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1. 发明申请

WO2009059124A2 CYCLIC GASEOUS COMPRESSION/EXPANSION FOR HEIGHTENED OIL SANDS EXTRACTION 审中-公开
标题翻译：循环气体压缩/膨胀用于高效油提取
公开(公告)号：WO2009059124A2
公开(公告)日：2009-05-07
申请号：PCT/US2008/081979
申请日：2008-10-31
申请人： UNIVERSITY OF UTAH RESEARCH FOUNDATION , HONG, Andy , CHA, Zhixiong
发明人： HONG, Andy , CHA, Zhixiong
IPC分类号： C10B53/06
CPC分类号： C10G1/047
摘要： A method for extracting hydrocarbons from sands can include: providing sands containing a hydrocarbon; mixing the hydrocarbon sands with water; heating the water before, during, or after being mixed with the hydrocarbon sands; increasing the pressure within a closed vessel containing the heated hydrocarbon and water mixture in the presence of gas or by injecting with gas; releasing the pressure of the heated hydrocarbon and water mixture in the vessel so as to create microbubbles from the dissolved gas in the water mixture; and collecting the hydrocarbon from the water. Optionally, the process is substantially devoid of adding caustic agents to the hydrocarbon and water mixture.
摘要翻译：从砂中提取烃的方法可以包括：提供含有烃的砂; 将碳氢化合物砂与水混合; 在与烃砂混合之前，期间或之后加热水; 在气体存在或通过注入气体的情况下增加包含加热的烃和水混合物的密闭容器内的压力; 释放容器中加热的烃和水混合物的压力，以便从水混合物中溶解的气体中产生微泡; 并从水中收集烃。任选地，该方法基本上没有向烃和水混合物中加入苛性剂。

2. 发明申请

WO2005040391A1 COMPOSITIONS AND METHODS FOR DIFFERENTIATING STEM CELLS 审中-公开
标题翻译：用于分化干细胞的组合物和方法
公开(公告)号：WO2005040391A1
公开(公告)日：2005-05-06
申请号：PCT/AU2004/001469
申请日：2004-10-25
申请人： MURDOCH CHILDRENS RESEARCH INSTITUTE , CHOO, Kong-Hong, Andy , WONG, Lee, Hwa , SAFFERY, Richard, Eric
发明人： CHOO, Kong-Hong, Andy , WONG, Lee, Hwa , SAFFERY, Richard, Eric
IPC分类号： C12N15/90
CPC分类号： C12N15/90 , A61K48/00 , C12N15/85
摘要： The present invention relates generally to the field of tissue engineering and genetic manipulation of cells and to methods for generating tissue suitable for use in repair, replacement, rejuvenation or augmentation therapy. Even more particularly, the present invention contemplates a method for genetically manipulating a stem cell by introducing a nucleic acid molecule comprising a centromere or neocentromere into the stem cell or a parent of the stem cell, wherein the nucleic acid molecule conveys genetic information which is capable of introducing to or modifying a trait within the stem cell or progeny of the stem cell such as but not limited to modulating the level of stem cell proliferation, differentiation and/or self-renewal. The engineered stem cells are useful inter alia in tissue repair, replacement, rejuvenation and/or augmentation therapy. The engineered stem cells may also be re-programmed, for example, to direct the cells down a different cell lineage.
摘要翻译：本发明一般涉及细胞的组织工程和遗传操作领域以及用于产生适合用于修复，替代，恢复或增生治疗的组织的方法。甚至更具体地，本发明考虑了通过将包含着丝粒或新中性丝氨酸的核酸分子引入干细胞或干细胞的母体来遗传操作干细胞的方法，其中所述核酸分子传递能够产生的遗传信息在干细胞或干细胞的后代中引入或修饰性状，例如但不限于调节干细胞增殖，分化和/或自我更新的水平。工程干细胞尤其可用于组织修复，替代，恢复和/或增强治疗。工程干细胞也可以被重新编程，例如将细胞引导到不同的细胞谱系。

