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1. 发明申请

WO2010002888A3 ANGIOPLASTY AND TISSUE ABLATION APPARATUS AND METHOD 审中-公开
公开(公告)号：WO2010002888A3
公开(公告)日：2010-01-07
申请号：PCT/US2009/049251
申请日：2009-06-30
申请人： MEDWAVES, INC. , ORMSBY, Theodore, C. , LEUNG, George , SHEN, Gwo, Jenn
发明人： ORMSBY, Theodore, C. , LEUNG, George , SHEN, Gwo, Jenn
IPC分类号： A61B18/18 , A61M25/10
摘要： A coaxial cable apparatus which transmits radio frequency (RF) energy for the ablation of biological tissues has inner and outer coaxial conductors extending substantially the entire length of the cable from a proximal end portion to a distal end portion. An RF antenna is disposed at the distal end portion of the cable and transmits RF energy for ablation of a tissue region to be treated. An angioplasty balloon is disposed over the RF antenna and communicates with a fluid supply and extraction passageway extending through the cable to allow the balloon to be inflated for an angioplasty procedure including tissue ablation, and to be deflated after the procedure is complete.

2. 发明申请

WO2008005668A3 RADIO-FREQUENCY BASED CATHETER SYSTEM AND METHOD FOR ABLATING BIOLOGICAL TISSUES 审中-公开
标题翻译：基于无线电频率的导管系统及其生物组织研究方法
公开(公告)号：WO2008005668A3
公开(公告)日：2008-10-30
申请号：PCT/US2007071121
申请日：2007-06-13
申请人： MEDWAVES INC , ORMSBY THEODORE C , LEUNG GEORGE L , SHEN GWO JENN , CHU PETER , LAW MING-FAN
发明人： ORMSBY THEODORE C , LEUNG GEORGE L , SHEN GWO JENN , CHU PETER , LAW MING-FAN
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2017/00256 , A61B2017/003 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00779 , A61B2018/00785 , A61B2018/00791 , A61B2018/00946
摘要： A radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency ("RF") generator (616) for selectively generating a high frequency RF energy signal in a deployable catheter (500) having an RF transmission line, an RF antenna (250) mounted on the distal portion of the catheter, and a temperature sensor (520) also mounted on a distal portion of the catheter for detecting temperature adjacent an ablation site. A control system (610) adjusts the RF energy signal so that the detected temperature is at or close to a selected temperature setting or within a selected temperature range.
摘要翻译：用于消除患者体内血液中的生物组织的基于射频的导管系统和方法包括用于在可展开的导管（500）中选择性地产生高频RF能量信号的射频（“RF”）发生器（616）具有RF传输线，安装在导管的远端部分上的RF天线（250）和还安装在导管的远端部分上的温度传感器（520），用于检测消融部位附近的温度。控制系统（610）调节RF能量信号，使得检测到的温度处于或接近所选择的温度设置或者在选定的温度范围内。

3. 发明申请

WO2009039093A3 A RADIO FREQUENCY ENERGY TRANSMISSION DEVICE FOR THE ABLATION OF BIOLOGICAL TISSUES 审中-公开
标题翻译：一种用于清除生物组织的射频能量传输装置
公开(公告)号：WO2009039093A3
公开(公告)日：2009-05-14
申请号：PCT/US2008076523
申请日：2008-09-16
申请人： MEDWAVES INC , ORMSBY THEODORE C , LEUNG GEORGE L , LAW MING FAN
发明人： ORMSBY THEODORE C , LEUNG GEORGE L , LAW MING FAN
IPC分类号： A61B18/18
CPC分类号： A61B18/14 , A61B18/18 , A61B18/1815 , A61B2017/00243 , A61B2018/00577 , H01Q11/08
摘要： A radio frequency energy transmission device comprises a hollow coaxial electrically conductive cable which conducts radio frequency (RF) energy, particularly microwave energy, for the ablation of biological tissue. Coaxial inner and outer conductors extend substantially the entire length of the cable from the proximal end to a distal end portion of the cable. The inner conductor comprises a tubular member having a hollow, axially extending lumen, and the outer conductor comprises a tubular member disposed in a substantially coaxial relationship over at least a portion of the inner conductor. Dielectricity to impede conduction between the inner and outer conductors is introduced with a vacuum or dielectric medium disposed between the inner and outer conductors. An ablating member, which delivers radio frequency energy to body tissue is disposed at a distal end portion of the cable. The ablating member can be a helical coil, a monopole or a microstrip circuit.
摘要翻译：射频能量传输装置包括传导射频（RF）能量，特别是微波能量的中空同轴导电电缆，用于消融生物组织。同轴内导体和外导体基本上从电缆的近端延伸到电缆的远端部分的整个长度。内导体包括具有中空的轴向延伸内腔的管状构件，并且外导体包括管状构件，该管状构件在内导体的至少一部分上以基本上同轴的关系设置。用于阻止内导体和外导体之间的导电的电介质被引入设置在内导体和外导体之间的真空或电介质。将射频能量递送至身体组织的消融构件布置在电缆的远端部分处。消融元件可以是螺旋线圈，单极或微带电路。

