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1. 发明申请

WO2007118194A3 RESONANCE CIRCUIT FOR IMPLANTABLE DEVICES AND LEADS 审中-公开
标题翻译：用于可移植设备和引线的谐振电路
公开(公告)号：WO2007118194A3
公开(公告)日：2008-08-07
申请号：PCT/US2007066143
申请日：2007-04-06
申请人： BIOPHAN TECHNOLOGIES INC , GRAY ROBERT W , MACDONALD STUART G
发明人： GRAY ROBERT W , MACDONALD STUART G
IPC分类号： A61N1/00
CPC分类号： A61N1/36125 , A61N1/056 , A61N1/086
摘要： An implantable medical assist device includes a housing and electronics contained therein. A lead provides an electrical path to or from the electronics. A resonance tuning module is located in the housing and is connected to the lead. The resonance tuning module includes a control circuit for determining a resonant frequency of the implantable medical assist device and an adjustable impedance circuit to change the combined resonant frequency of the medical device and lead. Also, a stent structure includes a stent formed of a plurality of rings to form a lumen and a plurality of struts. The stent structure also includes a conductive trace and a dielectric material. The first end of the conductive trace overlaps the second end of the conductive trace such that the dielectric material is located between the first end of the conductive trace and the second end of the conductive trace to form a capacitor.
摘要翻译：可植入医疗辅助装置包括其中包含的壳体和电子装置。引线提供到电子设备的电路。谐振调谐模块位于壳体中并连接到引线。谐振调谐模块包括用于确定可植入医疗辅助装置的谐振频率的控制电路和用于改变医疗装置和引线的组合谐振频率的可调阻抗电路。此外，支架结构包括由多个环形成的支架，以形成内腔和多个支柱。支架结构还包括导电迹线和电介质材料。导电迹线的第一端与导电迹线的第二端重叠，使得介电材料位于导电迹线的第一端和导电迹线的第二端之间以形成电容器。

2. 发明申请

WO2008076956A2 MEDICAL LEADS WITH FREQUENCY INDEPENDENT MAGNETIC RESONANCE IMAGING PROTECTION 审中-公开
标题翻译：具有频率独立磁共振成像保护的医疗引线
公开(公告)号：WO2008076956A2
公开(公告)日：2008-06-26
申请号：PCT/US2007087710
申请日：2007-12-17
申请人： MEDTRONIC INC , MACDONALD STUART G , SMITH LON E , GRAY ROBERT W , WEINER MICHAEL L
发明人： MACDONALD STUART G , SMITH LON E , GRAY ROBERT W , WEINER MICHAEL L
IPC分类号： A61N1/00
CPC分类号： A61N1/37 , A61N1/086 , A61N1/3718 , H03H1/0007
摘要： A medical device having a diode configuration in a lead assembly that substantially reduces induced currents in a lead assembly and at a tissue interface. The diodes configure an electrical path such that a stimulation pulse travels from the medical device to a selected tissue, and a current induced by an external changing electromagnetic signal is reduced and/or prevented from travelling the electrical path from the selected tissue to the medical device. The diodes may be at least partially contained in an electrode of the medical device.
摘要翻译：一种在引线组件中具有二极管配置的医疗设备，其基本上减少了引线组件和组织界面处的感应电流。二极管配置电路，使得刺激脉冲从医疗装置传播到选定的组织，并且由外部变化的电磁信号感应的电流减少和/或阻止从所选择的组织到医疗装置的电路传播。二极管可以至少部分地包含在医疗装置的电极中。

3. 发明申请

WO2006093675A3 PROCESS AND APPARATUS FOR TREATING BIOLOGICAL ORGANISMS 审中-公开
公开(公告)号：WO2006093675A3
公开(公告)日：2006-09-08
申请号：PCT/US2006/005415
申请日：2006-02-16
申请人： BIOMED SOLUTIONS, LLC , WEINER, Michael, L. , GRAY, Robert, W. , MACDONALD, Stuart, G. , TUSZYNSKI, Jack, A. , GOSS, Kendrick , ANGELICA, Amara, D.
发明人： WEINER, Michael, L. , GRAY, Robert, W. , MACDONALD, Stuart, G. , TUSZYNSKI, Jack, A. , GOSS, Kendrick , ANGELICA, Amara, D.
IPC分类号： A61N5/10 , G21K5/00 , G01N23/00
摘要： An apparatus for treating a biological organism comprising a device for emitting and delivering energy to the biological organism, a programmable controller for varying the type and amount of energy emitted, and apparatus for sensing a condition of the biological organism.

