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1. 发明申请

WO2011064333A1 ULTRASONIC MERGING OF PARTICLES IN MICROWELLS 审中-公开
标题翻译：超微粒子在微波炉中的超声波合成
公开(公告)号：WO2011064333A1
公开(公告)日：2011-06-03
申请号：PCT/EP2010/068313
申请日：2010-11-26
申请人： Jettec AB , MANNEBERG, Otto , WIKLUND, Martin , ÖNFELT, Björn , FRISK, Thomas , HERTZ, Hans M. , VANHERBERGHEN, Bruno
发明人： MANNEBERG, Otto , WIKLUND, Martin , ÖNFELT, Björn , FRISK, Thomas , HERTZ, Hans M. , VANHERBERGHEN, Bruno
IPC分类号： B01J19/00 , B01L3/00 , B06B1/02
CPC分类号： B01J19/0046 , B01J2219/00315 , B01J2219/00486 , B01L3/5085 , B01L2200/0647 , B01L2400/0436 , B01L2400/0439
摘要： The present invention relates to a method for simultaneously merging suspended particles and/or cells in a plurality of discrete microwells, each of said microwells having at least a bottom wall and lateral walls, wherein a multifrequency or broadband acoustic wave comprising at least two different frequencies is applied to an inner volume of each of said microwells, the frequencies of said acoustic wave being selected to generate a standing and/or stationary wave in said volume; a device for simultaneously merging suspended particles and/or cells in a plurality of discrete microwells, comprising: a substrate with a plurality of discrete microwells, each of said microwells having at least a bottom wall and lateral walls; and one or more acoustic transducer(s), configured for applying a multifrequency or broadband acoustic wave, comprising at least two different frequencies, to an inner volume of each of said microwells; and the use of an acoustic transducer emitting a multifrequency or broadband acoustic wave comprising at least two different frequencies for simultaneously merging suspended particles and/or cells in a plurality of microwells.
摘要翻译：本发明涉及一种用于在多个离散的微孔中同时合并悬浮颗粒和/或细胞的方法，每个所述微孔至少具有底壁和侧壁，其中包括至少两个不同频率的多频或宽带声波被施加到每个所述微孔的内部体积，所述声波的频率被选择为在所述体积中产生静止和/或静止波; 一种用于同时将多个离散微孔中的悬浮颗粒和/或细胞并入的装置，包括：具有多个离散微孔的基底，每个所述微孔至少具有底壁和侧壁; 以及一个或多个声学换能器，被配置为将包括至少两个不同频率的多频或宽带声波施加到每个所述微孔的内部体积; 以及使用发射包括至少两个不同频率的多频或宽带声波的声学换能器，以同时合并多个微孔中的悬浮颗粒和/或细胞。

2. 发明申请

WO2007133144A1 DEBRIS REDUCTION IN ELECTRON-IMPACT X-RAY SOURCES 审中-公开
标题翻译：电子冲击X射线源的减少损耗
公开(公告)号：WO2007133144A1
公开(公告)日：2007-11-22
申请号：PCT/SE2007/000448
申请日：2007-05-08
申请人： JETTEC AB , HERTZ, Hans, M. , OTENDAL, Mikael , TUOHIMAA, Tomi
发明人： HERTZ, Hans, M. , OTENDAL, Mikael , TUOHIMAA, Tomi
IPC分类号： H01J35/08 , H05G2/00
CPC分类号： H01J35/08 , G21K2207/005 , H01J2235/082 , H05G2/005
摘要： A method for generating x-ray radiation, comprising the steps of forming a target jet by urging a liquid substance under pressure through an outlet opening, the target jet propagating through an area of interaction; and directing at least one electron beam onto the target jet in the area of interaction such that the electron beam interacts with the target jet to generate x-ray radiation; wherein the full width at half maximum of the electron beam in the transverse direction of the target jet is about 50% or less of the target jet transverse dimension. A system for carrying out the method is also disclosed.
摘要翻译：一种用于产生x射线辐射的方法，包括以下步骤：通过在压力下通过出口开启液体物质形成目标射流，所述目标射流通过相互作用区域传播; 并且在相互作用的区域中将至少一个电子束引导到目标射流上，使得电子束与目标射流相互作用以产生x射线辐射; 其中电子束在目标射流的横向方向上的半个最大宽度为靶射流横向尺寸的约50％或更小。还公开了一种用于执行该方法的系统。

