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1. 发明申请

WO2005115599A1 DEVICE FOR GENERATING MICROSPHERES FROM A FLUID, METHOD OF INJECTING AT LEAST ONE FIRST FLUID INTO A SECOND FLUID, AND AN INJECTION PLATE 审中-公开
标题翻译：用于从流体产生微生物的装置，将至少一个第一流体注入第二流体的方法和注射板
公开(公告)号：WO2005115599A1
公开(公告)日：2005-12-08
申请号：PCT/NL2005/000385
申请日：2005-05-25
申请人： NANOMI B.V. , WISSINK, Jeroen Mathijn , VAN RIJN, Cornelis Johannes Maria , NIJDAM, Wietze , GOETING, Christiaan, Haldir , HESKAMP, Iwan Rutger , VELDHUIS, Gerrit Jan
发明人： WISSINK, Jeroen Mathijn , VAN RIJN, Cornelis Johannes Maria , NIJDAM, Wietze , GOETING, Christiaan, Haldir , HESKAMP, Iwan Rutger , VELDHUIS, Gerrit Jan
IPC分类号： B01F3/08
CPC分类号： B01F3/0807 , B01F5/0475 , B01F5/0476 , B01F5/0485 , B01F13/0059 , B01F2215/0427 , B01F2215/0431 , Y10T137/0357 , Y10T137/212
摘要： A device for generating micro spheres from a fluid (13) comprises an injection plate (6) which comprises at least one defined injection channel (1) having on an inlet side an inflow opening for receiving the fluid and on an outlet side an outflow opening for delivering micro spheres (12) formed from the fluid. The device is provided with feed means for carrying the fluid through the injection channel and is in open communication, on a side wall thereof, with at least one secondary channel (10) at least at the position of a break-up point where at least during operation a flow of the fluid in the injection channel breaks up into separate parts. The secondary channel is intended and adapted to comprise an auxiliary fluid at least during operation and at least at the position of a break-up point. For at least a part of the first fluid an inflow resistance of the secondary channel is greater than an inflow resistance of the injection channel. Such a device is employed in a method for injecting a first fluid into a second fluid and a cross-flow of a second fluid is guided over an outlet side of the injection plate.
摘要翻译：用于从流体（13）产生微球的装置包括注射板（6），其包括至少一个限定的注入通道（1），所述注入通道在入口侧具有用于接收流体的流入开口，在出口侧具有流出开口用于递送由流体形成的微球体（12）。该装置设置有用于通过注入通道运送流体的进料装置，并且在其侧壁上与至少一个次要通道（10）开放连通，至少在分解点的位置至少在操作期间，注入通道中的流体流分解成单独的部分。次级通道旨在并适于至少在操作期间和至少在分解点的位置处包括辅助流体。对于第一流体的至少一部分，次通道的流入阻力大于注入通道的流入阻力。这种装置用于将第一流体注入第二流体的方法，并且第二流体的横流被引导到注射板的出口侧。

2. 发明申请

WO2009002178A2 ATOMISING DEVICE, ATOMISING BODY AND METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：原型装置，原型装置及其制造方法
公开(公告)号：WO2009002178A2
公开(公告)日：2008-12-31
申请号：PCT/NL2008/050438
申请日：2008-06-30
申请人： MEDSPRAY XMEMS B.V. , WISSINK, Jeroen Mathijn , HESKAMP, Iwan Rutger , DE KRUIJF, Wilhelmus Petrus Johannes , NIJDAM, Wietze , VAN RIJN, Cornelis Johannes Maria
发明人： WISSINK, Jeroen Mathijn , HESKAMP, Iwan Rutger , DE KRUIJF, Wilhelmus Petrus Johannes , NIJDAM, Wietze , VAN RIJN, Cornelis Johannes Maria
IPC分类号： B05B1/08 , B05B1/26 , B29C65/14
CPC分类号： B05B1/08 , B05B1/26
摘要： An atomizing device, comprising an atomizing body (1 ) with an inlet (16) for receiving a fluid under increased pressure, and with at least one set of outflow ports (18) for allowing the fluid to escape on a delivery side with forming of a vapour. Imaginary central axes of the outflow ports directed in a flow direction herein enclose a mutual angle (α) in order to intersect each other at an intersection (S). The atomizing body comprises a roof (21) and a bottom (11) which extend over at least a first distance (dl) beyond the set of outflow ports (18) and bound a vaporizing space (17) on either side. The intersection (S) of the imaginary central axes of the outflow ports lies at a second distance (d2) from the set of outflow ports, wherein the second distance (d2) is greater than the first distance (dl) and extends beyond the vaporizing space (17). In a further aspect of the invention the atomizing body is able and adapted to capture supplied radiation, thus forming heat. In a further aspect the atomizing body is in an envelope which at least on a boundary layer is adhered with a boundary layer to the atomizing body.
摘要翻译：一种雾化装置，包括具有用于在增加的压力下接收流体的入口（16）的雾化体（1）和至少一组用于允许流体在输送侧逸出的至少一组流出端口（18），形成蒸气沿流动方向引导的流出口的虚拟中心轴在这里封闭相互的角度（a），以在交叉点（S）彼此相交。雾化体包括在至少第一距离（d1）上延伸超出该组流出端口（18）并且限定任一侧上的汽化空间（17）的屋顶（21）和底部（11）。流出端口的假想中心轴线的交点（S）位于距离该组流出端口的第二距离（d2）处，其中第二距离（d2）大于第一距离（d1）并且延伸超出蒸发空间（17）。在本发明的另一方面，雾化体能够并适于捕获供应的辐射，从而形成热量。在另一方面，雾化体是在至少在边界层上附着有边界层至雾化体的外壳。

