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1. 发明申请

WO2013030535A3 METHOD OF PREPARING CARRIER LIQUIDS 审中-公开
公开(公告)号：WO2013030535A3
公开(公告)日：2013-03-07
申请号：PCT/GB2012/052028
申请日：2012-08-20
申请人： IOTA NANOSOLUTIONS LIMITED , FOSTER, Alison Jayne , LONG, James , RANNARD, Steven Paul , WANG, Dong
发明人： FOSTER, Alison Jayne , LONG, James , RANNARD, Steven Paul , WANG, Dong
IPC分类号： A01N25/04 , A61K8/04 , A61K9/107 , A61K47/30 , A61Q19/00 , B82Y5/00
摘要： The invention provides a method for the preparation of a carrier liquid which comprises the steps of: (I) preparing a single phase solution comprising: (a) a solvent or a mixture of miscible solvents, (b) a liquid carrier material, which is soluble in solvent (a), and (c) a dopant material which is also soluble in solvent (a); (II) cooling (preferably freezing) the single phase solution produced in step (I) to a temperature at which at least both the solvent (a) and carrier material (b) become solid; and (III) removing solid solvent (a) from the cooled (frozen) single phase solution in vapour form, such that the remaining cooled (frozen) carrier material (b) and dopant material (c) are returned to ambient temperature thus providing a product of liquid carrier material (b) having dopant material (c) dispersed therein.

2. 发明申请

WO2010149962A1 BRANCHED POLYMER DISPERSANTS 审中-公开
标题翻译：分支聚合物分散剂
公开(公告)号：WO2010149962A1
公开(公告)日：2010-12-29
申请号：PCT/GB2010/001224
申请日：2010-06-22
申请人： UNILEVER PLC , FINDLAY, Paul, Hugh , ROYLES, Brodyck, James, Lachlan , BAUDRY, Roselyne, Marie, Andree , SIMPSON, Neil, John , TODD, Sharon , RANNARD, Steven, Paul
发明人： FINDLAY, Paul, Hugh , ROYLES, Brodyck, James, Lachlan , BAUDRY, Roselyne, Marie, Andree , SIMPSON, Neil, John , TODD, Sharon , RANNARD, Steven, Paul
IPC分类号： B01F17/42 , C08F2/38 , C08F212/08 , C09D17/00 , C08F220/06 , C08F220/34 , C08F226/06 , B01F17/00
CPC分类号： C08F2/38 , B01F17/0028 , B01F17/005 , C04B24/2641 , C04B24/2652 , C04B2103/408 , C08F220/06 , C08F220/28 , C08F220/34 , C08F222/1006 , C08F226/06 , C09D5/033 , C09D7/45 , C09D17/00 , C08F212/08 , C08F2222/1013 , C08F220/56
摘要： The present invention relates to the use of a branched addition copolymer as a dispersant in a gaseous, liquid or solid formulation in a range of applications and branched addition copolymers suitable for same wherein the copolymer is obtainable by an addition polymerisation process, wherein said copolymer comprises: at least two chains which are covalently linked by a bridge other than at their ends; and wherein the at least two chains comprise at least one ethyleneically monounsaturated monomer, and wherein the bridge comprises at least one ethyleneically polyunsaturated monomer; and wherein the polymer comprises a residue of a chain transfer agent and wherein the mole ratio of polyunsaturated monomer(s) to monounsaturated monomer(s) is in a range of from 1:100 to 1:4; and wherein the branched copolymer dispersant contains anchoring, solubilising or stabilising moieties and wherein the resulting copolymer comprises at least 10% styrenic monomer, brancher or chain transfer agent.
摘要翻译：本发明涉及在一系列应用中的支化加成共聚物作为分散剂在分散剂中的应用和适用于其的支化加成共聚物的用途，其中共聚物可通过加成聚合方法获得，其中所述共聚物包含：至少两条由桥以外的其他端部共价连接的链; 并且其中所述至少两个链包含至少一个亚乙基单不饱和单体，并且其中所述桥包含至少一个亚乙基多不饱和单体; 并且其中所述聚合物包含链转移剂的残基，并且其中多不饱和单体与单不饱和单体的摩尔比在1:100至1:4的范围内; 并且其中所述支化共聚物分散剂含有锚定，增溶或稳定部分，并且其中所得共聚物包含至少10％苯乙烯单体，分枝剂或链转移剂。

