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1. 发明申请

WO2011010792A3 NOVEL STRAIN OF PAENIBACILLUS SP. HPL-002 FOR PRODUCING ALKALINE XYLANASE, NOVEL XYLANASE ENZYME ISOLATED THEREFROM, AND METHOD FOR PRODUCING SAME 审中-公开
标题翻译：新鲜的PAENIBACILLUS SP菌株用于生产碱性XYLANASE的HPL-002，其隔离的新型XYLANASE酶及其生产方法
公开(公告)号：WO2011010792A3
公开(公告)日：2011-04-21
申请号：PCT/KR2010003643
申请日：2010-06-07
申请人： KOREA RES INST CHEM TECH , HWANG IN TAEK , PARK NO JOONG , LIM HEE KYOUNG , SONG HA YOUNG , CHO SOO JIN
发明人： HWANG IN TAEK , PARK NO JOONG , LIM HEE KYOUNG , SONG HA YOUNG , CHO SOO JIN
IPC分类号： C12N1/20 , C12N9/24 , C12N15/56 , C12P21/00
CPC分类号： C12Y302/01091 , C12N9/248 , C12P19/02 , C12R1/01 , C12Y302/01008
摘要： The present invention relates to a novel strain of the Paenibacillus genus for producing alkaline xylanase, to a novel xylanase enzyme isolated therefrom, and to a method for producing same. The novel strain of Paenibacillus sp. HPL-002 and xylanase of the present invention decompose xylan, a main component of various types cellulosic biomass, and is thus usefully applicable to the development of biofuels and alternative fuels, special functional materials, biopolymers, food and feed, and the like.
摘要翻译：本发明涉及一种用于生产碱性木聚糖酶的Paenibacillus属的新菌株，分离自其中的新型木聚糖酶及其制备方法。新菌株Paenibacillus sp。本发明的HPL-002和木聚糖酶分解木聚糖，木聚糖是各种类型的纤维素生物质的主要成分，因此可用于开发生物燃料和替代燃料，特殊功能材料，生物聚合物，食品和饲料等。

