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1. 发明申请

WO2013144770A3 A STRUCTURE OF ARTIFICIAL ENDO-URETHRAL SPHINCTER 审中-公开
公开(公告)号：WO2013144770A3
公开(公告)日：2013-10-03
申请号：PCT/IB2013/052156
申请日：2013-03-18
申请人： PINZI, Novello , MAZZOCCHI, Tommaso , GIULIANI, Giuseppe
发明人： PINZI, Novello , MAZZOCCHI, Tommaso , GIULIANI, Giuseppe
IPC分类号： A61F2/00
摘要： A structure (140) of artificial endo-urethral sphincter for treating the urinary incontinence comprising at least one hollow rigid body (71), configured for being fixed within the walls (3) of the urethral-bladder lumen of a patient, inside it being provided: a longitudinal channel (11'); a valve element (13) housed within the longitudinal channel (11'); a closure means for moving the valve element (13) between a closed configuration and an open configuration. In a first aspect of the invention, the structure comprises a safety element (16) arranged within the longitudinal channel (11') downstream of the valve element (13), also comprises a block means structured for turning between a block configuration and a release configuration, where the safety element (16) is configured for preventing an unwanted / allowing a massive flow of urine (99), respectively, through the valve element (13). The structure prevents unwanted urine leakage, in particular urine leakages due to a seal defect of the sphincter, or in the case of an uncontrolled increase of the intravesical pressure due to coughs and efforts of any other nature. In an exemplary embodiment, a safety abutment member (16) is provided on a valve element (13) comprising preferably shell- shaped (34) resilient walls, which in the release configuration is at a distance from the valve element (13) and enables the latter to open. A return elastic element (14) may be arranged for firmly keeping the safety element (16) in the block configuration. In a second aspect of the invention, the safety element (16) may comprise, at an own end (21,21'), a magnetically sensitive element (15), configured such that, by arranging an external (electro)magnetic element (17) with the same polarization direction, a magnetic coupling is formed of the two elements (15,17) and the safety element (16) turns to the release configuration.

2. 发明申请

WO2013144770A2 A STRUCTURE OF ARTIFICIAL ENDO-URETHRAL SPHINCTER 审中-公开
标题翻译：人造内耳结构的结构
公开(公告)号：WO2013144770A2
公开(公告)日：2013-10-03
申请号：PCT/IB2013052156
申请日：2013-03-18
申请人： PINZI NOVELLO , MAZZOCCHI TOMMASO , GIULIANI GIUSEPPE
发明人： PINZI NOVELLO , MAZZOCCHI TOMMASO , GIULIANI GIUSEPPE
CPC分类号： A61F2/0022 , A61F2/0036 , A61F2210/009
摘要： A structure (140) of artificial endo-urethral sphincter for treating the urinary incontinence comprising at least one hollow rigid body (71), configured for being fixed within the walls (3) of the urethral-bladder lumen of a patient, inside it being provided: a longitudinal channel (11'); a valve element (13) housed within the longitudinal channel (11'); a closure means for moving the valve element (13) between a closed configuration and an open configuration. In a first aspect of the invention, the structure comprises a safety element (16) arranged within the longitudinal channel (11') downstream of the valve element (13), also comprises a block means structured for turning between a block configuration and a release configuration, where the safety element (16) is configured for preventing an unwanted / allowing a massive flow of urine (99), respectively, through the valve element (13). The structure prevents unwanted urine leakage, in particular urine leakages due to a seal defect of the sphincter, or in the case of an uncontrolled increase of the intravesical pressure due to coughs and efforts of any other nature. In an exemplary embodiment, a safety abutment member (16) is provided on a valve element (13) comprising preferably shell- shaped (34) resilient walls, which in the release configuration is at a distance from the valve element (13) and enables the latter to open. A return elastic element (14) may be arranged for firmly keeping the safety element (16) in the block configuration. In a second aspect of the invention, the safety element (16) may comprise, at an own end (21,21'), a magnetically sensitive element (15), configured such that, by arranging an external (electro)magnetic element (17) with the same polarization direction, a magnetic coupling is formed of the two elements (15,17) and the safety element (16) turns to the release configuration.
摘要翻译：一种用于治疗尿失禁的人造内尿道括约肌的结构（140），包括至少一个中空刚体（71），其构造成固定在患者的尿道 - 膀胱腔的壁（3）内，其内部是提供：纵向通道（11'）; 容纳在所述纵向通道（11'）内的阀元件（13）; 用于在闭合构型和打开构型之间移动阀元件（13）的闭合装置。在本发明的第一方面，该结构包括布置在阀元件（13）下游的纵向通道（11'）内的安全元件（16），还包括被构造用于在块构造和释放配置，其中安全元件（16）被配置为分别防止通过阀元件（13）不期望/允许大量尿（99）的流动。该结构防止不必要的尿液泄漏，特别是由于括约肌的密封缺陷引起的尿液泄漏，或者由于咳嗽和任何其他性质的努力而引起的膀胱内压力的不受控制的增加。在示例性实施例中，安全抵靠构件（16）设置在阀元件（13）上，该阀元件（13）优选地包括壳形（34）弹性壁，其在释放构造中与阀元件（13）相距一定距离，后者打开。可以布置返回弹性元件（14）以将安全元件（16）牢固地保持在块状构造中。在本发明的第二方面中，安全元件（16）可以在自身端（21,21'）处包括磁感应元件（15），其构造成通过将外部（电）磁性元件 17），具有相同的偏振方向，由两个元件（15,17）形成磁耦合，并且安全元件（16）变为释放构造。

