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1. 发明申请

WO2008079575A1 LONG NOSE MANIPULATABLE CATHETER 审中-公开
标题翻译：长期可编程导管
公开(公告)号：WO2008079575A1
公开(公告)日：2008-07-03
申请号：PCT/US2007/085620
申请日：2007-11-27
申请人： MICRUS ENDOVASCULAR CORPORATION , LEVINE, Marc-Alan , HEBERT, Stephen , BRETON, Thomas, G. , WATSON, David, A.
发明人： LEVINE, Marc-Alan , HEBERT, Stephen , BRETON, Thomas, G. , WATSON, David, A.
IPC分类号： A61M25/00 , A61M25/01 , A61M25/09
CPC分类号： A61M25/008 , A61M25/0068 , A61M25/0136 , A61M25/0147 , A61M25/10 , A61M2025/015 , A61M2025/1079 , A61M2025/1093
摘要： The long nose manipulatable catheter includes a main lumen (55), a wire lumen (60) with a push-pull wire (62) therethrough, and a flexible joint region. (58) The catheter section includes a control (240) including a handle (238) and a wire control (240) member engaging the push-pull wire for manipulating the flexible joint region. The push-pull wire (62) may be tapered, having a proximal portion of a first diameter and a smaller diameter distal portion. A coil may be placed around the smaller diameter to prevent buckling of the smaller diameter portion. A strapping coil may also disposed around the outside of the catheter,' and an outer covering may be disposed around the strapping. coil. An outer covering of a mesh may also be disposed around the distal tip of the catheter.
摘要翻译：长鼻可操纵导管包括主腔（55），具有穿过其的推挽线（62）的线腔（60）和柔性接合区域。（58）导管部分包括包括手柄（238）和接合推挽线的线控制（240）构件的控制器（240），用于操纵柔性接合区域。推拉线（62）可以是锥形的，具有第一直径的近端部分和较小直径的远端部分。线圈可以放置在较小直径周围以防止较小直径部分的弯曲。捆扎线圈也可以围绕导管的外侧设置，并且可以在捆扎带周围设置外覆盖层。线圈。网的外覆盖物也可以设置在导管的远侧末端周围。

2. 发明申请

WO2003073963A3 GUIDEWIRE LOADED STENT FOR DELIVERY THROUGH A CATHETER 审中-公开
公开(公告)号：WO2003073963A3
公开(公告)日：2003-09-12
申请号：PCT/US2003/004359
申请日：2003-02-14
申请人： COUNTER CLOCKWISE, INC. , HEBERT, Stephen , LEVINE, Marc-Alan
发明人： HEBERT, Stephen , LEVINE, Marc-Alan
IPC分类号： A61F2/06
摘要： The stent (28) delivery assembly can deliver and place a stent (28) within tortuous regions of the body which are accessible to guidewires (24, 34) but inaccessible to stenting catheters. The assembly comprises a guidewire (24, 34) covered in part by a retractable sheath (26) and a radially expandable stent (28) near or at the distal end of the guidewire (24). The whole assembly is advanced through conventional catheter (10) or it may be used alone. In either case, when the stent (28) is adjacent to a treatment site within the body, the sheath (26) is retracted proximally to expose the stent (28) for radial expansion into contact with the vessel wall. Radio-gpaque marker (30, 32) bands are optionally located on either side or both sides of the stent (28) on the guidewire (24, 34) body to aid in visual placement. The assembly can optionally include an expandable balloon (36) on the guidewire (24, 34) for different treatment modalities.

