专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2003027112A1 1, 8-NAPHTHYRIDINE DERIVATIVES AS ANTIDIABETICS 审中-公开
标题翻译： 1，8-萘啶衍生物作为抗生素
公开(公告)号：WO2003027112A1
公开(公告)日：2003-04-03
申请号：PCT/US2002/030176
申请日：2002-09-23
申请人： BAYER CORPORATION , WANG, Yamin , GUNN, David, E. , LIU, Qingjie , LIANG, Sidney, X. , BULLOCK, William, H. , LIU, Donglei , MAGNUSON, Steven, R. , LI, Tindy , MULL, Eric, S. , WOOD, Jill, E. , QI, Ning
发明人： WANG, Yamin , GUNN, David, E. , LIU, Qingjie , LIANG, Sidney, X. , BULLOCK, William, H. , LIU, Donglei , MAGNUSON, Steven, R. , LI, Tindy , MULL, Eric, S. , WOOD, Jill, E. , QI, Ning
IPC分类号： C07D471/04
CPC分类号： A61K45/06 , A61K31/44 , A61K31/496 , A61K31/5377 , A61K31/541 , C07D471/04 , A61K2300/00
摘要： The invention relates generally to naphthyridine derivatives of the formula wherein one of U, X, Y and Z is nitrogen and the others are C-R, where R is hydrogen or a substituent. More specifically, the invention relates to 1,8-naphthyridine derivatives and pharmaceutical compositions containing such derivatives. Methods of the invention comprise administration of a naphthyridine derivative of the invention for the treatment of diabetes and related disorders.
摘要翻译：本发明一般涉及下式的萘啶衍生物，其中U，X，Y和Z中的一个为氮，其余为C-R，其中R为氢或取代基。更具体地，本发明涉及1,8-萘啶衍生物和含有这些衍生物的药物组合物。本发明的方法包括施用本发明的萘啶衍生物用于治疗糖尿病和相关疾病。

2. 发明申请

WO2009042543A1 PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING CANCER THROUGH INHIBITION OF AURORA KINASE 审中-公开
标题翻译：用于通过抑制激素激酶治疗癌症的吡咯烷酮衍生物
公开(公告)号：WO2009042543A1
公开(公告)日：2009-04-02
申请号：PCT/US2008/077211
申请日：2008-09-22
申请人： BAYER HEALTHCARE LLC , MAGNUSON, Steven , WICKENS, Philip , ZHANG, Zhonghua , QI, Ning , MA, Xin
发明人： MAGNUSON, Steven , WICKENS, Philip , ZHANG, Zhonghua , QI, Ning , MA, Xin
IPC分类号： A01N43/64 , A61K31/53
CPC分类号： C07D487/04
摘要： This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly Cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly Cancer.
摘要翻译：本发明涉及新化合物及其制备方法，治疗疾病，特别是癌症的方法，包括给药所述化合物，以及制备用于治疗或预防病症，特别是癌症的药物组合物的方法。

3. 发明申请

WO2005086656A2 HETEROARYLAMINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES 审中-公开
标题翻译：用于治疗糖尿病的异丙基氨基吡唑衍生物
公开(公告)号：WO2005086656A2
公开(公告)日：2005-09-22
申请号：PCT/US2005/005794
申请日：2005-02-24
申请人： BAYER PHARMACEUTICALS CORPORATION , RUDOLPH, Joachim , WICKENS, Philip , CHUANG, Chih-Yuan , CHEN, Libing , MAGNUSON, Steven , OLAGUE, Alan , QI, Ning
发明人： RUDOLPH, Joachim , WICKENS, Philip , CHUANG, Chih-Yuan , CHEN, Libing , MAGNUSON, Steven , OLAGUE, Alan , QI, Ning
IPC分类号： A61K31/4155 , A61K31/4439 , A61K31/506 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/14
CPC分类号： C07D401/12 , C07D403/12 , C07D405/12 , C07D409/14
摘要： The present invention relates to heteroarylaminopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.
摘要翻译：本发明涉及杂芳基氨基吡唑化合物，药物组合物和治疗糖尿病和相关疾病的方法。

