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1. 发明申请

WO2008030284A3 SOFT MEMS 审中-公开
标题翻译：软MEMS
公开(公告)号：WO2008030284A3
公开(公告)日：2008-06-26
申请号：PCT/US2007012987
申请日：2007-06-01
申请人： UNIV ILLINOIS , LIU CHANG , ENGEL JONATHAN , CHEN NANNAN , RYU KEE , LIU CHANG , TUCKER CRAIG , YANG YINGCHEN
发明人： LIU CHANG , ENGEL JONATHAN , CHEN NANNAN , RYU KEE , LIU CHANG , TUCKER CRAIG , YANG YINGCHEN
IPC分类号： B32B7/02 , B81C99/00
CPC分类号： B01L3/502707 , B01L2200/12 , B01L2300/0645 , B01L2300/0887 , B01L2300/1827 , B81C99/0095 , B82Y10/00 , H01L51/0595
摘要： A microscale polymer-based apparatus comprises a substrate formed from a first polymer material and at least one active region integrated with the substrate. The at least one active region is patterned from a second polymer material that is modified to perform at least one function within the at least one active region.
摘要翻译：基于微量聚合物的设备包括由第一聚合物材料形成的基底和与基底成一体的至少一个有源区。所述至少一个活性区域从被修饰以在所述至少一个活性区域内执行至少一个功能的第二聚合物材料图案化。

2. 发明申请

WO2008030284A2 SOFT MEMS 审中-公开
标题翻译：软MEMS
公开(公告)号：WO2008030284A2
公开(公告)日：2008-03-13
申请号：PCT/US2007/012987
申请日：2007-06-01
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , LIU, Chang , ENGEL, Jonathan , CHEN, Nannan , RYU, Kee , LIU, Chang , TUCKER, Craig , YANG, Yingchen
发明人： LIU, Chang , ENGEL, Jonathan , CHEN, Nannan , RYU, Kee , LIU, Chang , TUCKER, Craig , YANG, Yingchen
IPC分类号： G11C17/00
CPC分类号： B01L3/502707 , B01L2200/12 , B01L2300/0645 , B01L2300/0887 , B01L2300/1827 , B81C99/0095 , B82Y10/00 , H01L51/0595
摘要： A microscale polymer-based apparatus comprises a substrate formed from a first polymer material and at least one active region integrated with the substrate. The at least one active region is patterned from a second polymer material that is modified to perform at least one function within the at least one active region.
摘要翻译：基于微型聚合物的装置包括由第一聚合物材料形成的基板和与基板结合的至少一个有源区。所述至少一个有源区域由第二聚合物材料图案化，所述第二聚合物材料被修改以在所述至少一个有源区域内执行至少一个功能。

3. 发明申请

WO2020056152A1 SINGLE CHAIN CONSTRUCTS 审中-公开
公开(公告)号：WO2020056152A1
公开(公告)日：2020-03-19
申请号：PCT/US2019/050837
申请日：2019-09-12
申请人： LIU, Chang , FREMONT, Daved, H. , EDELSON, Brian , NELSON, Christopher, A. , WANG, Xiaoli
发明人： LIU, Chang , FREMONT, Daved, H. , EDELSON, Brian , NELSON, Christopher, A. , WANG, Xiaoli
IPC分类号： A61K38/00 , C07K14/74 , C07K19/00 , C12N15/12
摘要： Fusion proteins are provided, the fusion proteins comprising a single-chain trimer coupled to an Fc domain of an antibody. Also provided are methods of use thereof.

4. 发明申请

WO2010096602A1 OCCLUSION DETECTION SYSTEM 审中-公开
标题翻译： OCCLUSION检测系统
公开(公告)号：WO2010096602A1
公开(公告)日：2010-08-26
申请号：PCT/US2010/024645
申请日：2010-02-19
申请人： HOSPIRA, INC. , WANG, YiFei , LIU, Chang , NG, See Hai
发明人： WANG, YiFei , LIU, Chang , NG, See Hai
IPC分类号： G01M3/02 , A61M1/00
CPC分类号： A61M5/1456 , A61M5/16854 , A61M2005/16863 , A61M2205/18 , A61M2205/332
摘要： A method of monitoring pressure inside a fluid line and a system for implementing the method. The method is applicable to syringe pump systems. The method includes the steps of measuring a force value caused by a pressure inside the fluid line; collecting the measured force values during at least two consecutive moving time windows; calculating a slope of a best-fit line within each time window; calculating a slope difference of the slopes of the best-fit lines; comparing the slope difference with a pre-determined threshold gradient value; defining a baseline force as the detected force value when the slope difference is equal to the threshold gradient value; determining a relative force value by subtracting the baseline force from the detected force value; and, triggering an alarm if the relative force is greater than a pre-defined threshold force
摘要翻译：一种监测流体管线内压力的方法和一种用于实施该方法的系统。该方法适用于注射泵系统。该方法包括以下步骤：测量由流体管线内的压力引起的力值; 在至少两个连续移动时间窗口期间收集测量的力值; 计算每个时间窗内最佳拟合线的斜率; 计算最佳拟合线的斜率的斜率差; 将斜率差与预定阈值梯度值进行比较; 当所述斜率差等于所述阈值梯度值时，将基线力定义为所述检测到的力值; 通过从检测到的力值减去基准力来确定相对力值; 并且如果相对力大于预定义的阈值力，则触发报警

