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    • 3. 发明申请
    • WATER-BASED ANTIMICROBIALLY ACTIVE, DISPERSION CONCENTRATES
    • 基于水的抗微生物活性,分散浓度
    • WO2008136917A1
    • 2008-11-13
    • PCT/US2008/005154
    • 2008-04-22
    • TROY TECHNOLOGY CORPORATION, INC.BUSSMANN, WernerROESSLER, BurkhardLINDNER, Wolfgang
    • BUSSMANN, WernerROESSLER, BurkhardLINDNER, Wolfgang
    • A01N25/00
    • A01N25/04A01N25/30A01N43/40A01N43/707A01N43/80A01N47/12A01N47/30
    • Highly concentrated, water-based dispersions of certain lipophilic and/or hydrophobic antimicrobially active materials are stabilized to a surprising degree by a surfactant combination including a nonionic acrylic graft copolymer surfactant and a alkoxylated polyarylphenol phosphate ester surfactant. The active materials may be present in dispersion concentrates of the present invention singly or in useful combinations. The active materials are selected from the group of fungicides and bactericides consisting of l,2-benzisothiazol-3(2H)-one; 2-octyl-2H-isothiazol-3-one; 5- chloro-2-methyl-2H-isothiazol-3-one; 2-methyl-2H-isothiazol-3-one; pyrithione zinc; 3- iodo-2-propynyl butylcarbamate; 2-methylthio-4-ethylamino-6-tert-butylamino-s- triazine; and 3-(4-isopropylphenyl)-l,l-dimethylurea, and mixtures thereof. The dispersion concentrates may be efficiently shipped and stored, and subsequently diluted with water to produce less concentrated dispersions when desired. Even at relatively high concentrations, the dispersion compositions of the present invention can be stored for months or years without significant loss of stability.
    • 通过包括非离子丙烯酸接枝共聚物表面活性剂和烷氧基化聚芳基酚磷酸酯表面活性剂的表面活性剂组合将某些亲油和/或疏水性抗微生物活性材料的高度浓缩的水基分散体稳定到惊人的程度。 活性物质可以单独存在或以有用的组合存在于本发明的分散体浓缩物中。 活性物质选自由1,2-苯并异噻唑-3(2H) - 酮组成的杀真菌剂和杀菌剂; 2-辛基-2H-异噻唑-3-酮; 5-氯-2-甲基-2H-异噻唑-3-酮; 2-甲基-2H-异噻唑-3-酮; 吡啶硫酮锌 3-碘-2-丙炔基丁基氨基甲酸酯; 2-甲硫基-4-乙基氨基-6-叔丁基氨基-s-三嗪; 和3-(4-异丙基苯基)-1,1-二甲基脲及其混合物。 分散浓缩物可以有效地运输和储存,然后在需要时用水稀释以产生较少浓度的分散体。 即使在相对高的浓度下,本发明的分散体组合物也可以保存数月或数年,而不会明显地损失稳定性。
    • 4. 发明申请
    • IMMOBILIZED 1,2-BENZISOTHIAZOLIN-3-ONE
    • 固定化1,2-苯并异噻唑啉-3-酮
    • WO2007139645A3
    • 2008-09-12
    • PCT/US2007010124
    • 2007-04-20
    • TROY TECHNOLOGY CORP INCLINDNER WOLFGANG
    • LINDNER WOLFGANG
    • C07D275/04
    • C07F3/003A61K31/555C07B2200/11
    • The present invention provides novel antimicrobial immobilized 1,2- benzisothiazolin-3-one/zinc oxide (BIT/ZnO) complexes useful as antimicrobial agents because of their resistance to being leached from the substrate to which they are attached. The present invention is also directed to methods for preparing the BIT/ZnO complexes, to BIT/ZnO complexes prepared by the novel methods, to methods for using the BIT/ZnO complexes to inhibit microbial growth or reduce the level of bacteria on the surface of a substrate, and to substrates protected from microbial attack by being treated with the BIT/ZnO complexes. The present invention is further directed to compositions comprising 1,2-benzisothiazolin-3-one which has been immobilized with zinc oxide.
    • 本发明提供了可用作抗微生物剂的新型抗微生物固定化1,2-苯并异噻唑啉-3-酮/氧化锌(BIT / ZnO)络合物,因为它们能够抵抗从它们所连接的基质上浸出。 本发明还涉及制备BIT / ZnO复合物的方法,通过该新方法制备的BIT / ZnO复合物,使用BIT / ZnO复合物抑制微生物生长或降低表面细菌水平的方法 底物,以及通过用BIT / ZnO复合物处理而防止微生物侵袭的基材。 本发明进一步涉及含有固定有氧化锌的1,2-苯并异噻唑啉-3-酮的组合物。
    • 10. 发明申请
    • IMMOBILIZED 1,2-BENZISOTHIAZOLIN-3-ONE
    • 固定化1,2-苯并噻唑啉-3-酮
    • WO2007139645A2
    • 2007-12-06
    • PCT/US2007/010124
    • 2007-04-20
    • TROY TECHNOLOGY CORPORATION, INC.LINDNER, Wolfgang
    • LINDNER, Wolfgang
    • A61K31/555C07F3/06
    • C07F3/003A61K31/555C07B2200/11
    • The present invention provides novel antimicrobial immobilized 1,2- benzisothiazolin-3-one/zinc oxide (BIT/ZnO) complexes useful as antimicrobial agents because of their resistance to being leached from the substrate to which they are attached. The present invention is also directed to methods for preparing the BIT/ZnO complexes, to BIT/ZnO complexes prepared by the novel methods, to methods for using the BIT/ZnO complexes to inhibit microbial growth or reduce the level of bacteria on the surface of a substrate, and to substrates protected from microbial attack by being treated with the BIT/ZnO complexes. The present invention is further directed to compositions comprising 1,2-benzisothiazolin-3-one which has been immobilized with zinc oxide.
    • 本发明提供了抗微生物固定化的1,2-苯并异噻唑啉-3-酮/氧化锌(BIT / ZnO)复合物,因为它们耐受从它们所连接的底物浸出,因此可用作抗微生物剂。 本发明还涉及用于制备BIT / ZnO复合物的方法,通过新方法制备的BIT / ZnO复合物,使用BIT / ZnO复合物抑制微生物生长或降低表面上细菌水平的方法 底物,以及通过用BIT / ZnO复合物处理而防止微生物侵袭的底物。 本发明还涉及已经用氧化锌固定的1,2-苯并异噻唑啉-3-酮的组合物。