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1. 发明申请

WO2012105813A3 USE OF ICAM-1 FOR PREVENTION OR TREATMENT OF NEUROLOGICAL DISEASES 审中-公开
公开(公告)号：WO2012105813A3
公开(公告)日：2012-08-09
申请号：PCT/KR2012/000788
申请日：2012-02-01
申请人： MEDIPOST CO., LTD. , YANG, Yoon-Sun , OH, Won Il , CHANG, Jong Wook , KIM, Ji Hyun
发明人： YANG, Yoon-Sun , OH, Won Il , CHANG, Jong Wook , KIM, Ji Hyun
IPC分类号： A61K38/16 , A61K38/17 , A61K48/00 , A61P25/00
摘要： The present invention relates to a pharmaceutical composition for the prevention or treatment of neurological disorders, comprising an ICAM-1 (intercellular adhesion molecule-1) protein, or a fragment or a variant thereof as an active ingredient, which can increase the expression of neprilysin to remove amyloid-beta (A¥, a cause of dementia, and is thus useful in preventing or treating a neurological disease including Alzheimer¡s disease.

2. 发明申请

WO2011052950A2 PHARMACEUTICAL COMPOSITION COMPRISING INDOLE COMPOUND 审中-公开
标题翻译：包含吲哚化合物的药物组合物
公开(公告)号：WO2011052950A2
公开(公告)日：2011-05-05
申请号：PCT/KR2010/007344
申请日：2010-10-25
申请人： LG LIFE SCIENCES LTD. , KIM, Soon Ha , KIM, Hyoung Jin , PARK, Heui Sul , GU, Seon Yeong , KWAK, Hyo Shin , PARK, Du Hee , KIM, Hyo Soo , CHO, Hyun Jai , KIM, Ji Hyun , KIM, Ju Young , PARK, Kwang Min
发明人： KIM, Soon Ha , KIM, Hyoung Jin , PARK, Heui Sul , GU, Seon Yeong , KWAK, Hyo Shin , PARK, Du Hee , KIM, Hyo Soo , CHO, Hyun Jai , KIM, Ji Hyun , KIM, Ju Young , PARK, Kwang Min
IPC分类号： A61K31/404 , A61P29/00 , A61P19/02 , A61P7/08 , A61P19/10
CPC分类号： A61K31/541 , A61K8/492 , A61K31/404 , A61K31/4184 , A61K31/427 , A61K31/496 , A61K31/497 , A61K2800/522 , A61Q19/00 , C07D413/04 , C07D417/04 , C07D417/14 , C07D471/04 , C07D487/04
摘要： The present invention relates to a pharmaceutical composition comprising a compound of formula (1), (2) or (3) as defined in the specification for the prevention or treatment of diseases associated with oxidative stress, mitochondria dysfunction, hypoxic injury, necrosis and/or ischemic reperfusion injury, and a cosmetic composition comprising an indole compound having an antioxidant effect.
摘要翻译：本发明涉及药物组合物，其包含如说明书中定义的式（1），（2）或（3）化合物，其用于预防或治疗与氧化应激，线粒体功能障碍，缺氧损伤，坏死和/ 或缺血再灌注损伤，以及包含具有抗氧化作用的吲哚化合物的化妆品组合物。

