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1. 发明申请

WO2017218294A1 FLUIDIC CONNECTOR ASSEMBLY FOR QUICK CONNECT/ DISCONNECT 审中-公开
标题翻译：用于快速连接/断开的流体连接器组件
公开(公告)号：WO2017218294A1
公开(公告)日：2017-12-21
申请号：PCT/US2017/036590
申请日：2017-06-08
申请人： IDEX HEALTH & SCIENCE LLC
发明人： BEEMER, Eric , ELLIS, Scott , GRAHAM, Craig , NIENHUIS, Nathaniel , SANDERS, Troy
IPC分类号： F16L37/098 , A61M39/10 , F16L37/00 , F16L37/04 , F16L37/084 , F16L37/133
摘要： A fluidic connection assembly and methods for quickly connecting or disconnecting a tube to a port by hand and without the use of tools. A body is adapted to receive a tube therethrough, and may have at least two sides which are hinged. Each of the hinged sides has corresponding latching portions or projections located near a lower end of the body. These projections are adapted to fit into a port or other fitting and be securely held in place. The assembly may include a tube extending through a body and through a spring located between the end of the body and the end of the tube, whereby the spring exerts a force directly or indirectly against the end of the tube and against the body, thus holding the tubing securely and sealingly engaged in the port when the assembly is connected. The body may further comprise an additional body or an adapter, and/or a cap and latch. A second spring may be used to push a projecting member into a groove or notch of an adapter when an end of the adapter is inserted into one end of the latch or the body. The fluidic connection assembly is useful in analytical instrument systems, such as for in vitro applications and/or in high pressure applications, among other things, and may be used in methods for connecting, or disconnecting, tubing or a fluidic connection assembly from a port or other fitting or connection.
摘要翻译：一种流体连接组件和方法，用于手动和不使用工具快速连接或断开管到端口。主体适于接收穿过其中的管，并且可以具有至少两个铰接的侧面。每个铰接侧具有位于主体下端附近的对应的锁定部分或突起。这些突出部分适合装入一个端口或其他配件并牢固地固定。该组件可以包括延伸穿过主体并穿过位于主体的端部和管的端部之间的弹簧的管，由此弹簧直接或间接地施加力到管的端部并且抵靠主体，从而保持当连接组件时，管道牢固且密封地接合在端口中。主体可以进一步包括附加主体或适配器，和/或帽和闩锁。当适配器的一端插入到闩锁或本体的一端中时，第二弹簧可用于将突出构件推入适配器的凹槽或凹口中。流体连接组件在分析仪器系统中是有用的，例如用于体外应用和/或高压应用等，并且可用于将管道或流体连接组件与端口连接或断开连接的方法或其他配件或连接。

2. 发明申请

WO2017205876A9 METHODS AND APPARATUS FOR COATED FLOWCELLS 审中-公开
公开(公告)号：WO2017205876A9
公开(公告)日：2017-11-30
申请号：PCT/US2017/035044
申请日：2017-05-30
申请人： IDEX HEALTH & SCIENCE LLC
发明人： SIRKIS, Jim , GRAFTON, Meggie , EDLOU, Samad, M.
IPC分类号： B29C65/52 , B01L3/00 , B29C65/00 , B29C65/48
摘要： Microfluidic devises and process for making the devices include coating a substrate with an active oxygen layer and covalently bonding a polymeric microfluidic pattern to the substrate and devices made by the process.

3. 发明申请

WO2016112119A1 PULSE DAMPENER WITH AUTOMATIC PRESSURE-COMPENSATION 审中-公开
标题翻译：具有自动压力补偿的脉冲阻尼器
公开(公告)号：WO2016112119A1
公开(公告)日：2016-07-14
申请号：PCT/US2016/012359
申请日：2016-01-06
申请人： IDEX HEALTH & SCIENCE LLC
发明人： HARTMANN, Daniel, M. , TSIRLIS, Efthimios
IPC分类号： F16L55/04
CPC分类号： F16L55/041 , F16L55/043
摘要： A fluid pulse dampener with automatic pressure-compensation is provided. A system of chambers and channels in the dampener creates an internal feedback mechanism that increases or decreases a compensating pressure on the membrane in response to increases or decreases in the pressure of a fluid moving past the other side of the membrane. Variations of the pulse dampener allow for the input and / or output of gas flow to be restricted or increased as may be desired.
摘要翻译：提供了具有自动压力补偿的流体脉冲阻尼器。阻尼器中的腔室和通道的系统产生内部反馈机构，其响应于流过膜的另一侧的流体的压力的增加或减小而增加或减小膜上的补偿压力。脉冲阻尼器的变化允许根据需要限制或增加气流的输入和/或输出。

