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1. 发明申请

WO2022076721A1 DUAL OPERATION GRASPING FORCEPS FOR ENDOSCOPE 审中-公开
公开(公告)号：WO2022076721A1
公开(公告)日：2022-04-14
申请号：PCT/US2021/054021
申请日：2021-10-07
申请人： MURPHY, Christopher
发明人： MURPHY, Christopher
IPC分类号： A61B17/30
摘要： A dual operation grasping forceps for use with an endoscope includes an elongated tube having a control mechanism along a first end, and a grasping section along a second end. The grasping section includes a plurality of resilient wire members each having a loop along a distal end. A cable is positioned through the loops to form a circular or triangular shape snare. The grasping members are independently connected to the control mechanism by a first operating wire, and the cable is independently connected to the control mechanism by a second operating wire. The control mechanism selectively moves the grasping section between a retracted position, an extended position and a closed position.

2. 发明申请

WO2015077156A3 MEDICAL SCOPE ATTACHMENT DEVICE AND SYSTEM 审中-公开
标题翻译：医疗范围附件设备和系统
公开(公告)号：WO2015077156A3
公开(公告)日：2015-11-12
申请号：PCT/US2014065747
申请日：2014-11-14
申请人： MURPHY CHRISTOPHER
发明人： MURPHY CHRISTOPHER
IPC分类号： A61B1/00
CPC分类号： A61B1/00158 , A61B1/00101 , A61B1/0014 , A61B1/01 , A61M25/0127
摘要： A medical scope attachment device and system includes one or more expandable rings, each having a resilient main body and an inside diameter defining a central opening that corresponds to a dimension of a medical scope. One or more sets of opposing magnetic elements are disposed within each of the rings. The system also includes a ring attachment device having a shelf that is interposed between a pair of opposing electromagnets. The ring attachment device functioning to transition the expandable rings between an expanded and non-expanded state to receive an existing medical scope.
摘要翻译：医学仪器连接装置和系统包括一个或多个可膨胀环，每个可膨胀环具有弹性主体和限定对应于医用观察器尺寸的中心开口的内径。一组或多组相对的磁性元件设置在每个环内。该系统还包括具有搁置在一对相对的电磁体之间的搁架的环形连接装置。环形附着装置用于使可扩张环在扩张状态和非扩张状态之间转变以接收现有的医学示波器。

3. 发明申请

WO2012166932A3 TREATING TEAR FILM DISORDERS WITH MESENCHYMAL STEM CELLS 审中-公开
标题翻译：用MESENCHYMAL STEM CELLS治疗眼膜疾病
公开(公告)号：WO2012166932A3
公开(公告)日：2013-01-31
申请号：PCT/US2012040228
申请日：2012-05-31
申请人： UNIV CALIFORNIA , MURPHY CHRISTOPHER J , RUSSELL PAUL , BORJESSON DORI L , WOOD JOSHUA A
发明人： MURPHY CHRISTOPHER J , RUSSELL PAUL , BORJESSON DORI L , WOOD JOSHUA A
IPC分类号： A61K35/28 , A61K35/407 , A61K35/44 , A61K35/55 , A61P27/04
CPC分类号： A61K35/28 , A61M5/00
摘要： This invention provides methods of preventing, reducing or inhibiting one or more symptoms of a tear film disorder by administration to a subject mesenchymal stem cells.
摘要翻译：本发明提供了通过给予受试者的间充质干细胞来预防，减少或抑制泪液病症的一种或多种症状的方法。

4. 发明申请

WO2007120302A3 LIQUID CRYSTALLINE SUBSTRATES FOR CULTURING CELLS 审中-公开
标题翻译：用于培养细胞的液晶基质
公开(公告)号：WO2007120302A3
公开(公告)日：2007-12-06
申请号：PCT/US2006061414
申请日：2006-11-30
申请人： WISCONSIN ALUMNI RES FOUND , ABBOTT NICHOLAS L , DE PABLO JUAN J , PALECEK SEAN P , LOCKWOOD NATHAN A , MOHR JEFFREY C , MURPHY CHRISTOPHER J , HUANG ELISE
发明人： ABBOTT NICHOLAS L , DE PABLO JUAN J , PALECEK SEAN P , LOCKWOOD NATHAN A , MOHR JEFFREY C , MURPHY CHRISTOPHER J , HUANG ELISE
IPC分类号： C12N5/00 , C12M3/00 , C12N5/0735
CPC分类号： C12N5/0068 , C12N5/0606 , C12N2533/50 , C12N2533/52 , C12N2533/54 , C12N2533/90
摘要： The present invention is directed to liquid crystalline substrates useful in the culture of cells and methods of their use. In certain embodiments, the invention provides methods and devices for imaging changes (e.g., reorganization) of extracellular matrix components by living cells.
摘要翻译：本发明涉及可用于细胞培养的液晶底物及其使用方法。在某些实施方案中，本发明提供用于成像活细胞对细胞外基质组分的改变（例如，重组）的方法和装置。