3. 发明申请

WO2011027990A2 EXTRACELLULAR VESICLES DERIVED FROM GRAM-POSITIVE BACTERIA, AND USE THEREOF 审中-公开
标题翻译：来源于革兰阳性细菌的细胞外液及其用途
公开(公告)号：WO2011027990A2
公开(公告)日：2011-03-10
申请号：PCT/KR2010005721
申请日：2010-08-26
申请人： AEON MEDIX INC , GHO YONG SONG , KIM YOON KEUN , LEE EUN YOUNG , HONG SUNG WOOK , KIM JI HYUN , CHOI SENG JIN
发明人： GHO YONG SONG , KIM YOON KEUN , LEE EUN YOUNG , HONG SUNG WOOK , KIM JI HYUN , CHOI SENG JIN
IPC分类号： C12N1/00 , A61K9/133 , A61K35/74 , A61K39/00 , C12Q1/68 , C12R1/44 , G01N33/53
CPC分类号： C12Q1/6883 , A01K2207/00 , A01K2267/0375 , C12P1/04 , C12Q2600/158 , Y02P20/582
摘要： The present invention relates to extracellular vesicles (EVs) derived from gram-positive bacteria. In detail, the present invention provides animal models of disease using extracellular vesicles derived from gram-positive bacteria, provides a method for screening an active candidate substance which is capable of preventing or treating diseases through the animal models of disease, provides vaccines for preventing or treating diseases caused by extracellular vesicles derived from gram-positive bacteria, and provides a method for diagnosing the causative factors of diseases caused by gram-positive bacteria using extracellular vesicles.
摘要翻译：本发明涉及源自革兰氏阳性细菌的细胞外囊泡（EV）。具体而言，本发明提供了使用来自革兰氏阳性细菌的细胞外囊泡的疾病动物模型，提供了筛选能够通过动物疾病模型预防或治疗疾病的活性候选物质的方法，提供了用于预防或治疗治疗由革兰氏阳性细菌产生的细胞外囊泡引起的疾病，并提供一种使用细胞外囊泡来诊断由革兰氏阳性细菌引起的疾病的致病因子的方法。

4. 发明申请

WO2009154330A1 AN SYNTHETIC PEPTIDE CONTAINING BONE FORMING PEPTIDE 2(BFP 2) FOR STIMULATING OSTEOBLAST DIFFERENTIATION, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SYNTHETIC PEPTIDE 审中-公开
标题翻译：含有骨形成肽2（BFP 2）的合成肽用于刺激OSTEOBLAST分化，以及包含合成肽的药物组合物
公开(公告)号：WO2009154330A1
公开(公告)日：2009-12-23
申请号：PCT/KR2008/006059
申请日：2008-10-15
申请人： INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY , YOON, Taek Rim , KIM, Hyung Keun , KIM, Ji Hyun
发明人： YOON, Taek Rim , KIM, Hyung Keun , KIM, Ji Hyun
IPC分类号： C07K7/00
CPC分类号： C07K14/51
摘要： Disclosed herein is an osteogenic synthetic peptide, derived from bone morphogenetic protein-7, consisting of a sequence of 15 amino acid residues (BFP2). Provided are also a pharmaceutical composition and a medium composition comprising the same. Having remarkable activity related to promoting osteoblast differentiation, the osteogenic synthetic peptide is very useful in the treatment of osteoporosis, bone defects and/or osteoarthritis.
摘要翻译：本文公开了衍生自骨形态发生蛋白-7的成骨合成肽，其由15个氨基酸残基（BFP2）的序列组成。还提供了药物组合物和包含其的培养基组合物。与促进成骨细胞分化相关的显着活性，成骨合成肽在治疗骨质疏松症，骨缺损和/或骨关节炎方面非常有用。

