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1. 发明申请

WO2012099448A2 RECOMBINANT ADENOVIRUS EXPRESSING aA-CRYSTALLIN GENE AND GENE THERAPY FOR RETINAL VASCULAR DISEASE USING SAME 审中-公开
标题翻译：重组腺病毒表达a-CRYSTALLIN基因和基因治疗用于使用其的视网膜病变
公开(公告)号：WO2012099448A2
公开(公告)日：2012-07-26
申请号：PCT/KR2012000580
申请日：2012-01-20
申请人： NAT UNIV GYEONGSANG IACF , CHOI WAN SUNG , WHANG EUN MI , PARK JAE YONG , CHO GYEONG JAE , KIM YOUNG HEE , PARK SO YUN
发明人： CHOI WAN SUNG , WHANG EUN MI , PARK JAE YONG , CHO GYEONG JAE , KIM YOUNG HEE , PARK SO YUN
IPC分类号： C12N7/01 , A61K35/76 , A61P27/02 , C12N15/861
CPC分类号： A61K35/761 , A61K38/1709 , A61K48/005 , C12N15/86 , C12N2710/10343 , C12N2710/10371
摘要： The present invention relates to recombinant adenovirus expressing aA-crystallin gene and to a gene therapy for retinal vascular disease using the recombinant adenovirus. The gene therapy using the recombinant adenovirus including aA-crystallin gene according to the present invention increases the expression level of aA-crystallin gene in injured of retinal pericytes to inhibit apoptosis and loss of pericytes, retinal vascular leakage, and leukocyte adherence in peripheral retinal vessels so as to protect pericytes. Therefore, the gene therapy using the recombinant adenovirus including aA-crystallin gene according to the present invention may be valuably used in the prevention and treatment of various retinal vascular diseases such as diabetic retinopathy.
摘要翻译：本发明涉及使用重组腺病毒表达A-晶状蛋白基因的重组腺病毒和用于视网膜血管疾病的基因治疗。使用包含本发明的A-晶状蛋白基因的重组腺病毒的基因治疗增加视网膜周细胞损伤中的A-晶状蛋白基因的表达水平，以抑制外周视网膜血管中的细胞凋亡和周细胞的损失，视网膜血管渗漏和白细胞粘附以保护周边细胞。因此，使用包含本发明的A-晶状蛋白基因的重组腺病毒的基因治疗可以有价值地用于预防和治疗各种视网膜血管疾病如糖尿病性视网膜病变。

2. 发明申请

WO2011010870A2 GENETIC MARKER FOR PREDICTING THE SURVIVAL OF A PATIENT WITH EARLY-STAGE LUNG CANCER, AND METHOD FOR PREDICTING SURVIVAL USING SAME 审中-公开
标题翻译：用于预测患有早期肺癌患者存活率的遗传标记物和使用相同方法预测生存率
公开(公告)号：WO2011010870A2
公开(公告)日：2011-01-27
申请号：PCT/KR2010004779
申请日：2010-07-21
申请人： LEE MYUNG-HOON , PARK JAE YONG , KIM IN SAN
发明人： LEE MYUNG-HOON , PARK JAE YONG , KIM IN SAN
IPC分类号： C12Q1/68 , C12N15/12 , G01N33/574
CPC分类号： C12N9/6475 , C12Q1/6886 , C12Q2600/118 , C12Q2600/156
摘要： The present invention relates to a marker for predicting the risk of lung cancer and predicting a prognosis for the survival of a patient with lung cancer using the polymorphism of the CASP7 and/or CASP9 gene(s), and to a method for predicting the risk of lung cancer and predicting a prognosis for survival of a lung cancer patient using the marker. More particularly, the present invention relates to a composition for predicting the risk of lung cancer and predicting a prognosis for the survival of a patient with lung cancer on the basis of the polymorphism of the CASP7 and/or CASP9 gene(s), to a kit for predicting the risk of lung cancer and predicting a prognosis for the survival of a lung cancer patient using the composition, to a microarray, and to a method for predicting the risk of lung cancer and predicting a prognosis for the survival of a lung cancer patient.
摘要翻译：本发明涉及使用CASP7和/或CASP9基因的多态性预测肺癌风险和预测肺癌患者存活预后的标记物，以及预测风险的方法使用该标记预测肺癌患者的生存预后。更具体地说，本发明涉及用于基于CASP7和/或CASP9基因的多态性预测肺癌风险并预测肺癌患者存活预后的组合物，使用该组合物预测肺癌患者风险和预测肺癌患者存活预后的试剂盒，微阵列，以及预测肺癌风险和预测肺癌存活预后的方法患者。

