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    • 1. 发明申请
    • ELECTRONIC VOTING SYSTEMS
    • 电子投票系统
    • WO2005093671A3
    • 2006-04-27
    • PCT/GB2005000231
    • 2005-01-24
    • CRYPTOMATHIC ASMARTIN PHILIP JOHNSALOMONSEN GORMGROTH JENS
    • SALOMONSEN GORMGROTH JENS
    • G07C13/00H04L9/32
    • H04L9/3218G07C13/00H04L2209/463
    • This invention is generally concerned with systems and methods for electronic voting. An electronic voting system, the system comprising: a voting device configured to generate, in response to a voter selection for each of a plurality of voters an encrypted electronic ballot and a printed ballot, both having voter selection data indicating a said voter's choice, said electronic ballot including information to link it to said printed ballot and said printed ballot including information to link it to said electronic ballot; an electronic vote decryption system configured to receive electronic ballots from said voting device and to decrypt said encrypted electronic ballots; including said linking information; and a voting verification system configured to receive decrypted voter selection data and linking information from said vote decryption system, to receive voter selection data and linking information from said printed ballots and to compare voters choices for a sample of said printed and electronic ballots linked by said linking information, to verify the voting.
    • 本发明一般涉及用于电子投票的系统和方法。 一种电子投票系统,该系统包括:投票设备,被配置为响应于多个投票者中的每一个的选民选择,生成具有指示所述投票者选择的选举者选择数据的加密电子投票和打印投票,所述投票设备 电子投票,包括将其连接到所述打印的投票和所述打印的投票的信息,包括将其链接到所述电子投票的信息; 电子投票解密系统,被配置为从所述投票设备接收电子投票并解密所述加密的电子投票; 包括所述链接信息; 以及投票验证系统,被配置为从所述投票解密系统接收解密的投票选择数据和链接信息,以接收投票者选择数据和从所述打印的投票中链接信息,并且比较所述打印和电子投票的样本的选民选择, 链接信息,以验证投票。
    • 2. 发明申请
    • ELECTRONIC VOTING SYSTEMS
    • 电子投票系统
    • WO2005093671A2
    • 2005-10-06
    • PCT/GB2005/000231
    • 2005-01-24
    • CRYPTOMATHIC A/SMARTIN, Philip, JohnSALOMONSEN, GormGROTH, Jens
    • SALOMONSEN, GormGROTH, Jens
    • G07C13/00
    • H04L9/3218G07C13/00H04L2209/463
    • This invention is generally concerned with systems and methods for electronic voting. An electronic voting system, the system comprising: a voting device configured to generate, in response to a voter selection for each of a plurality of voters an encrypted electronic ballot and a printed ballot, both having voter selection data indicating a said voter's choice, said electronic ballot including information to link it to said printed ballot and said printed ballot including information to link it to said electronic ballot; an electronic vote decryption system configured to receive electronic ballots from said voting device and to decrypt said encrypted electronic ballots; including said linking information; and a voting verification system configured to receive decrypted voter selection data and linking information from said vote decryption system, to receive voter selection data and linking information from said printed ballots and to compare voters choices for a sample of said printed and electronic ballots linked by said linking information, to verify the voting.
    • 本发明一般涉及用于电子投票的系统和方法。 一种电子投票系统,该系统包括:投票设备,被配置为响应于多个投票者中的每一个的选民选择产生加密的电子投票和打印投票,两者都具有指示所述投票者的选择的投票者选择数据,所述投票设备 电子投票,包括将其连接到所述打印的投票和所述打印的投票的信息,包括将其链接到所述电子投票的信息; 电子投票解密系统,被配置为从所述投票设备接收电子投票并解密所述加密的电子投票; 包括所述链接信息; 以及投票验证系统,被配置为接收解密的投票选择数据和链接来自所述投票解密系统的信息,接收投票者选择数据和从所述打印的投票中链接信息,并且比较所述打印和电子投票的样本的选民选择, 链接信息,以验证投票。
    • 3. 发明申请
    • COMPOSITIONS OF LOPINAVIR AND RITONAVIR
    • LOPINAVIR和RITONAVIR的组合物
    • WO2013034927A8
    • 2013-04-25
    • PCT/GB2012052210
    • 2012-09-07
    • UNIV LIVERPOOLGIARDIELLO MARCO NORMANMCDONALD THOMAS OLIVEROWEN ANDREWRANNARD STEVEN PAULMARTIN PHILIP JOHNSMITH DARREN LEE
    • GIARDIELLO MARCO NORMANMCDONALD THOMAS OLIVEROWEN ANDREWRANNARD STEVEN PAULMARTIN PHILIP JOHNSMITH DARREN LEE
    • A61K9/19A61K9/51A61K31/536
    • A61K31/427A61K9/19A61K9/5138A61K9/5192A61K31/513A61K38/55A61K2300/00
    • The present inventions relates to a solid composition and an aqueous dispersion comprising nanoparticles of the anti-retroviral drugs lopinavir and ritonavir. The solid composition and aqueous dispersion additionally comprise a mixture of a hydrophilic polymer and a surfactant. The surfactant is selected from vitamin-E-polyethylene glycol- succinate (Vit-E-PEG-succinate), a polyoxyethylene sorbitan fatty acid ester, N- alkyldimethylbenzylammonium chloride, sodium deoxycholate, dioctyl sodium sulfosuccinate, polyethyleneglycol-12-hydroxystearate, polyvinyl alcohol (PVA), and a block copolymer of polyoxyethylene and polyoxypropylene, or a combination thereof. The hydrophilic polymer is suitably selected from polyvinyl alcohol (PVA), a polyvinyl alcohol-polyethylene glycol graft copolymer, a block copolymer of polyoxyethylene and polyoxypropylene, polyethylene glycol, hydroxypropyl methyl cellulose (HPMC), and polyvinylpyrrolidone, or a combination thereof. The present invention also relates to processes for preparing both the solid composition and the aqueous dispersion, as well as to their use in therapy for the treatment and/or prevention of retroviral infections such as human immunodeficiency virus (HIV).