2. 发明申请

WO1991013069A1 HERBICIDAL PYRIDINE DERIVATIVES AND THEIR SALTS OF 3-(AMINOOXOACETYL)-2-(2-IMIDAZOLIN-2-YL) 审中-公开
标题翻译：除草剂吡啶衍生物及其3-（氨基乙酰基）-2-（2-咪唑烷-2-基）
公开(公告)号：WO1991013069A1
公开(公告)日：1991-09-05
申请号：PCT/KR1991000005
申请日：1991-02-28
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY , KIM, Dae, Whang , CHANG, Hae, Sung , JEON, Dong, Ju , RYU, Jae, Wook , HWANG, In, Taek
发明人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
IPC分类号： C07D401/04
CPC分类号： C07D401/04 , A01N43/50 , A01N43/78 , C07D401/14 , C07D417/14
摘要： The present invention relates to a new 3-(aminooxoacetyl)-2-(2-imidazolin-2-yl)pyridine and their salts, having a herbicidal activity, which is described in the structure of general formula (I) wherein, R is C1 - C4 alkyl; R is C1 - C4 alkyl, C3 - C5 cycloalkyl or C1 - C4 alkyl optionally substituted with 1 - 4 fluorine; R is hydrogen, C1 - C3 alkyl, C1 - C3 alkyl optionally substituted with substituents contained in the following group I, C2 - C4 alkenyl or C2 - C4 alkynyl; R is the same as R ; or phenyl, benzyl, pyridyl, furanyl, thiophenyl, benzofuranyl, dihydrobenzofuranyl, benzothiophenyl, dihydrobenzothiophenyl, indolyl, indolinyl, optionally substituted with 0-3 same or different substituents selected from the substituents contained in group II; and when taken together, connecting R and R , a 3-7 membered ring may be formed, in which may contain 0-3 double bonds or 0-3 O, N, SOn (n=0-2); W is O or S; X is hydrogen, C1 - C4 alkyl, C1 - C4 alkoxy, C1 - C4 alkoxyalkyl, or halogen; Y, Z are each hydrogen, halogen, C1 - C6 alkyl, C1 - C6 alkoxy, C1 - C6 alkoxyalkyl, C1 - C6 alkylthio, phenoxy, C1 - C6 haloalkyl, C1 - C6 alkylamino, C1 - C6 alkylsulfonyl or phenyl optionally substituted with one C1 - C4 alkyl, C1 - C4 alkoxy or halogen; and when taken together, a 5-6 membered ring may be formed in which may contain O, N, S double bonds or -(CH2)n-(n=0-4); A is hydrogen or -COR (where R is hydrogen, methyl or CH2Cl); when A is hydrogen, tautomeric isomer may exist; group I contains hydroxy, alkoxy, haloalkoxy, cyano, -CO2R (where R is hydrogen, alkyl, alkenyl, or alkynyl), alkylthio, alkylsulfonyl, phenylthio, phenylsulfonyl, haloalkylthio, alkenoxy, alkoxy, -NR R (where R , R are each hydrogen, alkyl, alkenyl or alkynyl or R , R may form a ring), phenyl, or phenoxy; group II contains group I substituents, halogen, nitro, haloalkyl, alkoxyalkyl, alkyl, alkenyl, alkynyl, alkylthioalkyl, -COR (where R is hydrogen, alkyl or phenyl), -CO2R (where R is hydrogen or alkyl), -SO3R (where R is hydrogen or alkyl), -SO2NR R , -CONR R (R , R are the same as above), or ( alpha ) (where n, m are an integer of 1-3, D is a single bond or double bond, O2, S, SO2, NCH3).
摘要翻译：本发明涉及具有除草活性的新的3-（氨基乙酰基）-2-（2-咪唑啉-2-基）吡啶及其盐，其在通式（I）的结构中描述，其中R' 1>是C 1 -C 4烷基; R 2是C 1 -C 4烷基，C 3 -C 5环烷基或任选被1-4个氟取代的C 1 -C 4烷基; R 3是氢，C 1 -C 3烷基，任选被下列I中所含的取代基取代的C 1 -C 3烷基，C 2 -C 4烯基或C 2 -C 4炔基; R 4与R 3相同; 或苯基，苄基，吡啶基，呋喃基，噻吩基，苯并呋喃基，二氢苯并呋喃基，苯并噻吩基，二氢苯并噻吩基，吲哚基，二氢吲哚基，任选被0-3个相同或不同的选自二组中所含取代基的取代基取代; 并且当连接R 3和R 4时，可以形成3-7元环，其中可以含有0-3个双键或0-3O，N，SOn（n = 0-2 ）; W是O或S; X是氢，C 1 -C 4烷基，C 1 -C 4烷氧基，C 1 -C 4烷氧基烷基或卤素; Y，Z各自为氢，卤素，C1-C6烷基，C1-C6烷氧基，C1-C6烷氧基烷基，C1-C6烷硫基，苯氧基，C1-C6卤代烷基，C1-C6烷基氨基，C1-C6烷基磺酰基或任选被一个C 1 -C 4烷基，C 1 -C 4烷氧基或卤素; 并且当一起形成5-6元环时，其中可含有O，N，S双键或 - （CH 2）n - （n = 0-4）; A是氢或-COR 5（其中R 5是氢，甲基或CH 2 Cl）; 当A是氢时，可能存在互变异构体; 基团I包含羟基，烷氧基，卤代烷氧基，氰基，-CO 2 R 6（其中R 6是氢，烷基，烯基或炔基），烷硫基，烷基磺酰基，苯硫基，苯基磺酰基，卤代烷硫基，链烯氧基，烷氧基， 6 R 7（其中R 6，R 7各自为氢，烷基，烯基或炔基或R 6，R 7可以形成环），苯基或苯氧基; 组II包含I族取代基，卤素，硝基，卤代烷基，烷氧基烷基，烷基，烯基，炔基，烷硫基烷基，-COR 8（其中R 8是氢，烷基或苯基），-CO 2 R 9（其中R -SO 3 R 10（其中R 10是氢或烷基），-SO 2 NR 6 R 7，-CONR 6 R 7（R 6），R 7与上述相同）或（α）（其中n，m为1-3的整数，D为单键或双键，O 2，S，SO 2，NCH 3）。