5. 发明申请

WO2013002621A3 SECONDARY BATTERY HAVING IMPROVED CONTACT RESISTANCE 审中-公开
标题翻译：二次电池具有改善的接触电阻
公开(公告)号：WO2013002621A3
公开(公告)日：2013-02-28
申请号：PCT/KR2012005249
申请日：2012-07-02
申请人： LG CHEMICAL LTD , KIM SEONG-YONG , KIM JI-HYUN , LEE HAN-HO
发明人： KIM SEONG-YONG , KIM JI-HYUN , LEE HAN-HO
IPC分类号： H01M2/26
CPC分类号： H01M2/02 , H01M2/0212 , H01M2/266 , H01M2/30 , H01M10/0436 , H01M10/052 , H01M10/058
摘要： The present invention relates to a secondary battery in which a structure of an electrode tab and a lead is improved so as to reduce contact resistance. According to the present invention, the secondary battery with improved contact resistance comprises: an electrode assembly formed by alternately stacking a positive electrode plate having a positive electrode tab, a negative electrode plate having a negative electrode tab, and a separation film; a battery case for accommodating the electrode assembly; and a negative electrode lead electrically connected to the negative electrode tab, wherein the battery case is sealed while accommodating the electrode assembly, and the negative electrode lead and the positive electrode tab are exposed outwardly from the battery case.
摘要翻译：本发明涉及一种二次电池，其中改进了电极接线片和引线的结构以降低接触电阻。根据本发明，具有改进的接触电阻的二次电池包括：电极组件，通过交替地堆叠具有正电极接片的正电极板，具有负电极接片的负电极板和隔离膜而形成; 用于容纳电极组件的电池壳体; 以及与负极片电连接的负极引线，其中，电池壳体在容纳电极组件的同时被密封，并且负极引线和正极片从电池壳体向外暴露。

6. 发明申请

WO2012118284A3 METHOD FOR CALCULATING A THERMAL PROTECTION FACTOR 审中-公开
标题翻译：计算热保护系数的方法
公开(公告)号：WO2012118284A3
公开(公告)日：2012-11-22
申请号：PCT/KR2012001145
申请日：2012-02-15
申请人： AMOREPACIFIC CORP , SNU R&DB FOUNDATION , SON EUI DONG , KIM HYEON CHUNG , KIM JI HYUN , CHOI HYUN JUNG , NAM GAE WON , LEE TAE RYONG , CHUNG JIN HO , JIN SEON PIL
发明人： SON EUI DONG , KIM HYEON CHUNG , KIM JI HYUN , CHOI HYUN JUNG , NAM GAE WON , LEE TAE RYONG , CHUNG JIN HO , JIN SEON PIL
IPC分类号： A61B5/00
CPC分类号： G01K11/00 , A61B5/01 , A61B5/441
摘要： The present invention relates to a method for calculating a thermal protection factor, wherein the method comprises the steps of: applying heat to a first area coated with a thermal protection material, and a second area not coated with the thermal protection material; measuring the respective saturation temperatures of the first area and second area; calculating a first energy by dividing the energy corresponding to the heat applied to the first area by the saturation temperature of the first area; calculating a second energy by dividing the energy corresponding to the heat applied to the second area by the saturation temperature of the second area; and calculating the thermal protection factor of a thermal protection material by dividing the first energy by the second energy or dividing the difference between the first energy and the second energy by the first energy.
摘要翻译：本发明涉及一种用于计算热防护系数的方法，其中该方法包括以下步骤：向涂覆有热防护材料的第一区域和未涂覆有防热材料的第二区域施加热量; 测量第一区域和第二区域各自的饱和温度; 通过将与施加到第一区域的热量对应的能量除以第一区域的饱和温度来计算第一能量; 通过将与施加到第二区域的热量对应的能量除以第二区域的饱和温度来计算第二能量; 以及通过将所述第一能量除以所述第二能量或者将所述第一能量与所述第二能量之差除以所述第一能量来计算热防护材料的热防护系数。

