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    • 2. 发明申请
    • SYSTEMS AND METHODS FOR COMPOSITE ELASTOGRAPHY AND WAVE IMAGING
    • 用于复合光学和波形成像的系统和方法
    • WO2008027520A2
    • 2008-03-06
    • PCT/US2007/019149
    • 2007-08-30
    • THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKKONOFAGU, Elisa, E.FUNG-KEE-FUNG, SimonWANG, ShougangLEE, Wei-Ning
    • KONOFAGU, Elisa, E.FUNG-KEE-FUNG, SimonWANG, ShougangLEE, Wei-Ning
    • G06F19/00
    • G01S7/52057A61B8/08A61B8/0883A61B8/0891A61B8/463A61B8/485A61B8/5284A61B8/543G01S7/52042G01S7/52074G01S7/52088
    • Systems and methods for composite elastography and wave imaging are presented. In exemplary embodiments of the present invention an imaging modality field of view, such as, for example, that of ultrasound, can be divided into N sectors, each having 1/Nth of a full field of view. In exemplary embodiments of the present invention a temporal series of 2D or 3D ultrasound images for each of the N sectors can be acquired over a duration of one or more periods of a periodic signal. Substantially simultaneously, such a periodic signal can also be acquired, wherein each of said series of 2D ultrasound images for each sector can be triggered or gated using said periodic signal. For example, for ultrasound imaging of the heart, an ECG signal can function as such a periodic signal. The data from the various N sectors can be synchronized in time using the ECG signals, and the ultrasound signals from each of the N sectors combined to generate a series of composite ultrasound images at the frame rate of the individual sectors. In exemplary embodiments of the present invention such a composite image can be further processed to estimate displacement between consecutive frames, remove noise, accumulate displacement with time for an entire cardiac cycle, and derive strain in the cardiac muscle, vessel or any other organ or tissue under motion. In exemplary embodiments of the present invention the derived strain data can be overlaid onto all or part of the composite ultrasound images, and one or more of such overlaid images can be displayed to a user.
    • 提出了复合弹性成像和波浪成像的系统和方法。 在本发明的示例性实施例中,诸如例如超声波的成像模态视野可以被划分为N个扇区,每个扇区具有全视野的1/N。 在本发明的示例性实施例中,可以在周期性信号的一个或多个周期的持续时间内获取用于N个扇区中的每一个的时间序列的2D或3D超声图像。 基本上同时,也可以获取这样的周期性信号,其中可以使用所述周期信号来触发或门控用于每个扇区的所述一系列2D超声图像。 例如,对于心脏的超声成像,ECG信号可以起到这样的周期性信号的作用。 来自各N个扇区的数据可以使用ECG信号在时间上同步,并且来自组合的N个扇区中的每个的超声信号以各个扇区的帧速率生成一系列复合超声图像。 在本发明的示例性实施例中,可以进一步处理这样的合成图像以估计连续帧之间的位移,去除噪声,随着时间的推移而累积整个心动周期,并且导致心肌,血管或任何其他器官或组织中的应变 动议。 在本发明的示例性实施例中,导出的应变数据可以覆盖在全部或部分复合超声图像上,并且可以向用户显示这些重叠图像中的一个或多个。