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1. 发明申请

WO2013169380A1 COIL-TIPPED ANEURYSM DEVICES 审中-公开
标题翻译：线圈式神经元装置
公开(公告)号：WO2013169380A1
公开(公告)日：2013-11-14
申请号：PCT/US2013/031793
申请日：2013-03-14
申请人： PULSAR VASCULAR, INC.
发明人： ABRAMS, Robert, M. , ROUE, Chad , JENSEN, Marc
IPC分类号： A61B17/12 , A61F2/82
CPC分类号： A61B17/12145 , A61B17/12113 , A61B17/12172 , A61F2002/823
摘要： The present disclosure describes implantable therapeutic devices and methods for endovascular placement of devices at a target site, such as an opening at a neck of an aneurysm. In particular, selected embodiments of the present technology comprise a coil loop, or tip, on a portion of the implantable device. The coil tip can provide a soft and/or smooth interface with the aneurysm and can provide improved coverage of the neck of the aneurysm.
摘要翻译：本公开描述了可植入的治疗装置和方法，用于在目标部位例如动脉瘤颈部的开口处的血管内置入装置。具体地，本技术的选定实施例包括在可植入装置的一部分上的线圈环或尖端。线圈尖端可以提供与动脉瘤的柔软和/或平滑的界面，并且可以提供动脉瘤颈部的改善的覆盖。

2. 发明申请

WO2011029063A2 SYSTEMS AND METHODS FOR ENCLOSING AN ANATOMICAL OPENING 审中-公开
标题翻译：用于封闭解剖学开放的系统和方法
公开(公告)号：WO2011029063A2
公开(公告)日：2011-03-10
申请号：PCT/US2010/047908
申请日：2010-09-03
申请人： PULSAR VASCULAR, INC. , CLARKE, Gilbert , GERBERDING, Brent , ABRAMS, Robert, M. , MOLAEI, Masoud
发明人： CLARKE, Gilbert , GERBERDING, Brent , ABRAMS, Robert, M. , MOLAEI, Masoud
IPC分类号： A61B17/12 , A61F2/90
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12118 , A61B17/1214 , A61B17/12145 , A61B17/12172 , A61B17/1219 , A61B2017/00632 , A61B2017/00867 , A61B2017/12054
摘要： Implantable therapeutic devices and methods for endovascular placement of devices at a target site, such an opening at a neck of an aneurysm, are disclosed. Selected embodiments of the present technology have closures that at least partially occlude the neck of an aneurysm to stabilize embolic or coagulative treatment of the aneurysm. In one embodiment, for example, an aneurysm closure device comprises a closure structure and a supplemental stabilizer. The closure structure can have a curved portion configured to extend along a first vessel, such as a side branch of a bifurcated vessel that extends along a lateral axis. The supplemental stabilizer extends from the closure structure along a longitudinal axis transverse to the lateral axis of the first vessel. The supplemental stabilizer is configured to exert an outward force against a second vessel, such as a parent vessel, that extends transversely to the first vessel.
摘要翻译：公开了用于在靶位置处的装置的血管内放置的可植入治疗装置和方法，例如在动脉瘤颈部的开口。本技术的选定实施例具有至少部分闭塞动脉瘤的颈部以使动脉瘤的栓塞或凝固治疗稳定的闭合。在一个实施例中，例如，动脉瘤闭合装置包括封闭结构和补充稳定器。闭合结构可以具有弯曲部分，其被构造成沿第一容器延伸，例如沿着横向轴线延伸的分叉容器的侧分支。补充稳定器从封闭结构沿着横向于第一容器的横向轴线的纵向轴线延伸。辅助稳定器被配置成向横向于第一容器延伸的第二容器（例如母体容器）施加向外的力。