3. 发明申请

WO2008140209A1 SYSTEM AND METHOD FOR PROVIDING PACKET NETWORK-BASED MULTIMEDIA RINGBACK TONE SERVICE 审中-公开
标题翻译：用于提供基于分组网络的多媒体铃声服务的系统和方法
公开(公告)号：WO2008140209A1
公开(公告)日：2008-11-20
申请号：PCT/KR2008/002575
申请日：2008-05-08
申请人： SK TELECOM CO., LTD. , LEE, Won Jun , PARK, Jae Yong , KIM, Ki Mun , KIM, Min Seok , JOO, Young Ho
发明人： LEE, Won Jun , PARK, Jae Yong , KIM, Ki Mun , KIM, Min Seok , JOO, Young Ho
IPC分类号： H04Q7/24
CPC分类号： H04M3/42017 , H04W4/16
摘要： Disclosed herein is a system and method for providing a packet network-based MRBT service. In the method, when an originating MSC (110) requests call termination location information from an HLR (120), the HLR transmits an MRBT service request message, including a calling number and a called number, to an MRBT server (140). The MRBT server returns an MRBT service response message, including URL of MRBT content, to the HLR. The HLR transmits a call termination location information response message to the originating MSC, with MRBT service ID information and called party MRBT content URL information included in the call termination location information response message. The originating MSC (110) transmits called party MRBT content URL information to an originating MS (100) on a basis of the MRBT service ID information. The originating MS accesses the MRBT content URL, downloads relevant MRBT content, and plays and stores the MRBT content.
摘要翻译：本文公开了一种用于提供基于分组网络的MRBT服务的系统和方法。在该方法中，当起始MSC（110）从HLR（120）请求呼叫终止位置信息时，HLR向MRBT服务器（140）发送包括呼叫号码和被叫号码的MRBT服务请求消息。 MRBT服务器向HLR返回包括MRBT内容的URL的MRBT服务响应消息。 HLR向起始MSC发送呼叫终止位置信息响应消息，其中包括在呼叫终止位置信息响应消息中的MRBT服务ID信息和被叫方MRBT内容URL信息。始发MSC（110）基于MRBT服务ID信息向主叫MS（100）发送被叫方MRBT内容URL信息。始发MS访问MRBT内容URL，下载相关MRBT内容，并播放和存储MRBT内容。

4. 发明申请

WO2008130164A1 A BLUETOOTH DEVICE HAVING A MEMORY AND METHOD THEREFOR 审中-公开
标题翻译：具有记忆的蓝牙设备及其方法
公开(公告)号：WO2008130164A1
公开(公告)日：2008-10-30
申请号：PCT/KR2008002223
申请日：2008-04-18
申请人： PARK JAE YONG
发明人： PARK JAE YONG
IPC分类号： H04B1/40 , H04B7/24
CPC分类号： H04M1/6066 , H04M2250/02 , H04M2250/64
摘要： The present invention relates to a broadcast receiver, and more particularly, to a method for au tomatically extracting specific sections of a moving picture which a user wishes to record and for editing the extracted sections and a broadcast receiver adopting the same. [MAIN DRAWING] FIG. 2 [INDEX WORDS] Bluetooth, mobile communication terminal, Bluetooth headset, memory, application
摘要翻译：广播接收机技术领域本发明涉及一种广播接收机，更具体地，涉及一种用于自动提取用户希望记录的运动图像的特定部分并用于编辑所提取的部分的方法以及采用该节目的广播接收机的方法。 [主图] 2 [索引]蓝牙，移动通信终端，蓝牙耳机，内存，应用程序

5. 发明申请

WO2004087193A1 USE OF A PEPTIDE THAT INTERACTS WITH ALPHA V BETA3 INTEGRIN OF ENDOTHELIAL CELL 审中-公开
标题翻译：使用与ALPHA V BETA3内皮细胞相互作用的肽
公开(公告)号：WO2004087193A1
公开(公告)日：2004-10-14
申请号：PCT/KR2004/000774
申请日：2004-04-02
申请人： REGEN BIOTECH INC.. , NAM, Ju-Ock , KIM, Jung-Eun , JEONG, Ha-Won , LEE, Sung-Jin , LEE, Byung-Heon , CHOI, Je-Yong , PARK, Rang-Woon , PARK, Jae-Yong , KIM, In-San
发明人： NAM, Ju-Ock , KIM, Jung-Eun , JEONG, Ha-Won , LEE, Sung-Jin , LEE, Byung-Heon , CHOI, Je-Yong , PARK, Rang-Woon , PARK, Jae-Yong , KIM, In-San
IPC分类号： A61K38/16
CPC分类号： A61K38/10
摘要： The present invention relates to the novel use of a peptide that interacts with the αvβ3 integrin of endothelial cells. More particularly, the invention relates to a method for inhibiting endothelial cell adhesion, endothelial cell migration and/or angiogenesis, using a peptide consisting of at least 18 amino acids, comprising tyrosine-histidine (YH) or asparagine-histidine (NH), and at least three hydrophobic amino acids with bulky side chains; or equivalents thereof. Furthermore, the invention provides a method for treating or preventing angiogenesis-related diseases, using the peptide.
摘要翻译：本发明涉及与内皮细胞的alphavbeta3整联蛋白相互作用的肽的新用途。更具体地说，本发明涉及使用包含酪氨酸 - 组氨酸（YH）或天冬酰胺 - 组氨酸（NH）的至少18个氨基酸的肽来抑制内皮细胞粘附，内皮细胞迁移和/或血管发生的方法，以及至少三个具有庞大侧链的疏水性氨基酸; 或其等同物。此外，本发明提供了使用肽治疗或预防血管生成相关疾病的方法。