3. 发明申请

WO2005105276A3 DEVICE WITH A MEMBRANE ON A CARRIER, AS WELL AS A METHOD FOR MANUFACTURING SUCH A MEMBRANE 审中-公开
标题翻译：作为制造这种膜的方法，在载体上具有膜的装置
公开(公告)号：WO2005105276A3
公开(公告)日：2005-12-22
申请号：PCT/NL2005000331
申请日：2005-04-29
申请人： FRIESLAND BRANDS BV , JONGSMA TJEERD , BOS ROELOF , NIJDAM WIETZE , VAN RIJN CORNELIS JOHANNES MAR
发明人： JONGSMA TJEERD , BOS ROELOF , NIJDAM WIETZE , VAN RIJN CORNELIS JOHANNES MAR
IPC分类号： B01D65/10 , B01D67/00 , B01D69/02 , B01D69/10 , B01D71/02
CPC分类号： B01D65/102 , B01D67/0034 , B01D67/0037 , B01D67/0062 , B01D69/02 , B01D69/10 , B01D71/02 , B01D2325/08 , B01D2325/24 , B01D2325/26 , B01D2325/36 , Y10T428/13 , Y10T428/24099 , Y10T428/24182 , Y10T428/24496 , Y10T428/24942 , Y10T428/249954 , Y10T428/249961 , Y10T428/249969 , Y10T428/249981
摘要： The invention relates to a membrane on a carrier for filtration of liquids, comprising a carrier and a membrane. The invention also relates to a method for manufacturing a membrane on a carrier according to the invention. The invention further relates to application of a membrane on a carrier according to the invention as well as to a module comprising such a membrane. The invention also relates to a method for determining fracture in such a membrane on a carrier.
摘要翻译：本发明涉及用于过滤液体的载体上的膜，包括载体和膜。本发明还涉及根据本发明的用于在载体上制造膜的方法。本发明还涉及在根据本发明的载体上的膜的应用以及包含这种膜的模块。本发明还涉及一种用于确定载体上这种膜的断裂的方法。