4. 发明申请

WO2015160840A1 HIGH PRESSURE FLUIDIC CONNECTION ASSEMBLIES 审中-公开
标题翻译：高压流体连接组件
公开(公告)号：WO2015160840A1
公开(公告)日：2015-10-22
申请号：PCT/US2015/025808
申请日：2015-04-14
申请人： IDEX HEALTH & SCIENCE LLC
发明人： GRAHAM, Craig , PEIN, Don
IPC分类号： F16L19/06
CPC分类号： F16L21/007 , B01D15/10 , F16L19/0206 , F16L19/0212 , F16L19/0243 , F16L33/224 , F16L2201/44 , G01N30/6004 , G01N30/6026 , G01N2030/027
摘要： Fluidic connection assemblies, ports, unions and other components are provided that are well-suited for use in HPLC and UHPLC, as well as in other analytical instrument systems. Such assemblies, ports, unions and components can be biocompatible. The present disclosure overcomes one or more of the deficiencies of the prior art by providing fluidic connection assemblies that are well-suited for use in Al and LC systems, and are particularly well-suited in some embodiments for use in high pressure and ultra-high pressure liquid chromatography systems, such as HPLC and UHPLC.
摘要翻译：提供流体连接组件，端口，联合体和其他组件，非常适合用于HPLC和UHPLC以及其他分析仪器系统。这样的组件，端口，联合和组件可以是生物兼容的。本公开通过提供非常适合用于Al和LC系统的流体连接组件来克服现有技术的一个或多个缺陷，并且在一些实施例中特别适用于高压和超高高压液相色谱系统，如HPLC和UHPLC。

5. 发明申请

WO2014160462A3 CONNECTOR WITH STRUCTURAL REINFORCEMENT AND BIOCOMPATIBLE FLUID PASSAGEWAY 审中-公开
标题翻译：结构加固连接器和生物易燃液体通道
公开(公告)号：WO2014160462A3
公开(公告)日：2015-01-15
申请号：PCT/US2014026713
申请日：2014-03-13
申请人： IDEX HEALTH & SCIENCE LLC , BEEMER ERIC
发明人： BEEMER ERIC
IPC分类号： B29C45/14 , F16L19/06 , F16L31/00
CPC分类号： B29C45/14819 , B01L3/563 , B01L2200/0689 , B01L2300/0838 , B01L2300/163 , B29C45/14344 , B29C45/14598 , B29C2045/1436 , F16L31/00 , F16L33/24 , F16L41/021 , G01N30/26 , G01N30/6026 , G01N30/6039 , G01N30/6043
摘要： A connector with a biocompatible fluid passageway and method for manufacturing thereof is described. The biocompatible connector may be used in an analytical instrument (AI) system as a union, an adapter, a tee, a cross, a manifold, a valve, a column filter retainer, or for other fittings or components. The connector has a reinforcement insert and a biocompatible molding covering portions of the reinforcement insert. The reinforcement insert has a first portion, a second portion, and a middle portion between the first portion and the second portion. The first and second portions have threaded sections and each have a plurality of non-threaded sections. For a given portion, the junction of the non-threaded sections forms a lip by which to prevent the molded material from flowing into the threaded sections. In certain embodiments, an interior web is used in the reinforcement insert to provide additional structural support.
摘要翻译：描述了具有生物相容性流体通道的连接器及其制造方法。生物相容性连接器可以用作分离仪器（AI）系统中的联合体，适配器，三通，十字，歧管，阀，柱过滤器保持器或用于其他配件或部件。连接器具有加强插入件和覆盖加强件插入件的部分的生物相容性模制件。加强插件具有第一部分，第二部分和在第一部分和第二部分之间的中间部分。第一和第二部分具有螺纹部分，并且每个具有多个非螺纹部分。对于给定的部分，非螺纹部分的接合处形成唇缘，以防止模制材料流入螺纹部分。在某些实施例中，在加强件插入件中使用内部纤维网以提供额外的结构支撑。

