会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 1. 发明申请
    • MEMORY COMMAND DELAY BALANCING IN A DAISY-CHAINED MEMORY TOPOLOGY
    • 内存命令延迟平衡在一个连贯的内存拓扑中
    • WO2006023360A1
    • 2006-03-02
    • PCT/US2005/028535
    • 2005-08-09
    • MICRON TECHNOLOGY, INC.LARSON, Douglas, Alan
    • LARSON, Douglas, Alan
    • G06F13/16
    • G11C7/22G06F3/0611G06F3/0629G06F3/0671G06F13/4243Y02D10/14Y02D10/151
    • A methodology for a daisy-chained memory topology wherein, in addition to the prediction of the timing of receipt of a response from a memory module (DIMM), the memory controller can effectively predict when a command sent by it will be executed by the addressee DIMM. By programming DIMM-specific command delay in the DIMM's command delay unit, the command delay balancing methodology according to the present disclosure "normalizes" or "synchronizes" the execution of the command signal across all DIMMs in the memory channel. With such ability to predict command execution timing, the memory controller can efficiently control power profile of all the DRAM devices (or memory modules) on a daisy-chained memory channel. A separate DIMM-specific response delay unit in the DIMM may also be programmed to provide DIMM-specific delay compensation in the response path, further allowing the memory controller to accurately ascertain the timing of receipt of a response thereat, and, hence, to better manage further processing of the response.
    • 一种菊花链存储器拓扑的方法,其中除了预测从存储器模块(DIMM)的响应的接收时间之外,存储器控制器可以有效地预测由其发送的命令何时由收件人执行 DIMM。 通过在DIMM的命令延迟单元中编程DIMM特定的命令延迟,根据本公开的命令延迟平衡方法“在规范化”或“同步”命令信号在存储器通道中的所有DIMM上的执行。 通过这种预测命令执行定时的能力,存储器控制器可以有效地控制菊花链式存储器通道上的所有DRAM设备(或存储器模块)的功率分布。 还可以将DIMM中的单独的DIMM特定的响应延迟单元编程为在响应路径中提供特定于DIMM的延迟补偿,进一步允许存储器控制器准确地确定在那里接收响应的时间,并因此更好地 管理响应的进一步处理。
    • 3. 发明申请
    • RECOMBINANT INTERFERON-BETA WITH ENHANCED BIOLOGICAL ACTIVITY
    • 重组干扰素β具有增强的生物活性
    • WO2008020968A3
    • 2008-05-29
    • PCT/US2007016722
    • 2007-07-24
    • NOVARTIS VACCINES & DIAGNOSTICJOHNSON-JACKSON DEBORAHFURUYA KENJIZAROR ISABELLARSON DOUGLAS
    • JOHNSON-JACKSON DEBORAHFURUYA KENJIZAROR ISABELLARSON DOUGLAS
    • C07K14/565
    • C07K14/565
    • Human interferon-ß protein analogs in which the asparagine at position 25, numbered in accordance with native human interferon-ß, is recombinantly replaced with an aspartate residue exhibit a biological activity of human interferon-ß (e.g. IFN-ß 1b) at an increased level relative to IFN-ß 1b. These analogs are obtained by introducing a gene coding for Asp25 IFN-ß into a cell and expressing the recombinant protein. The resulting IFN-ß protein analog is suitable for large scale manufacturing for incorporation in HA-containing or HA-free therapeutics for treatment of diseases including multiple sclerosis. A reduced Lys endoproteinase-C peptide map technique that produces a fingerprint profile for proteins using an enzymatic digest followed by RP-HPLC is also useful in quality control as an ID test for the IFN-ß protein analog products.
