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1. 发明申请

WO2016100044A1 DEVICES, SYSTEMS, AND METHODS FOR VISUALIZATION OF MOVING TISSUE WITH STROBED ILLUMINATION 审中-公开
标题翻译：用于可视化移动组织的装置，系统和方法，具有有限的照明
公开(公告)号：WO2016100044A1
公开(公告)日：2016-06-23
申请号：PCT/US2015/064789
申请日：2015-12-09
申请人： NOVARTIS AG , HEEREN, Tammo , MCDONELL, Brian, William
发明人： HEEREN, Tammo , MCDONELL, Brian, William
IPC分类号： A61F9/007
CPC分类号： A61F9/00745 , A61B2090/306 , A61F9/00736
摘要： Devices, systems, and methods for visualizing moving tissue with strobed light are provided. A surgical system includes a surgical device configured to operate on anatomy at a first frequency such that the anatomy moves at the first frequency when the surgical device is in contact therewith; and a light source configured to provide pulses of light at a second frequency to illuminate the moving anatomy; wherein the second frequency is different than the first frequency. A method of treating an ophthalmic condition includes operating a surgical device at a first frequency such that anatomy moves at the first frequency when the surgical device is contacted therewith; and controlling a light source to provide pulses of light at a second frequency to illuminate the moving anatomy; wherein the second frequency is different than the first frequency. An ophthalmic surgical system includes a cutting probe, a strobed light source, and a computing device.
摘要翻译：提供了用频闪显示可视化运动组织的装置，系统和方法。手术系统包括外科装置，其被配置为以第一频率在解剖学上操作，使得解剖结构在手术装置与其接触时以第一频率移动; 以及光源，被配置为以第二频率提供脉冲以照亮所述移动的解剖结构; 其中所述第二频率不同于所述第一频率。治疗眼科疾病的方法包括以第一频率操作手术装置，使得解剖结构在手术装置与其接触时以第一频率移动; 以及控制光源以提供第二频率的脉冲以照亮所述移动的解剖结构; 其中所述第二频率不同于所述第一频率。眼科手术系统包括切割探针，频闪光源和计算装置。

2. 发明申请

WO2012087526A1 DEVICE FOR AT LEAST ONE OF INJECTION OR ASPIRATION 审中-公开
标题翻译：用于至少一次注射或吸入的装置
公开(公告)号：WO2012087526A1
公开(公告)日：2012-06-28
申请号：PCT/US2011/062776
申请日：2011-12-01
申请人： ALCON RESEARCH, LTD. , AULD, Jack , MCDONELL, Brian William , WHEATLEY, Barry Lynn
发明人： AULD, Jack , MCDONELL, Brian William , WHEATLEY, Barry Lynn
IPC分类号： A61M5/315
CPC分类号： A61M5/1452 , A61F9/007 , A61M5/14546 , A61M5/14566 , A61M5/16877 , A61M5/20 , A61M5/2053 , A61M5/31515 , A61M5/31583 , A61M2205/0294 , A61M2209/01 , A61M2210/0612
摘要： Devices, systems, and associated methods that facilitate the injection and/or aspiration of precisely controlled volumes of fluids at precisely controlled rates are provided. In some implementations, an apparatus may include a syringe and a lead screw connected to a plunger of the syringe. A ratchet gear may be connected to the lead screw. A mechanism may also be included to oscillate a frame in a direction perpendicular to a longitudinal axis of the lead screw such that one or more pawls of the frame engage the teeth of the ratchet gear in a manner that results in rotation of the ratchet gear in a single direction for controlled linear displacement of the plunger.
摘要翻译：提供了以精确控制的速率促进精确控制体积的流体的注入和/或抽吸的装置，系统和相关方法。在一些实施方案中，装置可以包括注射器和连接到注射器的柱塞的导螺杆。棘轮可以连接到导螺杆。还可以包括一种机构，以便在垂直于导螺杆的纵向轴线的方向上振动框架，使得框架的一个或多个棘爪以棘轮的齿轮啮合，导致棘轮的旋转用于柱塞的受控线性位移的单个方向。