6. 发明申请

WO2002064808A1 METHOD FOR L-THREONINE PRODUCTION 审中-公开
标题翻译： L-螺旋藻生产方法
公开(公告)号：WO2002064808A1
公开(公告)日：2002-08-22
申请号：PCT/KR2002/000230
申请日：2002-02-14
申请人： CHEIL JEDANG CORPORATION , NOH, Kap-Soo , KIM, Yeong-Chul , PARK, Jae-Yong , KIM, Dai-Chul , LEE, Jin-Ho , OK, Seung-Han
发明人： NOH, Kap-Soo , KIM, Yeong-Chul , PARK, Jae-Yong , KIM, Dai-Chul , LEE, Jin-Ho , OK, Seung-Han
IPC分类号： C12P13/08
CPC分类号： C12P13/08 , C12N1/20
摘要： A method for producing L-threonine using a microorganism is provided. In the method, additional one or more copies of each of the phosphoenolpyruvate carboxylase (ppc) gene and the threonine operon are integrated into a particular site of the chromosomal DNA of a microorganism, while its inherent ppc gene and threonine operon remain. Accordingly, two or more ppc genes and threonine operons are included in the chromosomal DNA of the microorganism to thereby enhance the expression of the ppc gene encoding an enzyme to convert phosphoenolpyruvate to a threonine biosynthesis precursor, oxaloacetete, and the genes encoding enzymes involved in the synthetic pathway of threonine from oxaloacetate, including thrA (aspartokinaseI-homoserine dehydrogenase), thrB (homoserine kinase), and thrC (threonine synthase), thereby markedly increasing L-threonine productivity.
摘要翻译：提供了使用微生物生产L-苏氨酸的方法。在该方法中，每个磷酸烯醇丙酮酸羧化酶（ppc）基因和苏氨酸操纵子的另外一个或多个拷贝整合到微生物的染色体DNA的特定位点，而其固有的ppc基因和苏氨酸操纵子保留。因此，在微生物的染色体DNA中包含两个以上的ppc基因和苏氨酸操纵子，从而增强编码酶的ppc基因的表达，以将磷酸烯醇丙酮酸转化为苏氨酸生物合成前体，oxaloacetete，以及编码参与包括thrA（天冬氨酸激酶 - 高丝氨酸脱氢酶），thrB（高丝氨酸激酶）和thrC（苏氨酸合成酶）的苏氨酸的合成途径，从而显着提高了L-苏氨酸生产力。

7. 发明申请

WO2011010870A3 GENETIC MARKER FOR PREDICTING THE SURVIVAL OF A PATIENT WITH EARLY-STAGE LUNG CANCER, AND METHOD FOR PREDICTING SURVIVAL USING SAME 审中-公开
标题翻译：用于预测患有早期肺癌患者的遗传标记和使用其预测存活的方法
公开(公告)号：WO2011010870A3
公开(公告)日：2011-06-30
申请号：PCT/KR2010004779
申请日：2010-07-21
申请人： LEE MYUNG-HOON , PARK JAE YONG , KIM IN SAN
发明人： LEE MYUNG-HOON , PARK JAE YONG , KIM IN SAN
IPC分类号： C12Q1/68 , C12N15/12 , G01N33/574
CPC分类号： C12N9/6475 , C12Q1/6886 , C12Q2600/118 , C12Q2600/156
摘要： The present invention relates to a marker for predicting the risk of lung cancer and predicting a prognosis for the survival of a patient with lung cancer using the polymorphism of the CASP7 and/or CASP9 gene(s), and to a method for predicting the risk of lung cancer and predicting a prognosis for survival of a lung cancer patient using the marker. More particularly, the present invention relates to a composition for predicting the risk of lung cancer and predicting a prognosis for the survival of a patient with lung cancer on the basis of the polymorphism of the CASP7 and/or CASP9 gene(s), to a kit for predicting the risk of lung cancer and predicting a prognosis for the survival of a lung cancer patient using the composition, to a microarray, and to a method for predicting the risk of lung cancer and predicting a prognosis for the survival of a lung cancer patient.
摘要翻译：本发明涉及使用CASP7和/或CASP9基因的多态性预测肺癌风险和预测患有肺癌患者的预后的标志物，以及预测风险的方法的肺癌，并使用标记预测肺癌患者的存活预后。更具体地，本发明涉及用于预测肺癌风险的组合物，并且基于CASP7和/或CASP9基因的多态性预测患有肺癌患者的存活的预后，用于预测肺癌的风险并预测使用该组合物的肺癌患者的生存预测的试剂盒，微阵列，以及用于预测肺癌风险和预测肺癌存活预后的方法患者。