7. 发明申请

WO2012074246A3 METHOD FOR SCREENING SKIN AGING-RELATED GENES AND MATERIALS FOR PREVENTING SKIN AGING 审中-公开
标题翻译：用于筛选皮肤老化相关基因和预防皮肤老化的材料的方法
公开(公告)号：WO2012074246A3
公开(公告)日：2012-10-04
申请号：PCT/KR2011009057
申请日：2011-11-25
申请人： AMOREPACIFIC CORP , SNU R&DB FOUNDATION , SON EUI DONG , LEE JIN YOUNG , NA YONG JU , KIM HYAE KYOUNG , KIM JI HYUN , AHN SOO MI , KIM HAN KON , CHUNG JIN HO , PARK CHI HYUN , SEO EUN YOUNG , LEE MIN JUNG , OH INN GYUNG , YOON HYUN SUN
发明人： SON EUI DONG , LEE JIN YOUNG , NA YONG JU , KIM HYAE KYOUNG , KIM JI HYUN , AHN SOO MI , KIM HAN KON , CHUNG JIN HO , PARK CHI HYUN , SEO EUN YOUNG , LEE MIN JUNG , OH INN GYUNG , YOON HYUN SUN
IPC分类号： C12Q1/68 , C12N15/12
CPC分类号： C12Q1/6809 , C12Q1/6883 , C12Q2600/158
摘要： The present invention relates to a method for screening skin aging-specific genes and a method for screening anti-aging materials by controlling the expression of the genes. The invention can provide a new material having an effect on the prevention of skin aging and the treatment of skin diseases by obtaining new target genes related to skin aging and controlling the expression of the genes.
摘要翻译：本发明涉及一种筛选皮肤老化特异性基因的方法以及通过控制基因表达来筛选抗衰老材料的方法。本发明可以通过获得与皮肤老化相关的新靶基因并控制基因的表达，提供一种具有预防皮肤老化和皮肤病治疗效果的新材料。

8. 发明申请

WO2011145816A3 ROLL MASK PACK 审中-公开
公开(公告)号：WO2011145816A3
公开(公告)日：2012-04-19
申请号：PCT/KR2011003271
申请日：2011-05-02
申请人： AMOREPACIFIC CORP , KIM JI-HYUN
发明人： KIM JI-HYUN
IPC分类号： A45D44/22
CPC分类号： A45D44/002
摘要： The present invention relates to a roll mask pack. In detail, the mask pack, to be closely attached to the front surface of the face to achieve a skin-care effect, may be manufactured in a scroll shape to improve use convenience. Also, the mask pack may be individually packaged to minimize the use of packing material, thereby reducing production costs and the unit price. The roll mask pack of the present invention includes a mask pack (100) wound into a scroll shape, the mask pack having perforated lines (101) running across the length of a stencil paper at every predetermined unit of length such that the stencil paper can be cut therealong in the widthwise direction, a bobbin (300) provided as a double pipe and sealed together with an essence (200) by a seal cap (380), the bobbin (300) having a plurality of essence-injection holes (330) punched in the lengthwise direction such that the plurality of essence-injection holes (330) are temporarily opened by a slider (370) that is slidable in the left/right directions together with a pusher (350), thereby coating the essence (200) onto the mask pack (100), and a case (400) surrounding the bobbin (300). The mask pack (100) which has a long length and which is extracted through an extraction groove (310) of the bobbin (300) may be cut one by one along the perforated lines (101).
摘要翻译：本发明涉及一种卷帘包装盒。具体而言，可以制造紧密贴合在脸部的前表面以实现护肤效果的面具包，以提高使用的便利性。此外，面罩包可以单独包装以最小化包装材料的使用，从而降低生产成本和单价。本发明的卷帘包装盒包括卷绕成涡卷状的面膜包装（100），所述面膜包装件具有穿孔线（101），每隔预定长度的单位长度延伸穿过模版纸的长度，使得模版纸可以在宽度方向上被切割成线轴（300），其被设置为双管并且通过密封帽（380）与精华（200）一起密封，所述线轴（300）具有多个精华喷射孔（330）），使得多个精华喷射孔（330）通过与推动器（350）一起在左右方向上滑动的滑块（370）暂时打开，从而涂覆精华（200））到所述面罩包（100）上，以及围绕所述线轴（300）的壳体（400）。可以沿着穿孔线（101）一个接一个地切割具有长度并且通过线轴（300）的提取槽（310）提取的掩模组100。

