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1. 发明申请

WO2014113473A3 WATER SAVING DEVICE 审中-公开
公开(公告)号：WO2014113473A3
公开(公告)日：2014-07-24
申请号：PCT/US2014/011685
申请日：2014-01-15
申请人： MYERS, Kevin, P.
发明人： MYERS, Kevin, P.
IPC分类号： G01F1/00 , G01F3/00 , G01P5/00
摘要： A water saving device including a housing and a processor disposed within the housing. The processor calculates a water volume expended over a period of time based on a predetermined volumetric flow rate and time. A sensor is disposed within the housing for sensing the presence of a user. The sensor is operably connected to the processor. The sensor generates a signal to cause the processor to begin calculating the water volume upon sensing the presence of a user. A display indicates the expended water volume and is operatively connected to the processor. The display shows a virtual water level which rises as time and water usage increases.

2. 发明申请

WO2010059572A1 MIXER IMPELLER 审中-公开
标题翻译：搅拌机
公开(公告)号：WO2010059572A1
公开(公告)日：2010-05-27
申请号：PCT/US2009/064662
申请日：2009-11-17
申请人： CHEMINEER, INC. , JANZ, Eric, Edward, Antonio , MYERS, Kevin, J. , FRYERS, William , FASANO, Julian, B.
发明人： JANZ, Eric, Edward, Antonio , MYERS, Kevin, J. , FRYERS, William , FASANO, Julian, B.
IPC分类号： B01F7/00 , B01F3/08 , B01F3/12
CPC分类号： B01F7/001 , B01F3/08 , B01F3/12 , B01F7/00341 , B01F2215/0422 , B01F2215/0431
摘要： A mixer impeller having high efficiency blades (24). The impeller may include a central hub (14) and a plurality of blades attached to and extending radially outwardly from the hub such that leading edges (38) thereof are inclined upwardly from trailing edges (50) thereof. Each of the blades may include a root (26) attached to the hub, a tip (28), a first crease (32) extending along substantially an entire length of the blade dividing the blade into a leading portion (34) and a trailing portion (36), the leading and trailing portions meeting at the first crease such that the leading portion is angled downwardly from the trailing portion, and a second crease (40) extending from a portion of the leading edge of the leading portion between the root and the tip diagonally along the leading portion to the tip, the second crease intersecting the tip at a point spaced from a point where the first crease intersects the tip, the second crease forming a tip portion of the leading portion that needs a remainder of the leading portion such that the tip portion is angled downwardly from the leading portion.
摘要翻译：一种具有高效叶片（24）的搅拌器叶轮。叶轮可以包括中心轮毂（14）和多个叶片，其连接到轮毂的径向向外并且从轮毂径向向外延伸，使得其前缘（38）从其后缘（50）向上倾斜。每个叶片可以包括附接到轮毂的根部（26），尖端（28），沿刀片的大致整个长度延伸的第一折痕（32），所述第一折痕将刀片分割成前导部分（34）所述前部和后部在所述第一折痕处相交，使得所述前部从所述后部向下成角度;以及第二折痕（40），所述第二折痕（40）从所述前部的所述前缘的前缘的一部分延伸到所述根部并且所述尖端沿着所述尖端的前导部分对角地，所述第二折痕在与所述第一折痕与所述尖端相交的点间隔开的点处与所述尖端相交，所述第二折痕形成所述引导部分的尖端部分，引导部分使得尖端部分从引导部分向下成角度。