    • 人类干扰素-β蛋白类似物,其中根据天然人干扰素-β编号的25位天冬酰胺被天冬氨酸残基重组取代,表现出人类干扰素-β(例如IFN-β1b)的生物学活性增加 水平相对于IFN-β1b。 这些类似物通过将编码Asp25IFN-β的基因导入细胞并表达重组蛋白来获得。 所得到的IFN-β蛋白类似物适合于大规模生产以掺入含有HA或HA的治疗剂中,用于治疗包括多发性硬化症的疾病。 利用酶促消化产生指纹图谱,然后进行RP-HPLC的还原Lys内切蛋白酶-C肽图谱技术在质量控制中也可用作IFN-β蛋白类似物产品的ID测试。
    • 6. 发明申请
    • RECOMBINANT INTERFERON-BETA WITH ENHANCED BIOLOGICAL ACTIVITY
    • 重组干扰素与增强的生物活性
    • WO2008020968A8
    • 2009-08-06
    • PCT/US2007016722
    • 2007-07-24
    • NOVARTIS AGJOHNSON-JACKSON DEBORAHFURUYA KENJIZAROR ISABELLARSON DOUGLAS
    • JOHNSON-JACKSON DEBORAHFURUYA KENJIZAROR ISABELLARSON DOUGLAS
    • C07K14/565
    • C07K14/565
    • Human interferon-ß protein analogs in which the asparagine at position 25, numbered in accordance with native human interferon-ß, is recombinantly replaced with an aspartate residue exhibit a biological activity of human interferon-ß (e.g. IFN-ß 1b) at an increased level relative to IFN-ß 1b. These analogs are obtained by introducing a gene coding for Asp25 IFN-ß into a cell and expressing the recombinant protein. The resulting IFN-ß protein analog is suitable for large scale manufacturing for incorporation in HA-containing or HA-free therapeutics for treatment of diseases including multiple sclerosis. A reduced Lys endoproteinase-C peptide map technique that produces a fingerprint profile for proteins using an enzymatic digest followed by RP-HPLC is also useful in quality control as an ID test for the IFN-ß protein analog products.
    • 人类干扰素-β蛋白类似物,其中根据天然人类干扰素β编号的位置25的天冬酰胺用天冬氨酸残基重组替代,表现出人干扰素β(例如IFN-β1b)在增加的生物活性 水平相对于IFN-β1b。 这些类似物通过将编码Asp25 IFN-β的基因导入细胞并表达重组蛋白而获得。 所得到的IFN-β蛋白类似物适用于大规模制造,用于掺入含HA或不含HA的治疗剂中用于治疗包括多发性硬化的疾病。 使用酶促消化产生RP-HPLC产生蛋白质指纹图谱的降低的Lys内蛋白酶-C肽图技术在用于IFN-β蛋白模拟产物的ID测试的质量控制中也是有用的。
    • 9. 发明申请
    • CALIBRATION METHOD FOR SYSTEM PERFORMANCE VALIDATION OF AUTOMATIC TEST EQUIPMENT
    • 自动测试设备的系统性能验证校准方法
    • WO2004083880A1
    • 2004-09-30
    • PCT/JP2004/003832
    • 2004-03-22
    • ADVANTEST CORPORATIONLARSON, DouglasLE, AnthonyTONG, Carol, QiaoRAJSUMAN, Rochit
    • LARSON, DouglasLE, AnthonyTONG, Carol, QiaoRAJSUMAN, Rochit
    • G01R31/319
    • G01R31/3191G01R31/31922
    • An ATE calibration method and system that does not require external test equipment to calibrate individual functional pins and provides balanced timing skews among the functional pins and pincards is disclosed. A functional pin in the test system is selected as a reference or "golden" pin and another is selected as a precision measurement unit (PMU). External test equipment and the reference PMU are used to measure the AC and DC characteristics of the reference pin, and any deviation represents a measurement error in the reference PMU. All functional pins in the test system can be measured against the reference pin using the reference PMU, taking into account the measurement error, without the need for external test equipment. To ensure that skews are balanced among all pins, the location of the reference pin is selected to be as close as possible to the midpoint of the functional pin range.
    • 公开了一种不需要外部测试设备来校准各个功能引脚并在功能引脚和引脚卡之间提供平衡的时序偏移的ATE校准方法和系统。 选择测试系统中的功能引脚作为参考或“黄金”引脚,另一个选择为精密测量单元(PMU)。 外部测试设备和参考PMU用于测量参考引脚的交流和直流特性,任何偏差表示参考PMU中的测量误差。 测试系统中的所有功能引脚可以使用参考PMU测量参考引脚,同时考虑到测量误差,无需外部测试设备。 为了确保所有引脚之间的偏差平衡,参考引脚的位置选择为尽可能靠近功能引脚范围的中点。