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1. 发明申请

WO2006084519A1 PUMP FOR MANUALLY DISPENSING A FLUID SUBSTANCE SEALED IN A CONTAINER 审中-公开
标题翻译：用于手动分配集装箱中密封的流体物质的泵
公开(公告)号：WO2006084519A1
公开(公告)日：2006-08-17
申请号：PCT/EP2005/056754
申请日：2005-12-13
申请人： LUMSON S.p.A. , RAMPINI, Gabriele , MORETTI, Matteo
发明人： RAMPINI, Gabriele , MORETTI, Matteo
IPC分类号： B05B11/00
CPC分类号： B05B11/305 , B05B11/004 , B05B11/3025
摘要： A pump enabling a fluid substance to be manually dispensed through a hollow stem (5) projecting from a hole m a ring cap (2) sealedly applied to one end of a pump. The stem can sealedly translate within said hole in the ring cap, which in its turn can be sealedly mounted on the mouth of a container containing the fluid substance to be dispensed.
摘要翻译：能够通过从密封地施加到泵的一端的环形盖（2）上的孔突出的中空杆（5）来手动分配流体物质的泵。杆可以在环形盖中的所述孔内密封地平移，该孔可以密封地安装在容纳待分配的流体物质的容器的口部上。

2. 发明申请

WO2010105641A1 DISPENSING DEVICE FOR A FLUID SUBSTANCE ENCLOSED IN A CONTAINER 审中-公开
标题翻译：用于在集装箱中装入的流体物质的分配装置
公开(公告)号：WO2010105641A1
公开(公告)日：2010-09-23
申请号：PCT/EP2009/002022
申请日：2009-03-19
申请人： LUMSON S.p.A. , MORETTI, Matteo
发明人： MORETTI, Matteo
IPC分类号： B05B11/00
CPC分类号： B05B11/3025
摘要： A dispensing device for a fluid substance enclosed in a container comprising a cup-shaped body closed by a ring cap and presenting an end at which a passageway is provided for dipping into fluid to be dispensed, said ring cap presenting a hole through which a stem for operating a piston is inserted and slides, said piston presenting a lower seal lip and an upper lip which sealedly slides along the inner surface of the cup-shaped body, which presents on its inner surface first and second means cooperating respectively with the first and second lip to connect the lower chamber to the upper chamber when the piston is in a lower end-of-stroke position, in order to enable the air contained in the lower chamber to escape during priming.
摘要翻译：一种用于封闭在容器中的流体物质的分配装置，包括由环形盖封闭的杯形体，并且具有端部，在该端部处设置有用于浸入要分配的流体的通道，所述环形盖呈现一个孔，通过该孔用于操作活塞的活塞被插入并滑动，所述活塞具有下密封唇和沿着杯状体的内表面密封地滑动的上唇，所述上唇在其内表面上呈现第一和第二装置，第一和第二装置分别与第一和当活塞处于下行程位置时，将下腔室连接到上腔室的第二唇缘，以使得包含在下腔室中的空气能够在起动期间逸出。

3. 发明申请

WO2009047021A1 DEVICE FOR DISPENSING, BY MEANS OF A PUMP, FLUID SUBSTANCES CONTAINED UNDER AIRTIGHT CONDITIONS IN A DEFORMABLE BAG HOUSED IN A RIGID CONTAINER 审中-公开
标题翻译：用于通过泵的分配的装置，包含在刚性容器中的可变形袋中的空气条件下的流体物质
公开(公告)号：WO2009047021A1
公开(公告)日：2009-04-16
申请号：PCT/EP2008/057237
申请日：2008-06-10
申请人： LUMSON S.p.A. , MORETTI, Matteo
发明人： MORETTI, Matteo
IPC分类号： B05B11/00 , B65D83/00 , B29C49/08
CPC分类号： B05B11/0043 , B05B11/0097 , B05B11/3047 , B29C49/06 , B29C49/24 , B29C2049/2404 , B29L2009/001 , B29L2031/7158
摘要： Device for dispensing, by means of a manually operable pump, fluid substances contained in a deformable bag housed in a rigid container. The bag has a mouth with a projecting flange with which the pump engages in coupling to the flange, and which causes the bag to be extracted from the container when the pump is separated from the container after the bag has been emptied.
摘要翻译：用于通过手动操作的泵分配容纳在容纳在刚性容器中的可变形袋中的流体物质的装置。该袋具有一个具有突出凸缘的口，泵与该法兰接合，并且当袋子被排空之后，当泵与容器分离时，这使得袋子从容器中取出。