4. 发明申请

WO2006031395A1 BIOTHERMAL POWER SOURCE FOR IMPLANTABLE DEVICES 审中-公开
标题翻译：用于可植入器件的双电源
公开(公告)号：WO2006031395A1
公开(公告)日：2006-03-23
申请号：PCT/US2005/030023
申请日：2005-08-23
申请人： BIOMED SOLUTIONS, LLC , MACDONALD, Stuart, G.
发明人： MACDONALD, Stuart, G.
IPC分类号： A61N1/08
CPC分类号： H01L35/00 , A61N1/08 , A61N1/3708 , A61N1/3718 , A61N1/3785 , H01M10/42
摘要： An implantable, rechargeable assembly comprised of an implantable device disposed within a living organism, an electrical storage device connected to the implantable device, and a thermoelectric charging assembly operatively connected to the electrical storage device. The thermoelectric charging assembly has devices for transferring thermal energy between the living organism and a thermoelectric module, for generating an electrical current from the thermal energy, for charging the electrical storage device with the electrical current, for determining the extent to which the electrical storage device is being charged with the electrical storage device is being charged with the electrical current falls below a specified value.
摘要翻译：一种可植入的可充电组件，包括设置在活体内的可植入装置，连接到可植入装置的电存储装置以及可操作地连接到蓄电装置的热电充电组件。热电充电组件具有用于在活体和热电模块之间传递热能的装置，用于从热能产生电流，用于用电流对蓄电装置充电，以确定蓄电装置的程度正在充电时，蓄电装置正在充电，电流下降到指定值以下。

5. 发明申请

WO2005117512A1 MAGNETICALLY SHIELDED ASSEMBLY 审中-公开
标题翻译： MAGNETICALLY被屏蔽的装配
公开(公告)号：WO2005117512A1
公开(公告)日：2005-12-08
申请号：PCT/US2005/010194
申请日：2005-03-25
申请人： NANOSET, LLC , WANG, Xingwu , HELFER, Jeffrey, L. , MACDONALD, Stuart, G.
发明人： WANG, Xingwu , HELFER, Jeffrey, L. , MACDONALD, Stuart, G.
IPC分类号： H05K9/00
CPC分类号： H05K9/0075 , A61N1/16 , B82Y25/00 , H01B11/10 , H01B11/1083 , H01F1/0063 , H01F10/007 , H01F10/324
摘要： A shielded assembly containing a substrate and a shield. The shield contains both nonmagnetic material and a material with an electrical resistivity of from about 1 microohm-centimeter to about 1 x 10 25 microohm centimeters. The nanomagnetic material has a mass density of at least about 0.01 grams per cubic centimeter, a saturation magnetization of from about 1 to about 36,000 Gauss, a coercive force of from about 0.01 to about 5000 Oersteds, a relative magnetic permeability of from about 1 to about 500,000, and an average particle size of less than about 100 nanometers.
摘要翻译：包含基板和屏蔽的屏蔽组件。屏蔽件包含非磁性材料和电阻率为约1微欧姆至约1×10 25微欧姆厘米的材料。纳米磁性材料的质量密度为至少约0.01克/立方厘米，饱和磁化强度为约1至约36,000高斯，矫顽力为约0.01至约5000奥斯特，相对磁导率为约1至约500,000，平均粒径小于约100纳米。

6. 发明申请

WO2005091860A2 METHOD AND APPARATUS FOR DIRECT MECHANICAL VENTRICULAR ACTUATION WITH FAVORABLE CONDITIONING AND MINIMAL HEART STRESS 审中-公开
标题翻译：用于直接机械通气的方法和装置，具有良好的调节和最小的心脏应激
公开(公告)号：WO2005091860A2
公开(公告)日：2005-10-06
申请号：PCT/US2005/005497
申请日：2005-02-22
申请人： ADVANCED RESUSCITATION, LLC. , ANSTADT, Mark, P. , ANSTADT, George, L. , MACDONALD, Stuart, G. , HELFER, Jeffrey, L. , ANSTADT, George, W.
发明人： ANSTADT, Mark, P. , ANSTADT, George, L. , MACDONALD, Stuart, G. , HELFER, Jeffrey, L. , ANSTADT, George, W.
IPC分类号： A61M1/10 , A61M1/12 , A61N1/05 , A61N1/362 , A61N1/368
CPC分类号： A61N1/0587 , A61M1/106 , A61M1/1068 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/33 , A61M2205/3303 , A61N1/0597 , A61N1/3627 , A61N1/3684
摘要： A process for assisting the function of a heart disposed within a body, comprising, the steps of supporting the heart in providing circulation of blood for perfusion of an organ in the body, remodeling the heart to render the heart in an improved state, and stabilizing the heart in the improved state. The process is preferably performed with an apparatus comprising a cup-shaped shell having an exterior surface and an interior surface; a liner having an outer surface, an upper edge joined to said interior surface of said cup-shaped shell, and a lower edge joined of said interior surface of said cup-shaped shell, thereby forming a cavity between said outer surface thereof and said interior surface of said shell; a drive fluid cyclically interposed within said cavity; and at least one sensor measuring at least one macroscopic parameter indicative of said function of said heart. Further embodiments of the process and apparatus include means and use thereof for delivering a therapeutic agent to the heart.
摘要翻译：一种用于辅助设置在体内的心脏的功能的过程，包括以下步骤：支撑心脏以提供血液循环以灌注身体内的器官，重建心脏以使心脏处于改善的状态，以及稳定心脏在改善状态。该方法优选用包括具有外表面和内表面的杯形壳体的装置进行; 具有外表面的衬垫，连接到所述杯形壳体的所述内表面的上边缘以及所述杯状壳体的所述内表面连接的下边缘，从而在其外表面和所述内部之间形成空腔所述外壳的表面; 循环地插入所述空腔内的驱动流体; 以及至少一个传感器，其测量指示所述心脏的所述功能的至少一个宏观参数。该方法和装置的其它实施方案包括将治疗剂递送至心脏的手段和用途。