3. 发明申请

WO2012120326A1 STRUCTURE OF ARTIFICIAL URINARY BLADDER 审中-公开
标题翻译：人造尿布结构
公开(公告)号：WO2012120326A1
公开(公告)日：2012-09-13
申请号：PCT/IB2011/001558
申请日：2011-07-04
申请人： PINZI, Novello , MAZZOCCHI, Tommaso , GIULIANI, Giuseppe
发明人： PINZI, Novello , MAZZOCCHI, Tommaso , GIULIANI, Giuseppe
IPC分类号： A61F2/00 , A61F2/04
CPC分类号： A61F2/042 , A61F2/0036 , A61F2210/009
摘要： A structure of artificial urinary bladder (1 ) comprises at least one inlet (11a and lib) that is adapted to be put in communication with a respective ureter (110a and 110b), and an outlet (13) that is adapted to be put in communication with the urethra (130) of the patient. The hollow container body (10) is made of a flexible material and is arranged to turn from an urine containing configuration (50) to a squeezed discharge configuration that causes a discharge of urine (50) through the outlet (13). A valve is provided (20) at the outlet (13) and actuating means (30) of the valve (20) is provided movable between a closed position for closing outlet (13), when the container (10) is in the urine containing configuration, and an open position, when the hollow flexible container body (10) is in the squeezed discharge configuration. Furthermore, a squeezing means (60) of the hollow container body (10) can be present that is adapted to pass from a rest position, simultaneously to the valve (20) staying in the closed position, to a position of squeezing the hollow container body (10), simultaneously to the valve (20) staying in the open position.
摘要翻译：人造尿囊（1）的结构包括适于与相应的输尿管（110a和110b）连通的至少一个入口（11a和11b）和适于放入与患者的尿道（130）通信。中空容器主体10由柔性材料制成，并被布置成从尿液构造（50）转向通过出口（13）排出尿液（50）的挤压排放构型。在出口（13）处设有阀门（20），阀门（20）的致动装置（30）设置为可在关闭出口（13）的关闭位置之间移动，当容器（10）在尿液中时构造和打开位置，当中空柔性容器主体（10）处于挤压排放构型时。此外，可以存在中空容器主体（10）的挤压装置（60），该挤压装置（60）适于从静止位置同时传递到保持在关闭位置的阀（20）到挤压中空容器的位置主体（10）同时到位于打开位置的阀门（20）。

4. 发明申请

WO2017145130A1 AN ARTIFICIAL BLADDER, AND A PROCESS FOR ITS MANUFACTURE 审中-公开
标题翻译：人造膀胱，及其制造过程
公开(公告)号：WO2017145130A1
公开(公告)日：2017-08-31
申请号：PCT/IB2017/051133
申请日：2017-02-27
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA , PINZI, Novello
发明人： PINZI, Novello , RICOTTI, Leonardo , MAZZOCCHI, Tommaso , FONTANA, Rossella , MENCIASSI, Arianna , IACOVACCI, Veronica
IPC分类号： A61F2/04
CPC分类号： A61F2/042 , A61F2210/0076 , A61F2230/005 , A61F2240/004
摘要： The present invention relates to an implantable medical device for collecting and discharging biological urinary fluids, for example an artificial bladder, which by virtue of a multilayer body having a particular shape of the inner surface, allows reproducing the natural organ tissue performance especially in terms of flexibility and consequent variability of the inner volume, further exhibiting high stability and urine resistance in the long term.
摘要翻译：本发明涉及用于收集和排出生物尿液的可植入医疗装置，例如人造膀胱，其借助具有特定形状的内表面的多层体允许再生天然器官组织的性能，特别是在灵活性和内部容积的随之变化方面，进一步表现出长期的高稳定性和尿液抵抗力。

5. 发明申请

WO2017145128A1 ARTIFICIAL BLADDER 审中-公开
标题翻译：人工膀胱
公开(公告)号：WO2017145128A1
公开(公告)日：2017-08-31
申请号：PCT/IB2017/051130
申请日：2017-02-27
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA , PINZI, Novello
发明人： PINZI, Novello , RICOTTI, Leonardo , MAZZOCCHI, Tommaso , FONTANA, Rossella , MENCIASSI, Arianna , IACOVACCI, Veronica
IPC分类号： A61F2/04
CPC分类号： A61F2/042 , A61F2210/0076
摘要： The present invention relates to an artificial bladder for collecting and discharging biological urinary fluids, provided with high stability and resistance to urine over the long periods, also being able to expand and contract with a variation of its inner volume, without the constituent material to be subject to stretching or deformation under the pressure of the urinary fluids.
摘要翻译：本发明涉及一种用于收集和排出生物尿液的人造膀胱，其长期具有高稳定性和耐尿性，并且能够随其内部的变化而膨胀和收缩体积，没有组成材料在尿液压力下受到拉伸或变形。

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