    • 本发明涉及包含抗逆转录病毒药物洛匹那韦和利托那韦的纳米颗粒的固体组合物和水分散体。 固体组合物和水性分散体还包含亲水性聚合物和表面活性剂的混合物。 表面活性剂选自维生素E-聚乙二醇 - 琥珀酸酯(Vit-E-PEG-琥珀酸酯),聚氧乙烯脱水山梨醇脂肪酸酯,N-烷基二甲基苄基氯化铵,脱氧胆酸钠,二辛基磺基琥珀酸钠,聚乙二醇-12-羟基硬脂酸酯,聚乙烯醇 (PVA)和聚氧乙烯和聚氧丙烯的嵌段共聚物,或其组合。 亲水性聚合物适当地选自聚乙烯醇(PVA),聚乙烯醇 - 聚乙二醇接枝共聚物,聚氧乙烯和聚氧丙烯的嵌段共聚物,聚乙二醇,羟丙基甲基纤维素(HPMC)和聚乙烯吡咯烷酮,或其组合。 本发明还涉及制备固体组合物和水性分散体的方法,以及它们在治疗和/或预防逆转录病毒感染如人类免疫缺陷病毒(HIV)中的用途。
    • 4. 发明申请
    • COMPOSITIONS OF EFAVIRENZ
    • EFAVIRENZ的组合物
    • WO2013034925A1
    • 2013-03-14
    • PCT/GB2012/052208
    • 2012-09-07
    • THE UNIVERSITY OF LIVERPOOLGIARDIELLO, Marco NormanMcDONALD, Thomas OliverOWEN, AndrewRANNARD, Steven PaulMARTIN, Philip JohnSMITH, Darren Lee
    • GIARDIELLO, Marco NormanMcDONALD, Thomas OliverOWEN, AndrewRANNARD, Steven PaulMARTIN, Philip JohnSMITH, Darren Lee
    • A61K9/51A61K9/10A61K9/19A61K31/536
    • A61K9/14A61K9/10A61K9/1682A61K9/19A61K9/5138A61K9/5192A61K31/536
    • The present inventions relates to a solid composition and an aqueous dispersion comprising nanoparticles of the anti-retroviral drug efavirenz. The solid composition and aqueous dispersion additionally comprise a mixture of a hydrophilic polymer and a surfactant. The surfactant is selected from vitamin-E-polyethylene glycol-succinate (Vit- E-PEG-succinate), a polyoxyethylene sorbitan fatty acid ester, N-alkyldimethylbenzylammonium chloride, sodium deoxycholate, dioctyl sodium sulfosuccinate, polyethyleneglycol-12-hydroxystearate, polyvinyl alcohol (PVA), and a block copolymer of polyoxyethylene and polyoxypropylene, or a combination thereof. The hydrophilic polymer is suitably selected from polyvinyl alcohol (PVA), a polyvinyl alcohol-polyethylene glycol graft copolymer, a block copolymer of polyoxyethylene and polyoxypropylene, polyethylene glycol, hydroxypropyl methyl cellulose (HPMC), and polyvinylpyrrolidone, or a combination thereof. The present invention also relates to processes for preparing both the solid composition and the aqueous dispersion, as well as to their use in therapy for the treatment and/or prevention of retroviral infections such as human immunodeficiency virus (HIV).