6. 发明申请

WO2014085417A1 MICROFLUIDIC INTERCONNECT 审中-公开
标题翻译：微流连接
公开(公告)号：WO2014085417A1
公开(公告)日：2014-06-05
申请号：PCT/US2013/071936
申请日：2013-11-26
申请人： IDEX HEALTH & SCIENCE LLC
发明人： GRAHAM, Craig
IPC分类号： G01N30/60
CPC分类号： F16L37/244 , B01L3/502715 , B01L3/563 , B01L2200/025 , B01L2200/027 , B01L2200/0631 , B01L2200/0689 , B01L2300/0832 , B01L2300/0851 , F16L15/08 , F16L19/0237 , F16L19/065 , F16L21/00 , G01N30/6026 , G01N30/6095 , G01N30/88 , Y10T29/49826
摘要： A microfluidic interconnect system and method for assembly thereof is described. The microfluidic interconnect has a port (400) and a seal (500), with the port having a reverse taper. The port has a first port end (410), a second port end (420), and an inner port surface (430) with a tapered portion. Each port end has an opening with a diameter, and in certain embodiments, the diameter (417) of the first port end is smaller than the diameter (427) of the second port end. The seal has a first end (510) and a second end (520), and each seal end has a rim and an opening with an inner diameter and an outer diameter. The seal also has an inner surface (530) and an outer surface (540), where in certain embodiments, each surface has a tapered portion. In certain embodiments, the inner diameter (517) of the first seal end is equal to or larger than the inner diameter (527) of the second seal end, the outer diameter of the first seal end (518) is equal to or smaller than the outer diameter of the second seal end (528), and the outer diameter of the second seal end is larger than the outer diameter of each port end. In certain embodiments, a tube (600) is slidably coupled to the inner surface of the seal, and the tube has an outer diameter (618) that is equal to or larger than the inner diameter of the second seal end.
摘要翻译：描述了一种微流控互连系统及其装配方法。微流体互连具有端口（400）和密封件（500），端口具有反向锥度。该端口具有第一端口端口（410），第二端口端部（420）和具有锥形部分的内部端口表面（430）。每个端口具有直径的开口，并且在某些实施例中，第一端口端部的直径（417）小于第二端口端部的直径（427）。密封件具有第一端（510）和第二端（520），并且每个密封端具有边缘和具有内径和外径的开口。密封件还具有内表面（530）和外表面（540），其中在某些实施例中，每个表面具有锥形部分。在某些实施例中，第一密封端的内径（517）等于或大于第二密封端的内径（527），第一密封端（518）的外径等于或小于第二密封端（528）的外径和第二密封端的外径大于每个端口的外径。在某些实施例中，管（600）可滑动地联接到密封件的内表面，并且管具有等于或大于第二密封端的内径的外径（618）。

7. 发明申请

WO2013040387A3 PERISTALTIC PUMP WITH MULTIPLE INDEPENDENT CHANNELS 审中-公开
标题翻译：具有多个独立通道的蠕动泵
公开(公告)号：WO2013040387A3
公开(公告)日：2013-06-27
申请号：PCT/US2012055475
申请日：2012-09-14
申请人： IDEX HEALTH & SCIENCE LLC , OZTURK GUNAY
发明人： OZTURK GUNAY
IPC分类号： A61M5/142
CPC分类号： A61M5/14232 , A61M5/14228 , F04B43/1253 , F04B43/1261 , F04B43/1292
摘要： A multi-channel peristaltic pump in which each channel can be operated independently of the others. A peristaltic pump includes a plurality of motors, each of which drives a rotor shaft which is independently rotatable around an axis and which rotates a roller head having a plurality of rollers. The rotor shafts are disposed in a concentric manner. The peristaltic pump further can include a control system allowing an operator to selectively determine the speed and direction of rotation of each of the roller heads of the pump.
摘要翻译：多通道蠕动泵，每个通道可以独立于其他通道运行。蠕动泵包括多个电动机，每个电动机驱动可绕轴独立旋转的转子轴并且使具有多个辊的辊头旋转。转子轴以同心方式布置。蠕动泵还可以包括控制系统，该控制系统允许操作者选择性地确定泵的每个辊头的旋转的速度和方向。

