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2. 发明申请

WO2003024214A1 ORGAN PRESERVATION APPARATUS AND METHODS 审中-公开
标题翻译：有机保存装置及方法
公开(公告)号：WO2003024214A1
公开(公告)日：2003-03-27
申请号：PCT/US2002/028970
申请日：2002-09-12
申请人： ORGAN TRANSPORT SYSTEMS, INC.
发明人： ALFORD, Marlin L., , DOWBEN, Robert M.,
IPC分类号： A01N1/02
CPC分类号： A01N1/0247 , A01N1/02 , A01N1/0273
摘要： This invention is a transportable organ preservation system which substantially increases the time during which the organ can be maintained viable for successful implantation into a human recipient. A chilled oxygenated nutrient solution is pumped through the vascular bed of the organ after excision of the organ from the donor and during transport. The device of the present invention uses flexible permeable tubing to oxygenate the perfusion fluid while the CO 2 produced by the organ diffuses out of the perfusion fluid. One pressurized two liter "C" cylinder (17) that contains 255 liters of oxygen at standard temperature and pressure can supply oxygen for up to 34 hours of perfusion time. The device uses a simple electric pump (24) driven by a storage battery to circulate the perfusion fluid through the organ being transported. The vessel (8) containing the organ to be transported is held at 4 °C by coolant blocks (6).
摘要翻译：本发明是一种可运输的器官保存系统，其大大增加了器官可以维持生存以便成功植入人类接受者的时间。将冷冻的含氧营养液从供体切除并在运输过程中抽出器官的血管床。本发明的装置使用柔性可渗透管来对灌注流体进行氧化，同时由器官产生的CO 2从灌注液中扩散出来。在标准温度和压力下包含255升氧气的一个加压的两升“C”气瓶（17）可以供给氧气长达34小时的灌注时间。该装置使用由蓄电池驱动的简单电动泵（24），以使灌注流体循环通过被运送的器官。含有待运输器官的容器（8）由冷却剂块（6）保持在4℃。

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