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    • 1. 发明申请
    • BIOSENSOR, PALM-SIZED DEVICE AND METHOD BASED ON MAGNETIC RESONANCE RELAXOMETRY
    • 生物传感器,PALM尺寸的设备和基于磁共振放大的方法
    • WO2012118442A1
    • 2012-09-07
    • PCT/SG2012/000056
    • 2012-02-27
    • MASSACHUSETTS INSTITUTE OF TECHNOLOGYPENG, Weng KungHAN, JongyoonCHEN, Lan
    • PENG, Weng KungHAN, Jongyoon
    • A61B5/055G01R33/20
    • G01R33/448A61B5/055G01N24/08G01R33/302G01R33/3808G01R33/383G01R33/465G01R33/4828G01R33/50G01R33/543G01R33/546
    • In accordance with one aspect of this disclosure, there is provided a device for performing magnetic resonance relaxometry. The device comprises a radio-frequency spectrometer comprising at least one field-programmable gate array chip; a power amplifier electrically connected with the radio-frequency spectrometer and amplifying an electrical output of the radio-frequency spectrometer, thereby producing an amplified electrical signal comprising between about 0.1 Watts and about 10 Watts power; a duplexer configured to isolate the radio-frequency spectrometer from the amplified electrical signal during a receiving mode of the device; a radio-frequency detection probe configured to transmit radio-frequency electromagnetic radiation to excite nuclei under resonance during a transmission mode of the device, the radio-frequency detection probe comprising a detection coil comprising an inner diameter of less than about 1 millimeter; and at least one magnet supplying an external magnetic field to a detection region of the radio-frequency detection probe, the external magnetic field being less than about 3 Tesla.
    • 根据本公开的一个方面,提供了一种用于执行磁共振弛豫测量的装置。 该装置包括一个包括至少一个现场可编程门阵列芯片的射频光谱仪; 功率放大器,其与所述射频光谱仪电连接并放大所述射频光谱仪的电输出,从而产生包括约0.1瓦至约10瓦功率之间的放大电信号; 双工器,被配置为在所述设备的接收模式期间将所述射频频谱仪与放大的电信号隔离; 射频检测探头,被配置为在所述设备的传输模式期间传输射频电磁辐射以在谐振下激发核,所述射频检测探针包括包含小于约1毫米的内径的检测线圈; 以及向所述射频检测探针的检测区域提供外部磁场的至少一个磁体,所述外部磁场小于约3特斯拉。