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1. 发明申请

WO2010051425A2 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
公开(公告)号：WO2010051425A2
公开(公告)日：2010-05-06
申请号：PCT/US2009/062719
申请日：2009-10-30
申请人： MEDTRONIC, INC. , KRAUSE, Paul, G. , BURNES, John, E. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
发明人： KRAUSE, Paul, G. , BURNES, John, E. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/36114 , A61N1/36185 , A61N1/3686 , A61N1/3688
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.

2. 发明申请

WO2010051424A1 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
公开(公告)号：WO2010051424A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062718
申请日：2009-10-30
申请人： MEDTRONIC, INC. , BURNES, John, E. , KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , PEICHEL, David, J. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
发明人： BURNES, John, E. , KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , PEICHEL, David, J. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
IPC分类号： A61N1/36 , A61B5/053 , A61N1/365 , A61N1/368 , A61N1/372 , A61N1/39
CPC分类号： A61N1/3605 , A61N1/36114 , A61N1/36521 , A61N1/37 , A61N1/37258 , A61N1/37288
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.

3. 发明申请

WO2010051392A1 THERAPY MODULE CROSSTALK MITIGATION 审中-公开
标题翻译：治疗模块CROSSTALK减缓
公开(公告)号：WO2010051392A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062650
申请日：2009-10-29
申请人： MEDTRONIC, INC. , DONOFRIO, William, T. , KRAUSE, Paul, G. , ARNE, Gerald, P. , BURNES, John, E. , PEICHEL, David, J. , ZHOU, Xiaohong
发明人： DONOFRIO, William, T. , KRAUSE, Paul, G. , ARNE, Gerald, P. , BURNES, John, E. , PEICHEL, David, J. , ZHOU, Xiaohong
IPC分类号： A61N1/36 , A61N1/372
CPC分类号： A61N1/37288 , A61N1/36114
摘要： A first implantable medical device (IMD) implanted within a patient may communicate with a second IMD implanted within the patient by encoding information in an electrical stimulation signal. The delivery of the electrical stimulation signal may provide therapeutic benefits to the patient. The second IMD may sense the electrical stimulation signal, which may be presented as an artifact in a sensed cardiac signal, and process the sensed signal to retrieve the encoded information. The second IMD may modify its operation based on the received therapy information. Crosstalk between the first and second IMDs may be reduced using various techniques described herein. For example, the first IMD may generate the electrical stimulation signal to include a spread spectrum energy distribution or a predetermined signal signature. The second IMD may effectively remove a least some of the signal artifact in a sensed cardiac signal based on the predetermined signal signature.
摘要翻译：植入在患者体内的第一可植入医疗装置（IMD）可以通过对电刺激信号中的信息进行编码来与植入患者内的第二IMD进行通信。电刺激信号的传递可以为患者提供治疗益处。第二IMD可以感测电刺激信号，其可以被呈现为感测到的心脏信号中的伪像，并且处理感测到的信号以检索经编码的信息。第二IMD可以基于接收到的治疗信息修改其操作。可以使用本文所述的各种技术来减少第一和第二IMD之间的串扰。例如，第一IMD可以产生电刺激信号以包括扩频能量分布或预定信号特征。基于预定的信号签名，第二IMD可以有效地去除感测到的心脏信号中的至少一些信号伪像。

