TISSUE WELDING CATHETER 审中-公开
标题翻译：静脉血管造影和组织焊接导管的血管内皮细胞
公开(公告)号：WO2011159825A1
公开(公告)日：2011-12-22
申请号：PCT/US2011/040567
申请日：2011-06-15
申请人： CAYMUS MEDICAL, INC. , BAJA RESEARCH, LLC. , KELLERMAN, Brad, M. , ALDRIDGE, David, Trottingwolf , WROLSTAD, David, K. , RITCHART, Mark, A. , HULL, Jeffrey, E.
发明人： KELLERMAN, Brad, M. , ALDRIDGE, David, Trottingwolf , WROLSTAD, David, K. , RITCHART, Mark, A. , HULL, Jeffrey, E.
IPC分类号： A61B18/08
CPC分类号： A61B18/1492 , A61B17/11 , A61B17/320068 , A61B18/08 , A61B18/082 , A61B18/18 , A61B18/24 , A61B2017/1107 , A61B2017/1139 , A61B2018/00386 , A61B2018/00404 , A61B2018/00422 , A61B2018/00595 , A61B2018/00601 , A61B2018/00619 , A61B2018/00714 , A61B2018/1475
摘要： A device for creating an arteriovenous (AV) fistula comprises an elongate member, a distal member connected to the elongate member and movable relative to the elongate member, and a heating member disposed on at least one of the movable distal member and the elongate member. The distal member comprises structure for capturing tissue to be cut to create the fistula, and the heating member is adapted to cut through the tissue to create the fistula. The elongate member comprises an elongate outer tube. A shaft connects the distal member to the elongate member, and is extendable and retractable to extend and retract the distal member relative to the elongate member.
摘要翻译：用于产生动静脉（AV）瘘的装置包括细长构件，远端构件，其连接到细长构件并且可相对于细长构件移动，以及加热构件，其设置在可移动远侧构件和细长构件中的至少一个上。远侧构件包括用于捕获要切割的组织以产生瘘的结构，并且加热构件适于切穿组织以产生瘘。细长构件包括细长的外管。轴将远端构件连接到细长构件，并且可延伸和缩回以相对于细长构件延伸和缩回远侧构件。

2. 发明申请

WO2007143560A2 EXPANDABLE BRACHYTHERAPY APPARATUS 审中-公开
标题翻译：可扩展的BRACHYTHERAPY设备
公开(公告)号：WO2007143560A2
公开(公告)日：2007-12-13
申请号：PCT/US2007/070236
申请日：2007-06-01
申请人： BIOLUCENT, INC. , CHI SING, Eduardo , GEX, Steven, L. , NGUYEN, Tommy, G. , SUTTON, Doug, S. , RITCHART, Mark, A. , HERMANN, George, D.
发明人： CHI SING, Eduardo , GEX, Steven, L. , NGUYEN, Tommy, G. , SUTTON, Doug, S. , RITCHART, Mark, A. , HERMANN, George, D.
CPC分类号： A61N5/1015 , A61N2005/1018
摘要： Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
摘要翻译：用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入组织道并携带多个细长构件，包括用于接收辐射源的路径。细长构件可在折叠和膨胀构型之间移动。在使用期间，通过组织产生管道，并且携带细长构件的细长主体通过管道前进到目标位置，细长构件处于收缩构型。细长构件在目标位置处被引导到扩张构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。

3. 发明申请

WO2007059397A1 HELICAL BRACHYTHERAPY APPARATUS AND METHODS OF USING SAME 审中-公开
标题翻译：螺旋拉伸装置及其使用方法
公开(公告)号：WO2007059397A1
公开(公告)日：2007-05-24
申请号：PCT/US2006/060688
申请日：2006-11-08
申请人： BIOLUCENT, INC. , HERMANN, George, D. , LEBOVIC, Gail, S. , RITCHART, Mark, A.
发明人： HERMANN, George, D. , LEBOVIC, Gail, S. , RITCHART, Mark, A.
IPC分类号： A61N5/10 , A61M36/04
CPC分类号： A61N5/1015 , A61N5/1027 , A61N2005/1018
摘要： Apparatus, systems, and methods are provided for delivering brachytherapy into a target tissue region, e.g., a breast. In some embodiments, a flexible brachytherapy device is implanted that includes a therapy delivery portion having one or more radioactive sources securely retained thereto, and a tail portion extending from the therapy delivery portion. The brachytherapy device may be implanted in a helical configuration within the target tissue region. To assist in placement and removal of the brachytherapy device, a tubular sheath may be implanted by attaching (e.g., sliding over) a helically coiled needle that is advanced into the body by screw-like rotation. Once implanted, the sheath and the brachytherapy device may extend outside the body, where they may be folded and secured flat against the skin. The device and sheath may be removed at therapy completion.
摘要翻译：提供装置，系统和方法用于将近距离放射治疗递送到目标组织区域，例如乳房。在一些实施例中，植入柔性近距离放射治疗装置，其包括具有一个或多个可靠地保持在其上的放射源的治疗递送部分和从治疗递送部分延伸的尾部。近程放射治疗装置可以以目标组织区域内的螺旋形构造植入。为了帮助放置和去除近距离放射治疗装置，可以通过螺旋状旋转将附着（例如，滑过）螺旋卷绕的针头注入身体来植入管状护套。一旦植入，护套和近距离放射治疗装置可以延伸到身体外部，在那里它们可以被折叠并且平坦地固定在皮肤上。在治疗完成时可以移除装置和护套。