4. 发明申请

WO0243937A3 METHOD OF MAKING A PRODUCT WITH A MICRO OR NANO SIZED STRUCTURE AND PRODUCT 审中-公开
标题翻译：制造具有微米或纳米尺寸结构和产品的产品的方法
公开(公告)号：WO0243937A3
公开(公告)日：2002-10-03
申请号：PCT/NL0100874
申请日：2001-12-03
申请人： AQUAMARIJN HOLDING B V , VAN RIJN CORNELIS JOHANNES MAR , VOGELAAR LAURA , NIJDAM WIETZE , BARSEMA JONATHAN NATHANIEL , WESSLING MATTHIAS
发明人： VAN RIJN CORNELIS JOHANNES MAR , VOGELAAR LAURA , NIJDAM WIETZE , BARSEMA JONATHAN NATHANIEL , WESSLING MATTHIAS
IPC分类号： A61F2/04 , A61F2/06 , A61L27/50 , A61L27/56 , B01D67/00 , B01D69/00 , B01D69/08 , B01D69/12 , B01D71/02 , B01D71/64 , B01D71/68 , B01J19/00 , B01L3/00 , B01L3/02 , B29C33/00 , B29C41/08 , B29C41/38 , B29C67/02 , B81B1/00 , B81C1/00 , G01N27/447 , B01D29/01 , B01D69/06
CPC分类号： B01D67/0088 , A61F2/06 , A61F2002/044 , A61F2002/046 , A61L27/50 , A61L27/56 , B01D67/0009 , B01D67/0018 , B01D67/002 , B01D67/0069 , B01D67/0072 , B01D67/0093 , B01D69/00 , B01D69/02 , B01D69/08 , B01D69/12 , B01D71/02 , B01D71/64 , B01D71/68 , B01D2323/06 , B01D2323/08 , B01D2323/30 , B01D2325/022 , B01D2325/04 , B01J19/0093 , B01J2219/00783 , B01J2219/00824 , B01J2219/00833 , B01J2219/00835 , B01J2219/00844 , B01J2219/0086 , B01J2219/00864 , B01J2219/00907 , B01L3/0241 , B01L3/5085 , B01L2200/12 , B01L2300/0819 , B29C33/0033 , B29C41/08 , B29C41/38 , B29C67/02 , B29K2105/0073 , B29L2031/737 , B81B2201/10 , B81C99/008 , B81C2201/0115 , B81C2201/034 , G01N27/44704 , H01L31/18 , Y10T428/24
摘要： Using phase separation technique perforated as well as non-perforated polymeric structures can be made with high aspect ratios (>5). By varying the phase separation process the properties (e.g. porous, non-porous, dense, open skin) of the moulded product can be tuned. Applications are described in the field of micro fluidics (e.g. micro arrays, electrophoretic boards), optics, polymeric solar cells, ball grid arrays, and tissue engineering.
摘要翻译：使用相分离技术穿孔以及非穿孔聚合物结构可以制成高纵横比（> 5）。通过改变相分离方法，可以调节模制产品的性质（例如多孔，无孔，致密，开放的皮肤）。应用在微流体学（例如微阵列，电泳板），光学，聚合物太阳能电池，球栅阵列和组织工程领域中描述。

5. 发明申请

WO2010123347A1 ATOMISING BODY, ATOMISING DEVICE, INHALER, MANUFACTURING METHOD OF MANUFACTURING AN ATOMISING BODY AND ASSEMBLY METHOD FOR ASSEMBLING AN ATOMISING DEVICE 审中-公开
标题翻译：主体，原型装置，吸入器，制造原理体的制造方法和组装装置的组装方法
公开(公告)号：WO2010123347A1
公开(公告)日：2010-10-28
申请号：PCT/NL2010/000070
申请日：2010-04-22
申请人： MEDSPRAY XMEMS B.V. , HESKAMP, Iwan, Rutger , DE KRUIJF, Wilhelmus, Petrus, Johannes , NIJDAM, Wietze , WISSINK, Jeroen, Mathijn
发明人： HESKAMP, Iwan, Rutger , DE KRUIJF, Wilhelmus, Petrus, Johannes , NIJDAM, Wietze , WISSINK, Jeroen, Mathijn
IPC分类号： B05B1/14 , B05B1/18 , A61M11/00 , B01D67/00 , B81C1/00 , B65D83/14
CPC分类号： A61M11/003 , A61M11/007 , A61M11/08 , A61M15/009 , B01D63/081 , B01D63/082 , B01D67/0062 , B05B1/14 , B65D83/14 , Y10T29/49826
摘要： A method of manufacturing an atomising body for an atomising device is described. The method comprises the steps of - providing a support element having a first layer on a first surface of the support element and a second layer on a second surface of the support element, the first layer comprising a first perforated membrane and the second layer comprising a process orifice, - etching a cavity through the support element, the cavity forming a fluid connection from the process orifice to the perforated membrane, by providing etching substance to the process orifice. The atomising body as obtained may advantageously be applied in an atomising device or an inhaler.
摘要翻译：描述了一种制造雾化装置的雾化体的方法。该方法包括以下步骤：提供在支撑元件的第一表面上具有第一层的支撑元件和在支撑元件的第二表面上的第二层，第一层包括第一穿孔膜，第二层包括处理孔口， - 通过支撑元件蚀刻空腔，空腔通过向工艺孔口提供蚀刻物质形成从工艺孔口到穿孔膜的流体连接。获得的雾化体可以有利地应用于雾化装置或吸入器中。