8. 发明申请

WO2021158515A1 FLUID IMMERSION CONTROL FOR INVERTED MICROSCOPY 审中-公开
公开(公告)号：WO2021158515A1
公开(公告)日：2021-08-12
申请号：PCT/US2021/016162
申请日：2021-02-02
申请人： IDEX HEALTH & SCIENCE LLC
发明人： RIDEOUT, Shane Alexander , BRAVO, Jaime Javier , SANDERS, Troy N.
IPC分类号： G02B21/33 , G02B21/00 , G02B21/02 , G02B21/24 , G02B21/26
摘要： A fluid immersion control system may use a common electrode along with a plurality of sensor electrodes at a planar surface associated with a distal end of an immersion microscope objective to monitor electrical resistance of a fluid as an indication of presence of a fluid layer having a meniscus greater than a diameter of an optical axis used for immersion microscopy. The fluid immersion control system may activate replenishment of the fluid when the resistance indicates that the diameter is not immersed in the fluid.

9. 发明申请

WO2016069770A3 AXIAL TRANSFER LINE SHELL SIDE DEGASSING 审中-公开
标题翻译：轴向传输线壳侧脱落
公开(公告)号：WO2016069770A3
公开(公告)日：2016-07-07
申请号：PCT/US2015057854
申请日：2015-10-28
申请人： IDEX HEALTH & SCIENCE LLC
发明人： LIU QUAN , GERNER YURI , SIMS CARL
IPC分类号： B01D19/00 , B01D69/04
CPC分类号： B01D19/0031 , B01D69/046
摘要： An elongated fluid degassing apparatus may be employed as a fluid transfer line for fluidly connecting components in a liquid system, while at the same time degassing, or preventing re-gassing of, the fluid. The fluid transfer line degassing apparatus forms a shell and tube degassing arrangement, wherein shell-side fluid flow is facilitated by one or more spacer elements that centrally position a semi-permeable separation membrane in the shell chamber. The degasser may include one or more tubular separation membranes that provide a gas-permeable, liquid-impermeable contact surface to effect the gas-liquid separation of the process fluid.
摘要翻译：细长的流体脱气装置可以用作流体输送管线，用于流体连接液体系统中的组分，同时除气或防止流体再次充气。流体输送管线脱气装置形成壳管排气装置，其中壳侧流体流动通过一个或多个间隔元件来促进，所述间隔元件将半渗透分离膜居中地定位在壳室中。脱气器可以包括一个或多个管状分离膜，其提供气体可渗透的液体不可渗透的接触表面以实现过程流体的气液分离。

10. 发明申请

WO2016094511A1 CARBON NANOTUBE COMPOSITE MEMBRANE 审中-公开
标题翻译：碳纳米管复合膜
公开(公告)号：WO2016094511A1
公开(公告)日：2016-06-16
申请号：PCT/US2015/064697
申请日：2015-12-09
申请人： IDEX HEALTH & SCIENCE, LLC
发明人： SIMS, Carl , LIU, Quan
IPC分类号： B01D67/00 , B01D69/12 , B01D69/02 , B01D71/02 , B01D71/06 , B01D53/22 , B82B3/00 , B82B1/00 , B82Y30/00
CPC分类号： B01D71/36 , B01D53/228 , B01D69/10 , B01D71/34 , B01D2256/22 , B82Y30/00
摘要： A composite membrane for separations includes a fabric with a non-woven array of intermingled carbon nanotubes, and a dopant incorporated with the fabric to form a non-porous, permeable composite. The composite membrane may be used to separate a target gas from a liquid by mounting the composite membrane in a housing chamber, and conditioning a permeate side of the chamber to establish a driving force for the target gas across the non-porous, permeable composite membrane.
摘要翻译：用于分离的复合膜包括具有混合碳纳米管的无纺布阵列的织物和掺入织物的掺杂剂以形成无孔，可渗透的复合材料。复合膜可以用于通过将复合膜安装在容纳室中来分离目标气体与液体，并且调节室的渗透侧以建立穿过无孔透气复合膜的目标气体的驱动力。

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