3. 发明申请

WO2011022487A1 MAGNETICALLY DRIVEN HIGH SPEED PNEUMATIC VALVE 审中-公开
标题翻译：磁力驱动高速气动阀
公开(公告)号：WO2011022487A1
公开(公告)日：2011-02-24
申请号：PCT/US2010/045901
申请日：2010-08-18
申请人： ALCON RESEARCH, LTD. , HUCULAK, John Christopher , MCDONELL, Brian William
发明人： HUCULAK, John Christopher , MCDONELL, Brian William
IPC分类号： A61F9/007 , F01L9/02 , A61B17/00 , A61M1/00
CPC分类号： F16K31/082 , A61B2017/00544 , A61F9/00736
摘要： A high speed pneumatic valve has a housing enclosing a cavity with an inlet port and an outlet port. A permanently magnetized armature is located in the cavity. The permanently magnetized armature moves between a first, open position and a second, closed position. A coil and magnetic core assembly is located near the armature in the housing. A first voltage applied across the coil results in a magnetic field with a first polarity being induced in the magnetic core thereby attracting the armature toward the magnetic core and away from the outlet port. A second voltage applied across the coil results in a magnetic field with a second, opposite polarity being induced in the magnetic core thereby repelling the armature away from the magnetic core and toward the outlet port.
摘要翻译：高速气动阀具有包围具有入口和出口的空腔的壳体。永久磁化的电枢位于空腔中。永久磁化的电枢在第一，打开位置和第二闭合位置之间移动。线圈和磁芯组件位于壳体中的电枢附近。施加在线圈上的第一电压导致在磁芯中感应出第一极性的磁场，从而将电枢吸引到磁芯并远离出口。施加在线圈两端的第二电压导致具有在磁芯中感应的第二相反极性的磁场，从而将电枢排斥离开磁芯并朝向出口。

4. 发明申请

WO2016073194A1 DUAL MODE VITRECTOMY SURGICAL SYSTEM 审中-公开
标题翻译：双模式手术系统
公开(公告)号：WO2016073194A1
公开(公告)日：2016-05-12
申请号：PCT/US2015/056571
申请日：2015-10-21
申请人： NOVARTIS AG , MCDONELL, Brian William
发明人： MCDONELL, Brian William
IPC分类号： A61F9/007
CPC分类号： A61F9/00763 , A61B17/00 , A61B2017/00539
摘要： An ophthalmic surgical probe for treating an eye of a patient includes a body, a cutting element extending distally from the body (the cutting element having a sleeve member with a port at an end), an inner member disposed within the sleeve member (the inner member being movable axially with respect to the sleeve member to open and close the port), and an actuating element secured to the inner member (the actuating member configured for operation in both a resonant mode and a nonresonant mode).
摘要翻译：一种用于治疗患者眼睛的眼科手术探针包括主体，从身体向远侧延伸的切割元件（切割元件具有在端部具有端口的套筒元件），设置在套筒元件内部的内部元件构件相对于套筒构件轴向移动以打开和关闭端口）以及固定到内部构件的致动构件（构造成在谐振模式和非共振模式中操作的致动构件）。

5. 发明申请

WO2016081133A1 DOUBLE-ACTING VITREOUS PROBE WITH CONTOURED PORT 审中-公开
标题翻译：双面操作具有轮廓端口的维修探头
公开(公告)号：WO2016081133A1
公开(公告)日：2016-05-26
申请号：PCT/US2015/056572
申请日：2015-10-21
申请人： NOVARTIS AG , FARLEY, Mark , MCDONELL, Brian William
发明人： FARLEY, Mark , MCDONELL, Brian William
IPC分类号： A61F9/007
CPC分类号： A61F9/00763 , A61B2218/007
摘要： A vitrectomy probe includes a hand-graspable body and an outer tube extending from the hand-graspable body. The outer tube includes a closed distal end and a first port sized to receive 5 tissue. The vitrectomy probe also includes an inner tube within the outer tube with a second port that is selectively alignable with a portion of the first port to allow fluid flow and uniquely sized to increase fluid flow. The inner tube includes a distal tip with a cutting edge on each of the distal and proximal sides of the tip. The distal tip has a smaller diameter than that of the inner 10 tube at a proximal side of the second port. The proximal side of the second port includes a guiding surface that slidably bears on an inner surface of the outer tube to prevent the distal tip from excessively protruding from the first port of the outer tube.
摘要翻译：玻璃体切割探针包括可手握的主体和从手持物体延伸的外管。外管包括封闭的远端和尺寸适于接收5个组织的第一端口。玻璃体切割探针还包括在外管内的内管，其具有与第一端口的一部分选择性对准的第二端口，以允许流体流动并且独特地设计尺寸以增加流体流动。内管包括在尖端的远侧和近侧各自具有切割边缘的远端。远侧末端在第二端口的近侧具有比内部管10的直径小的直径。第二端口的近侧包括可滑动地承载在外管的内表面上的引导表面，以防止远端从外管的第一端口过度地突出。