    • 本发明涉及包含抗逆转录病毒药物依法韦仑的纳米颗粒的固体组合物和水性分散体。 固体组合物和水性分散体还包含亲水性聚合物和表面活性剂的混合物。 表面活性剂选自维生素E-聚乙二醇 - 琥珀酸酯(Vit-E-PEG-琥珀酸酯),聚氧乙烯脱水山梨糖醇脂肪酸酯,N-烷基二甲基苄基氯化铵,脱氧胆酸钠,二辛基磺基琥珀酸钠,聚乙二醇-12-羟基硬脂酸酯,聚乙烯醇 (PVA)和聚氧乙烯和聚氧丙烯的嵌段共聚物,或其组合。 亲水性聚合物适当地选自聚乙烯醇(PVA),聚乙烯醇 - 聚乙二醇接枝共聚物,聚氧乙烯和聚氧丙烯的嵌段共聚物,聚乙二醇,羟丙基甲基纤维素(HPMC)和聚乙烯吡咯烷酮,或其组合。 本发明还涉及制备固体组合物和水性分散体的方法,以及它们在治疗和/或预防逆转录病毒感染如人类免疫缺陷病毒(HIV)中的用途。
    • 5. 发明申请
    • IMAGE PROCESSING APPARATUS AND METHODS
    • 图像处理设备和方法
    • WO2004079654A3
    • 2004-10-28
    • PCT/GB2004000988
    • 2004-03-08
    • WEBER MARTINMARTIN PHILIP JOHN
    • WEBER MARTIN
    • G06T5/00
    • G06T7/149G06T7/12G06T2207/20161
    • This invention is generally concerned with image processing systems, and more particularly with improved image processing systems employing a novel numerical scheme for so-called 'level-set' methods to describe moving interfaces. Embodiments of the invention have applications in two, three and higher dimensional modelling, and in particular in fitting a contour or surface to an image or an object. A numerical representation of interfaces (in particular curves and surfaces) is presented which optionally includes so called material properties. Material properties can be used to represent additional non-geometric data on the interface, such as reflectance. A method of processing digital image data representing an image of an object to determine data representing a boundary for said object, the method comprising: inputting said image data; initialising a level set function representation of an interface for approximating said boundary; determining a motion of said interface subject to a combined cost function comprising a first cost comprising a signed distance constraint on said interface level set function representation and a second cost comprising a measure of said interface responsive to a density or metric of said image; modifying said level set function representation of said interface in accordance with said determined motion; repeating said determining and modifying such that said interface converges on said boundary; and determining boundary data representing said boundary from said converged level set function interface representation.
    • 本发明通常涉及图像处理系统,并且更具体地涉及改进的图像处理系统,其采用用于描述移动界面的所谓“水平集”方法的新型数字方案。 本发明的实施例具有二维,三维和更高维建模中的应用,并且特别适用于将轮廓或表面拟合到图像或物体。 介绍界面(特别是曲线和表面)的数字表示,其可选地包括所谓的材料属性。 材料属性可用于表示界面上的其他非几何数据,如反射率。 一种处理表示物体图像的数字图像数据以确定代表所述物体的边界的数据的方法,所述方法包括:输入所述图像数据; 初始化用于逼近所述边界的界面的水平集函数表示; 确定所述接口的运动受制于包括第一成本和第二成本的组合成本函数,所述第一成本包括关于所述界面水平集函数表示的带符号距离约束,所述第二成本包括响应于所述图像的密度或度量的所述接口的度量; 根据所述确定的运动修改所述界面的所述水平集函数表示; 重复所述确定和修改,使得所述界面收敛于所述边界; 以及从所述收敛水平集函数接口表示确定表示所述边界的边界数据。
    • 6. 发明申请
    • COMPOSITIONS OF LOPINAVIR
    • LOPINAVIR的组成
    • WO2013034926A1
    • 2013-03-14
    • PCT/GB2012/052209
    • 2012-09-07
    • THE UNIVERSITY OF LIVERPOOLGIARDIELLO, Marco NormanMcDONALD, Thomas OliverOWEN, AndrewRANNARD, Steven PaulLONG, JamesMARTIN, Philip JohnSMITH, Darren Lee
    • GIARDIELLO, Marco NormanMcDONALD, Thomas OliverOWEN, AndrewRANNARD, Steven PaulLONG, JamesMARTIN, Philip JohnSMITH, Darren Lee
    • A61K9/19A61K9/51A61K31/536
    • A61K9/1682A61K9/14A61K9/19A61K9/5138A61K31/513A61K45/06
    • The present invention relates to a solid composition and an aqueous dispersion comprising nanoparticles of the anti-retroviral drug lopinavir. The solid composition and aqueous dispersion additionally comprise a mixture of a hydrophilic polymer and a surfactant. The surfactant is selected from vitamin-E-polyethylene glycol-succinate (Vit- E-PEG-succinate), a polyoxyethylene sorbitan fatty acid ester, N- alkyldimethylbenzylammonium chloride, sodium deoxycholate, dioctyl sodium sulfosuccinate, polyethyleneglycol-12-hydroxystearate, polyvinyl alcohol (PVA), and a block copolymer of polyoxyethylene and polyoxypropylene, or a combination thereof. The hydrophilic polymer is suitably selected from polyvinyl alcohol (PVA), a polyvinyl alcohol-polyethylene glycol graft copolymer, a block copolymer of polyoxyethylene and polyoxypropylene, polyethylene glycol, hydroxypropyl methyl cellulose (HPMC), and polyvinylpyrrolidone, or a combination thereof. The present invention also relates to processes for preparing both the solid composition and the aqueous dispersion, as well as to their use in therapy for the treatment and/or prevention of retroviral infections such as human immunodeficiency virus (HIV).