3. 发明申请

WO0215972A3 MANIPULATABLE DELIVERY CATHETER FOR OCCLUSIVE DEVICES 审中-公开
标题翻译：用于闭合装置的可操作的输送导管
公开(公告)号：WO0215972A3
公开(公告)日：2002-08-22
申请号：PCT/US0125780
申请日：2001-08-17
申请人： COUNTER CLOCKWISE INC , HEBERT STEPHEN , LEVINE MARC-ALAN
发明人： HEBERT STEPHEN , LEVINE MARC-ALAN
IPC分类号： A61M25/01 , A61M25/10 , A61F2/06
CPC分类号： A61M25/0147 , A61B17/12022 , A61B17/1204 , A61B17/12113 , A61B17/12136 , A61B17/1214 , A61B2017/1205 , A61M25/0053 , A61M25/0054 , A61M25/10 , A61M25/1006 , A61M2025/0034 , A61M2025/0037 , A61M2025/0039 , A61M2025/004 , A61M2025/0177 , A61M2025/018 , A61M2025/1052
摘要： A delivery catheter (23) with a flexible, proximally-manipulated hinge (32) or joint region and a balloon (30) may have a shaft (25) of varying flexibility which contains several lumen. The inner, or delivery, lumen generally may be used with a guidewire (12) to access target sites within the body via the flexible, small diameter vessels, and may be also used for placement of occlusive materials, e.g., in an aneurysm. The push/pull wire lumen contains a wire (21), which when manipulated, flexes the catheter's distal tip. Moreover, the delivery catheter can be twisted in a helical or corkscrew-like manner for traversing certain vasculature, by winding the push/pull wire within the catheter and fixedly attaching it. The catheter may further include an entry in the catheter wall to allow for the insertion of a guidewire; to facilitate the rapid exchange of catheter devices.
摘要翻译：具有柔性的，近端操纵的铰链（32）或关节区域和球囊（30）的输送导管（23）可具有包含数个内腔的具有不同柔性的杆（25）。内部或递送内腔通常可以与导丝（12）一起使用以经由柔性的小直径血管进入体内的目标部位，并且还可以用于例如在动脉瘤中放置闭塞性材料。推/拉线腔包含导线（21），当操纵导线时，其弯曲导管的远端。此外，通过将推拉导线卷绕在导管内并固定地连接导管，可以以螺旋状或类似螺丝起子的方式扭转输送导管以横穿某些脉管系统。导管还可以包括导管壁中的入口以允许导丝的插入; 以促进导管装置的快速交换。

4. 发明申请

WO2009126244A2 DEVICES, SYSTEMS, AND METHODS FOR JOINING BODY CONDUITS 审中-公开
标题翻译：装置，系统和接合体系的方法
公开(公告)号：WO2009126244A2
公开(公告)日：2009-10-15
申请号：PCT/US2009002151
申请日：2009-04-06
申请人： BIOABSORBABLE THERAPEUTICS , HNOJEWYJ OLEXANDER , RIVELLI PATRICK JR , LEVINE MARC-ALAN , HERBERT STEPHEN , SHAFFER TONY B , PIPLANI ALEC , CHEUNG DAVID
发明人： HNOJEWYJ OLEXANDER , RIVELLI PATRICK JR , LEVINE MARC-ALAN , HERBERT STEPHEN , SHAFFER TONY B , PIPLANI ALEC , CHEUNG DAVID
IPC分类号： A61M25/04
CPC分类号： A61F2/915 , A61B17/11 , A61B2017/1107 , A61F2/0095 , A61F2/064 , A61F2/88 , A61F2/91 , A61F2002/828 , A61F2002/91558 , A61F2210/0004 , A61F2220/0008 , A61F2230/0054 , A61F2250/0071
摘要： Devices, systems, and methods are sized and configured for joining body conduits, desirably without the use of tissue-penetrating fasteners.
摘要翻译：设备，系统和方法的尺寸和构造用于连接身体管道，理想地不使用组织穿透紧固件。

5. 发明申请

WO2003073963A2 GUIDEWIRE LOADED STENT FOR DELIVERY THROUGH A CATHETER 审中-公开
标题翻译：通过导管输送的GUIDEWIRE负载支架
公开(公告)号：WO2003073963A2
公开(公告)日：2003-09-12
申请号：PCT/US2003/004359
申请日：2003-02-14
申请人： COUNTER CLOCKWISE, INC. , HEBERT, Stephen , LEVINE, Marc-Alan
发明人： HEBERT, Stephen , LEVINE, Marc-Alan
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/95 , A61F2/958 , A61F2002/9583 , A61M25/09 , A61M2025/09008 , A61M2025/09183
摘要： A guidewire loaded stent for delivery through a catheter is described herein. The stent delivery assembly can deliver and place a stent within tortuous regions of the body which are accessible to guidewires but inaccessible to stenting catheters. The assembly comprises a guidewire covered in part by a ratractable sheath and a radially expandable stent near or at the distal end of the guidewire. The whole assembly is advanced through conventional catheters or it may be used alone. In either case, when the stent is adjacent to a treatment site within the body, the sheath is retracted proximally to expose the stent for radial expansion into contact with the vessel wall. Radio-opaque marker bands are optionally located on either side or both sides of the stent on the guidewire body to aid in visual placement. The assembly can optionally include an expandable balloon on the guidewire for different treatment modalities.
摘要翻译：本文描述了用于通过导管递送的导丝加载的支架。支架输送组件可以将支架输送并放置在身体的曲折区域内，所述曲折区域可以被引导线接近，但是对于支架置入导管是不可接近的。该组件包括一部分由可伸缩鞘覆盖的导丝和在该导丝的远端附近或其远端处的可径向扩张的支架。整个组件通过常规导管进行，或者可以单独使用。在任一情况下，当支架邻近体内的治疗部位时，护套向近侧缩回以暴露支架用于径向膨胀以与血管壁接触。无线电不透明的标记带可选地位于导线主体上的支架的两侧或两侧，以帮助视觉放置。组件可以可选地包括在导丝上的可膨胀气囊用于不同的治疗方式。