7. 发明申请

WO2003101534A1 NUCLEAR MAGNETIC RESONANCE SPECTROMETER ASSEMBLY 审中-公开
标题翻译：核磁共振光谱仪组件
公开(公告)号：WO2003101534A1
公开(公告)日：2003-12-11
申请号：PCT/US2003/017610
申请日：2003-06-04
申请人： BIOPHAN TECHNOLOGIES, INC. , HELFER, Jeffrey, L. , WEINER, Michael, L. , CONNELLY, Patrick, R. , MAcDONALD, Stuart, G.
发明人： HELFER, Jeffrey, L. , WEINER, Michael, L. , CONNELLY, Patrick, R. , MAcDONALD, Stuart, G.
IPC分类号： A61N1/18
CPC分类号： A61N1/37 , A61B5/0215 , A61B5/055 , A61B5/14532 , A61B5/14546 , A61B5/1459 , A61B5/7203 , A61B2562/02 , A61B2562/0233 , A61B2562/046 , A61B2562/222 , A61B2562/223 , A61N1/3718 , G01R33/285
摘要： An implantable nuclear magnetic resonance spectrometer comprised of a first input lead and a second output lead, wherein each of said first input lead and said second output lead comprise a photonic lead (585).
摘要翻译：一种可植入核磁共振光谱仪，包括第一输入引线和第二输出引线，其中所述第一输入引线和所述第二输出引线中的每一个包括光子引线（585）。

8. 发明申请

WO2003011386A1 FLOW CYTOMETER 审中-公开
标题翻译：流量计
公开(公告)号：WO2003011386A1
公开(公告)日：2003-02-13
申请号：PCT/US2002/023892
申请日：2002-07-29
申请人： BIOMED SOLUTIONS, LLC , CONNELLY, Patrick, R. , MACDONALD, Stuart, G. , GRAY, Robert, W. , GEBERT, Carol
发明人： CONNELLY, Patrick, R. , MACDONALD, Stuart, G. , GRAY, Robert, W. , GEBERT, Carol
IPC分类号： A61M37/00
CPC分类号： A61B5/0084 , A61B5/0071 , A61B5/076 , A61B5/145 , A61B5/150015 , A61B5/150221 , A61B5/150229 , A61B5/417 , A61F2/82 , A61M1/3621 , A61M1/3679 , A61M1/3687 , A61M1/38 , G01N15/10 , G01N2015/1006 , G01N2015/149
摘要： A flow cytometer (44) containing a device for sampling cellular material within a body, comprising a detector (86), controller (88), light source (84) and injector (96). The flow cytometer (44) is adapted to mark cells within bodily fluid with a marker to produce marked cells, to analyze the marked cells, to sort the cells within the bodily fluid to produce sorted cells, and to maintain the sorted cells in a viable state.
摘要翻译：一种流式细胞仪（44），其包含用于在体内采样细胞材料的装置，包括检测器（86），控制器（88），光源（84）和注射器（96）。流式细胞仪（44）适于用标记物标记体液中的细胞以产生标记的细胞，分析标记的细胞，对体液内的细胞进行分类以产生分选的细胞，并将分选的细胞维持在可行的州。