4. 发明申请

WO2008098165A3 OSCILLATING CELL CULTURE BIOREACTOR 审中-公开
标题翻译：振荡细胞培养生物反应器
公开(公告)号：WO2008098165A3
公开(公告)日：2008-10-02
申请号：PCT/US2008053411
申请日：2008-02-08
申请人： MASSACHUSETTS INST TECHNOLOGY , MORETTI MATTEO G , FREED LISA E , LANGER ROBERT S
发明人： MORETTI MATTEO G , FREED LISA E , LANGER ROBERT S
IPC分类号： C12M1/02
CPC分类号： C12M23/02 , A61L27/3895 , C12M21/08 , C12M23/06 , C12M23/24 , C12M25/14 , C12M27/10
摘要： Methods and devices for cell or tissue culture are provided. One aspect provides a bioreactor having a gas permeable, closed-loop chamber for cell or tissue culture, and an oscillating means for moving the gas permeable, closed-loop chamber bidirectionally along an axis horizontal to an axis normal to the closed-loop chamber to force convection of cells and fluid in the gas permeable, closed-loop chamber. The bioreactor optionally includes a tissue engineering scaffold, an inlet means, an outlet means, and integrated sensors. Another aspect provides a bioreactor having a plurality of gas permeable, closed-loop chambers for cell or tissue culture. Methods of culturing cells and producing tissue constructs are also provided.
摘要翻译：提供了用于细胞或组织培养的方法和装置。一个方面提供了具有用于细胞或组织培养的气体可渗透闭环腔室的生物反应器以及用于沿着水平方向垂直于闭环腔室的轴线双向移动气体可渗透闭环腔室的振荡装置，气体可渗透的闭环腔室中的细胞和流体的强制对流。生物反应器可选地包括组织工程支架，入口装置，出口装置和集成传感器。另一方面提供了具有用于细胞或组织培养的多个可透气的闭环室的生物反应器。还提供了培养细胞和产生组织构建体的方法。

5. 发明申请

WO2010105642A1 DISPENSING DEVICE FOR FLUID SUBSTANCES 审中-公开
标题翻译：流体物质分配装置
公开(公告)号：WO2010105642A1
公开(公告)日：2010-09-23
申请号：PCT/EP2009/002023
申请日：2009-03-19
申请人： LUMSON S.p.A. , MORETTI, Matteo
发明人： MORETTI, Matteo
IPC分类号： B65D83/16 , B05B11/00
CPC分类号： B05B11/0067 , B05B11/0072 , B65D83/7535
摘要： A dispensing device for fluid substances, comprising a pushbutton (1) in which a chamber (3) is provided housing a piston (12), the piston being loaded by an elastic means (14) such as to urge a front projecting appendix (16) thereof into a dispensing hole (15) for said substance, to hence sealedly close it, the pushbutton presenting a seat (10) enabling a hollow stem to be coupled therethrough through which the pressurized substance is fed to said device, characterised in that in said chamber (3) there is housed an at least partially cylindrical member (11) in the interior of which said piston slides, in said member there being provided at least one passageway opening (22) to the front of said piston and communicating with the bore of said stem when the device is positioned on the pump.
摘要翻译：一种用于流体物质的分配装置，包括按钮（1），其中设有容纳活塞（12）的腔室（3），所述活塞由弹性装置（14）装载，以便推动前突出的附件（16））插入到用于所述物质的分配孔（15）中，从而密封地关闭它，所述按钮具有座（10），所述座（10）能够连接中空杆，通过所述座（10）将所述加压物质供给到所述装置，其特征在于，所述腔室（3）中容纳有至少部分圆柱形的构件（11），其中所述活塞滑动，在所述构件中，在所述构件中设置有至少一个通向所述活塞前部的通道开口（22）当设备定位在泵上时，所述杆的孔。

6. 发明申请

WO2008098165A9 OSCILLATING CELL CULTURE BIOREACTOR 审中-公开
标题翻译：振荡细胞培养物生物反应器
公开(公告)号：WO2008098165A9
公开(公告)日：2008-11-27
申请号：PCT/US2008053411
申请日：2008-02-08
申请人： MASSACHUSETTS INST TECHNOLOGY , MORETTI MATTEO G , FREED LISA E , LANGER ROBERT S
发明人： MORETTI MATTEO G , FREED LISA E , LANGER ROBERT S
IPC分类号： C12M1/02
CPC分类号： C12M23/02 , A61L27/3895 , C12M21/08 , C12M23/06 , C12M23/24 , C12M25/14 , C12M27/10
摘要： Methods and devices for cell or tissue culture are provided. One aspect provides a bioreactor having a gas permeable, closed-loop chamber for cell or tissue culture, and an oscillating means for moving the gas permeable, closed-loop chamber bidirectionally along an axis horizontal to an axis normal to the closed-loop chamber to force convection of cells and fluid in the gas permeable, closed-loop chamber. The bioreactor optionally includes a tissue engineering scaffold, an inlet means, an outlet means, and integrated sensors. Another aspect provides a bioreactor having a plurality of gas permeable, closed-loop chambers for cell or tissue culture. Methods of culturing cells and producing tissue constructs are also provided.
摘要翻译：提供了细胞或组织培养的方法和装置。一个方面提供了一种生物反应器，其具有用于细胞或组织培养的气体可渗透的闭环腔室，以及用于沿着垂直于垂直于闭环腔室的轴线的轴线双向移动气体可渗透的闭环腔室的振荡装置，在气体可渗透的闭环室中强制对流细胞和流体。生物反应器任选地包括组织工程支架，入口装置，出口装置和集成的传感器。另一方面提供了一种生物反应器，其具有用于细胞或组织培养的多个可透气的闭环腔室。还提供了培养细胞和产生组织构建体的方法。