3. 发明申请

WO2011028041A3 TD PROBE AND ITS USES 审中-公开
标题翻译： TD探针及其用途
公开(公告)号：WO2011028041A3
公开(公告)日：2011-09-15
申请号：PCT/KR2010005971
申请日：2010-09-02
申请人： SEEGENE INC , CHUN JONG YOON , HWANG IN TAEK , LEE SANG KIL
发明人： CHUN JONG YOON , HWANG IN TAEK , LEE SANG KIL
IPC分类号： C12Q1/68 , C07H21/00 , C12N15/11
CPC分类号： C07H21/00 , C12Q1/6823 , C12Q2565/1015 , C12Q2561/101 , C12Q2525/161
摘要： The present invention relates to a target discriminative probe (TD probe) and its uses or applications. The TD probe is hybridized with a target nucleic acid sequence through both of the 5'-second hybridization portion and the 3'-first hybridization portion. When the TD probe is hybridized with a non-target nucleic acid sequence, both the 5'-second hybridization portion and the separation portion are not hybridized with the non-target nucleic acid sequence such that both portions form a single strand due to its low Tm value. As such, the TD probe exhibits distinctly different hybridization patterns for each of the target and the non-target nucleic acid sequence, discriminating the target nucleic acid sequence from the non-target nucleic acid sequence with much higher specificity.
摘要翻译：本发明涉及目标区分性探针（TD探针）及其用途或应用。 TD探针通过5'-第二杂交部分和3'-第一杂交部分与靶核酸序列杂交。当TD探针与非靶核酸序列杂交时，5'-第二杂交部分和分离部分均不与非靶核酸序列杂交，使得两部分由于其低而形成单链 Tm值。如此，TD探针针对目标核酸序列和非目标核酸序列中的每一个表现出明显不同的杂交模式，以非常高的特异性将目标核酸序列与非目标核酸序列区分开来。

4. 发明申请

WO2011037306A1 DETECTION OF TARGET NUCLEIC ACID SEQUENCES BY CYCLIC EXONUCLEOLYTIC REACTIONS 审中-公开
标题翻译：通过循环外显子反应检测目标核酸序列
公开(公告)号：WO2011037306A1
公开(公告)日：2011-03-31
申请号：PCT/KR2010/002209
申请日：2010-04-09
申请人： SEEGENE, INC. , CHUN, Jong Yoon , HWANG, In Taek
发明人： CHUN, Jong Yoon , HWANG, In Taek
IPC分类号： C12Q1/68 , C12N15/11 , G01N33/52
CPC分类号： C12Q1/682 , C12Q2565/1025 , C12Q2521/319
摘要： The present invention relates to the detection of a target nucleic acid sequence by a cyclic exonucleolytic reaction. The present method enabling to generate singals by probe digestion with no help of primers and to amplify signals with no help of simultaneous target amplification reactions may enable to detect multiple target sequences without any problems accounted in the conventional real-time PCR methods such as false positive signals and difficulties in oligonucleotides (primer and probe) selection and reaction condition optimization.
摘要翻译：本发明涉及通过循环核酸内切酶反应检测靶核酸序列。通过探针消化而不用引物帮助产生信号并且无需同时扩增反应的扩增信号的本发明方法可以检测多个靶序列，而不存在常规实时PCR方法中所存在的任何问题，例如假阳性寡核苷酸（引物和探针）选择和反应条件优化的信号和困难。