3. 发明申请

WO2010149957A1 BRANCHED POLYMER DISPERSANTS 审中-公开
标题翻译：分支聚合物分散剂
公开(公告)号：WO2010149957A1
公开(公告)日：2010-12-29
申请号：PCT/GB2010/001214
申请日：2010-06-22
申请人： UNILEVER PLC , FINDLAY, Paul, Hugh , ROYLES, Brodyck, James, Lachlan , BAUDRY, Roselyne, Marie, Andree , SIMPSON, Neil, John , TODD, Sharon , RANNARD, Steven, Paul
发明人： FINDLAY, Paul, Hugh , ROYLES, Brodyck, James, Lachlan , BAUDRY, Roselyne, Marie, Andree , SIMPSON, Neil, John , TODD, Sharon , RANNARD, Steven, Paul
IPC分类号： B01F17/42 , C08F2/38 , C08F212/08 , C09D17/00 , C08F220/06 , C08F220/34 , C08F226/06
CPC分类号： C08F2/38 , B01F17/0057 , C08F212/08 , C08F212/36 , C08F220/06 , C08F220/34 , C08F222/1006 , C08F226/06 , C09D5/033 , C09D7/45 , C09D17/00
摘要： The present invention relates to the use of a branched addition copolymer as a dispersant in a gaseous, liquid or solid formulation in a range of applications and to the copolymers per se wherein the copolymer is obtainable by an addition polymerisation process, wherein said copolymer comprises: at least two chains which are covalently linked by a bridge other than at their ends; and wherein the at least two chains comprise at least one ethyleneically monounsaturated monomer, and wherein the bridge comprises at least one ethyleneically polyunsaturated monomer; and wherein the polymer comprises a residue of a chain transfer agent and wherein the mole ratio of polyunsaturated monomer(s) to monounsaturated monomer(s) is in a range of from 1 :100 to 1 :4; and wherein the branched copolymer dispersant contains anchoring, solubilising or stabilising moieties and wherein the resulting copolymer has a weight average molecular weight of less than 100,000 Da.
摘要翻译：本发明涉及一种支链加成共聚物作为分散剂在一系列应用中的用途和共聚物本身的气态，液体或固体制剂的用途，其中共聚物可通过加成聚合方法获得，其中所述共聚物包含：至少两条链，其不是在其端部以外的桥共价连接; 并且其中所述至少两个链包含至少一个亚乙基单不饱和单体，并且其中所述桥包含至少一个亚乙基多不饱和单体; 并且其中所述聚合物包含链转移剂的残基，并且其中多不饱和单体与单不饱和单体的摩尔比在1:100至1:4的范围内; 并且其中所述支化共聚物分散剂含有锚定，增溶或稳定部分，并且其中所得共聚物的重均分子量小于100,000Da。