3. 发明申请

WO2008059252A2 METHODS AND COMPOSITION FRO T CELL RECEPTORS WHICH RECOGNIZE 5T4 ANTIGEN 审中-公开
标题翻译：识别5T4抗原的方法和组合FRO T细胞受体
公开(公告)号：WO2008059252A2
公开(公告)日：2008-05-22
申请号：PCT/GB2007/004361
申请日：2007-11-15
申请人： OXFORD BIOMEDICA (UK) LIMITED , MYERS, Kevin , REDCHENKO, Irina , SHINGLER, William , HARROP, Richard , NAYLOR, Stuart , KINGSMAN, Alan , KINGSMAN, Susan
发明人： MYERS, Kevin , REDCHENKO, Irina , SHINGLER, William , HARROP, Richard , NAYLOR, Stuart , KINGSMAN, Alan , KINGSMAN, Susan
IPC分类号： C12Q1/68
CPC分类号： C07K14/4748
摘要： The present invention relates to the use of peptide epitopes of 5T4 antigen in the identification and isolation of T cell receptors which recognize 5T4 antigen.
摘要翻译：本发明涉及5T4抗原的肽表位在识别和分离识别5T4抗原的T细胞受体中的用途。

4. 发明申请

WO0029428A3 5T4 TUMOUR-ASSOCIATED ANTIGEN FOR USE IN TUMOUR IMMUNOTHERAPY 审中-公开
标题翻译：用于肿瘤免疫治疗的5T4肿瘤相关抗原
公开(公告)号：WO0029428A3
公开(公告)日：2000-11-09
申请号：PCT/GB9903859
申请日：1999-11-18
申请人： OXFORD BIOMEDICA LTD , CARROLL MILES WILLIAM , MYERS KEVIN ALAN
发明人： CARROLL MILES WILLIAM , MYERS KEVIN ALAN
IPC分类号： C12N15/09 , A61K38/00 , A61K39/00 , A61K48/00 , A61P15/00 , A61P35/00 , C07K7/06 , C07K14/065 , C07K14/47 , C07K19/00 , C12N15/12 , A61K38/17 , A61K39/275 , C07K14/82 , C12N15/863
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/53 , C12N2799/023
摘要： The present invention provides 5T4 tumour-associated antigen (TAA) for use in a method of immunotherapy of tumours. The invention also relates to a recombinant poxvirus vector from which at least one immune evasion gene has been deleted, which comprises a nucleic acid sequence encoding a 5T4 TAA and the use thereof in vaccinating against and in treating tumours.
摘要翻译：本发明提供了用于肿瘤免疫治疗方法的5T4肿瘤相关抗原（TAA）。本发明还涉及至少一种免疫逃避基因已被缺失的重组痘病毒载体，其包含编码5T4 TAA的核酸序列及其在疫苗接种和治疗肿瘤中的用途。

5. 发明申请

WO2014113473A2 WATER SAVING DEVICE 审中-公开
标题翻译：节水装置
公开(公告)号：WO2014113473A2
公开(公告)日：2014-07-24
申请号：PCT/US2014011685
申请日：2014-01-15
申请人： MYERS KEVIN P
发明人： MYERS KEVIN P
IPC分类号： G01F1/66
CPC分类号： G01F15/063 , B05B12/004 , B05B12/122 , G01F15/0755 , Y02A20/218
摘要： A water saving device including a housing and a processor disposed within the housing. The processor calculates a water volume expended over a period of time based on a predetermined volumetric flow rate and time. A sensor is disposed within the housing for sensing the presence of a user. The sensor is operably connected to the processor. The sensor generates a signal to cause the processor to begin calculating the water volume upon sensing the presence of a user. A display indicates the expended water volume and is operatively connected to the processor. The display shows a virtual water level which rises as time and water usage increases.
摘要翻译：一种节水装置，包括壳体和设置在壳体内的处理器。处理器基于预定的体积流量和时间来计算在一段时间内消耗的水量。传感器设置在壳体内以感测用户的存在。传感器可操作地连接到处理器。传感器产生信号，以使处理器在感测到用户的存在时开始计算水量。显示器指示耗水量并且可操作地连接到处理器。显示屏显示虚拟水位随着时间和用水量的增加而上升。