5. 发明申请

WO2011028041A2 TD PROBE AND ITS USES 审中-公开
标题翻译： TD探针及其用途
公开(公告)号：WO2011028041A2
公开(公告)日：2011-03-10
申请号：PCT/KR2010/005971
申请日：2010-09-02
申请人： SEEGENE, INC. , CHUN, Jong Yoon , HWANG, In Taek , LEE, Sang Kil
发明人： CHUN, Jong Yoon , HWANG, In Taek , LEE, Sang Kil
IPC分类号： C12Q1/68 , C12N15/11 , C07H21/00
CPC分类号： C07H21/00 , C12Q1/6823 , C12Q2565/1015 , C12Q2561/101 , C12Q2525/161
摘要： The present invention relates to a target discriminative probe (TD probe) and its uses or applications. The TD probe is hybridized with a target nucleic acid sequence through both of the 5'-second hybridization portion and the 3'-first hybridization portion. When the TD probe is hybridized with a non-target nucleic acid sequence, both the 5'-second hybridization portion and the separation portion are not hybridized with the non-target nucleic acid sequence such that both portions form a single strand due to its low Tm value. As such, the TD probe exhibits distinctly different hybridization patterns for each of the target and the non-target nucleic acid sequence, discriminating the target nucleic acid sequence from the non-target nucleic acid sequence with much higher specificity.
摘要翻译：本发明涉及目标区分性探针（TD探针）及其用途或应用。 TD探针通过5'-第二杂交部分和3'-第一杂交部分与靶核酸序列杂交。当TD探针与非靶核酸序列杂交时，5'-第二杂交部分和分离部分均不与非靶核酸序列杂交，使得两部分由于其低而形成单链 Tm值。如此，TD探针显示出针对靶标和非靶标核酸序列中的每一个的明显不同的杂交模式，以非常高的特异性将靶核酸序列与非靶核酸序列区分开来。

6. 发明申请

WO2011027966A2 TD PROBE AND ITS USES 审中-公开
标题翻译： TD探索及其用途
公开(公告)号：WO2011027966A2
公开(公告)日：2011-03-10
申请号：PCT/KR2010004119
申请日：2010-06-24
申请人： SEEGENE INC , CHUN JONG YOON , HWANG IN TAEK , LEE SANG KIL
发明人： CHUN JONG YOON , HWANG IN TAEK , LEE SANG KIL
IPC分类号： C12N15/11 , C07H21/00 , C12Q1/68
CPC分类号： C07H21/00 , C12Q1/6823 , C12Q2565/1015 , C12Q2561/101 , C12Q2525/161
摘要： The present invention relates to a target discriminative probe (TD probe) and its uses or applications. The TD probe is hybridized with a target nucleic acid sequence through both of the 5'-second hybridization portion and the 3'-first hybridization portion. When the TD probe is hybridized with a non-target nucleic acid sequence, both the 5'-second hybridization portion and the separation portion are not hybridized with the non-target nucleic acid sequence such that both portions form a single strand due to its low Tm value. As such, the TD probe exhibits distinctly different hybridization patterns for each of the target and the non-target nucleic acid sequence, discriminating the target nucleic acid sequence from the non-target nucleic acid sequence with much higher specificity.
摘要翻译：本发明涉及目标鉴别探针（TD探针）及其用途或应用。 TD探针通过5'-第二杂交部分和3'-第一杂交部分与靶核酸序列杂交。当TD探针与非靶核酸序列杂交时，5'-第二杂交部分和分离部分都不与非靶核酸序列杂交，使得两部分由于其低部分形成单链 Tm值。因此，TD探针对靶和非靶核酸序列中的每一个显示明显不同的杂交模式，以非常高的特异性区分靶核酸序列与非靶核酸序列。