    • 本发明涉及包含抗逆转录病毒药物洛匹那韦的纳米颗粒的固体组合物和水分散体。 固体组合物和水分散体另外包含亲水性聚合物和表面活性剂的混合物。 表面活性剂选自维生素E-聚乙二醇 - 琥珀酸酯(Vit-E-PEG-琥珀酸酯),聚氧乙烯脱水山梨糖醇脂肪酸酯,N-烷基二甲基苄基氯化铵,脱氧胆酸钠,二辛基磺基琥珀酸钠,聚乙二醇-12-羟基硬脂酸酯,聚乙烯醇 (PVA)和聚氧乙烯和聚氧丙烯的嵌段共聚物,或其组合。 亲水性聚合物适当地选自聚乙烯醇(PVA),聚乙烯醇 - 聚乙二醇接枝共聚物,聚氧乙烯和聚氧丙烯的嵌段共聚物,聚乙二醇,羟丙基甲基纤维素(HPMC)和聚乙烯吡咯烷酮或其组合。 本发明还涉及制备固体组合物和水性分散体的方法,以及它们在治疗和/或预防逆转录病毒感染如人类免疫缺陷病毒(HIV)中的用途。
    • 7. 发明申请
    • IMAGE PROCESSING APPARATUS AND METHODS
    • 图像处理装置和方法
    • WO2004079654A2
    • 2004-09-16
    • PCT/GB2004/000988
    • 2004-03-08
    • MARTIN, Philip, JohnWEBER, Martin
    • WEBER, Martin
    • G06T5/00
    • G06T7/149G06T7/12G06T2207/20161
    • This invention is generally concerned with image processing systems, and more particularly with improved image processing systems employing a novel numerical scheme for so-called 'level-set' methods to describe moving interfaces. Embodiments of the invention have applications in two, three and higher dimensional modelling, and in particular in fitting a contour or surface to an image or an object. A numerical representation of interfaces (in particular curves and surfaces) is presented which optionally includes so called material properties. Material properties can be used to represent additional non-geometric data on the interface, such as reflectance. A method of processing digital image data representing an image of an object to determine data representing a boundary for said object, the method comprising: inputting said image data; initialising a level set function representation of an interface for approximating said boundary; determining a motion of said interface subject to a combined cost function comprising a first cost comprising a signed distance constraint on said interface level set function representation and a second cost comprising a measure of said interface responsive to a density or metric of said image; modifying said level set function representation of said interface in accordance with said determined motion; repeating said determining and modifying such that said interface converges on said boundary; and determining boundary data representing said boundary from said converged level set function interface representation.
    • 本发明通常涉及图像处理系统,更具体地涉及采用用于所谓的“级别集”方法来描述移动界面的新型数值方案的改进的图像处理系统。 本发明的实施例在二维,三维和更高维度建模中具有应用,并且特别地将轮廓或表面拟合到图像或对象。 提出了界面(特别是曲线和曲面)的数值表示,其可选地包括所谓的材料属性。 材料属性可用于表示界面上的其他非几何数据,如反射率。 一种处理表示对象的图像的数字图像数据的方法,用于确定表示所述对象的边界的数据,所述方法包括:输入所述图像数据; 初始化用于近似所述边界的接口的级集合函数表示; 根据组合成本函数确定所述接口的运动,所述组合成本函数包括第一成本,所述第一成本包括对所述接口级集合函数表示的有符号距离约束,以及响应于所述图像的密度或度量的所述接口的度量的第二成本; 根据所述确定的运动修改所述接口的所述电平集函数表示; 重复所述确定和修改使得所述接口收敛在所述边界上; 以及从所述会聚级集合函数接口表示确定表示所述边界的边界数据。