6. 发明申请

WO2009002178A3 ATOMISING DEVICE, ATOMISING BODY AND METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：原型装置，原型装置及其制造方法
公开(公告)号：WO2009002178A3
公开(公告)日：2009-05-14
申请号：PCT/NL2008050438
申请日：2008-06-30
申请人： MEDSPRAY XMEMS BV , WISSINK JEROEN MATHIJN , HESKAMP IWAN RUTGER , DE KRUIJF WILHELMUS PETRUS JOH , NIJDAM WIETZE , VAN RIJN CORNELIS JOHANNES MAR
发明人： WISSINK JEROEN MATHIJN , HESKAMP IWAN RUTGER , DE KRUIJF WILHELMUS PETRUS JOHANNES , NIJDAM WIETZE , VAN RIJN CORNELIS JOHANNES MARIA
IPC分类号： B05B1/08 , B05B1/26 , B29C65/14
CPC分类号： B05B1/08 , B05B1/26
摘要： An atomizing device, comprising an atomizing body (1 ) with an inlet (16) for receiving a fluid under increased pressure, and with at least one set of outflow ports (18) for allowing the fluid to escape on a delivery side with forming of a vapour. Imaginary central axes of the outflow ports directed in a flow direction herein enclose a mutual angle (a) in order to intersect each other at an intersection (S). The atomizing body comprises a roof (21) and a bottom (11) which extend over at least a first distance (dl) beyond the set of outflow ports (18) and bound a vaporizing space (17) on either side. The intersection (S) of the imaginary central axes of the outflow ports lies at a second distance (d2) from the set of outflow ports, wherein the second distance (d2) is greater than the first distance (dl) and extends beyond the vaporizing space (17). In a further aspect of the invention the atomizing body is able and adapted to capture supplied radiation, thus forming heat. In a further aspect the atomizing body is in an envelope which at least on a boundary layer is adhered with a boundary layer to the atomizing body.
摘要翻译：一种雾化装置，包括具有用于在增加的压力下接收流体的入口（16）的雾化体（1）和至少一组用于允许流体在输送侧逸出的至少一组流出端口（18），形成蒸气沿流动方向引导的流出口的虚拟中心轴在这里封闭相互的角度（a），以在交叉点（S）彼此相交。雾化体包括在至少第一距离（d1）上延伸超出该组流出端口（18）并且限定任一侧上的汽化空间（17）的屋顶（21）和底部（11）。流出端口的假想中心轴线的交点（S）位于距离该组流出端口的第二距离（d2）处，其中第二距离（d2）大于第一距离（d1）并且延伸超出蒸发空间（17）。在本发明的另一方面，雾化体能够并适于捕获供应的辐射，从而形成热量。在另一方面，雾化体是在至少在边界层上附着有边界层至雾化体的外壳。

7. 发明申请

WO2006094796A1 INHALATOR MIT EINEM MISCHKANAL ZUM ERZEUGEN EINES ZU INHALIERENDEN AEROSOLS 审中-公开
标题翻译：具混合渠道产生，吸入浮质INHALER
公开(公告)号：WO2006094796A1
公开(公告)日：2006-09-14
申请号：PCT/EP2006/002154
申请日：2006-03-09
申请人： MEDSPRAY XMEMS BV , WISSINK, Jeroen Mathijn , NIJDAM, Wietze , HESKAMP, Iwan Rutger , PADBERG, Marc, Herman
发明人： WISSINK, Jeroen Mathijn , NIJDAM, Wietze , HESKAMP, Iwan Rutger , PADBERG, Marc, Herman
IPC分类号： A61M11/06 , A61M15/00
CPC分类号： A61M15/009 , A61M11/06 , A61M2206/10
摘要： Inhalator mit einem Mischkanal (1) zum Erzeugen eines Aerosols, wobei der Mischkanal aufweist: eine in den Mund einzuführende Auslaßöffnung (9) und eine Einlaßöffnung (3) zum Einsaugen der Luft und einen zwischen Ein- und Auslaßöffnung (3, 9) liegenden Einspritzbereich (6) .mit einer Düsenöffnung (10) zum Einspritzen eines flüssigen Medikaments in Form eines Strahls aus dispersen Tröpfchen in den Mischkanal. Die Innenseite des Einspritzbereichs fluchtet weitgehend zumindest mit dem ihr einlaßseitig benachbarten Teil des mittleren Oberflächenverlaufs (22) der Innenseite der Kanalwand (11) , wobei ein etwaiger Höhenunterschied (17) zwischen der Innenseite des Einspritzbereichs und dem ihr benachbarten Teil des mittleren Oberflächenverlaufs (22) der Innenseite der Kanalwand weniger als 1 mm oder 100 µm oder 20 µm beträgt.
摘要翻译：吸入器具有用于产生气雾剂的方法，其中所述混合通道的混合通道（1）：一个被引入到所述出口开口的口（9）和（3）用于吸入空气并在入口和出口开口之间的入口开口（3,9）位于喷射区（6）。随着在分散于该混合通道液滴的喷流的形式注入液体药剂的喷嘴开口（10）。注入区的内部被大致对准的至少到通道壁（11），内部的中间面轮廓（22）的入口端相邻的部件，其中所述注入区的内部和中间表面轮廓的相邻部分之间的可能的高度差（17）（22）是通道壁的内部是小于1mm或100微米或20微米。