4. 发明申请

WO2010089571A1 BRANCHED COPOLYMERS, COMPOSITIONS AND USES 审中-公开
标题翻译：分支共聚物，组合物和用途
公开(公告)号：WO2010089571A1
公开(公告)日：2010-08-12
申请号：PCT/GB2010/000227
申请日：2010-02-09
申请人： UNILEVER PLC , FINDLAY, Paul, Hugh , ROYLES, Brodyck, James, Lachlan , SIMPSON, Neil, John , TODD, Sharon , RANNARD, Steven, Paul , WEAVER, Jonathan, Victor, Mark , BAUDRY, Roselyne, Marie, Andree
发明人： FINDLAY, Paul, Hugh , ROYLES, Brodyck, James, Lachlan , SIMPSON, Neil, John , TODD, Sharon , RANNARD, Steven, Paul , WEAVER, Jonathan, Victor, Mark , BAUDRY, Roselyne, Marie, Andree
IPC分类号： C08F2/38 , C08F2/42 , C08F212/08 , C08F220/06 , C08F220/16 , C08F220/26 , C08F220/34
CPC分类号： C08F2/38 , C08F212/08 , C08F212/36 , C08F220/18 , C08F222/1006 , C08F2220/1825 , C08F220/20 , C08F220/06 , C08F2222/1013 , C08F226/10
摘要： The present invention relates to a branched copolymer obtainable by an addition polymerisation process and uses and compositions thereof comprising: i) a residue of at least one monofunctional monomer comprising one polymerisable double bond per molecule and a molecular weight of less than 1000 Daltons; ii) a residue of at least one multifunctional monomer comprising at least two polymerisable double bonds per molecule and a molecular weight of less than 1000 Daltons; and wherein the end termini of the copolymer chains comprise one or more of a residue of a chain transfer agent; an initiator or a terminal group derived from a termination reaction; wherein; the molar ratio of the monofunctional monomer to multifunctional monomer is between 50 :1 to 2.5 :1 respectively; and wherein the hydrophilic component is comprised of at least 1 mole % of a combination of a monofunctional monomer, and a multifunctional monomer and/or a chain transfer agent when compared to the total content of monofunctional monomer which is/are comprised of hydrophilic component each with a solubility of 0.18 w/w % in water at 2O0C; and wherein the residue of the at least one monofunctional monomer with a molecular weight of less than 1000 daltons is selected from the group comprising: vinyl acids, vinyl acid ester, vinyl aryl compounds, vinyl acid anhydrides, vinyl amides, vinyl ethers, vinyl amines, vinyl aryl amines, vinyl nitriles, vinyl ketones, and derivatives thereof; hydroxyl-containing monomers and monomers which can be post-reacted to form hydroxyl groups; acid-containing or acid functional monomers; zwitterionic monomers; quaternised amino monomers, oligomeric monomers; and corresponding allyl monomers of the aforesaid vinyl monomers.
摘要翻译：本发明涉及可通过加成聚合方法获得的支链共聚物及其用途及其组合物，其包含：i）至少一种单分子的残基，其每分子包含一个可聚合双键，分子量小于1000道尔顿; ii）至少一种多官能单体的残基，每个分子包含至少两个可聚合双键，分子量小于1000道尔顿; 并且其中共聚物链的末端包含一个或多个链转移剂的残基; 来自终止反应的引发剂或末端基团; 其中; 单官能单体与多官能单体的摩尔比分别为50:1至2.5:1; 并且其中亲水性组分由至少1摩尔％的单官能单体和多官能单体和/或链转移剂的组合组成，当与由各亲水组分组成的单官能单体的总含量相比时溶解度为0.18w / w％，在水中20℃; 并且其中所述至少一种分子量小于1000道尔顿的单官能单体的残基选自：乙烯基酸，乙烯基酸酯，乙烯基芳基化合物，乙烯基酸酐，乙烯基酰胺，乙烯基醚，乙烯基胺乙烯基芳基胺，乙烯基腈，乙烯基酮及其衍生物; 含羟基的单体和可以后反应形成羟基的单体; 含酸或酸官能单体; 两性离子单体; 季铵化氨基单体，低聚单体; 和上述乙烯基单体的相应的烯丙基单体。