5. 发明申请

WO2007081326A3 BEAD BASED ASSAYS USING A LIQUID CRYSTAL REPORTER 审中-公开
公开(公告)号：WO2007081326A3
公开(公告)日：2007-07-19
申请号：PCT/US2006/000688
申请日：2006-01-09
申请人： PLATYPUS TECHNOLOGIES, LLC , ABBOTT, Nicholas , MURPHY, Christopher , ISREAL, Barbara , GHANTA, Jyothi , SOLTANINASSAB, Syrus
发明人： ABBOTT, Nicholas , MURPHY, Christopher , ISREAL, Barbara , GHANTA, Jyothi , SOLTANINASSAB, Syrus
IPC分类号： C09K19/02 , C09K19/52 , G02F1/13 , C12P19/12
摘要： The present invention relates to the field of detection of analytes, and in particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format.

6. 发明申请

WO2007056413A2 SYSTEM AND METHOD FOR UPDATING A STORAGE MEDIUM 审中-公开
标题翻译：用于更新存储介质的系统和方法
公开(公告)号：WO2007056413A2
公开(公告)日：2007-05-18
申请号：PCT/US2006/043413
申请日：2006-11-07
申请人： AUTUP, INC. , MURPHY, Christopher, P. , DADDONA, Thomas
发明人： MURPHY, Christopher, P. , DADDONA, Thomas
IPC分类号： G06F17/30
CPC分类号： G06F17/30315
摘要： A method for updating the information of a distributable storage medium that is coupled to a medium reader of a computer. The distributable medium including a recording of a first updateable application and the server including a recording of a second updateable application. The method comprising the steps of connecting the computer to a server, reading a status of the files of the first updateable application on the medium and a status of the files of the second updateable application on the server, comparing the status of the files of the first updateable application to the status of the files of the second updateable application, identifying updated files of the updateable application on the server and selectively transmitting the updated files to a database in the volatile memory of the computer, integrating the updateable application on the distributable storage medium with the updates from the updateable application on the server in volatile and non-volatile memory.
摘要翻译：一种用于更新耦合到计算机的介质读取器的可分发存储介质的信息的方法。可分发介质包括第一可更新应用程序的记录和包括第二可更新应用程序的记录的服务器。该方法包括以下步骤：将计算机连接到服务器，读取介质上的第一可更新应用程序的文件的状态以及服务器上第二可更新应用程序的文件的状态，比较文件的状态识别第二可更新应用程序的文件的状态的第一可更新应用程序，识别服务器上可更新应用程序的更新文件，并选择性地将更新的文件传送到计算机的易失性存储器中的数据库，将可更新应用程序集成在可分发存储器介于易失性和非易失性存储器中的可更新应用程序在服务器上的更新。

7. 发明申请

WO2006066184A3 METHODS AND COMPOSITIONS FOR ULTRA-HIGH THROUGHPUT SCREENING OF NATURAL PRODUCTS 审中-公开
标题翻译：用于天然产物超高速穿透筛选的方法和组合物
公开(公告)号：WO2006066184A3
公开(公告)日：2006-12-07
申请号：PCT/US2005045882
申请日：2005-12-16
申请人： CUBIST PHARM INC , BALTZ RICHARD H , MONAGHAN CATHERINE , MURPHY CHRISTOPHER , PENN JULIA , RITZ DANIEL , WRIGLEY STEVEN
发明人： BALTZ RICHARD H , MONAGHAN CATHERINE , MURPHY CHRISTOPHER , PENN JULIA , RITZ DANIEL , WRIGLEY STEVEN
IPC分类号： C12N1/20 , C12N5/00
CPC分类号： C12Q1/18 , C12N1/20
摘要： The present invention provides cells having more than two drug resistance genes and at least two different resistance genes that have been recombined into the chromosome of a cell. It also teaches the processes for preparing cells by recombining two or more different drug resistance genes into the chromosome of a cell. The invention further shows a screening method using the cells of described herein that may be used to accomplish high throughput screening of, among other things, natural products and/or whole cells isolated from the environment.
摘要翻译：本发明提供具有两个以上药物抗性基因的细胞和已经重组到细胞染色体中的至少两个不同的抗性基因。它还教导了通过将两个或多个不同的耐药基因重组到细胞的染色体中来制备细胞的过程。本发明还显示了使用本文所述的细胞的筛选方法，其可用于实现除了其它方面从天然产物和/或从环境分离的全细胞的高通量筛选。