5. 发明申请

WO2007126739A3 SAFETY CIRCUIT FOR ELECTRO-LUMINESCENT LAMP BALLAST 审中-公开
标题翻译：电子灯泡安全电路
公开(公告)号：WO2007126739A3
公开(公告)日：2008-10-23
申请号：PCT/US2007007417
申请日：2007-03-26
申请人： CEELITE LLC , LIANG CHIN-PING , LIU CHANG-YI
发明人： LIANG CHIN-PING , LIU CHANG-YI
IPC分类号： H05B37/02
CPC分类号： H05B33/08 , H05B41/2851 , Y02B20/325 , Y10S315/07
摘要： A safety circuit is provided for a ballast (11) of an electro-luminescent (EL) lamp (12). The EL lamp had an electrical ground shield (17) on at least a portion thereof and has a separate ground lead (18). The ballast is an isolated ballast with a line input being isolated from an output. The ballast is constructed and arranged to be electrically connected with the separate ground lead. The circuit includes a current sensing structure (20) constructed and arranged to connect between the separate ground lead and a potential ground of the ballast. In the event a user contacts the EL lamp to replace the EL lamp or contacts a defective EL lamp, the ballast is shut down based on a value of current sensed by the current sensing structure.
摘要翻译：为电致发光（EL）灯（12）的镇流器（11）提供安全电路。 EL灯在其至少一部分上具有电接地屏蔽（17），并具有单独的接地引线（18）。镇流器是隔离的镇流器，线路输入与输出隔离。镇流器被构造和布置成与单独的接地引线电连接。电路包括电流感测结构（20），其构造和布置成在分离的地线和镇流器的潜在地之间连接。在用户接触EL灯以更换EL灯或接触有缺陷的EL灯的情况下，镇流器基于由电流感测结构感测的电流值而关闭。

6. 发明申请

WO2007143123A2 MICROMACHINED ARTIFICIAL HAIRCELL 审中-公开
标题翻译： MICROMACHINED人造毛发
公开(公告)号：WO2007143123A2
公开(公告)日：2007-12-13
申请号：PCT/US2007/012991
申请日：2007-06-01
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , LIU, Chang , ENGEL, Jonathan , CHEN, Nannan , CHEN, Jack
发明人： LIU, Chang , ENGEL, Jonathan , CHEN, Nannan , CHEN, Jack
IPC分类号： G01P15/12
CPC分类号： G01P15/123 , B81B3/0021 , B81B2201/0292 , B81B2203/0118 , G01P5/04 , G01P15/0802
摘要： A micromachined artificial sensor comprises a support coupled to and movable with respect to a substrate. A polymer, high-aspect ratio cilia-like structure is disposed on and extends out-of-plane from the support. A strain detector is disposed with respect to the support to detect movement of the support.
摘要翻译：微加工人造传感器包括耦合到基板并且可相对于基板移动的支撑件。聚合物，高纵横比的纤毛状结构从载体上设置在平面外并从其延伸。应变检测器相对于支撑件设置以检测支撑件的运动。

7. 发明申请

WO2005078139A2 DIAGNOSIS AND TREATMENT OF CANCERS WITH MicroRNA LOCATED IN OR NEAR CANCER-ASSOCIATED CHROMOSOMAL FEATURES 审中-公开
标题翻译：诊断和治疗位于或接近癌相关染色体特征的微小RNA
公开(公告)号：WO2005078139A2
公开(公告)日：2005-08-25
申请号：PCT/US2005/004865
申请日：2005-02-09
申请人： THOMAS JEFFERSON UNIVERSITY , CROCE, Carlo, M. , LIU, Chang-Gong , CALIN, George, A.
发明人： CROCE, Carlo, M. , LIU, Chang-Gong , CALIN, George, A.
IPC分类号： C12Q1/68
CPC分类号： C12N15/1135 , A61K31/7088 , A61K31/713 , A61K45/06 , C12N7/00 , C12N15/113 , C12N2310/11 , C12N2310/141 , C12N2310/31 , C12N2310/32 , C12N2310/33 , C12N2710/16143 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , C12Q2600/178
摘要： MicroRNA genes are highly associated with chromosomal features involved in the etiology of different cancers. The perturbations in the genomic structure or chromosomal architecture of a cell caused by these cancer-associated chromosomal features can affect the expression of the miR genes) located in close proximity to that chromosomal feature. Evaluation of miR gene expression can therefore be used to indicate the presence of a cancercausing chromosomal lesion in a subject. As the change in miR gene expression level caused by a cancer-associated chromosomal feature may also contribute to cancerigenesis, a given cancer fan be treated by restoring the level of miR gene expression to normal.
摘要翻译： MicroRNA基因与涉及不同癌症病因的染色体特征高度相关。由这些与癌症相关的染色体特征引起的细胞的基因组结构或染色体结构的扰动可影响位于该染色体特征附近的miR基因的表达。因此，miR基因表达的评估可用于指示受试者中存在癌症染色体损伤。由于由癌症相关的染色体特征引起的miR基因表达水平的变化也可能导致癌发生，通过将miR基因表达水平恢复至正常来治疗给定的癌症风扇。