9. 发明申请

WO2008111711A1 METHOD FOR MANUFACTURING DIAPHRAGM OF ACOUSTIC TRANSDUCER 审中-公开
标题翻译：声波传感器制造方法
公开(公告)号：WO2008111711A1
公开(公告)日：2008-09-18
申请号：PCT/KR2007/004000
申请日：2007-08-21
申请人： EM-TECH. CO., LTD. , HEO, Soon , LEE, Hyun-Seuk , KIM, JI-Hyun , CHOI, Jin-Soo , JEONG, Seung-Kiu
发明人： HEO, Soon , LEE, Hyun-Seuk , KIM, JI-Hyun , CHOI, Jin-Soo , JEONG, Seung-Kiu
IPC分类号： H04R7/00 , H04R7/02
CPC分类号： H04R31/003
摘要： The present invention discloses a method for manufacturing a diaphragm (120) of an acoustic transducer which can cut down a manufacturing cost by reducing waste of a film material, and which can prevent the diaphragm (120) from being eccentrically positioned in the acoustic transducer. The method for manufacturing the diaphragm of the acoustic transducer includes the steps of cutting a polymer film into a size insertable into a molding die, positioning the cut film in the molding die, heating the molding die and pressurizing the film at the same time, cooling the molding die and removing the pressure applied to the film, and separating the molded film from the molding die. An outer guide portion (G) bent in an upward or downward direction is formed at the outer portion of the molded film. The molding die for the manufacturing method can cut down the manufacturing cost by reducing waste of the film material.
摘要翻译：本发明公开了一种用于制造声换能器的振膜（120）的方法，该方法可以通过减少膜材料的浪费来降低制造成本，并且可以防止振膜（120）偏心放置在声换能器中。声学换能器的隔膜的制造方法包括以下步骤：将聚合物膜切割成可插入成型模具的尺寸，将切割膜定位在成型模具中，加热成型模具并同时对膜进行加热成型模具，并且去除施加到膜上的压力，并将模制膜与成型模具分离。在模制薄膜的外部形成有向上或向下弯曲的外导向部分（G）。用于制造方法的成型模具可以通过减少膜材料的浪费来降低制造成本。

10. 发明申请

WO2006062273A1 BRANCHED-AMINO ACID SUPPLEMENT FOOD 审中-公开
标题翻译：分支氨基酸补充食品
公开(公告)号：WO2006062273A1
公开(公告)日：2006-06-15
申请号：PCT/KR2005/000517
申请日：2005-02-25
申请人： KIM, Se-Gyu , KIM, Ji-Hyun
发明人： KIM, Se-Gyu , KIM, Ji-Hyun
IPC分类号： A23L1/305
CPC分类号： A23L33/175
摘要： The present invention relates to a health supplement food utilizing, in particular, branched amino acids from among essential amino acids. More specifically, the present invention relates to: a health supplement food comprising branched chain amino acids (hereinafter, referred to as LIV) composed of leucine (L), isoleucine (I) and valine (V) which is made to have a composition similar to essential amino acids contained in naturally-occurring milk, eggs, soybeans, beef and the like, and enhancing instant impact power under anaerobic conditions, via addition of L- glutamine and taurine which are essentially required when a person is exposed to excessive exercise, stress or overwork; a health supplement food for improving a weak constitution, comprising herbal materials such as ginseng, red ginseng and Acanthopanax; and a diet food or beverage further comprising dietary fibers such as inulin, polydextrose and crystalline cellulose, and carnitine and hydroxy citric acid.
摘要翻译：本发明涉及使用特别是必需氨基酸中的支链氨基酸的健康补充食品。更具体地，本发明涉及包含由亮氨酸（L），异亮氨酸（I）和缬氨酸（V）组成的支链氨基酸（以下称为LIV）的健康补充食品，其具有类似的组成天然存在的牛奶，鸡蛋，大豆，牛肉等中所含的必需氨基酸，以及通过加入L-谷氨酰胺和牛磺酸，在厌氧条件下增加即时冲击力，这在使用者过度运动时基本上是必需的，压力或过度劳累; 一种健康补充食品，用于改善薄弱的体质，包括人参，红参，刺五加等草本植物; 以及进一步包含膳食纤维如菊粉，聚右旋糖和结晶纤维素以及肉碱和羟基柠檬酸的饮食食品或饮料。

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