8. 发明申请

WO2006085971A2 DETECTION OF ANALYTES 审中-公开
标题翻译：检测分析
公开(公告)号：WO2006085971A2
公开(公告)日：2006-08-17
申请号：PCT/US2005/023517
申请日：2005-07-01
申请人： PLATYPUS TECHNOLOGIES, LLC , ABBOTT, Nicholas , MURPHY, Christopher , ISRAEL, Barbara , ACHARYA, Bharat, Raj , JIN, Wiechang , ZAKRZEWSKI, Laura , VOLKMANN, Carla, J.
发明人： ABBOTT, Nicholas , MURPHY, Christopher , ISRAEL, Barbara , ACHARYA, Bharat, Raj , JIN, Wiechang , ZAKRZEWSKI, Laura , VOLKMANN, Carla, J.
IPC分类号： G01N33/00
CPC分类号： G01N31/22 , B01L3/5085 , B82Y15/00 , B82Y30/00 , B82Y40/00 , G01N21/64 , G01N33/54373
摘要： The present invention relates to the field of detection of analytes, and in particular to detection of organophosphates using a liquid crystal assay format and a variety of analytes in stand-off detection formats utilizing liquid crystals as part of reporting system. The present devices find use in detecting cumulative exposure to organophosphates in the aerosol phase.
摘要翻译：本发明涉及分析物的检测领域，特别涉及使用液晶测定形式的检测有机磷酸盐，以及利用液晶作为报告系统的一部分的间断检测形式的各种分析物。本发明的装置用于检测气溶胶相中有机磷酸盐的累积暴露。

9. 发明申请

WO2004017271A1 A FUNDS TRANSFER METHOD AND SYSTEM 审中-公开
标题翻译：基金转让方法与制度
公开(公告)号：WO2004017271A1
公开(公告)日：2004-02-26
申请号：PCT/IE2003/000111
申请日：2003-08-18
申请人： INTERNET PAYMENTS PATENTS LIMITED , FORAN, John, Anthony , CORCORAN, Joseph, Patrick , MURPHY, Christopher, Michael
发明人： FORAN, John, Anthony , CORCORAN, Joseph, Patrick , MURPHY, Christopher, Michael
IPC分类号： G07F19/00
CPC分类号： G06Q20/02 , G06Q20/04 , G06Q20/10 , G06Q20/403
摘要： A funds transfer method in a communications system between two entity computers where, depending on the transaction, one is a remitter computer and the other is a recevier computer. There is a systems server computer associated with an escrow account. Once a transaction has been agreed between the two computers, the systems server computer sets aside the funds in the escrow account, which funds are no longer available to the remitter computer which will often be operated by a buyer in the internet. Then the systems server computer issues two codes, namely, an initial initiation code and a funds release code respectively. The initiation code is sent to the receiver computer as confirmation of the availability of the funds in the escrow account. The other funds release code is with the remitter computer which sends the code to allow release of the funds on completion of a specified event occurring such as expiry of an agreed settlement date, acceptance by the remitter that the trade to which the transaction relates was satisfactorily completed or indeed any other agreed outcome. The invention allows for negotiations to take place between the parties if a dispute should arise by postponing the expected settlement data until, if no resolution of the dispute can be found by negotiation between the parties, a formal alternative dispute resolution procedure is set up.
摘要翻译：在两个实体计算机之间的通信系统中的资金转账方法，其中根据交易，一个是汇款计算机，另一个是收款机。有一个与代管帐户关联的系统服务器计算机。一旦两台计算机之间达成一项交易，系统服务器计算机就将代理资金存放在代管帐户中，这些资金不再适用于通常由互联网中的买方操作的汇款计算机。然后，系统服务器计算机分别发出两个代码，即初始启动代码和资金释放代码。启动代码将被发送到接收方计算机，以确认代管帐户中资金的可用性。其他资金发行代码是与汇款人计算机一起发送代码，以便在指定事件完成时发放资金，例如约定结算日期到期，汇款人接受交易所涉及的交易令人满意完成或其他任何约定的结果。本发明允许双方进行谈判，如果通过推迟预期的结算数据产生争议，直到双方当事人之间通过谈判解决争端的解决方案，则建立了正式的替代性争议解决程序。

10. 发明申请

WO2015017316A3 METHODS AND COMPOSITIONS FOR MODIFYING MUCOUS MEMBRANES 审中-公开
标题翻译：用于修饰MUCO膜的方法和组合物
公开(公告)号：WO2015017316A3
公开(公告)日：2015-03-26
申请号：PCT/US2014048391
申请日：2014-07-28
申请人： ABBOTT NICHOLAS L , MURPHY CHRISTOPHER J
发明人： ABBOTT NICHOLAS L , MURPHY CHRISTOPHER J
IPC分类号： A61K31/66
CPC分类号： A61K9/70 , A61K9/0014 , A61K9/0043 , A61K9/0048 , A61K9/006 , A61K31/00 , A61K31/095 , A61K31/375 , A61K31/66 , A61K31/70 , A61K31/7088 , A61K31/726 , A61K38/02 , A61K38/05 , A61K45/06
摘要： The present invention relates to methods and compositions for modifying mucous membranes. In particular, the present invention relates to treating diseases associated with mucous membranes by changing the intrinsic chemical composition and/or physical features of a target mucous membrane.
摘要翻译：本发明涉及用于修饰粘膜的方法和组合物。特别地，本发明涉及通过改变目标粘膜的固有化学成分和/或物理特征来治疗与粘膜相关的疾病。

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