4. 发明申请

WO2005016119A2 RADIO-FREQUENCY BASED CATHETER SYSTEM AND METHOD FOR ABLATING BIOLOGICAL TISSUES 审中-公开
标题翻译：基于无线电频率的导管系统及其生物组织研究方法
公开(公告)号：WO2005016119A2
公开(公告)日：2005-02-24
申请号：PCT/US2004/024696
申请日：2004-07-30
申请人： MEDWAVES, INC. , ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
发明人： ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61B
CPC分类号： A61B18/1492 , A61B18/18 , A61B90/39 , A61B2017/003 , A61B2018/00214 , A61B2018/00839 , A61B2018/00875 , A61B2018/1407 , A61B2018/1437
摘要： An improved radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency ("RF") generator for selectively generating high frequency energy in a deployable catheter having a RF co-axial transmission line with a hollow lumen, a RF antenna mounted on the distal portion of the catheter, and steering control lines in the lumen of the transmission line for steering catheter while being inserted into the body vessel and for deflecting the RF antenna to accommodate the contour of the body vessel where tissue ablation is needed. The RF generator having variable output frequency is adapted to generate and communicate RF energy to the RF antenna that minimizes reflected energy from the antenna-tissue interface. In application, the RF antenna establishes line of contact with the body vessel conformable to its internal contour to prescribe the precise tissue ablation pathway despite body vessel movements. The RF antenna is steered by the steering control lines to establish its body vessel conformation. The catheter system is energized and system senses the reflected RF power relative to its output power and adjusts the frequency of the power output to effect impedance match between the transmission line of the system and the tissue ablation load.
摘要翻译：改进的基于射频的导管系统和用于消除患者体内血液中生物组织的方法包括：射频（“RF”）发生器，用于在具有RF同轴传输线的可展开导管中选择性地产生高频能量具有中空管腔，安装在导管的远端部分上的RF天线以及用于转向导管的传输线的内腔中的转向控制线，同时插入到身体容器中并用于偏转RF天线以适应需要组织消融的身体血管。具有可变输出频率的RF发生器适于产生RF通信并将RF能量传送到RF天线，其使得天线 - 组织界面的反射能量最小化。在应用中，RF天线与体内血管建立接触线，以符合其内部轮廓，以规定精确的组织消融路径，尽管身体血管运动。 RF天线由转向控制线转向以建立其身体血管构象。导管系统被通电，系统相对于其输出功率感测反射的RF功率，并且调节功率输出的频率以实现系统的传输线与组织消融负载之间的阻抗匹配。

5. 发明申请

WO2008051708A2 ABLATION CATHETER APPARATUS WITH ONE OR MORE ELECTRODES 审中-公开
标题翻译：具有一个或多个电极的消融导管设备
公开(公告)号：WO2008051708A2
公开(公告)日：2008-05-02
申请号：PCT/US2007/080819
申请日：2007-10-09
申请人： MEDWAVES, INC. , ORMSBY, Theodore C. , LEUNG, George L. , SHEN, Gwo Jenn , CHU, Peter
发明人： ORMSBY, Theodore C. , LEUNG, George L. , SHEN, Gwo Jenn , CHU, Peter
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2017/003 , A61B2018/00839 , A61B2018/00916 , A61B2018/00946 , A61B2018/183
摘要： A radio frequency (RF) ablation catheter has a flexible distal end portion so that it can be deflected to position an antenna disposed in the distal end portion adjacent a tissue site to be treated. At least one electrical conductor is coupled to the antenna and extends through the catheter to the proximal end of the catheter to a connector at the proximal end of the catheter for connection to a power supply for the RF antenna. At least one electrode is disposed at the distal end portion of the catheter and electrically coupled to the proximal end connector for connection to a monitor. The electrode is of a flexible, electrically conductive material such as conductive polymer material. The electrode may be an electrocardiogram (ECG) electrode.
摘要翻译：射频（RF）消融导管具有柔性远端部分，使得其可偏转以将设置在远端部分中的天线定位在待治疗的组织部位附近。至少一个电导体联接到天线并且穿过导管延伸到导管的近端到位于导管近端的连接器，用于连接到RF天线的电源。至少一个电极设置在导管的远端部分处并电耦合到近端连接器以连接到监视器。电极是柔性的导电材料，例如导电聚合物材料。电极可以是心电图（ECG）电极。