7. 发明申请

WO2004005500A1 NOVEL POLYPEPTIDE HAVING FUNCTION OF 7-KETO-8-AMINOPELARGONIC ACID SYNTHASE OF PLANT AND METHOD FOR INDUCING GROWTH INHIBITION AND LETHALITY BY SUPPRESSING EXPRESSION OF THE POLYPEPTIDE 审中-公开
标题翻译：具有植物7-酮乙酰氨基酸合成酶功能的新型多肽和通过抑制多肽的表达诱导生长抑制和诱导的方法
公开(公告)号：WO2004005500A1
公开(公告)日：2004-01-15
申请号：PCT/KR2003/001301
申请日：2003-07-02
申请人： GENOMINE INC. , KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY , LEE, Dong-Hee , HWANG, In-Taek , CHOI, Jung-Sup , MIN, Yong-Ki , KIM, Tae-Joon , KO, Jae-Heung , KIM, Tae-Hoon , PARK, Yu-Shin , CHO, Kwang-Yun , LEE, Seon-Woo
发明人： LEE, Dong-Hee , HWANG, In-Taek , CHOI, Jung-Sup , MIN, Yong-Ki , KIM, Tae-Joon , KO, Jae-Heung , KIM, Tae-Hoon , PARK, Yu-Shin , CHO, Kwang-Yun , LEE, Seon-Woo
IPC分类号： C12N9/10
CPC分类号： C12N9/1029 , C12N15/8261 , C12N15/8263 , C12N15/8274 , Y02A40/146
摘要： The invention relates to a novel polypeptide participating in biotin biosynthesis of plant, a polynucleotide encoding the said polypeptide, a method for inducing plant growth inhibition by suppressing the expression or function of the said polypeptide, resulting in inhibition of biotin biosynthesis, and a method for identifying herbicidal compounds that inhibit the expression or function of the said polypeptide. Biotin biosynthesis is an essential process for the growth of plants, however, the process is not present in both human and animals. Therefore, the compounds suppressing the expression or function of the novel polypeptide that relates to biotin biosynthesis can be effectively used as a new herbicide doing human and animals no harm.
摘要翻译：本发明涉及参与植物生物素生物合成的新型多肽，编码所述多肽的多核苷酸，通过抑制所述多肽的表达或功能诱导植物生长抑制的方法，导致生物素生物合成的抑制，以及用于鉴定抑制所述多肽表达或功能的除草化合物。生物素生物合成是植物生长的重要过程，然而，该过程不存在于人类和动物中。因此，抑制与生物素生物合成相关的新型多肽的表达或功能的化合物可以有效地用作新的除草剂，使人类和动物无害。

8. 发明申请

WO2011078441A1 TSG PRIMER TARGET DETECTION 审中-公开
标题翻译： TSG PRIMER目标检测
公开(公告)号：WO2011078441A1
公开(公告)日：2011-06-30
申请号：PCT/KR2010/001873
申请日：2010-03-26
申请人： SEEGENE, INC. , CHUN, Jong Yoon , HWANG, In Taek
发明人： CHUN, Jong Yoon , HWANG, In Taek
IPC分类号： C12Q1/68 , C12N15/11 , C07H21/00
CPC分类号： C12Q1/6816 , C12Q2565/107 , C12Q2565/1015 , C12Q2565/137
摘要： The present invention relates to the detection of a target nucleic acid sequence in a real-time manner using a target signal generating primer (TSG primer) having dual interactive labels. The present invention allows for both target amplification and signal amplification by introducing dual interactive labels into a primer used in PCR reactions, ensuring real-time target detection by PCR reactions without the use of complicated oligonucleotides. The present invention could be free from the troublesome matters and shortcomings associated with conventional real-time PCR methods. The present invention allows for successful real-time target detection by using only a labeled primer. Also, the present invention can obtain strong signals indicative of the presence of target nucleic acid sequences in both a liquid phase and solid phase.
摘要翻译：本发明涉及使用具有双重交互标签的目标信号产生引物（TSG引物）以实时方式检测靶核酸序列。本发明允许通过将双重交互标记引入PCR反应中使用的引物来进行靶扩增和信号扩增，确保通过PCR反应的实时目标检测而不使用复杂的寡核苷酸。本发明可以免于与常规实时PCR方法相关的麻烦的事项和缺点。本发明允许仅使用标记的引物成功实现目标检测。此外，本发明可以获得指示靶核酸序列在液相和固相中存在的强信号。