3. 发明申请

WO2007047851A3 METHODS AND SYSTEMS FOR ENDOVASCULARLY CLIPPING AND REPAIRING LUMEN AND TISSUE DEFECTS 审中-公开
标题翻译：用于血管内切除和修复的组织和组织缺陷的方法和系统
公开(公告)号：WO2007047851A3
公开(公告)日：2009-03-26
申请号：PCT/US2006040907
申请日：2006-10-18
申请人： PULSAR VASCULAR INC , ESKRIDGE JOSEPH , CLARKE GILBERT , PEASE MATTHEW , MAST GREGORY MARTIN , MUSKIVITCH JOHN CONRAD
发明人： ESKRIDGE JOSEPH , CLARKE GILBERT , PEASE MATTHEW , MAST GREGORY MARTIN , MUSKIVITCH JOHN CONRAD
IPC分类号： A61B17/08 , A61M29/00
CPC分类号： A61B17/122 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12172 , A61B90/39 , A61B2017/00867 , A61B2017/1205 , A61B2017/12054 , A61F2/06
摘要： An implantable closure structure is delivered using minimally invasive techniques, and inhibits the migration of liquid and particulate matter from inside a physiological cavity or opening, such as an aneurysm or a septal defect, as well as inhibiting the flow of liquid and particulate matter, such as from an associated blood vessel or chamber, into the physiological cavity or opening. The device has a closure structure that covers the neck or opening of a cavity and has one or more anchoring structures for supporting and retaining the closure structure in place across the cavity or opening.
摘要翻译：使用微创技术递送可植入闭合结构，并且抑制液体和颗粒物质从生理空腔或开口内的移动，例如动脉瘤或间隔缺损，以及抑制液体和颗粒物质的流动，例如从相关的血管或腔室进入生理腔或开口。该装置具有覆盖空腔的颈部或开口的封闭结构，并且具有一个或多个锚固结构，用于将闭合结构支撑并保持在空腔或开口上的适当位置。

4. 发明申请

WO2012167150A1 SYSTEMS AND METHODS FOR ENCLOSING AN ANATOMICAL OPENING, INCLUDING SHOCK ABSORBING ANEURYSM DEVICES 审中-公开
标题翻译：用于封闭解剖学开放的系统和方法，包括震动吸收神经元装置
公开(公告)号：WO2012167150A1
公开(公告)日：2012-12-06
申请号：PCT/US2012/040552
申请日：2012-06-01
申请人： PULSAR VASCULAR, INC. , GERBERDING, Brent
发明人： GERBERDING, Brent
IPC分类号： A61B17/12 , A61F2/82
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12118 , A61B17/12145 , A61B17/12172 , A61F2/86 , A61F2002/823 , A61F2230/0026 , A61F2230/0095
摘要： The present technology relates to systems and methods for enclosing an anatomical opening, including shock absorbing aneurysm devices. In some embodiments, the systems include a closure structure comprising a distal-facing aspect configured to at least partially occlude the aneurysm and a supplemental stabilizer connected to the closure structure. The supplemental stabilizer can be configured to reside in a parent artery and press outward against a luminal wall thereof. The systems can further include a shock absorbing structure coupled to a proximal end portion of the closure structure and to a distal end portion of the supplemental stabilizer. The shock absorbing structure can inhibit movement or dislodgement of the closure structure or the supplemental stabilizer relative to the aneurysm.
摘要翻译：本技术涉及用于封闭解剖开口的系统和方法，包括减震动脉瘤装置。在一些实施例中，所述系统包括闭合结构，所述闭合结构包括构造成至少部分闭塞所述动脉瘤的远侧面方面和连接到所述闭合结构的补充稳定器。辅助稳定器可被配置为驻留在母体动脉中并向外压靠其腔壁。该系统还可以包括耦合到封闭结构的近端部分和补充稳定器的远端部分的减震结构。冲击吸收结构可以抑制闭合结构或补充稳定器相对于动脉瘤的移动或移动。