5. 发明申请

WO2008006712A3 PREPARATION OF NANODISPERSIONS 审中-公开
标题翻译：纳米尺度的制备
公开(公告)号：WO2008006712A3
公开(公告)日：2009-02-26
申请号：PCT/EP2007056560
申请日：2007-06-29
申请人： UNILEVER PLC , UNILEVER NV , ANGUS DORIS , DUNCALF DAVID JOHN , ELPHICK ANDREW JAMES , FOSTER ALISON JAYNE , LONG JAMES , RANNARD STEVEN PAUL , WANG DONG
发明人： ANGUS DORIS , DUNCALF DAVID JOHN , ELPHICK ANDREW JAMES , FOSTER ALISON JAYNE , LONG JAMES , RANNARD STEVEN PAUL , WANG DONG
IPC分类号： A61K9/16 , A01N31/16 , A01N37/50 , A01N43/653 , A01N53/00 , A23L27/00
CPC分类号： A61K9/1617 , A01N25/04 , A61K9/10 , A61K9/1635 , A61K9/1641 , A61K9/1652 , A61K9/19 , A61K31/167 , A01N43/54 , A01N53/00 , A01N31/16 , A01N37/18
摘要： The invention provides process for making contra-soluble nano-dispersions of at most sparingly-soluble materials in a soluble carrier material comprising the steps of: (i) providing a single phase mixture of: a) a solvent or a mixture of miscible solvents, b) at least one carrier material soluble in solvent (a), said carrier material being also contra-soluble to payload material (c) and solid at ambient temperature, c) at least one a payload material which is soluble in solvent (a), and, (ii) drying the mixture to remove solvent (a) and thereby obtain the carrier material (b) in solid form with payload (c) dispersed therein as nanoparticles.
摘要翻译：本发明提供了在可溶性载体材料中制备至多微溶性材料的可溶性纳米分散体的方法，其包括以下步骤：（i）提供单相混合物：a）溶剂或可混溶溶剂的混合物， b）可溶于溶剂（a）的至少一种载体材料，所述载体材料在环境温度下也可溶于有效载荷材料（c）和固体，c）至少一种可溶于溶剂（a）的有效载荷材料，，和（ii）干燥混合物以除去溶剂（a），从而获得固体形式的载体材料（b），其中有效载荷（c）作为纳米颗粒分散在其中。

6. 发明申请

WO2005075546A1 POROUS BODIES AND METHOD OF PRODUCTION THEREOF 审中-公开
标题翻译：多孔体及其生产方法
公开(公告)号：WO2005075546A1
公开(公告)日：2005-08-18
申请号：PCT/EP2004/014755
申请日：2004-12-23
申请人： UNILEVER PLC , UNILEVER NV , HINDUSTAN LEVER LIMITED , COOPER, Andrew, Ian , FOSTER, Alison, Jayne , RANNARD, Steven, Paul , ZHANG, Haifei
发明人： COOPER, Andrew, Ian , FOSTER, Alison, Jayne , RANNARD, Steven, Paul , ZHANG, Haifei
IPC分类号： C08J9/16
CPC分类号： C11D17/0034
摘要： Porous bodies which are soluble or dispersible in non-aqueous media comprising a three dimensional open-cell lattice containing (a) 10 to 70% by weight of a polymeric material which is soluble in water immiscible non-aqueous media and (b) 30 to 90% by weight of a surfactant, said porous bodies having an intrusion volume as measured by mercury porosimetry of at least 3 ml/g.
摘要翻译：在非水介质中可溶或可分散的多孔体，其包含三维开孔格子，其含有（a）10至70重量％的可溶于水不混溶的非水介质的聚合物材料，和（b）30至 90重量％的表面活性剂，所述多孔体具有至少3ml / g的通过水银孔率法测定的侵入体积。