9. 发明申请

WO2010018948A3 NOVEL PAENIBACILLUS SP. HPL-001 STRAIN THAT PRODUCES XYLANASE, NOVEL XYLANASE ENZYME ISOLATED THEREFROM, AND METHOD FOR PRODUCING SAME 审中-公开
标题翻译：新款PAENIBACILLUS SP。生产XYLANASE，分离的新型XYLANASE酶的HPL-001菌株及其生产方法
公开(公告)号：WO2010018948A3
公开(公告)日：2010-07-01
申请号：PCT/KR2009004403
申请日：2009-08-06
申请人： KOREA RESERACH INST OF CHEMICA , HWANG IN TAEK , PARK NO JOONG , LIM HEE KYOUNG , SONG HA YOUNG , CHO SOO JIN , CHANG JONG SAN
发明人： HWANG IN TAEK , PARK NO JOONG , LIM HEE KYOUNG , SONG HA YOUNG , CHO SOO JIN , CHANG JONG SAN
IPC分类号： C12N1/20
CPC分类号： C12R1/07 , C12N1/20 , C12N1/22 , C12N9/2434 , C12N9/248 , C12R1/01 , C12Y302/01008
摘要： The present invention deals with a novel strain of the Paenibacillus genus and a novel xylanase enzyme isolated therefrom and a method for producing same; the novel Paenibacillus sp. HPL-001 strain and xylanase of the present invention can be effectively used in the development of biofuels and alternative feedstocks, special functional materials, biopolymers, etc., by lysing xylan, which is the main ingredient of various forms of cellulosic biomass.
摘要翻译：本发明涉及Paenibacillus属的新菌株和从其中分离的新型木聚糖酶及其生产方法。小牛Paenibacillus sp。本发明的HPL-001菌株和木聚糖酶可以通过裂解作为各种形式的纤维素生物质的主要成分的木聚糖来有效地用于开发生物燃料和替代原料，特殊功能材料，生物聚合物等。

10. 发明申请

WO1995013276A1 NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME 审中-公开
标题翻译：含有它们的新型噻吩磺酰胺衍生物和除草剂组合物
公开(公告)号：WO1995013276A1
公开(公告)日：1995-05-18
申请号：PCT/KR1994000161
申请日：1994-11-09
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY , KIM, Dae, Whang , YUN, Kyeong, Yeol , RYU, Jae, Wook , LEE, Yeon, Soo , KANG, Seung, Kyu , HWANG, In, Taek
发明人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
IPC分类号： C07D409/12
CPC分类号： C07D521/00 , A01N47/36 , C07D333/34
摘要： The present invention relates to a thiophenesulfonylurea derivative represented by general formula (I), the process for preparation thereof, and herbicide using it; and a salt thereof, in which T represents a group T1, T2, or T3 having general formula (a), wherein E represents a direct bond; R represents hydrogen or C1-4 acyl; R represents C1-6 alkyl substituted with 1 to 3 halogen atoms; R represents hydrogen, C1-3 alkyl, C1-3 haloalkyl, halogen, cyano, C1-3 alkoxy, C1-3 haloalkoxy, amino, methylamino, dimethylamino, or C1-2 alkyl substitued with C1-2 alkoxy, C1-2 haloalkoxy, thiol, methylthio, cyano or hydroxy; A represents a group selected from A1 to A4 having general formulae (b), and a herbicidal composition containing these derivatives.
摘要翻译：本发明涉及由通式（I）表示的噻吩磺酰基脲衍生物，其制备方法和使用它的除草剂; 和其盐，其中T表示具有通式（a）的基团T1，T2或T3，其中E表示直接键; R代表氢或C1-4酰基; R 1表示被1至3个卤素原子取代的C 1-6烷基; R 2表示氢，C 1-3烷基，C 1-3卤代烷基，卤素，氰基，C 1-3烷氧基，C 1-3卤代烷氧基，氨基，甲基氨基，二甲基氨基或被C 1-2烷氧基取代的C 1-2烷基，C 1 -2卤代烷氧基，硫醇，甲硫基，氰基或羟基; A表示选自具有通式（b）的A1至A4的基团和含有这些衍生物的除草组合物。

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