会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 3. 发明申请
    • IMMUNOGENIC HIV COMPOSITIONS AND RELATED METHODS
    • 免疫原性HIV组合物及相关方法
    • WO2005021726A3
    • 2008-01-17
    • PCT/US2004027995
    • 2004-08-27
    • IMMUNE RESPONSE CORP INCMOSS RONALD B
    • MOSS RONALD B
    • A61K39/21A61K47/00C12N20060101C12Q1/70
    • A61K39/21A61K39/00A61K39/12A61K2039/5252A61K2039/5254A61K2039/545A61K2039/55A61K2039/555A61K2039/55561A61K2039/55566A61K2039/57A61K2039/62A61K2039/627C07K14/005C12N2740/16222C12N2740/16234
    • The invention provides immunogenic compositions which enhance the duration and strength of the immune response in a mammal. The immunogenic compositions contain an HIV antigen, an immunomer and an adjuvant. The HIV antigen can be a whole-killed HIV virus devoid of outer envelope protein gp120. Alternatively, the HIV antigen can be a whole-killed HIV virus, or a p24 antigen. Also provided are kits, the components of which, when combined, produce the immunogenic compositions of the invention. The invention also provides methods of making the immunogenic compositions, by combining an HIV antigen, an immunomer and optionally an adjuvant. The invention further provides a method of immunizing a mammal, by enhancing an immune response in the mammal by administering to the mammal an immunogenic composition containing an HIV antigen, an immunomer and optionally an adjuvant. Also provided is a method of inhibiting in a mammal by administering to the mammal an immunogenic composition containing an HIV antigen, an immunomer and optionally an adjuvant.
    • 本发明提供增强哺乳动物免疫反应持续时间和强度的免疫原性组合物。 免疫原性组合物含有HIV抗原,免疫体和佐剂。 HIV抗原可以是没有外包膜蛋白gp120的全杀死HIV病毒。 或者,HIV抗原可以是全杀死的HIV病毒或p24抗原。 还提供了试剂盒,其组分在组合时产生本发明的免疫原性组合物。 本发明还提供了通过组合HIV抗原,免疫体和任选的佐剂来制备免疫原性组合物的方法。 本发明还提供了通过向哺乳动物施用含有HIV抗原,免疫体和任选的佐剂的免疫原性组合来增强哺乳动物的免疫应答来免疫哺乳动物的方法。 还提供了通过向哺乳动物施用含有HIV抗原,免疫体和任选的佐剂的免疫原性组合物来抑制哺乳动物的方法。
    • 6. 发明申请
    • IMMUNOGENIC HIV COMPOSITIONS AND RELATED METHODS
    • 免疫原性HIV组合物及相关方法
    • WO2005021726A2
    • 2005-03-10
    • PCT/US2004/027995
    • 2004-08-27
    • THE IMMUNE RESPONSE CORPORATIONMOSS, Ronald, B.
    • MOSS, Ronald, B.
    • C12N
    • A61K39/21A61K39/00A61K39/12A61K2039/5252A61K2039/5254A61K2039/545A61K2039/55A61K2039/555A61K2039/55561A61K2039/55566A61K2039/57A61K2039/62A61K2039/627C07K14/005C12N2740/16222C12N2740/16234
    • The invention provides immunogenic compositions which enhance the duration and strength of the immune response in a mammal. The immunogenic compositions contain an HIV antigen, an immunomer and an adjuvant. The HIV antigen can be a whole-killed HIV virus devoid of outer envelope protein gp120. Alternatively, the HIV antigen can be a whole-killed HIV virus, or a p24 antigen. Also provided are kits, the components of which, when combined, produce the immunogenic compositions of the invention. The invention also provides methods of making the immunogenic compositions, by combining an HIV antigen, an immunomer and optionally an adjuvant. The invention further provides a method of immunizing a mammal, by enhancing an immune response in the mammal by administering to the mammal an immunogenic composition containing an HIV antigen, an immunomer and optionally an adjuvant. Also provided is a method of inhibiting in a mammal by administering to the mammal an immunogenic composition containing an HIV antigen, an immunomer and optionally an adjuvant.
    • 本发明提供增强哺乳动物免疫反应持续时间和强度的免疫原性组合物。 免疫原性组合物含有HIV抗原,免疫体和佐剂。 HIV抗原可以是没有外包膜蛋白gp120的全杀死HIV病毒。 或者,HIV抗原可以是全杀死的HIV病毒或p24抗原。 还提供了试剂盒,其组分在组合时产生本发明的免疫原性组合物。 本发明还提供了通过组合HIV抗原,免疫体和任选的佐剂来制备免疫原性组合物的方法。 本发明还提供了通过向哺乳动物施用含有HIV抗原,免疫体和任选的佐剂的免疫原性组合来增强哺乳动物的免疫应答来免疫哺乳动物的方法。 还提供了通过向哺乳动物施用含有HIV抗原,免疫体和任选的佐剂的免疫原性组合物来抑制哺乳动物的方法。