4. 发明申请

WO2010051317A1 ISOLATION OF SENSING AND STIMULATION CIRCUITRY 审中-公开
标题翻译：感应和刺激电路的隔离
公开(公告)号：WO2010051317A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062404
申请日：2009-10-28
申请人： MEDTRONIC, INC. , DONOFRIO, William, T. , KRAUSE, Paul, G. , REINKE, James, D. , PEICHEL, David, J.
发明人： DONOFRIO, William, T. , KRAUSE, Paul, G. , REINKE, James, D. , PEICHEL, David, J.
IPC分类号： A61N1/37 , A61N1/08 , A61N1/39 , A61N1/378
CPC分类号： A61N1/37 , A61N1/36125 , A61N1/3718 , A61N1/378 , A61N1/3962
摘要： The disclosure describes techniques of reducing or eliminating a commonality between two modules within the same implantable medical device. Each module within the implantable medical device provides therapy to a patient. The commonality between the two modules exists due to at least one common component shared by the two modules. The commonality between the two modules may create common-mode interference and a shunt current. In accordance with this disclosure, various isolation circuits located at various locations are disclosed to reduce or eliminate the commonality between the two modules. The reduction or elimination of the commonality between the two modules may reduce or eliminate common-mode interference and the shunt current.
摘要翻译：本公开描述了减少或消除同一可植入医疗设备内的两个模块之间的共性的技术。可植入医疗装置内的每个模块为患者提供治疗。由于两个模块共享至少一个公共组件，因此存在两个模块之间的共同性。两个模块之间的共同性可能会产生共模干扰和分流电流。根据本公开，公开了位于各个位置的各种隔离电路以减少或消除两个模块之间的共同性。减少或消除两个模块之间的共性可以减少或消除共模干扰和分路电流。

5. 发明申请

WO2012102747A1 DISABLING AN IMPLANTED MEDICAL DEVICE WITH ANOTHER MEDICAL DEVICE 审中-公开
标题翻译：使用其他医疗设备禁用植入式医疗设备
公开(公告)号：WO2012102747A1
公开(公告)日：2012-08-02
申请号：PCT/US2011/034655
申请日：2011-04-29
申请人： MEDTRONIC, INC. , PEICHEL, David, J. , LI, Wing, Kam , HAIDER, Gregory, A. , DVORAK, David, P.
发明人： PEICHEL, David, J. , LI, Wing, Kam , HAIDER, Gregory, A. , DVORAK, David, P.
IPC分类号： A61N1/372
CPC分类号： A61N1/37205 , A61N1/3627 , A61N1/3684 , A61N1/37288 , A61N1/3756
摘要： Various techniques for disabling a first implantable medical device (IMD) by modulation of therapeutic electrical stimulation delivered by a second medical device are described. One example method includes delivering therapeutic electrical stimulation from a more recently implanted second IMD at a higher average rate than the previously implanted first IMD so that only the more recently implanted IMD will administer therapy, and modulating stimulation by the more recently implanted IMD in order to send a disable command to the previously implanted IMD.
摘要翻译：描述通过调制由第二医疗装置传递的治疗性电刺激来禁用第一可植入医疗装置（IMD）的各种技术。一个示例性方法包括以比先前植入的第一IMD更高的平均速率从最近植入的第二IMD递送治疗性电刺激，使得仅最近植入的IMD将施用治疗，并且通过最近植入的IMD调节刺激，以便向以前植入的IMD发送禁用命令。

6. 发明申请

WO2010051426A1 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
公开(公告)号：WO2010051426A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062720
申请日：2009-10-30
申请人： MEDTRONIC, INC. , KRAUSE, Paul, G. , BURNES, John, E. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D.
发明人： KRAUSE, Paul, G. , BURNES, John, E. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D.
IPC分类号： A61N1/36 , A61N1/372
CPC分类号： A61N1/08 , A61N1/36114 , A61N1/37 , A61N1/37258 , A61N1/37288
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.