6. 发明申请

WO0004838A9 FLEXIBLE FLOW APPARATUS AND METHOD FOR THE DISRUPTION OF OCCLUSIONS 审中-公开
标题翻译：柔性流动装置及其破坏方法
公开(公告)号：WO0004838A9
公开(公告)日：2000-05-25
申请号：PCT/US9916371
申请日：1999-07-20
申请人： ENDOVASIX INC , LEVINE MARC ALAN , SUCGANG EDUARDO U , HEBERT STEPHEN J , GATCHALIAN ESTELA D , TRAN QUANG Q , ESCH VICTOR C
发明人： LEVINE MARC-ALAN , SUCGANG EDUARDO U , HEBERT STEPHEN J , GATCHALIAN ESTELA D , TRAN QUANG Q , ESCH VICTOR C
IPC分类号： A61B18/20 , A61B17/00 , A61B18/22 , A61B18/24 , A61B18/26 , A61N5/06
CPC分类号： A61B18/26 , A61B18/245 , A61B2017/00176 , A61B2018/2211
摘要： The invention encompasses methods and flexible apparatus for creating fluid flow from one location to another through the repetitive expansion and collapse of bubbles generated as a result of the absorption of repetitive pulses of radiation in a fluid. This pumping phenomenon can be used to aid removal of a total or partial occlusion in a body passage by disrupting the surface of the occlusion with acoustic shock and pressure waves and/or by causing mechanical disruption of the occlusive material. Flexibility is improved with choice of materials and particular constructions.
摘要翻译：本发明包括用于通过由于在流体中吸收重复的辐射脉冲而产生的气泡的重复膨胀和塌缩来产生从一个位置到另一个位置的流体流动的方法和柔性装置。这种泵送现象可以用于通过用声波冲击和压力波破坏闭塞表面和/或通过引起封闭材料的机械破坏来去除身体通道中的全部或部分闭塞。通过选择材料和特定结构可以提高灵活性。

7. 发明申请

WO2009149457A1 PROSTHESIS AND DELIVERY SYSTEM 审中-公开
标题翻译： PROSTHESIS和交付系统
公开(公告)号：WO2009149457A1
公开(公告)日：2009-12-10
申请号：PCT/US2009/046633
申请日：2009-06-08
申请人： BAY STREET MEDICAL, INC. , HEBERT, Stephen , LEVINE, Marc-alan
发明人： HEBERT, Stephen , LEVINE, Marc-alan
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61B50/30 , A61F2/0095 , A61F2/91 , A61F2/915 , A61F2002/91558 , A61F2002/91583 , A61F2002/9505 , A61F2002/9665 , A61F2220/005 , A61F2220/0058 , A61F2230/0054 , A61F2250/0098
摘要： A prosthesis delivery system including a prosthesis mounted on an elongate member. The prosthesis has longitudinally offset first and second locking members positioned on the prosthesis. The first and second locking members are configured to engage opposing proximal and distal sides of a radially extending member on the elongate member to lock or limit the longitudinal position of the prosthesis on the elongate member during delivery of the prosthesis to a treatment site.
摘要翻译：一种假体递送系统，包括安装在细长构件上的假体。假体已纵向地偏置位于假体上的第一和第二锁定构件。第一和第二锁定构件构造成接合在细长构件上的径向延伸构件的相对近侧和远侧，以在将假体递送到治疗部位期间锁定或限制假体在细长构件上的纵向位置。