5. 发明申请

WO2007047851A2 METHODS AND SYSTEMS FOR ENDOVASCULARLY CLIPPING AND REPAIRING LUMEN AND TISSUE DEFECTS 审中-公开
标题翻译：用于血管内切除和修复的组织和组织缺陷的方法和系统
公开(公告)号：WO2007047851A2
公开(公告)日：2007-04-26
申请号：PCT/US2006/040907
申请日：2006-10-18
申请人： PULSAR VASCULAR, INC. , ESKRIDGE, Joseph , CLARKE, Gilbert , PEASE, Matthew , MAST, Gregory Martin , MUSKIVITCH, John Conrad
发明人： ESKRIDGE, Joseph , CLARKE, Gilbert , PEASE, Matthew , MAST, Gregory Martin , MUSKIVITCH, John Conrad
IPC分类号： A61B17/08
CPC分类号： A61B17/122 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12172 , A61B90/39 , A61B2017/00867 , A61B2017/1205 , A61B2017/12054 , A61F2/06
摘要： An implantable closure structure is delivered using minimally invasive techniques, and inhibits the migration of liquid and particulate matter from inside a physiological cavity or opening, such as an aneurysm or a septal defect, as well as inhibiting the flow of liquid and particulate matter, such as from an associated blood vessel or chamber, into the physiological cavity or opening. The device has a closure structure that covers the neck or opening of a cavity and has one or more anchoring structures for supporting and retaining the closure structure in place across the cavity or opening.
摘要翻译：使用微创技术递送可植入闭合结构，并且抑制液体和颗粒物质从生理空腔或开口内的移动，例如动脉瘤或间隔缺损，以及抑制液体和颗粒物质的流动，例如从相关的血管或腔室进入生理腔或开口。该装置具有覆盖空腔的颈部或开口的封闭结构，并且具有一个或多个锚固结构，用于将闭合结构支撑并保持在空腔或开口上的适当位置。

6. 发明申请

WO2010028314A1 SYSTEMS AND METHODS FOR SUPPORTING OR OCCLUDING A PHYSIOLOGICAL OPENING OR CAVITY 审中-公开
标题翻译：支持或阻止生理开放或开放的系统和方法
公开(公告)号：WO2010028314A1
公开(公告)日：2010-03-11
申请号：PCT/US2009/056133
申请日：2009-09-04
申请人： PULSAR VASCULAR, INC. , GERBERDING, Brent , ABRAMS, Robert M. , CLARKE, Gilbert
发明人： GERBERDING, Brent , ABRAMS, Robert M. , CLARKE, Gilbert
IPC分类号： A61B17/08
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12036 , A61B17/12118 , A61B17/12172 , A61B17/12177 , A61B2017/00778 , A61B2017/00867 , A61B2017/00893 , A61B2017/00898 , A61B2017/12054 , A61F2/06 , A61F2/86 , A61F2/95 , A61F2240/001
摘要： Implantable devices for placement at a cavity or opening such as an aneurysm are disclosed. The implantable devices, in a deployed condition, have a generally inverted U-shaped profile with a curved or angled framework support structure sized and configured for placement in proximity to tissue surrounding the opening and anchoring legs extending proximally from the framework structure sized and configured to contact the wall of a neighboring lumen at opposed locations. Occlusive and semi-occlusive membranes may be associated with the framework support structure and deployed over the opening to provide exclusion of the opening and flow diversion. Proximal anchoring segments providing additional lumen wall surface area contact for the implantable device following deployment may be incorporated.
摘要翻译：公开了用于放置在诸如动脉瘤之类的空腔或开口处的可植入装置。处于展开状态的可植入装置具有大致倒置的U形轮廓，其具有弯曲或成角度的框架支撑结构，其尺寸和构造用于放置在围绕开口的组织附近并且从框架结构向近侧延伸的锚定尺寸和构造成在相对的位置接触相邻内腔的壁。闭塞和半闭塞膜可以与框架支撑结构相关联并且部署在开口上以提供开放和流动分流的排除。可以结合在部署后为可植入装置提供额外的管腔壁表面积接触的近端锚固段。