6. 发明申请

WO2004050171A3 DEVICES AND METHODS FOR SELECTIVE ORIENTATION OF ELECTROSURGICAL DEVICES 审中-公开
标题翻译：用于选择性定向的静电装置的装置和方法
公开(公告)号：WO2004050171A3
公开(公告)日：2005-04-14
申请号：PCT/US0338782
申请日：2003-12-03
申请人： ARTHROCARE CORP , DAVISON TERRY S , YATES MATTHEW L , ORMSBY THEODORE C , WOLOSZKO JEAN
发明人： DAVISON TERRY S , YATES MATTHEW L , ORMSBY THEODORE C , WOLOSZKO JEAN
IPC分类号： A61B18/14 , A61B18/18 , A61N20060101
CPC分类号： A61B18/1482 , A61B2017/003
摘要： Devices and methods for the selective orientation of electrodes for effecting the controlled ablation, coagulation, or other modification of a target tissue in vivo with no or minimal collateral tissue damage. The subject devices are electrosurgical wands configured to only bend in a single plane. The subject methods involve use of the subject devices to prepare for the treatment of a target tissue site.
摘要翻译：用于选择性取向电极的装置和方法，用于在没有或最小侧支组织损伤的情况下对体内靶组织进行受控消融，凝固或其它修饰。主体装置是构造成仅在单个平面中弯曲的电外科手杖。本发明方法涉及使用受试装置来准备治疗靶组织部位。

7. 发明申请

WO2004073766A2 PREFORMED CATHETER SET FOR USE WITH A LINEAR ABLATION SYSTEM TO PRODUCE ABLATION LINES IN THE LEFT AND RIGHT ATRIUM FOR TREATMENT OF ATRIAL FIBRILLATION 审中-公开
标题翻译：用于线性牵引系统的预制导管装置，用于在左心室和右心室内产生用于治疗椎间盘突出的消融线
公开(公告)号：WO2004073766A2
公开(公告)日：2004-09-02
申请号：PCT/US2004/004693
申请日：2004-02-19
申请人： MEDWAVES INC. , FELD, Gregory, K. , ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
发明人： FELD, Gregory, K. , ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61M
CPC分类号： A61B18/1492 , A61B2018/183
摘要： A preformed catheter set for production of linear ablation lines in the left and right atrium for treatment of atrial fibrillation includes at least a first catheter including a pre-shaped distal segment having a distal linear ablation antenna and a U-shaped curve portion proximal to the distal linear ablation antenna.
摘要翻译：用于在左心房和右心房中产生线性消融线的预成型导管套件用于治疗房颤包括至少第一导管，其包括具有远端线性消融天线的预形远端区段和靠近该房间的U形曲线部分远端线性消融天线。

8. 发明申请

WO2004050171A2 DEVICES AND METHODS FOR SELECTIVE ORIENTATION OF ELECTROSURGICAL DEVICES 审中-公开
标题翻译：用于选择性定向的静电装置的装置和方法
公开(公告)号：WO2004050171A2
公开(公告)日：2004-06-17
申请号：PCT/US2003/038782
申请日：2003-12-03
申请人： ARTHROCARE CORPORATION , DAVISON, Terry, S. , YATES, Matthew, L. , ORMSBY, Theodore, C. , WOLOSZKO, Jean
发明人： DAVISON, Terry, S. , YATES, Matthew, L. , ORMSBY, Theodore, C. , WOLOSZKO, Jean
IPC分类号： A61N
CPC分类号： A61B18/1482 , A61B2017/003
摘要： Devices and methods for the selective orientation of electrodes for effecting the controlled ablation, coagulation, or other modification of a target tissue in vivo with no or minimal collateral tissue damage. The subject devices are electrosurgical wands configured to only bend in a single plane. The subject methods involve use of the subject devices to prepare for the treatment of a target tissue site.
摘要翻译：用于选择性取向电极的装置和方法，用于在没有或最小侧支组织损伤的情况下对体内靶组织进行受控消融，凝固或其它修饰。主体装置是构造成仅在单个平面中弯曲的电外科手杖。本发明方法涉及使用受试装置来准备治疗靶组织部位。