8. 发明申请

WO2005105276A2 DEVICE WITH A MEMBRANE ON A CARRIER, AS WELL AS A METHOD FOR MANUFACTURING SUCH A MEMBRANE 审中-公开
标题翻译：带有载体膜的装置，以及制造这种膜的方法
公开(公告)号：WO2005105276A2
公开(公告)日：2005-11-10
申请号：PCT/NL2005/000331
申请日：2005-04-29
申请人： FRIESLAND BRANDS B.V. , JONGSMA, Tjeerd , BOS, Roelof , NIJDAM, Wietze , VAN RIJN, Cornelis, Johannes, Maria
发明人： JONGSMA, Tjeerd , BOS, Roelof , NIJDAM, Wietze , VAN RIJN, Cornelis, Johannes, Maria
IPC分类号： B01D69/10
CPC分类号： B01D65/102 , B01D67/0034 , B01D67/0037 , B01D67/0062 , B01D69/02 , B01D69/10 , B01D71/02 , B01D2325/08 , B01D2325/24 , B01D2325/26 , B01D2325/36 , Y10T428/13 , Y10T428/24099 , Y10T428/24182 , Y10T428/24496 , Y10T428/24942 , Y10T428/249954 , Y10T428/249961 , Y10T428/249969 , Y10T428/249981
摘要： The invention relates to a membrane on a carrier for filtration of liquids, comprising a carrier and a membrane. The invention also relates to a method for manufacturing a membrane on a carrier according to the invention. The invention further relates to application of a membrane on a carrier according to the invention as well as to a module comprising such a membrane. The invention also relates to a method for determining fracture in such a membrane on a carrier.
摘要翻译：本发明涉及用于过滤液体的载体上的膜，其包含载体和膜。本发明还涉及用于制造根据本发明的载体上的膜的方法。本发明还涉及根据本发明在载体上应用膜以及包括这种膜的模块。本发明还涉及一种用于确定载体上的这种膜中的断裂的方法。

9. 发明申请

WO1997040213A1 ELECTROFORMING METHOD, ELECTROFORMING MANDREL AND ELECTROFORMED PRODUCT 审中-公开
标题翻译：电镀方法，电镀和电镀产品
公开(公告)号：WO1997040213A1
公开(公告)日：1997-10-30
申请号：PCT/NL1997000203
申请日：1997-04-18
申请人： STORK VECO B.V. , AQUAMARIJN MICRO FILTRATION B.V. , KNOL, Harm, Gerrit , KRUITHOF, Cornelis, Johannes , VAN RIJN, Cornelis, Johannes, Maria , NIJDAM, Wietze
发明人： STORK VECO B.V. , AQUAMARIJN MICRO FILTRATION B.V.
IPC分类号： C25D01/10
CPC分类号： C25D1/10 , C25D1/08
摘要： In an electroforming method for making metal products (10) having a pattern of openings (9) separated by dykes (8) using a mandrel in an electroplating bath, metal from the bath is deposited on at least two electrically mutually insulated regions. Said regions comprise at least one main pattern (3) for product dykes (8) to be formed, which main pattern (3) is electrically insulated from at least one ancillary pattern (5) for a reinforcement (7) to be formed. In the method according to the invention, first the ancillary pattern (5) is connected to a current source in order to form reinforcement (7) thereon and in order to effect an electrical connection between the ancillary pattern (5) and the main pattern (3) by means of the growing metal. During the continuation of the method, reinforcement (7) is thickened and the product dykes (8) are formed. A strong product having different thicknesses is therefore obtained in one step. A mandrel suitable for use in the method is also described.
摘要翻译：在用于在电镀浴中使用心轴制造具有由堤（8）分开的开口（9）图案的金属制品（10）的电铸方法中，来自浴的金属沉积在至少两个电互相绝缘的区域上。所述区域包括用于要形成的产品堤坝（8）的至少一个主图案（3），该主图案（3）与要形成的加强件（7）的至少一个辅助图案（5）电绝缘。在根据本发明的方法中，首先，辅助图案（5）连接到电流源以在其上形成加强件（7），并且为了实现辅助图案（5）和主图案（5）之间的电连接 3）通过生长的金属。在该方法的继续期间，钢筋（7）变厚并形成产品（8）。因此，在一个步骤中获得具有不同厚度的强力产品。还描述了适用于该方法的心轴。

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