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1. 发明申请

WO2007100728A3 MANNOSE DERIVATIVES FOR KILLING TUMOR CELLS 审中-公开
标题翻译：用于杀死肿瘤细胞的MANNOSE衍生物
公开(公告)号：WO2007100728A3
公开(公告)日：2008-10-09
申请号：PCT/US2007004845
申请日：2007-02-26
申请人： UNIV MIAMI , LAMPIDIS THEODORE J , KURTOGLU METIN , MATHER JOHN
发明人： LAMPIDIS THEODORE J , KURTOGLU METIN , MATHER JOHN
IPC分类号： A01N43/04 , A61K31/70
CPC分类号： A61K31/70 , A61K45/06 , A61K2300/00
摘要： A method for treating cancer by killing selected tumor cells such as human breast, non-small cell lung cancer cells, pancreatic cancer cells, osteosarcoma cancer cells, and glioblastoma cells, includes administering to a patient in need of treatment, an effective amount of at least one mannose analog such as 2-DG or 2-FM or 2-CM. The killing is believed to be due to an interference with glycosylation. A theranostic method includes determining whether a patient. cancer tumor sample comprises cells sensitive to killing to at least one mannose analog due to an interference with glycosylation.
摘要翻译：通过杀死所选择的肿瘤细胞如人乳腺癌，非小细胞肺癌细胞，胰腺癌细胞，骨肉瘤癌细胞和成胶质细胞瘤细胞来治疗癌症的方法包括向需要治疗的患者施用有效量的至少一种甘露糖类似物如2-DG或2-FM或2-CM。这种杀戮被认为是由于对糖基化的干扰。鉴别方法包括确定患者是否。癌症肿瘤样品包含由于干扰糖基化而对至少一种甘露糖类似物的杀伤敏感的细胞。

2. 发明申请

WO2007100728A2 MANNOSE DERIVATIVES FOR KILLING TUMOR CELLS 审中-公开
标题翻译：用于杀死肿瘤细胞的MANNOSE衍生物
公开(公告)号：WO2007100728A2
公开(公告)日：2007-09-07
申请号：PCT/US2007/004845
申请日：2007-02-26
申请人： UNIVERSITY OF MIAMI , LAMPIDIS, Theodore, J. , KURTOGLU, Metin , MATHER, John
发明人： LAMPIDIS, Theodore, J. , KURTOGLU, Metin , MATHER, John
IPC分类号： A61K31/70
CPC分类号： A61K31/70 , A61K45/06 , A61K2300/00
摘要： A method for treating cancer by killing selected tumor cells such as human breast, non-small cell lung cancer cells, pancreatic cancer cells, osteosarcoma cancer cells, and glioblastoma cells, includes administering to a patient in need of treatment, an effective amount of at least one mannose analog such as 2-DG or 2-FM or 2-CM. The killing is believed to be due to an interference with glycosylation. A theranostic method includes determining whether a patient. cancer tumor sample comprises cells sensitive to killing to at least one mannose analog due to an interference with glycosylation.
摘要翻译：通过杀死所选择的肿瘤细胞如人乳腺癌，非小细胞肺癌细胞，胰腺癌细胞，骨肉瘤癌细胞和成胶质细胞瘤细胞来治疗癌症的方法包括向需要治疗的患者施用有效量的至少一种甘露糖类似物如2-DG或2-FM或2-CM。这种杀戮被认为是由于对糖基化的干扰。鉴别方法包括确定患者是否。癌症肿瘤样品包含由于干扰糖基化而对至少一种甘露糖类似物的杀伤敏感的细胞。

3. 发明申请

WO2007093831A1 SECURITY DEVICE 审中-公开
标题翻译：安全装置
公开(公告)号：WO2007093831A1
公开(公告)日：2007-08-23
申请号：PCT/GB2007/050070
申请日：2007-02-16
申请人： XTAG LIMITED , MATHER, John , WILKINSON, Philip
发明人： MATHER, John , WILKINSON, Philip
IPC分类号： G08B21/22
CPC分类号： G08B21/22 , G08B21/0286
摘要： The invention relates to security devices. In particular, but not exclusively, the invention relates to security devices comprising a tag to be worn by persons including babies, patients and other objects whose movements are to be monitored. A tamper-proof security device comprises a tag and a strap, the device comprising means for attaching the strap to the tag, such that the strap forms a loop, the strap further comprising at least one electrical conductor disposed along at least a portion of a length of the strap, the means for attaching the strap to the tag further comprising means for making electrical contact between the tag and the at least one electrical conductor of the strap such that an electrical flow path is provided through said at least one conductor between a plurality of electrical contacts of the tag, and wherein the electrical conductor comprises a conducting polymer material.
摘要翻译：本发明涉及安全装置。特别地但并不排他地，本发明涉及安全装置，其包括由包括婴儿，患者和其运动要监视的其他物体的人员穿戴的标签。防篡改安全装置包括标签和带，该装置包括用于将带绑定到标签上的装置，使得带形成环，所述带还包括至少一个电导体，沿着至少一部分带的长度，用于将带附接到标签的装置还包括用于在标签与带的至少一个电导体之间进行电接触的装置，使得通过所述至少一个导体提供电流路径标签的多个电触点，并且其中电导体包括导电聚合物材料。

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