6. 发明申请

WO2008059252A3 METHODS AND COMPOSITION FRO T CELL RECEPTORS WHICH RECOGNIZE 5T4 ANTIGEN 审中-公开
公开(公告)号：WO2008059252A3
公开(公告)日：2008-12-04
申请号：PCT/GB2007004361
申请日：2007-11-15
申请人： OXFORD BIOMEDICA LTD , MYERS KEVIN , REDCHENKO IRINA , SHINGLER WILLIAM , HARROP RICHARD , NAYLOR STUART , KINGSMAN ALAN , KINGSMAN SUSAN
发明人： MYERS KEVIN , REDCHENKO IRINA , SHINGLER WILLIAM , HARROP RICHARD , NAYLOR STUART , KINGSMAN ALAN , KINGSMAN SUSAN
IPC分类号： C07K14/47
CPC分类号： C07K14/4748
摘要： The present invention relates to the use of peptide epitopes of 5T4 antigen in the identification and isolation of T cell receptors which recognize 5T4 antigen.

7. 发明申请

WO2003089649A1 EXPRESSION VECTOR COMPRISING A SIGNAL SEQUENCE AND AN AMINO-TERMINAL PEPTIDE TAG 审中-公开
标题翻译：包含信号序列和氨基端肽标签的表达载体
公开(公告)号：WO2003089649A1
公开(公告)日：2003-10-30
申请号：PCT/GB2003/001659
申请日：2003-04-17
申请人： OXFORD BIOMEDICA (UK) LIMITED , KINGSMAN, Susan , CARROLL, Miles , MYERS, Kevin , DRURY, Noel
发明人： KINGSMAN, Susan , CARROLL, Miles , MYERS, Kevin , DRURY, Noel
IPC分类号： C12N15/85
CPC分类号： C07K14/4748 , A61K38/00 , A61K2039/505 , C07K2319/02 , C07K2319/21 , C07K2319/40 , C07K2319/41 , C12N15/625 , C12N15/85 , C12N2840/203
摘要： The invention relates to an expression vector comprising an amino-terminal tag sequence and a signal sequence operably linked to a nucleotide sequence of interest, wherein the amino-terminal tag sequence is inserted between the signal sequence and the nucleotide sequence of interest.
摘要翻译：本发明涉及包含氨基末端标签序列和可操作地连接到目的核苷酸序列的信号序列的表达载体，其中将氨基末端标签序列插入信号序列和感兴趣的核苷酸序列之间。

8. 发明申请

WO2013184936A1 RUGGED AUTOMATED TRAINING SYSTEM AND METHODS 审中-公开
标题翻译：自动化培训系统及方法
公开(公告)号：WO2013184936A1
公开(公告)日：2013-12-12
申请号：PCT/US2013/044549
申请日：2013-06-06
申请人： MADORIN, Patrick, A. , MYERS, Kevin, P. , TRANQUILLO, Joseph, V.
发明人： MADORIN, Patrick, A. , MYERS, Kevin, P. , TRANQUILLO, Joseph, V.
IPC分类号： A01K15/00 , F41H11/12
CPC分类号： A01K15/02 , A01K5/02 , A01K27/002 , F41H11/132
摘要： Systems, kits, and methods for training animals. The system can include an animal training enclosure, an animal harness assembly, and a system controller assembly. The animal training enclosure can include a housing in which the animal to be trained is positioned, a stimuli delivery assembly that presents stimuli and distractors to the animal, and a primary reinforcement apparatus. The animal harness assembly can include a harness mounted on the animal, the harness housing a vibrotactile apparatus that can be used as a secondary reinforcement apparatus, an electronic compass that can measure orientation of the animal, and a wireless interface for communicating with the system controller assembly. The methods can include a method of training an animal using a secondary reinforcement positioned on a harness mounted on the animal, a method of concurrently training a plurality of animals, a method of detecting an unexploded landmine, and a method of demining a minefield.
摘要翻译：用于训练动物的系统，工具包和方法。该系统可以包括动物培训外壳，动物线束组件和系统控制器组件。动物训练罩可以包括其中待训练的动物被定位的壳体，向动物呈现刺激和牵引器的刺激递送组件以及主要的加强装置。动物线束组件可以包括安装在动物上的线束，该线束容纳可用作次级加强装置的振动触觉装置，可以测量动物的取向的电子罗盘，以及用于与系统控制器通信的无线接口部件。所述方法可以包括使用定位在安装在动物上的线束上的辅助加强物来训练动物的方法，同时训练多只动物的方法，检测未爆炸地雷的方法以及排雷雷达的方法。