7. 发明申请

WO2005027862A1 ORAL COMPOSITION COMPRISING A COPOLYMER COMPRISING CATIONIC AND ANIONIC OR NEUTRAL COMONOMERS 审中-公开
标题翻译：包含阳离子和中性成分的共聚物的口服组合物
公开(公告)号：WO2005027862A1
公开(公告)日：2005-03-31
申请号：PCT/EP2004/009267
申请日：2004-08-18
申请人： UNILEVER N.V. , UNILEVER PLC , HINDUSTAN LEVER LIMITED , CHARMOT, Dominique , GIBBS, Christopher, David , KOLOSOV, Oleg , LIU, Mingjun , NGUYEN, Son, Hoai , PETRO, Miroslav , RANNARD, Steven, Paul , NAVA-SALGADO, Victor , CHANG, Han, Ting , DUNCALF, David
发明人： CHARMOT, Dominique , GIBBS, Christopher, David , KOLOSOV, Oleg , LIU, Mingjun , NGUYEN, Son, Hoai , PETRO, Miroslav , RANNARD, Steven, Paul , NAVA-SALGADO, Victor , CHANG, Han, Ting , DUNCALF, David
IPC分类号： A61K7/16
CPC分类号： A61K8/86 , A61K8/8158 , A61K2800/5426 , A61Q11/00
摘要： Oral care composition comprising a polymer obtainable by copolymerising a mixture of comonomers, said mixture comprising: (a) a cationic monomer selected from (ar-vinylbenzyl) trimethylammonium chloride, (dimethylaminopropyl) methacrylamide, [2(methacryloyloxy)ethyl]trimethylammonium chloride, 2-aminoethylmethacrylate hydrochloride and mixtures thereof; and (b) at least one anionic or neutral monomer selected from styrene, mono-2-(methacryloyl)ethyl succinate, vinyl acetate, N,N-dimethylacrylamide, 2-ethylhexylacrylate, vinylphosphonic acid, acrylic acid, 2-acrylamido-2-methyl-1-propanesulfonic acid, N-[tris(hydroxymethyl)methyl] acrylamide, N-vinylpyrrolidone, butyl acrylate, 2-hydroxyethylacrylate, polyethyleneglycol methylethermethacrylate and mixtures thereof, said oral care composition in the form of any one of a toothpaste, gel, foam, chewing gum, deformable strip or mouthwash and which is suitable for use in the oral cavity.
摘要翻译：所述混合物包含：（a）阳离子单体，选自（芳基乙烯基苄基）三甲基氯化铵，（二甲基氨基丙基）甲基丙烯酰胺，[2（甲基丙烯酰氧基）乙基]三甲基氯化铵，2 甲基丙烯酸氨基乙酯盐酸盐及其混合物; 和（b）至少一种阴离子或中性单体，其选自苯乙烯，琥珀酸单-2-（甲基丙烯酰）乙酯，乙酸乙烯酯，N，N-二甲基丙烯酰胺，丙烯酸2-乙基己酯，乙烯基膦酸，丙烯酸，2-丙烯酰胺基-2- 甲基-1-丙磺酸，N- [三（羟甲基）甲基]丙烯酰胺，N-乙烯基吡咯烷酮，丙烯酸丁酯，丙烯酸2-羟乙酯，聚乙二醇甲基醚甲基丙烯酸酯及其混合物，所述口腔护理组合物为牙膏，凝胶，泡沫，口香糖，可变形条或漱口水，适用于口腔。

8. 发明申请

WO2012143733A1 NANOPARTICLES 审中-公开
标题翻译：纳米粒子
公开(公告)号：WO2012143733A1
公开(公告)日：2012-10-26
申请号：PCT/GB2012/050884
申请日：2012-04-20
申请人： THE UNIVERSITY OF LIVERPOOL , GIARDIELLO, Marco, Norman , MCDONALD, Thomas, Oliver , OWEN, Andrew , RANNARD, Steven, Paul
发明人： GIARDIELLO, Marco, Norman , MCDONALD, Thomas, Oliver , OWEN, Andrew , RANNARD, Steven, Paul
IPC分类号： H01F1/00 , C08J9/28
CPC分类号： C08J9/283 , A61K9/19 , A61K9/5192 , B82Y25/00 , C08J3/12 , C08J3/20 , C08J2201/048 , H01F1/0054
摘要： The present invention relates to a porous composite material comprising a hydrophilic carrier carrying a magnetic material. The porous composite material can include a hydrophobic polymer, hydrophobic material, organic compound, and/or pharmaceutically active ingredient. The porous composite material is prepared by a modified emulsion templating and freeze-drying procedure. Magnetic nanoparticles are released from the porous composite material on application of water.
摘要翻译：本发明涉及一种包含承载磁性材料的亲水载体的多孔复合材料。多孔复合材料可以包括疏水性聚合物，疏水性材料，有机化合物和/或药物活性成分。多孔复合材料通过改性乳液模板和冷冻干燥方法制备。在应用水时，磁性纳米颗粒从多孔复合材料中释放出来。