6. 发明申请

WO2012154226A1 SURGICAL PROBE WITH INCREASED FLUID FLOW 审中-公开
标题翻译：具有增加流体流量的外科手术
公开(公告)号：WO2012154226A1
公开(公告)日：2012-11-15
申请号：PCT/US2012/021010
申请日：2012-01-12
申请人： ALCON RESEARCH, LTD. , AULD, Jack Robert , MCDONELL, Brian William
发明人： AULD, Jack Robert , MCDONELL, Brian William
IPC分类号： A61B17/32
CPC分类号： A61F9/00763
摘要： A surgical probe, e.g. a vitrectomy probe, and methods of making the same are disclosed. An exemplary surgical probe may include a tubular body and a cutting tool that is received within the body. The tubular body may define a cutting aperture that is adjacent a first end of the body and a fluid passage that extends through the body from the cutting aperture to a second end of the body. The cutting tool may be received within the body and disposed within the fluid passage. The cutting tool is generally configured to allow fluid flow through the cutting tool. The cutting tool may include a body portion and a blade portion that is configured to cut material entering the cutting aperture. The body portion may extend only partially about an inner circumference of the tubular body.
摘要翻译：手术探针，例如玻璃体切割探针及其制备方法。示例性的手术探针可以包括管体和被接纳在体内的切割工具。管状体可以限定与主体的第一端相邻的切割孔，以及从主体的切割孔延伸穿过主体的第二端的流体通道。切割工具可以被容纳在主体内并且设置在流体通道内。切削工具通常构造成允许流体流过切削工具。切割工具可以包括主体部分和刀片部分，其被配置为切割进入切割孔的材料。主体部分可以仅部分地围绕管状体的内圆周延伸。

7. 发明申请

WO2012087528A1 DEVICE FOR AT LEAST ONE OF INJECTION OR ASPIRATION 审中-公开
标题翻译：用于至少一次注射或吸入的装置
公开(公告)号：WO2012087528A1
公开(公告)日：2012-06-28
申请号：PCT/US2011/062780
申请日：2011-12-01
申请人： ALCON RESEARCH, LTD. , WHEATLEY, Barry, Lynn , MCDONELL, Brian William
发明人： WHEATLEY, Barry, Lynn , MCDONELL, Brian William
IPC分类号： A61M5/00
CPC分类号： A61M5/1452 , A61F9/007 , A61M5/14546 , A61M5/14566 , A61M5/16877 , A61M5/20 , A61M5/2053 , A61M5/31515 , A61M5/31583 , A61M2205/0294 , A61M2209/01 , A61M2210/0612
摘要： Micro-volume devices, systems, and associated methods that facilitate the injection or aspiration of precisely controlled volumes of materials at precisely controlled rates are provided. In one embodiment, a micro-volume device includes a syringe and a lead screw connected to a plunger of the syringe. A mechanical interface is connected to the lead screw and includes a first set of cams adjacent a proximal portion and a second set of cams adjacent a distal portion. A mechanism is configured to oscillate a structure in a direction parallel to a longitudinal axis of the lead screw such that one or more projections of the structure to alternatively engage cams of the first and second sets of cams in a manner that results in rotation of the mechanical interface in a single direction for highly controlled linear displacement of the plunger.
摘要翻译：提供了以精确控制的速率促进精确控制体积的材料的注入或抽吸的微体积装置，系统和相关方法。在一个实施例中，微体积装置包括注射器和连接到注射器柱塞的导螺杆。机械接口连接到导螺杆，并且包括邻近近端部分的第一组凸轮和邻近远端部分的第二组凸轮。一种机构被配置成使结构在平行于导螺杆的纵向轴线的方向上振荡，使得该结构的一个或多个突起交替地接合第一组凸轮和第二组凸轮的凸轮，导致机械接口在单一方向用于柱塞的高度可控的线性位移。

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