9. 发明申请

WO2008154364A2 ADJUSTABLE INDEXABLE DRILL 审中-公开
标题翻译：可调指数钻头
公开(公告)号：WO2008154364A2
公开(公告)日：2008-12-18
申请号：PCT/US2008/066087
申请日：2008-06-06
申请人： VMAXX, INC. , MEYER, Mark, D. , MYERS, Kevin, D.
发明人： MEYER, Mark, D. , MYERS, Kevin, D.
IPC分类号： B23B51/02
CPC分类号： B23B51/048 , B23B2200/0419 , B23B2200/0438 , B23B2200/0447 , B23B2251/02 , B23B2251/50 , B23B2260/004 , B23B2260/038 , B23B2260/132 , Y10T408/86 , Y10T408/895 , Y10T408/906 , Y10T408/9095 , Y10T408/90993
摘要： An adjustable drill comprising a drill body having a longitudinal axis, comprising a face surface comprising an aperture extending into the drill body; a directional feature adjacent the aperture extending toward an edge of the drill body; a longitudinal gullet extending from the face surface along at least a portion of the drill body; a cartridge adjacent the face surface and selectively slidable along the directional feature comprising a slot along the directional feature; and a cutting face comprising an insert pocket positioned adjacent the edge of the drill body; a fastener through the slot into the aperture releasably affixing the cartridge to the drill body; and an insert releasably affixed in the insert pocket.
摘要翻译：一种可调钻头，其包括具有纵向轴线的钻体，所述钻头主体包括具有延伸到所述钻体中的孔的表面; 与所述孔相邻的朝向所述钻体的边缘延伸的定向特征; 沿所述钻孔体的至少一部分从所述表面延伸的纵向齿槽; 邻近所述面表面并且沿着所述方向特征选择性地滑动的盒，所述方向特征包括沿着所述方向特征的狭槽; 以及切割面，其包括邻近所述钻头本体的边缘定位的刀片槽; 穿过所述槽的紧固件将所述筒可释放地固定到所述钻体; 以及可释放地固定在刀片槽中的刀片。

10. 发明申请

WO2008059252A9 METHODS AND COMPOSITION FRO T CELL RECEPTORS WHICH RECOGNIZE 5T4 ANTIGEN 审中-公开
标题翻译：识别5T4抗原的方法和组合物FRO T细胞受体
公开(公告)号：WO2008059252A9
公开(公告)日：2008-09-18
申请号：PCT/GB2007004361
申请日：2007-11-15
申请人： OXFORD BIOMEDICA LTD , MYERS KEVIN , REDCHENKO IRINA , SHINGLER WILLIAM , HARROP RICHARD , NAYLOR STUART , KINGSMAN ALAN , KINGSMAN SUSAN
发明人： MYERS KEVIN , REDCHENKO IRINA , SHINGLER WILLIAM , HARROP RICHARD , NAYLOR STUART , KINGSMAN ALAN , KINGSMAN SUSAN
IPC分类号： C12Q1/68
CPC分类号： C07K14/4748
摘要： The present invention relates to the use of peptide epitopes of 5T4 antigen in the identification and isolation of T cell receptors which recognize 5T4 antigen.
摘要翻译：本发明涉及5T4抗原的肽表位在识别和分离识别5T4抗原的T细胞受体中的用途。

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