4. 发明申请

WO2017106069A1 ANTIVIRAL OXIME PHOSPHORAMIDE COMPOUNDS 审中-公开
标题翻译：抗病毒OXIME PHARMPHARIDIDE化合物
公开(公告)号：WO2017106069A1
公开(公告)日：2017-06-22
申请号：PCT/US2016/066075
申请日：2016-12-12
申请人： MERCK SHARP & DOHME CORP. , FU, Wenlang , GUO, Zhiqiang , QI, Ning , RAHEEM, Izzat, T. , VACHAL, Petr , WANG, Ming , SCHREIER, John, D.
发明人： FU, Wenlang , GUO, Zhiqiang , QI, Ning , RAHEEM, Izzat, T. , VACHAL, Petr , WANG, Ming , SCHREIER, John, D.
IPC分类号： C07F9/24 , A61K31/675 , C07F9/655
CPC分类号： A61K31/675 , C07F9/65616
摘要： Compounds of Formula I: I and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.
摘要翻译：式I化合物：I及其可药用盐可用于抑制HIV逆转录酶。该化合物还可用于预防或治疗HIV感染和预防，延缓AIDS的发作或进展以及治疗。化合物及其盐可以用作药物组合物中的成分，任选地与其他抗病毒剂，免疫调节剂，抗生素或疫苗组合使用。

5. 发明申请

WO2005086656A3 HETEROARYLAMINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES 审中-公开
标题翻译：杂芳基氨基吡唑衍生物用于治疗糖尿病
公开(公告)号：WO2005086656A3
公开(公告)日：2005-12-29
申请号：PCT/US2005005794
申请日：2005-02-24
申请人： BAYER PHARMACEUTICALS CORP , RUDOLPH JOACHIM , WICKENS PHILIP , CHUANG CHIH-YUAN , CHEN LIBING , MAGNUSON STEVEN , OLAGUE ALAN , QI NING
发明人： RUDOLPH JOACHIM , WICKENS PHILIP , CHUANG CHIH-YUAN , CHEN LIBING , MAGNUSON STEVEN , OLAGUE ALAN , QI NING
IPC分类号： A61K31/4155 , A61K31/4439 , A61K31/506 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/14
CPC分类号： C07D401/12 , C07D403/12 , C07D405/12 , C07D409/14
摘要： The present invention relates to heteroarylaminopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.
摘要翻译：本发明涉及杂芳基氨基吡唑化合物，药物组合物和治疗糖尿病和相关疾病的方法。

6. 发明申请

WO2004050651A1 ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES 审中-公开
标题翻译：用于治疗糖尿病的抗炎药衍生物
公开(公告)号：WO2004050651A1
公开(公告)日：2004-06-17
申请号：PCT/US2003/037829
申请日：2003-11-25
申请人： BAYER PHARMACEUTICALS CORPORATION , RUDOLPH, Joachim , CANTIN, Louis-David , MAGNUSON, Steven , BULLOCK, William , BULLION, Ann-Marie , CHEN, Libing , CHUANG, Chih-Yuan , LIANG, Sidney , MAJUMDAR, Dyuti , OGUTU, Herbert , OLAGUE, Alan , QI, Ning , WICKENS, Philip, L.
发明人： RUDOLPH, Joachim , CANTIN, Louis-David , MAGNUSON, Steven , BULLOCK, William , BULLION, Ann-Marie , CHEN, Libing , CHUANG, Chih-Yuan , LIANG, Sidney , MAJUMDAR, Dyuti , OGUTU, Herbert , OLAGUE, Alan , QI, Ning , WICKENS, Philip, L.
IPC分类号： C07D401/04
CPC分类号： C07D231/38 , C07D401/04 , C07D403/12 , C07D413/12 , C07D471/04
摘要： The present invention relates to anilinopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.
摘要翻译：本发明涉及苯胺基吡唑化合物，药物组合物和治疗糖尿病及相关疾病的方法。