9. 发明申请

WO2011128623A3 IMPROVEMENTS RELATING TO ANTIVIRAL COMPOSITIONS 审中-公开
标题翻译：有关组合物的改进
公开(公告)号：WO2011128623A3
公开(公告)日：2012-05-03
申请号：PCT/GB2011000549
申请日：2011-04-08
申请人： IOTA NANOSOLUTIONS LTD , FOSTER ALISON JAYNE , LONG JAMES , RANNARD STEVEN PAUL , WANG DONG , DUNCALF DAVID JOHN
发明人： FOSTER ALISON JAYNE , LONG JAMES , RANNARD STEVEN PAUL , WANG DONG , DUNCALF DAVID JOHN
IPC分类号： A61K9/51
CPC分类号： A61K9/10 , A61K9/5123 , A61K9/5138 , A61K9/5146 , A61K9/5161 , A61K9/5192 , A61K31/427 , A61K31/4725 , A61K31/513 , A61K31/536 , A61K47/10 , A61K47/32 , A61K47/38
摘要： The present invention provides a composition and an antiviral drug preparation, each comprising at least one water-insoluble antiviral drug and at least one water-soluble carrier material, wherein the water-insoluble antiviral drug is dispersed through the water-soluble carrier material in nano-disperse form. The present invention further provides processes for preparing the compositions and drug preparations, and also aqueous nano-dispersions obtained by combining water and the compositions.
摘要翻译：本发明提供一种组合物和抗病毒药物制剂，每种组合物和抗病毒药物制剂各自包含至少一种水不溶性抗病毒药物和至少一种水溶性载体材料，其中所述水不溶性抗病毒药物通过纳米级的水溶性载体材料分散 - 分散形式。本发明还提供了制备组合物和药物制剂的方法，以及通过将水和组合物组合获得的水性纳米分散体。

10. 发明申请

WO2011033262A1 USE OF BRANCHED ADDITION COPOLYMERS IN CURING SYSTEMS 审中-公开
标题翻译：分支添加共聚物在固化体系中的应用
公开(公告)号：WO2011033262A1
公开(公告)日：2011-03-24
申请号：PCT/GB2010/001741
申请日：2010-09-16
申请人： UNILEVER PLC , FINDLAY, Paul Hugh , TODD, Sharon , RANNARD, Steven Paul , ROYLES, Brodychk James Lachlan , SIMPSON, Neil John , BAUDRY, Roselyne Marie Andree
发明人： FINDLAY, Paul Hugh , TODD, Sharon , RANNARD, Steven Paul , ROYLES, Brodychk James Lachlan , SIMPSON, Neil John , BAUDRY, Roselyne Marie Andree
IPC分类号： C08F2/38 , C08F212/08 , C08F212/36 , C08F220/28 , C08F220/32 , C08F222/10 , C09D133/06 , C09D133/14 , C09D135/06 , C09J133/06 , C09J133/14 , C09J135/06
CPC分类号： C08F220/14 , C08F2/38 , C08F212/36 , C08G18/6229 , C08G18/6254 , C09D133/066 , C09D133/12 , C09J133/12 , C08F2220/1825 , C08F222/1006 , C08F222/26 , C08F2220/281
摘要： The present invention relates to the use of branched addition copolymers in systems which can be cured post synthesis to form for example polymer coatings, sealants, inks, adhesives or composites and also relates to methods of preparing the cured systems, compositions comprising such copolymers and the use of the compositions in for example but not limited to coatings, inks, sealants, adhesives or composites.
摘要翻译：本发明涉及分支加成共聚物在可以在后合成固化以形成例如聚合物涂料，密封剂，油墨，粘合剂或复合材料的体系中的用途，还涉及制备固化体系的方法，包含这种共聚物的组合物和组合物在例如但不限于涂料，油墨，密封剂，粘合剂或复合材料中的使用。

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