9. 发明申请

WO2003011385A1 FLOW CYTOMETER SHUNT 审中-公开
标题翻译：流量计流量计
公开(公告)号：WO2003011385A1
公开(公告)日：2003-02-13
申请号：PCT/US2002/023780
申请日：2002-07-29
申请人： BIOMED SOLUTIONS, LLC , CONNELLY, Patrick, R. , MACDONALD, Stuart, G. , GRAY, Robert, W. , GEBERT, Carol
发明人： CONNELLY, Patrick, R. , MACDONALD, Stuart, G. , GRAY, Robert, W. , GEBERT, Carol
IPC分类号： A61M37/00
CPC分类号： A61B5/0084 , A61B5/0071 , A61B5/076 , A61B5/145 , A61B5/15003 , A61B5/155 , A61F2/82 , A61M1/3621 , A61M1/3679 , A61M1/3687 , A61M1/38 , G01N15/1456 , G01N2015/1006 , G01N2015/149
摘要： A flow cytometer (300) containing a device for sampling cellular material (306) within a body. The flow cytometer is adapted to mark cells within bodily fluid (306) with a marker to produce marked cells, to analyze the marked cells, to sort the cells within the bodily fluid to produce sorted cells, to maintain the sorted cells in a viable state, and to remove the marker from the marked cells. Two marker removal devices (320, 324) are used in the flow cytometer.
摘要翻译：流式细胞仪（300），其包含用于在体内采样细胞材料（306）的装置。流式细胞仪适于用标记物标记体液（306）中的细胞以产生标记的细胞，分析标记的细胞，对体液内的细胞进行分类以产生分选的细胞，以将分选的细胞维持在可行状态并从标记的细胞中去除标记物。在流式细胞仪中使用两个标记物去除装置（320,324）。

10. 发明申请

WO2007062239A2 METHOD AND APPARATUS FOR MINIMALLY INVASIVE DIRECT MECHANICAL VENTRICULAR ACTUATION 审中-公开
标题翻译：最小直接机械通气动作的方法与装置
公开(公告)号：WO2007062239A2
公开(公告)日：2007-05-31
申请号：PCT/US2006/045492
申请日：2006-11-28
申请人： MYOTECH LLC , MACDONALD, Stuart G. , PEREZ-TAMAYO, Ruheri A. , ANSTADT, George W.
发明人： MACDONALD, Stuart G. , PEREZ-TAMAYO, Ruheri A. , ANSTADT, George W.
IPC分类号： A61F2/02
CPC分类号： A61M1/122 , A61F2/2481 , A61F2002/2484 , A61F2250/0003 , A61M1/1008 , A61M1/1058 , A61M1/106 , A61M1/1068 , A61M1/12 , A61M2205/0283
摘要： A device for assisting the function of a heart can be deployed using minimally invasive procedures. The device is collapsible to facilitate insertion into the chest cavity and deployment on the heart, e.g., via a specially configured tube. In one embodiment, the device includes a cup-shaped shell having a wall with an outer surface and an inner surface, the wall extending from a hole at an apex of the shell to a rim; a cup-shaped support cage disposed within the cup-shaped shell, the support cage comprising a base comprising a port and a plurality of flexible radial struts comprising proximal ends extending from the base contiguously along the inner surface of the shell to distal ends that are proximate to the rim of the shell; a liner comprising an outer surface, an inner surface, an upper region joined to the rim of the cup-shaped shell, a tapered seal, an elastic central region, and a lower region joined to the cup-shaped shell proximate to the base of the support cage, thereby forming an inflatable cavity between the outer surface of the liner and the inner surface of the shell; a first fitting connected to the apex of the cup-shaped shell and connectable to a first lumen; and; and a second fitting in communication with the inflatable cavity between the outer surface of the liner and the inner surface of the shell and connectable to a second lumen.
摘要翻译：可以使用微创程序部署用于辅助心脏功能的装置。该装置可折叠以便于插入胸腔并且例如通过特别配置的管部署在心脏上。在一个实施例中，该装置包括具有外壁和内表面的壁的杯形壳，该壁从壳的顶点处的孔延伸到边缘; 设置在杯形壳体内的杯状支撑保持架，支撑架包括底座，该基座包括端口和多个柔性径向支柱，该基座包括从底座沿着壳体的内表面连续延伸到远端的近端，靠近壳的边缘; 衬套，其包括外表面，内表面，连接到杯形壳的边缘的上部区域，锥形密封件，弹性中心区域和连接到杯形壳体的下部区域，靠近基座从而在衬套的外表面和壳的内表面之间形成可膨胀的空腔; 连接到杯形壳体的顶点并可连接到第一管腔的第一配件; 和; 以及第二配件，其与所述衬套的外表面和所述壳体的内表面之间的所述可充气腔连通，并且可连接到第二内腔。

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