7. 发明申请

WO2011084345A1 A METHOD FOR RAPIDLY EVALUATING PERFORMANCE OF SHORT INTERFERING RNA WITH NOVEL CHEMICAL MODIFICATIONS 审中-公开
标题翻译：快速评估短暂干扰RNA与新化学物质修饰性能的方法
公开(公告)号：WO2011084345A1
公开(公告)日：2011-07-14
申请号：PCT/US2010/059696
申请日：2010-12-09
申请人： MERCK SHARP & DOHME CORP. , BUTORA, Gabor , DAVIES, Ian, W. , FLANAGAN, William Michael , FU, Wenlang , KENSKI, Denise, M. , QI, Ning
发明人： BUTORA, Gabor , DAVIES, Ian, W. , FLANAGAN, William Michael , FU, Wenlang , KENSKI, Denise, M. , QI, Ning
IPC分类号： C12Q1/68 , C40B30/10
CPC分类号： C12N15/113 , C12N15/111 , C12N2310/14 , C12N2310/32 , C12N2310/322 , C12N2310/331 , C12N2320/11 , C12N2320/51
摘要： It is an object of the instant invention to provide a method for the rapid evaluation of novel sugar modifications to be used in siRNA synthesis including the rapid evaluation of chemical modification patterns within the siRNA to effectuate increased stability and ultimately increased efficacy of a siRNA therapeutic. It is a further object of the instant invention to provide novel nucleosides useful for siRNA therapy.
摘要翻译：本发明的一个目的是提供一种用于快速评估用于siRNA合成中的新型糖修饰的方法，包括快速评估siRNA内的化学修饰模式以实现增加的稳定性并最终提高siRNA治疗剂的功效。本发明的另一个目的是提供可用于siRNA治疗的新型核苷。

8. 发明申请

WO2010016828A1 METHOD AND APPARATUS FOR REDUCING DEPOSITS IN PETROLEUM PIPES 审中-公开
标题翻译：减少石油管道沉积物的方法和装置
公开(公告)号：WO2010016828A1
公开(公告)日：2010-02-11
申请号：PCT/US2008/072137
申请日：2008-08-04
申请人： MAI, Qi, Ning
发明人： MAI, Qi, Ning
IPC分类号： E21B37/06 , F16L55/24
CPC分类号： F16L55/24 , B08B9/027
摘要： An embodiment of an apparatus for removing deposits from a petroleum flow line may include a pipe capable of being attached to a petroleum flow line. The pipe may have a pipe axis that defines a direction for fluid flow in the petroleum flow line. The apparatus may also include a first and a second field winding circumferential Iy disposed around the pipe, and an electric wave generator adapted to electrically communicate an electric wave to the first field winding and the second field winding. In response to the electric wave, the first field winding is adapted to produce a first magnetic field having a first magnetic axis and the second field winding is adapted to produce a second magnetic field having a second magnetic axis. The first magnetic axis may be noncollinear with respect to the second magnetic axis, and at least the first magnetic axis may be noncollinear with respect to the pipe axis.
摘要翻译：用于从石油流动管线去除沉积物的装置的实施例可以包括能够连接到石油流动管线的管道。管道可以具有限定在石油流动管线中流体流动的方向的管轴线。该装置还可以包括设置在管周围的第一和第二场绕组周向Iy和适于将电波电连通到第一场绕组和第二场绕组的电波发生器。响应于电波，第一场绕组适于产生具有第一磁轴的第一磁场，并且第二场绕组适于产生具有第二磁轴的第二磁场。第一磁轴可以相对于第二磁轴是非共线的，并且至少第一磁轴可以相对于管轴线非共线。

9. 发明申请

WO2004050650A1 ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES 审中-公开
标题翻译：苯并噻唑衍生物用于治疗糖尿病
公开(公告)号：WO2004050650A1
公开(公告)日：2004-06-17
申请号：PCT/US2003/037578
申请日：2003-11-21
申请人： BAYER PHARMACEUTICALS CORPORATION , RUDOLPH, Joachim , CANTIN, Louis-David , MAGNUSON, Steven , BULLOCK, William , BULLION, Ann-Marie , CHEN, Libing , CHUANG, Chih-Yuan , LIANG, Sidney , MAJUMDAR, Dyuti , OGUTU, Herbert , OLAGUE, Alan , QI, Ning , WICKENS, Philip, L.
发明人： RUDOLPH, Joachim , CANTIN, Louis-David , MAGNUSON, Steven , BULLOCK, William , BULLION, Ann-Marie , CHEN, Libing , CHUANG, Chih-Yuan , LIANG, Sidney , MAJUMDAR, Dyuti , OGUTU, Herbert , OLAGUE, Alan , QI, Ning , WICKENS, Philip, L.
IPC分类号： C07D401/04
CPC分类号： C07D231/38 , C07D401/04 , C07D403/12 , C07D413/12 , C07D471/04
摘要： The present invention relates to anilinopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.
摘要翻译：本发明涉及苯胺基吡唑化合物，药物组合物以及治疗糖尿病和相关疾病的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式