3. 发明申请

WO0250288A9 NEOCENTROMERE-BASED MINI-CHROMOSOMES OR ARTIFICIAL CHROMOSOMES 审中-公开
标题翻译：基于NEOCENTROMERE的微型色素或人造色素
公开(公告)号：WO0250288A9
公开(公告)日：2003-08-07
申请号：PCT/AU0101644
申请日：2001-12-20
申请人： MURDOCH CHILDRENS RES INST , CHOO KONG-HONG ANDY , WONG LEE HWA , SAFFERY RICHARD ERIC
发明人： CHOO KONG-HONG ANDY , WONG LEE HWA , SAFFERY RICHARD ERIC
IPC分类号： G01N33/53 , A61K31/7088 , A61K48/00 , C12N5/10 , C12N15/09 , C12N15/68 , C12N15/85 , C12Q1/68 , G01N33/566 , C12N15/64 , C12N15/79 , C12N15/81 , C12N15/82
CPC分类号： C12N15/68 , A61K48/00 , C12N15/85 , C12N2800/204 , C12N2800/30
摘要： The present invention is directed generally to a defined or isolated nucleic acid molecule encompassing a neocentreomere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic mini-chromosomes and artificial chromosomes including mammalian (e.g. human) and non-mammalian mini-chromosomes and artificial chromosomes. The present invention further provides a telomere-associated chromosome truncation (TACT) approach to develop mini-chromosomes, but is not limited to this approach. It is directed to any truncation approach that produces a neocentromere-containing mini-chromosome, or any transfection approach using cloned or pre-fabricated DNA that provides neocentromere function in the construction of artificial chromosome. Such mini-chromosomes and artificial chromosomes are useful in a range of genetic therapies.
摘要翻译：本发明一般涉及包含新中间体或其功能衍生物或其潜在的，合成的或杂交形式的限定或分离的核酸分子，其特别地用于开发一系列真核细小染色体和包括哺乳动物的人造染色体（例如人类）和非哺乳动物微型染色体和人造染色体。本发明还提供了端粒相关染色体截短（TACT）方法来开发微型染色体，但不限于此。它涉及产生含有新中心体的微型染色体的任何截短方法，或使用在人造染色体构建中提供新中心体功能的克隆或预先制备的DNA的任何转染方法。这种微型染色体和人造染色体可用于一系列遗传疗法。

4. 发明申请

WO2009059124A3 CYCLIC GASEOUS COMPRESSION/EXPANSION FOR HEIGHTENED OIL SANDS EXTRACTION 审中-公开
标题翻译：循环气体压缩/膨胀加固油砂提取
公开(公告)号：WO2009059124A3
公开(公告)日：2009-08-13
申请号：PCT/US2008081979
申请日：2008-10-31
申请人： UNIV UTAH RES FOUND , HONG ANDY , CHA ZHIXIONG
发明人： HONG ANDY , CHA ZHIXIONG
IPC分类号： C10B53/06
CPC分类号： C10G1/047
摘要： A method for extracting hydrocarbons from sands can include: providing sands containing a hydrocarbon; mixing the hydrocarbon sands with water; heating the water before, during, or after being mixed with the hydrocarbon sands; increasing the pressure within a closed vessel containing the heated hydrocarbon and water mixture in the presence of gas or by injecting with gas; releasing the pressure of the heated hydrocarbon and water mixture in the vessel so as to create microbubbles from the dissolved gas in the water mixture; and collecting the hydrocarbon from the water. Optionally, the process is substantially devoid of adding caustic agents to the hydrocarbon and water mixture.
摘要翻译：从砂中提取烃的方法可以包括：提供含有烃的砂; 将烃砂与水混合; 在与烃砂混合之前，之中或之后加热水; 在气体存在下或通过注入气体增加含有加热的烃和水混合物的密闭容器内的压力; 释放容器中加热的烃和水混合物的压力，以从水混合物中的溶解气体产生微泡; 并从水中收集碳氢化合物。任选地，该方法基本上没有向烃和水混合物中添加苛性剂。

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