7. 发明申请

WO2008098165A2 OSCILLATING CELL CULTURE BIOREACTOR 审中-公开
标题翻译：振荡细胞培养生物反应器
公开(公告)号：WO2008098165A2
公开(公告)日：2008-08-14
申请号：PCT/US2008/053411
申请日：2008-02-08
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , MORETTI, Matteo G. , FREED, Lisa E. , LANGER, Robert S.
发明人： MORETTI, Matteo G. , FREED, Lisa E. , LANGER, Robert S.
IPC分类号： C12M1/02
CPC分类号： C12M23/02 , A61L27/3895 , C12M21/08 , C12M23/06 , C12M23/24 , C12M25/14 , C12M27/10
摘要： Methods and devices for cell or tissue culture are provided. One aspect provides a bioreactor having a gas permeable, closed-loop chamber for cell or tissue culture, and an oscillating means for moving the gas permeable, closed-loop chamber bidirectionally along an axis horizontal to an axis normal to the closed-loop chamber to force convection of cells and fluid in the gas permeable, closed-loop chamber. The bioreactor optionally includes a tissue engineering scaffold, an inlet means, an outlet means, and integrated sensors. Another aspect provides a bioreactor having a plurality of gas permeable, closed-loop chambers for cell or tissue culture. Methods of culturing cells and producing tissue constructs are also provided.
摘要翻译：提供了用于细胞或组织培养的方法和装置。一个方面提供了具有用于细胞或组织培养的气体可渗透闭环腔室的生物反应器以及用于沿着水平方向垂直于闭环腔室的轴线双向移动气体可渗透闭环腔室的振荡装置，气体可渗透的闭环腔室中的细胞和流体的强制对流。生物反应器可选地包括组织工程支架，入口装置，出口装置和集成传感器。另一方面提供了具有用于细胞或组织培养的多个可透气的闭环室的生物反应器。还提供了培养细胞和产生组织构建体的方法。

8. 发明申请

WO2007101484A1 PUMP FOR MANUALLY DISPENSING A FLUID SUBSTANCE SEALED IN A CONTAINER 审中-公开
标题翻译：用于手动分配集装箱中密封的流体物质的泵
公开(公告)号：WO2007101484A1
公开(公告)日：2007-09-13
申请号：PCT/EP2006/069558
申请日：2006-12-11
申请人： LUMSON S.P.A. , MORETTI, Matteo , RAMPINI, Gabriele
发明人： MORETTI, Matteo , RAMPINI, Gabriele
IPC分类号： B05B11/00
CPC分类号： B05B11/3025 , B05B11/3061
摘要： A pump enabling a fluid substance to be manually dispensed through a hollow stem (5) projecting from a hole in a ring cap sealedly applied to one end of a pump, the stem (5) being sealedly translate within said hole in the ring cap, which in its turn can be sealedly mounted on the mouth of a container containing the fluid substance to be dispensed.
摘要翻译：一种能够通过从密封地施加到泵的一端的环形盖中的孔突出的中空杆（5）来手动分配流体物质的泵，所述杆（5）在所述环盖的所述孔内被密封地平移，其又可以密封地安装在容纳待分配的流体物质的容器的口部上。

9. 发明申请

WO2006081879A1 MIXTURE OF LOW-BOILING LIQUIDS WITH PRODUCTS DISPENSABLE BY PUMPS 审中-公开
标题翻译：低沸点液体混合物与泵可分配的产品
公开(公告)号：WO2006081879A1
公开(公告)日：2006-08-10
申请号：PCT/EP2005/055466
申请日：2005-10-21
申请人： LUMSON S.p.A. , RAMPINI, Gabriele , MORETTI, Matteo
发明人： RAMPINI, Gabriele , MORETTI, Matteo
IPC分类号： B05B11/00 , B65D83/14 , B65D47/34
CPC分类号： B05B11/004
摘要： Fluid mixture which comprises at least one low-boiling liquid, and which during use generates a low vapour pressure, said mixture being dispensable by a manually operated dispensing pump mounted on a hermetically sealed container of this mixture. The low vapour pressure developed by the low-boiling liquid is such as to prevent a vacuum being created in the container interior when the mixture is dispensed by the pump, in order to allow correct pump operation.
摘要翻译：包含至少一种低沸点液体的流体混合物，并且在使用期间产生低蒸气压，所述混合物由安装在该混合物的气密密封容器上的手动操作的分配泵是可分配的。由低沸点液体产生的低蒸汽压力是为了防止当混合物被泵分配时在容器内部产生真空，以便允许正确的泵操作。

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