7. 发明申请

WO2010051389A1 COMMUNICATION BETWEEN IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：可植入医疗器械之间的通讯
公开(公告)号：WO2010051389A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062639
申请日：2009-10-29
申请人： MEDTRONIC, INC. , KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , BURNS, John, E. , PEICHEL, David, J. , ZHOU, Xiaohong
发明人： KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , BURNS, John, E. , PEICHEL, David, J. , ZHOU, Xiaohong
IPC分类号： A61N1/372 , A61N1/37 , A61N1/362
CPC分类号： A61N1/37288 , A61N1/36082 , A61N1/362 , A61N1/3706 , A61N1/37217 , A61N1/3727
摘要： A first implantable medical device (IMD) implanted within a patient may communicate with a second IMD implanted within the patient by encoding information in an electrical stimulation signal. The delivery of the electrical stimulation signal may provide therapeutic benefits to the patient. The second IMD may sense the electrical stimulation signal, which may be presented as an artifact in a sensed cardiac signal, and process the sensed signal to retrieve the encoded information. The second IMD may modify its operation based on the received therapy information. Crosstalk between the first and second IMDs may be reduced using various techniques described herein. For example, the first IMD may generate the electrical stimulation signal to include a spread spectrum energy distribution or a predetermined signal signature. The second IMD may effectively remove a least some of the signal artifact in a sensed cardiac signal based on the predetermined signal signature.
摘要翻译：植入在患者体内的第一可植入医疗装置（IMD）可以通过对电刺激信号中的信息进行编码来与植入患者内的第二IMD进行通信。电刺激信号的传递可以为患者提供治疗益处。第二IMD可以感测电刺激信号，其可以被呈现为感测到的心脏信号中的伪像，并且处理感测到的信号以检索经编码的信息。第二IMD可以基于接收到的治疗信息修改其操作。可以使用本文所述的各种技术来减少第一和第二IMD之间的串扰。例如，第一IMD可以产生电刺激信号以包括扩频能量分布或预定信号特征。基于预定的信号签名，第二IMD可以有效地去除感测到的心脏信号中的至少一些信号伪像。

8. 发明申请

WO2010051385A1 IMPLANTABLE MEDICAL DEVICE INCLUDING EXTRAVASCULAR CARDIAC STIMULATION AND NEUROSTIMULATION CAPABILITIES 审中-公开
标题翻译：包括超声心动图刺激和神经修复能力的可植入医疗装置
公开(公告)号：WO2010051385A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062615
申请日：2009-10-29
申请人： MEDTRONIC, INC. , BURNES, John, E. , ZILLMER, Chris , KRAUSE, Paul, G. , ARNE, Gerald, P. , DAVIS, Timothy , PEICHEL, David, J. , REINKE, James, D. , DONOFRIO, William, T. , ZHOU, Xiaohong
发明人： BURNES, John, E. , ZILLMER, Chris , KRAUSE, Paul, G. , ARNE, Gerald, P. , DAVIS, Timothy , PEICHEL, David, J. , REINKE, James, D. , DONOFRIO, William, T. , ZHOU, Xiaohong
IPC分类号： A61N1/36 , A61N1/362 , A61N1/05 , A61N1/39 , A61N1/365 , A61B5/046
CPC分类号： A61N1/0504 , A61B5/046 , A61N1/0587 , A61N1/36114 , A61N1/3622 , A61N1/365 , A61N1/3962
摘要： An implantable medical device may deliver pacing, cardioversion, and/or defibrillation stimulation to a heart of a patient via extravascular electrodes and delivers electrical stimulation to a nonmyocardial tissue site to modulate the autonomic nervous system of the patient. The implantable medical device may include a cardiac therapy module that generates and delivers at least one of pacing, cardioversion, or defibrillation therapy to a patient via an extravascular electrode, and a neurostimulation therapy module that generates and delivers a neurostimulation signal to the patient via a neurostimulation electrode. The cardiac therapy module and neurostimulation therapy module may be disposed in a common housing of the medical device. In some examples, at least one common lead may electrically couple the neurostimulation electrode and the extravascular electrode to the neurostimulation and cardiac therapy modules, respectively.
摘要翻译：可植入医疗装置可通过血管外电极向患者的心脏输送起搏，心脏复律和/或除颤刺激，并将电刺激递送至非心肌组织部位以调节患者的自主神经系统。可植入医疗装置可以包括心脏治疗模块，该心脏治疗模块通过血管内电极产生并向患者输送起搏，心脏复律或除颤疗法中的至少一种，以及神经刺激治疗模块，其通过经由血管内电极产生和递送神经刺激信号给患者神经刺激电极。心脏治疗模块和神经刺激治疗模块可以设置在医疗装置的公共壳体中。在一些示例中，至少一个共同引线可以将神经刺激电极和血管外电极分别电耦合到神经刺激和心脏治疗模块。