8. 发明申请

WO2009096616A1 COMPOSITION FOR INHIBITING THE ACTIVITY OF INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR SUBTYPE III 审中-公开
标题翻译：用于抑制INOSITOL 1,4,5-三磷酸酯受体亚型III活性的组合物
公开(公告)号：WO2009096616A1
公开(公告)日：2009-08-06
申请号：PCT/KR2008/000603
申请日：2008-01-31
申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , LEE, Changjoon Justin , KANG, Sang-Soo , HAN, Kyung-Suk , ROH, Eun-Joo , PARK, Jae-Yong
发明人： LEE, Changjoon Justin , KANG, Sang-Soo , HAN, Kyung-Suk , ROH, Eun-Joo , PARK, Jae-Yong
IPC分类号： A61K31/522
CPC分类号： A61K31/522
摘要： An agent for inhibiting the activity of inositol-1,4,5-triphospate receptor subtype 3 (IP 3 R3), containing caffeine and/or its analogs, and/or their pharmaceutically acceptable salts, as an active ingredient, is provided. A composition for preventing and/or treating a disease associated with Ca 2+ release through IP 3 R3, containing the IP 3 R3 inhibiting agent, is also provided.
摘要翻译：提供了用于抑制含有咖啡因和/或其类似物的肌醇-1,4,5-三磷酸受体亚型3（IP3R3）和/或其药学上可接受的盐作为活性成分的活性的药剂。还提供了用于预防和/或治疗与包含IP3R3抑制剂的IP3R3释放相关的疾病的组合物。

9. 发明申请

WO2008130164A8 A BLUETOOTH DEVICE HAVING A MEMORY AND METHOD THEREFOR 审中-公开
公开(公告)号：WO2008130164A8
公开(公告)日：2008-10-30
申请号：PCT/KR2008/002223
申请日：2008-04-18
申请人： PARK, Jae Yong
发明人： PARK, Jae Yong
IPC分类号： H04B1/40 , H04B7/24
摘要： The present invention relates to a broadcast receiver, and more particularly, to a method for au tomatically extracting specific sections of a moving picture which a user wishes to record and for editing the extracted sections and a broadcast receiver adopting the same. [MAIN DRAWING] FIG. 2 [INDEX WORDS] Bluetooth, mobile communication terminal, Bluetooth headset, memory, application.

10. 发明申请

WO2003080843A1 METHOD FOR L-THREONINE PRODUCTION 审中-公开
标题翻译： L-螺旋藻生产方法
公开(公告)号：WO2003080843A1
公开(公告)日：2003-10-02
申请号：PCT/KR2002/000920
申请日：2002-05-16
申请人： CHEIL JEDANG CORPORATION , PARK, Jae-yong , LEE, Byoung-choon , KIM, Dae-cheol , LEE, Jin-ho , CHO, Jae-yong , PARK, Young-hoon
发明人： PARK, Jae-yong , LEE, Byoung-choon , KIM, Dae-cheol , LEE, Jin-ho , CHO, Jae-yong , PARK, Young-hoon
IPC分类号： C12N15/70
CPC分类号： C12N9/88 , C12P13/08
摘要： A method for producing L-threonine using a microorganism is provided. In the method, the threonine dehydratase (tdc) gene existing in the genomic DNA of the microorganism is partially deactivated using a recombination technique. For a microorganism strain with enhanced activity of threonine operon-containing enzymes and the phosphoenolpyruvate carboxylase (ppc) gene, the tdc gene engaged in one of the four threonine metabolic pathways is specifically deactivated, thereby markedly increasing the yield of L-threonine.
摘要翻译：提供了使用微生物生产L-苏氨酸的方法。在该方法中，存在于微生物的基因组DNA中的苏氨酸脱水酶（tdc）基因使用重组技术部分失活。对于具有增强的苏氨酸操纵子酶和磷酸烯醇丙酮酸羧化酶（ppc）基因的活性的微生物菌株，特异性地失活了四种苏氨酸代谢途径之一的tdc基因，从而显着提高L-苏氨酸的产量。

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