8. 发明申请

WO2009012417A1 RADIALLY EXPANDABLE STENT 审中-公开
标题翻译：放射性可扩展的
公开(公告)号：WO2009012417A1
公开(公告)日：2009-01-22
申请号：PCT/US2008/070382
申请日：2008-07-17
申请人： BAY STREET MEDICAL, INC. , HEBERT, Stephen , LEVINE, Marc-alan , LEYNOV, Aleksandr
发明人： HEBERT, Stephen , LEVINE, Marc-alan , LEYNOV, Aleksandr
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2002/91583 , A61F2230/0054
摘要： A highly compressible stent is described. The stent includes a plurality of circumferentially offset and interconnected undulating rings having intermediate struts disposed between at least some of the undulating ring struts.
摘要翻译：描述了高度可压缩的支架。支架包括多个周向偏移和相互连接的起伏环，其中间支柱设置在至少一些起伏的环形支柱之间。

9. 发明申请

WO2004004801A8 BALLOON CATHETER HAVING AN EXPANDABLE DISTAL END 审中-公开
标题翻译：具有可扩展距离的气球导管
公开(公告)号：WO2004004801A8
公开(公告)日：2004-04-29
申请号：PCT/US0321103
申请日：2003-07-03
申请人： COUNTER CLOCKWISE INC , HEBERT STEPHEN , LEVINE MARC-ALAN
发明人： HEBERT STEPHEN , LEVINE MARC-ALAN
IPC分类号： A61F2/958 , A61M25/00 , A61M
CPC分类号： A61M25/0021 , A61M25/0023 , A61M25/0045 , A61M25/0053 , A61M25/0075 , A61M25/1006 , A61M2025/0004 , A61M2025/1052
摘要： A catheter assembly having a balloon integrated at its distal tip. The balloon, while inflated, prevents the back-flow of fluid introduced through the catheter assembly into vessels or ducts in a mammalian subject. The catheter has an inner lumen and a coaxial outer lumen. An inflatable member attached at the distal end of the catheter forms the balloon. The outer lumen provides the channel for inflating the balloon and the inner lumen provides the channel for a guide wire or for use in delivery of fluids or particles. This low profile balloon catheter design allows for high maneuverability and also facilitates the manufacture of small diameter balloon catheters.
摘要翻译：导管组件，其具有在其远端顶端集成的气囊。气囊在充气时防止通过导管组件引入的流体在哺乳动物受试者中回流到血管或导管中。导管具有内腔和同轴的外腔。附接在导管远端的可膨胀构件形成气囊。外腔提供用于使气囊膨胀的通道，并且内腔提供导丝的通道或用于输送流体或颗粒。这种低轮廓气囊导管设计允许高机动性，并且还有助于制造小直径气囊导管。

10. 发明申请

WO2004004801A2 BALLOON CATHETER HAVING AN EXPANDABLE DISTAL END 审中-公开
标题翻译：气球导管具有可扩展的末端
公开(公告)号：WO2004004801A2
公开(公告)日：2004-01-15
申请号：PCT/US0321103
申请日：2003-07-03
申请人： COUNTER CLOCKWISE INC , HEBERT STEPHEN , LEVINE MARC-ALAN
发明人： HEBERT STEPHEN , LEVINE MARC-ALAN
IPC分类号： A61F2/958 , A61M25/00 , A61M
CPC分类号： A61M25/0021 , A61M25/0023 , A61M25/0045 , A61M25/0053 , A61M25/0075 , A61M25/1006 , A61M2025/0004 , A61M2025/1052
摘要： A catheter assembly having a balloon integrated at its distal tip. The balloon, while inflated, prevents the back-flow of fluid introduced through the catheter assembly into vessels or ducts in a mammalian subject. The catheter has an inner lumen and a coaxial outer lumen. An inflatable member attached at the distal end of the catheter forms the balloon. The outer lumen provides the channel for inflating the balloon and the inner lumen provides the channel for a guide wire or for use in delivery of fluids or particles. This low profile balloon catheter design allows for high maneuverability and also facilitates the manufacture of small diameter balloon catheters.
摘要翻译：导管组件在其远端尖端集成了一个气囊。球囊在膨胀时阻止通过导管组件引入的流体回流到哺乳动物受试者的血管或导管中。导管具有内腔和同轴外腔。连接在导管远端的可充气构件形成气囊。外腔为气囊充气提供通道，内腔为导丝提供通道或用于输送流体或颗粒。这种小型气囊导管设计允许高度可操作性并且还便于制造小直径气囊导管。

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