9. 发明申请

WO2011066445A3 RADIO FREQUENCY ABLATION SYSTEM WITH TRACKING SENSOR 审中-公开
标题翻译：带跟踪传感器的射频消融系统
公开(公告)号：WO2011066445A3
公开(公告)日：2011-10-06
申请号：PCT/US2010058082
申请日：2010-11-24
申请人： MEDWAVES INC , ORMSBY THEODORE C , JENN SHEN GWO , LEUNG GEORGE L
发明人： ORMSBY THEODORE C , JENN SHEN GWO , LEUNG GEORGE L
IPC分类号： A61B18/18 , A61B18/12 , A61B18/14
CPC分类号： A61B18/1815 , A61B2018/00196 , A61B2018/1853 , A61B2018/1861 , A61B2034/2051
摘要： An RF ablation system has a hollow conductive coaxial cable comprising inner and outer coaxial tubular conductors, and an ablating member mounted at the distal end portion of the cable for delivery of radio frequency energy including microwaves to the target body tissue. The inner conductor has a central lumen and extends at least up to the ablating member. At least one electromagnetic tracking sensor coil with a magnetic core is located in the central lumen at the distal end portion of the cable, close to the distal tip of the cable, and connected to a signal processing unit. An electromagnetic field generator positioned in the vicinity of a patient undergoing treatment generates an electromagnetic field which induces a voltage in the sensor coil. The signal processing unit uses the induced voltage to calculate the position and orientation of the distal end portion or tip of the catheter in a patient's body.
摘要翻译： RF消融系统具有中空导电同轴电缆，其包括内部和外部同轴管状导体以及安装在电缆的远端部分处的消融构件，用于将包括微波的射频能量递送至目标身体组织。内导体具有中心内腔并且至少延伸到消融构件。具有磁芯的至少一个电磁跟踪传感器线圈位于电缆的远端部分处的中央管腔中，靠近电缆的远端，并连接到信号处理单元。位于正在进行治疗的患者附近的电磁场发生器产生电磁场，其在传感器线圈中感应出电压。信号处理单元使用感应电压来计算导管的远端部分或尖端在患者体内的位置和取向。

10. 发明申请

WO2010002888A2 ANGIOPLASTY AND TISSUE ABLATION APPARATUS AND METHOD 审中-公开
标题翻译： ANGIOPLASTY和组织吸收装置和方法
公开(公告)号：WO2010002888A2
公开(公告)日：2010-01-07
申请号：PCT/US2009049251
申请日：2009-06-30
申请人： MEDWAVES INC , ORMSBY THEODORE C , LEUNG GEORGE , SHEN GWO JENN
发明人： ORMSBY THEODORE C , LEUNG GEORGE , SHEN GWO JENN
IPC分类号： A61B18/18 , A61M25/10
CPC分类号： A61F2/958 , A61B18/1492 , A61B18/1815 , A61B2018/00214 , A61B2018/0022 , A61B2018/00422 , A61B2018/1846 , A61B2018/1853 , A61B2018/1861
摘要： A coaxial cable apparatus which transmits radio frequency (RF) energy for the ablation of biological tissues has inner and outer coaxial conductors extending substantially the entire length of the cable from a proximal end portion to a distal end portion. An RF antenna is disposed at the distal end portion of the cable and transmits RF energy for ablation of a tissue region to be treated. An angioplasty balloon is disposed over the RF antenna and communicates with a fluid supply and extraction passageway extending through the cable to allow the balloon to be inflated for an angioplasty procedure including tissue ablation, and to be deflated after the procedure is complete.
摘要翻译：传输用于生物组织消融的射频（RF）能量的同轴电缆装置具有从近端部分到远端部分的大致整个长度的电缆的内部和外部同轴导线。 RF天线设置在电缆的远端部分，并且传输RF能量以消除待治疗的组织区域。血管成形术球囊设置在RF天线上方，并与延伸穿过电缆的流体供应和提取通道连通，以允许气囊膨胀用于包括组织消融的血管成形术程序，并且在手术完成后被放气。

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