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    • 1. 发明申请
    • REAGENTS FOR ELECTROCHEMICAL TEST STRIPS
    • 电化学测试试剂
    • WO2013016379A1
    • 2013-01-31
    • PCT/US2012048049
    • 2012-07-25
    • AGAMATRIX INCHARDING IANLEE MARY YTAN SANDIE
    • HARDING IANLEE MARY YTAN SANDIE
    • C12Q1/26C12Q1/54
    • C12Q1/26G01N33/521
    • A dry reagent composition that includes an active redox enzyme that oxidizes an analyte as a specific substrate to produce an inactive reduced form of the enzyme; and a salt of ferricyanide provides improved performance in electrochemical test strips such as those used for detection of glucose. The salt of ferricyanide consists of ferricyanide and positively- charged counter ions, and the positively charged counter ions are selected such that the salt of ferricyanide is soluble in water, and such that the salt of ferricyanide or the crystalline phase of the salt of ferricyanide has a solubility in water and/or a lower E0 eff at a concentration of 100 mM than potassium ferricyanide. For example, the salt of ferricyanide may be tetramethylammonium ferricyanide.
    • 一种干试剂组合物,其包含将分析物氧化为特定底物以产生酶的无活性还原形式的活性氧化还原酶; 并且铁氰化物的盐在诸如用于检测葡萄糖的电化学测试条中提供了改进的性能。 铁氰化物的盐由铁氰化物和带正电的抗衡离子组成,并且选择带正电的对离子使得铁氰化物的盐可溶于水,并且使铁氰化物的盐或铁氰化物盐的结晶相具有 在水中的溶解度和/或比铁氰化钾在100mM浓度下更低的E0 eff。 例如,铁氰化物的盐可以是四甲基铵铁氰化物。