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1. 发明申请

WO2012027609A2 EXTRACTS FROM PIRIN+ AND PIRIN- PLANTS AND USES THEREOF 审中-公开
标题翻译：从皮林+和皮皮植物提取物及其用途
公开(公告)号：WO2012027609A2
公开(公告)日：2012-03-01
申请号：PCT/US2011/049220
申请日：2011-08-25
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , WARPEHA, Katherine , KAUFMAN, Lon
发明人： WARPEHA, Katherine , KAUFMAN, Lon
IPC分类号： C12N15/82 , A01H5/00 , C12N15/29 , C12P17/06
CPC分类号： C12N15/8257 , A61K8/97 , A61K31/353 , A61Q17/005 , C12N9/0069 , C12N15/8243 , C12N15/8271 , C12P17/06
摘要： The present disclosure provides methods of making and using plant extracts that include quercetin, which are generated from transgenic plants that have decreased pirin activity (prn-). Such transgenic plants and their extracts can be used to increase tolerance of a plant to a stressor, such as UV light, as well as treat tumor cells (such as kill cancer cells), prevent certain types of fungal infections (such as C. gattii ), and increase antioxidant activity. The present disclosure also provides methods of making and using plant extracts that are depleted of quercetin, which are generated from transgenic plants that have increased pirin activity (prn+). Such transgenic plants and their extracts can be used to prevent certain types of fungal infections (such as C. neoformans ). Also provided are compositions that include the prn- or prn+ extracts, such as a plastic coated with the extract.
摘要翻译：本公开提供了制备和使用植物提取物的方法，所述植物提取物包括由具有降低的pirin活性（prn-）的转基因植物产生的槲皮素。这样的转基因植物及其提取物可用于增加植物对诸如UV光的胁迫剂的耐受性，以及治疗肿瘤细胞（例如杀死癌细胞），防止某些类型的真菌感染（例如C.gattii ），并增加抗氧化活性。本公开还提供了制备和使用从具有增加的pirin活性（prn +）的转基因植物产生的槲皮素贫化的植物提取物的方法。这些转基因植物及其提取物可用于预防某些类型的真菌感染（如新型隐球菌）。还提供了包括prn或prn +提取物的组合物，例如涂覆有提取物的塑料。

2. 发明申请

WO2008106463A1 PHENYLALANINE FOR PLANT PROTECTION AGAINST UV RADIATION 审中-公开
标题翻译：苯乙烯胺用于防止紫外线辐射的植物保护
公开(公告)号：WO2008106463A1
公开(公告)日：2008-09-04
申请号：PCT/US2008/055036
申请日：2008-02-26
申请人： THE BOARD OF TRUSTEES OF THE UNIVERITY OF ILLINOIS , WARPEHA, Katherine , KAUFMAN, Lon, S.
发明人： WARPEHA, Katherine , KAUFMAN, Lon, S.
IPC分类号： C12N15/82 , A01N33/00
CPC分类号： A01H3/04 , A01N37/36 , A01N37/42 , A01N37/44 , A01N61/00 , C12N9/88 , C12N15/8251 , C12N15/8271
摘要： Compositions including phenylalanine, analogues, and phenylalanine precursors protect plants against environmental stressors. Delivery systems and methods of treating are provided.
摘要翻译：包括苯丙氨酸，类似物和苯丙氨酸前体的组合物可保护植物免受环境胁迫。提供给药系统和治疗方法。

3. 发明申请

WO2012027609A3 EXTRACTS FROM PIRIN+ AND PIRIN- PLANTS AND USES THEREOF 审中-公开
标题翻译：来自PIRIN +和PIRIN-植物的提取物及其用途
公开(公告)号：WO2012027609A3
公开(公告)日：2012-07-12
申请号：PCT/US2011049220
申请日：2011-08-25
申请人： UNIV ILLINOIS , WARPEHA KATHERINE , KAUFMAN LON
发明人： WARPEHA KATHERINE , KAUFMAN LON
IPC分类号： C12N15/82 , A01H5/00 , C12N15/29 , C12P17/06
CPC分类号： C12N15/8257 , A61K8/97 , A61K31/353 , A61Q17/005 , C12N9/0069 , C12N15/8243 , C12N15/8271 , C12P17/06
摘要： The present disclosure provides methods of making and using plant extracts that include quercetin, which are generated from transgenic plants that have decreased pirin activity (prn-). Such transgenic plants and their extracts can be used to increase tolerance of a plant to a stressor, such as UV light, as well as treat tumor cells (such as kill cancer cells), prevent certain types of fungal infections (such as C. gattii), and increase antioxidant activity. The present disclosure also provides methods of making and using plant extracts that are depleted of quercetin, which are generated from transgenic plants that have increased pirin activity (prn+). Such transgenic plants and their extracts can be used to prevent certain types of fungal infections (such as C. neoformans). Also provided are compositions that include the prn- or prn+ extracts, such as a plastic coated with the extract.
摘要翻译：本公开提供了制备和使用包含槲皮素的植物提取物的方法，所述槲皮素由具有降低的pirin活性（prn-）的转基因植物产生。这些转基因植物及其提取物可用于增加植物对胁迫因子如紫外线的耐受性，以及治疗肿瘤细胞（例如杀死癌细胞），预防某些类型的真菌感染（例如C.gattii ），并增加抗氧化活性。本公开内容还提供了制备和使用缺乏槲皮素的植物提取物的方法，所述植物提取物由增加了pirin活性的转基因植物（prn +）产生。这种转基因植物及其提取物可用于预防某些类型的真菌感染（如新生隐球菌）。还提供了包含prn-或prn +提取物的组合物，例如涂覆有提取物的塑料。

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