4. 发明申请

WO2007056714A1 BRACHYTHERAPY APPARATUS AND METHODS FOR USING THEM 审中-公开
标题翻译： BRACHYTHERAPY设备及其使用方法
公开(公告)号：WO2007056714A1
公开(公告)日：2007-05-18
申请号：PCT/US2006/060581
申请日：2006-11-06
申请人： BIOLUCENT, INC. , HERMANN, George, D. , CHI SING, Eduardo , LEBOVIC, Gail, S. , COLE, Mark, A. , RITCHART, Mark, A. , NGUYEN, Than
发明人： HERMANN, George, D. , CHI SING, Eduardo , LEBOVIC, Gail, S. , COLE, Mark, A. , RITCHART, Mark, A. , NGUYEN, Than
IPC分类号： A61N5/10 , A61M36/00
CPC分类号： A61N5/1015 , A61N2005/1018
摘要： Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members arc directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
摘要翻译：用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。细长构件可在折叠和膨胀构型之间移动。在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。细长构件在目标位置处被引导到扩张构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。

5. 发明申请

WO2011159802A1 SYSTEMS AND METHODS FOR CREATING ARTERIOVENOUS (AV) FISTULAS 审中-公开
标题翻译：用于创建异常（AV）FISTULAS的系统和方法
公开(公告)号：WO2011159802A1
公开(公告)日：2011-12-22
申请号：PCT/US2011/040530
申请日：2011-06-15
申请人： CAYMUS MEDICAL, INC. , BAJA RESEARCH, LLC. , HULL, Jeffrey, E. , RITCHART, Mark, A. , WROLSTAD, David
发明人： HULL, Jeffrey, E. , RITCHART, Mark, A. , WROLSTAD, David
IPC分类号： A61B17/08
CPC分类号： A61M1/3655 , A61B17/11 , A61B17/320068 , A61B17/34 , A61B18/082 , A61B18/1492 , A61B18/18 , A61B2017/1107 , A61B2017/1139 , A61B2018/00386 , A61B2018/00577 , A61B2018/00601 , A61B2018/00619 , A61B2018/00714 , A61B2018/00922 , A61B2018/1425 , A61B2018/1475 , A61M25/09041 , A61N7/02
摘要： A system for creating an arteriovenous (AV) fistula comprises a vessel access sheath having a hollow interior and an exit port, a side access needle catheter configured to fit within the hollow interior of the sheath, a needle configured to be inserted into a blood vessel through the side access needle catheter, a toggle delivery catheter configured to fit within the hollow interior of the sheath, and a toggle apparatus configured to be delivered into a vessel through the toggle delivery catheter. The toggle apparatus comprises a shaft and a toggle member pivotably attached to a distal end of the shaft. A source of RF energy or resistive heat energy may be provided for application to the toggle member and/or to a heater insert in the toggle delivery catheter, for the purpose of creating the fistula.
摘要翻译：用于产生动静脉（AV）瘘的系统包括具有中空内部和出口的容器进入护套，配置成装配在护套的中空内部的侧进针针导管，构造成插入血管通过侧进针针导管，配置成装配在护套的中空内部的肘节递送导管，以及构造成通过肘节递送导管输送到血管中的肘节装置。肘节装置包括轴和可枢转地附接到轴的远端的肘节构件。为了产生瘘，可以提供RF能量或电阻热能源用于施加到肘节构件和/或肘节递送导管中的加热器插入件。

6. 发明申请

WO2007143560A3 EXPANDABLE BRACHYTHERAPY APPARATUS 审中-公开
标题翻译：可扩展的BRACHYTHERAPY设备
公开(公告)号：WO2007143560A3
公开(公告)日：2008-05-02
申请号：PCT/US2007070236
申请日：2007-06-01
申请人： BIOLUCENT INC , CHI SING EDUARDO , GEX STEVEN L , NGUYEN TOMMY G , SUTTON DOUG S , RITCHART MARK A , HERMANN GEORGE D
发明人： CHI SING EDUARDO , GEX STEVEN L , NGUYEN TOMMY G , SUTTON DOUG S , RITCHART MARK A , HERMANN GEORGE D
IPC分类号： A61N5/10
CPC分类号： A61N5/1015 , A61N2005/1018
摘要： Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
摘要翻译：用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。细长构件可在折叠和膨胀构型之间移动。在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。细长构件在目标位置处被引导到扩展构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。

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