7. 发明申请

WO2013052920A1 DEVICES, SYSTEMS AND METHODS FOR ENCLOSING AN ANATOMICAL OPENING 审中-公开
标题翻译：用于封闭解剖学开放的装置，系统和方法
公开(公告)号：WO2013052920A1
公开(公告)日：2013-04-11
申请号：PCT/US2012/059133
申请日：2012-10-05
申请人： PULSAR VASCULAR, INC.
发明人： BACHMAN, Anthony , ROUE, Chad , JENSEN, Marc , WALSH, Mike , CAMERON, Scott , GENDREAU, Michael , ABRAMS, Robert, M.
IPC分类号： A61B17/12
CPC分类号： A61B17/12118
摘要： The present technology is directed generally to devices, systems, and methods for enclosing anatomical openings. In several embodiments, an aneurysm device is endovascularly deliverable to a site proximate to an arterial aneurysm. The aneurysm device comprises a closure structure having a distal-facing aspect configured to at least partially occlude the aneurysm and a proximal-facing aspect configured to arch over lumina of an artery. The device further includes a supplemental stabilizer connected to the closure structure and configured to reside in the artery and press outward against a luminal wall thereof. In some embodiments, the device can also include a barrier spanning at least a portion of the distal-facing aspect of the closure structure and configured to further occlude a neck of the aneurysm. In further embodiments, the closure structure can be configured to restrict and/or divert flow to or from the aneurysm.
摘要翻译：本技术一般涉及用于封闭解剖开口的装置，系统和方法。在几个实施例中，动脉瘤装置血管内递送到靠近动脉瘤的部位。动脉瘤装置包括封闭结构，所述封闭结构具有构造成至少部分地闭塞动脉瘤的远侧面部侧面和配置成拱起动脉的管腔的近端侧面。所述装置还包括连接到所述封闭结构并被配置为驻留在所述动脉中并且向外压靠其封闭壁的补充稳定器。在一些实施例中，该装置还可以包括穿过封闭结构的远侧面部分的至少一部分的障碍物并且构造成进一步闭塞动脉瘤的颈部。在另外的实施例中，封闭结构可被配置成限制和/或转移流动或流动动脉瘤。

8. 发明申请

WO2012167156A1 ANEURYSM DEVICES WITH ADDITIONAL ANCHORING MECHANISMS AND ASSOCIATED SYSTEMS AND METHODS 审中-公开
标题翻译：具有附加锚固机构和相关系统和方法的神经元装置
公开(公告)号：WO2012167156A1
公开(公告)日：2012-12-06
申请号：PCT/US2012/040558
申请日：2012-06-01
申请人： PULSAR VASCULAR, INC. , GERBERDING, Brent
发明人： GERBERDING, Brent
IPC分类号： A61B17/12
CPC分类号： A61B17/12172 , A61B17/12118
摘要： The present technology relates to aneurysm devices with additional anchoring mechanisms, and associated systems and methods. In some embodiments, the aneurysm devices are endovascularly deliverable to a site proximate an aneurysm near a parent artery with bifurcating branches. The aneurysm devices can include a closure structure (102) comprising a distal- facing aspect configured to at least partially occlude the aneurysm and a proximal-facing aspect configured to arch over lumina of the bifurcating branches. The devices further include a supplemental stabilizer (103) connected to the closure structure. The supplemental stabilizer is configured to reside in the parent artery. The closure structure includes a hinge point (175) where the closure structure folds to form a loop element configured for anchoring within at least one of the bifurcating branches.
摘要翻译：本技术涉及具有附加锚固机构的动脉瘤装置以及相关的系统和方法。在一些实施例中，动脉瘤装置血管内递送到具有分叉分支的母体动脉附近的动脉瘤附近的部位。动脉瘤装置可以包括封闭结构（102），该封闭结构包括构造成至少部分闭塞动脉瘤的朝向远侧的方面，以及配置成拱顶分叉分支的管腔的近端方面。装置还包括连接到封闭结构的补充稳定器（103）。辅助稳定器被配置为存在于母体动脉中。闭合结构包括铰接点（175），其中封闭结构折叠以形成环形元件，该环形元件构造成用于锚定在至少一个分叉分支中。