9. 发明申请

WO2012103433A1 COMMUNICATION DIPOLE FOR IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于可植入医疗器械的通信用DIPOLE
公开(公告)号：WO2012103433A1
公开(公告)日：2012-08-02
申请号：PCT/US2012/022889
申请日：2012-01-27
申请人： MEDTRONIC, INC. , ROBERTS, Jonathan P. , CINBIS, Can , PEICHEL, David J. , ALLAN, James C. , REINKE, James D. , MOTHILAL, Kamal Deep , GRISWOLD, Erik , PATRAS, George
发明人： ROBERTS, Jonathan P. , CINBIS, Can , PEICHEL, David J. , ALLAN, James C. , REINKE, James D. , MOTHILAL, Kamal Deep , GRISWOLD, Erik , PATRAS, George
IPC分类号： A61N1/372 , H04B13/00
CPC分类号： A61N1/37205 , A61B5/0028 , A61B5/0031 , A61B5/0215 , A61B5/6876 , A61B5/6882 , A61B2562/0247 , A61N1/37217 , H04B13/005
摘要： This disclosure is directed to an implantable medical device having a communication dipole configured in accordance with the techniques described herein. In one example, the disclosure is directed to an implantable medical device comprising a housing that encloses at least a communication module, a first electrode of a communication dipole electrically coupled to the communication module and an electrically conductive fixation mechanism that is electrically coupled to a portion of the housing and wherein a portion of the fixation mechanism is configured to function as at least part of a second electrode of the communication dipole. The electrically conductive fixation mechanism includes a dielectric material that covers at least part of a surface of the fixation mechanism. The communication module is configured to transmit or receive a modulated signal between the first electrode and second electrode of the communication dipole.
摘要翻译：本公开涉及具有根据本文所描述的技术配置的通信偶极子的可植入医疗装置。在一个示例中，本公开涉及可植入医疗装置，其包括壳体，该壳体至少包围通信模块，电耦合到通信模块的通信偶极子的第一电极和电连接到通信模块的部分的导电固定机构并且其中所述固定机构的一部分被配置为用作所述通信偶极子的第二电极的至少一部分。导电固定机构包括覆盖固定机构的表面的至少一部分的电介质材料。通信模块被配置为在通信偶极子的第一电极和第二电极之间发送或接收调制信号。

10. 发明申请

WO2012102846A1 ACCELEROMETER FEEDBACK CONTROL LOOP FOR PATIENT ALERT 审中-公开
标题翻译：加速器反馈控制环路用于患者提示
公开(公告)号：WO2012102846A1
公开(公告)日：2012-08-02
申请号：PCT/US2012/020611
申请日：2012-01-09
申请人： MEDTRONIC, INC. , PEICHEL, David J. , WERNER, Lewis J. , KRAUSE, Paul G. , BARNHISER, Thomas M. , WYSZYNSKI, Ryan D.
发明人： PEICHEL, David J. , WERNER, Lewis J. , KRAUSE, Paul G. , BARNHISER, Thomas M. , WYSZYNSKI, Ryan D.
IPC分类号： A61N1/372
CPC分类号： A61N1/37258 , G16H40/63
摘要： A system and associated method alert a patient of a condition detected by an implanted medical device by delivering an alert signal to cause a motion within the patient's body in response to detecting the condition. An accelerometer signal is measured during the alert signal delivery. Accelerometer signal measurements are compared to a threshold. A parameter controlling the alert signal is adjusted to maintain the accelerometer signal within a range of the threshold.
摘要翻译：系统和相关联的方法通过递送警报信号来向患者通知由植入的医疗装置检测到的状况，以响应于检测到该状况而引起患者体内的运动。在警报信号传送期间测量加速度计信号。加速度计信号测量值与阈值进行比较。调整控制警报信号的参数，以将加速度计信号保持在阈值的范围内。

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