8. 发明申请

WO2004024079A8 METHODS AND COMPOSITIONS FOR PRODUCTION OF FLAVONOID AND ISOFLAVONOID NUTRACEUTICALS 审中-公开
标题翻译：用于生产黄酮类和异黄酮类营养品的方法和组合物
公开(公告)号：WO2004024079A8
公开(公告)日：2005-03-17
申请号：PCT/US0328454
申请日：2003-09-10
申请人： SAMUEL ROBERTS NOBLE FOUND INC , DIXON RICHARD A , LIU CHANG-JUN , DEAVOURS BETTINA
发明人： DIXON RICHARD A , LIU CHANG-JUN , DEAVOURS BETTINA
IPC分类号： A01H1/00 , C12N9/02 , C12N9/90 , C12N15/82 , A61K
CPC分类号： C12N9/0071 , C12N9/0077 , C12N15/8243 , C12N15/825
摘要： The invention provides method and compositions for the modulation of flavanone and/or isoflavone production in plants. The methods of the invention allow creation of plants having novel phenotypes. Increased expression of isoflavones in particular in plants may be used to increase the nutritional value of food plants for both human and animal consumption. The invention overcomes limitations of the prior art which prevented accumulation of high levels of isoflavones in plants.
摘要翻译：本发明提供了用于调节植物中黄烷酮和/或异黄酮产生的方法和组合物。本发明的方法允许产生具有新表型的植物。异黄酮在植物中的表达增加可用于增加食用植物对人类和动物消费的营养价值。本发明克服了防止植物中高水平异黄酮积累的现有技术的限制。

9. 发明申请

WO2021242177A1 USER-FACING SPREADSHEET PROGRAMMING LANGUAGE 审中-公开
公开(公告)号：WO2021242177A1
公开(公告)日：2021-12-02
申请号：PCT/SG2021/050299
申请日：2021-05-31
申请人： LIU, Chang
发明人： LIU, Chang
IPC分类号： G06F8/34
摘要： Spreadsheets and methods for programming spreadsheets are provided. In accordance with one aspect. The spreadsheet includes a plurality of cells arranged in a two-dimensional array. One or more of the plurality of cells include a plurality of adjoining variable value cells for data corresponding to a plurality of values of a variable. The plurality of adjoining variable value cells are user defined by a pair of cell values indicating a start and an end of a cell range of the plurality of adjoining variable value cells. The plurality of cells also include a spill area into which data can flow from a cell having an expression defined therein in response to the expression including a variable range defined by the plurality of values of the variable. The spill area is automatically sized to a plurality of expression solutions corresponding to the plurality of values of the variable.

10. 发明申请

WO2015187225A2 ULTRASENSITIVE SOLUTION-PROCESSED PEROVSKITE HYBRID PHOTODETECTORS 审中-公开
标题翻译：超声波解决方案处理的PEROVSKITE混合光电转换器
公开(公告)号：WO2015187225A2
公开(公告)日：2015-12-10
申请号：PCT/US2015/020286
申请日：2015-03-12
申请人： THE UNIVERSITY OF AKRON , GONG, Xiong , WANG, Kai , LIU, Chang
发明人： GONG, Xiong , WANG, Kai , LIU, Chang
IPC分类号： H01L31/0256
CPC分类号： H01L51/0077 , H01L31/0256 , H01L31/032 , H01L51/0032 , H01L51/0036 , H01L51/0037 , H01L51/0047 , H01L51/4226 , H01L51/442 , H01L2031/0344 , H01L2251/308 , Y02E10/549 , Y02P70/521
摘要： A photodetector includes an active layer formed of an inorganic/organic hybrid perovskite material, such as organometal halide perovskites. The perovskite hybrid photodetector provides low dark-current densities and high external-quantum efficiencies, resulting in a photodetector with enhanced photoresponsivity and detectivity. Advantageously, the perovskite hybrid photodetector may be prepared by solution processing, and is compatible with large-scale manufacturing techniques.
摘要翻译：光电检测器包括由无机/有机杂化钙钛矿材料如有机金属卤化物钙钛矿形成的活性层。钙钛矿混合光电探测器提供低的暗电流密度和高的外部量子效率，导致具有增强的光响应性和检测性的光电探测器。有利地，钙钛矿型混合光电检测器可以通过溶液处理制备，并且与大规模制造技术相容。

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