9. 发明申请

WO2012167137A1 SYSTEMS AND METHODS FOR CAPTURING AND REMOVING BLOOD CLOTS 审中-公开
标题翻译：用于捕获和移除血液的系统和方法
公开(公告)号：WO2012167137A1
公开(公告)日：2012-12-06
申请号：PCT/US2012/040536
申请日：2012-06-01
申请人： PULSAR VASCULAR, INC. , GERBERDING, Brent , JENSEN, Marc , ABRAMS, Robert, M.
发明人： GERBERDING, Brent , JENSEN, Marc , ABRAMS, Robert, M.
IPC分类号： A61B17/3207 , A61B17/221
CPC分类号： A61B17/320725 , A61B17/221 , A61B2017/2215
摘要： The present technology relates to systems and methods for removingblood clots in blood vessels. In some embodiments, the systems include a clot removal device endovascularly deliverable to a treatment site. The clot removal device includes a capture structure comprising a first arm (140) having a plurality of laterally-extending first arm fins (142) and a second arm (150) having a plurality of laterally-extending second arm fins (152) configured to interleave with the first arm fins. In certain embodiments, the first arm fins are configured in a winged arrangement and the second arm fins are configured in a chevron arrangement. The clot removal device can further include a plurality of protruding peripheral points (156) configured to engage with the clot.
摘要翻译：本技术涉及用于清除血管中血块的系统和方法。在一些实施方案中，所述系统包括血管内递送至治疗部位的凝块清除装置。凝块移除装置包括捕获结构，该捕获结构包括具有多个横向延伸的第一臂翅片（142）的第一臂（140）和具有多个横向延伸的第二臂翅片（152）的第二臂（150）与第一臂翅片交错。在某些实施例中，第一臂翅片被构造成翼形布置，并且第二臂翅片构造为人字形布置。凝块去除装置还可以包括多个突出的外围点（156），其构造成与凝块接合。

10. 发明申请

WO2011029063A3 SYSTEMS AND METHODS FOR ENCLOSING AN ANATOMICAL OPENING 审中-公开
标题翻译：用于封闭解剖学开放的系统和方法
公开(公告)号：WO2011029063A3
公开(公告)日：2011-07-07
申请号：PCT/US2010047908
申请日：2010-09-03
申请人： PULSAR VASCULAR INC , CLARKE GILBERT , GERBERDING BRENT , ABRAMS ROBERT M , MOLAEI MASOUD
发明人： CLARKE GILBERT , GERBERDING BRENT , ABRAMS ROBERT M , MOLAEI MASOUD
IPC分类号： A61B17/12 , A61F2/90
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12118 , A61B17/1214 , A61B17/12145 , A61B17/12172 , A61B17/1219 , A61B2017/00632 , A61B2017/00867 , A61B2017/12054
摘要： Implantable therapeutic devices and methods for endovascular placement of devices at a target site, such an opening at a neck of an aneurysm, are disclosed. Selected embodiments of the present technology have closures (102) that at least partially occlude the neck of an aneurysm to stabilize embolic or coagulative treatment of the aneurysm. In one embodiment, for example, an aneurysm closure device comprises a closure structure (102) and a supplemental stabilizer (103). The closure structure can have a curved portion configured to extend along a first vessel, such as a side branch of a bifurcated vessel that extends along a lateral axis (T). The supplemental stabilizer extends from the closure structure along a longitudinal axis (L) transverse to the lateral axis of the first vessel. The supplemental stabilizer is configured to exert an outward force against a second vessel, such as a parent vessel, that extends transversely to the first vessel.
摘要翻译：公开了用于在靶位置处的装置的血管内放置的可植入治疗装置和方法，例如在动脉瘤颈部的开口。本技术的选择的实施例具有闭合件（102），其至少部分地封闭动脉瘤的颈部以稳定动脉瘤的栓塞或凝固治疗。在一个实施例中，例如，动脉瘤闭合装置包括封闭结构（102）和补充稳定器（103）。闭合结构可以具有弯曲部分，其被构造成沿着第一容器延伸，例如沿着横向轴线（T）延伸的分叉容器的侧分支。补充稳定器沿着横向于第一容器的横向轴线的纵向轴线（L）从封闭结构延伸。辅助稳定器被配置成向横向于第一容器延伸的第二容器（例如母体容器）施加向外的力。

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