3. 发明申请

WO1997040650A1 METHOD AND APPARATUS FOR GENERATING X-RAY OR EUV RADIATION 审中-公开
标题翻译：用于产生X射线或EUV辐射的方法和装置
公开(公告)号：WO1997040650A1
公开(公告)日：1997-10-30
申请号：PCT/SE1997000697
申请日：1997-04-25
申请人： HERTZ, Hans, M. , MALMQVIST, Lars , RYMELL, Lars , BERGLUND, Magnus
IPC分类号： H05G02/00
CPC分类号： H05G2/003 , H05G2/008 , H05H1/00
摘要： A method for generating X- or EUV-radiation via laser plasma emission, in which at least one target (17) is generated in a chamber, and at least one pulsed laser beam (3) is focused on the target (17) in the chamber. The target is generated in the form of a jet (17) of a liquid, and the laser beam (3) is focused on a spatially continuous portion of the jet (17). An apparatus for generating X- or EUV-radiation via laser plasma emission according to the method comprises a means for generating at least one laser beam (3), a chamber, a means (10) for generating at least one target (17) in the chamber, and a means (13) for focusing the laser beam (3) on the target (17) in the chamber (8). The target-generating means (10) is adapted to generate a jet (17) of a liquid. The focusing means (13) is adapted to focus the laser beam (3) on a spatially continuous portion of the jet (17).
摘要翻译：一种用于通过激光等离子体发射产生X射线或EUV辐射的方法，其中在腔室中产生至少一个靶（17），并且至少一个脉冲激光束（3）聚焦在目标（17）上室。目标以液体的喷射（17）的形式产生，并且激光束（3）聚焦在射流（17）的空间连续部分上。根据该方法通过激光等离子体发射产生X射线或EUV辐射的装置包括用于产生至少一个激光束（3），腔室，用于产生至少一个靶（17）的装置（10）的装置，以及用于将激光束（3）聚焦在腔室（8）中的靶（17）上的装置（13）。目标产生装置（10）适于产生液体的射流（17）。聚焦装置（13）适于将激光束（3）聚焦在射流（17）的空间连续部分上。

4. 发明申请

WO2007006322A1 METHOD AND DEVICE FOR ACOUSTIC MANIPULATION OF PARTICLES, CELLS AND VIRUSES 审中-公开
标题翻译：用于声音控制颗粒，细胞和病毒的方法和装置
公开(公告)号：WO2007006322A1
公开(公告)日：2007-01-18
申请号：PCT/EP2005/007355
申请日：2005-07-07
申请人： FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. , LEMOR, Robert , GÜNTHER, Christian , FUHR, Günter , WIKLUND, Martin , HERTZ, Hans
发明人： LEMOR, Robert , GÜNTHER, Christian , FUHR, Günter , WIKLUND, Martin , HERTZ, Hans
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/502761 , B01L3/502776 , B01L2300/0645 , B01L2300/168 , B01L2400/0439 , C12M33/00
摘要： The present invention relates to a method and device for non-intrusively manipulating suspended particles and/or cells and/or viruses, which are supplied to a micro-chamber or to a micro-channel (46) of a substrate, said micro-chamber or micro-channel (46) having at least a bottom wall as well as lateral walls. At least one acoustic wave (41) is applied via at least one acoustic transducer (42, 44) from outside of said substrate to an inner volume of said microchamber or micro-channel (46), a frequency of said acoustic wave (41) being selected to generate a standing and/or stationary acoustic wave in said volume. In the present method and device the acoustic wave (41) is applied laterally to said volume. The present device and method allow an efficient coupling of energy into the channels as well as an improved control of standing and/or stationary acoustic wave fields along the channels. Furthermore the device and method allow for transmission optical microscopy to observe the manipulated particles in the channels during manipulation.
摘要翻译：本发明涉及一种用于非侵入式操纵悬浮颗粒和/或细胞和/或病毒的方法和装置，其被提供给微室或衬底的微通道（46），所述微室或至少具有底壁以及侧壁的微通道（46）。至少一个声波（41）经由至少一个声换能器（42,44）从所述衬底的外部施加到所述微室或微通道（46）的内部体积，所述声波（41）的频率被选择以在所述体积中产生站立和/或静止的声波。在本方法和装置中，声波（41）横向地施加到所述体积上。本装置和方法允许能量有效地耦合到通道中，以及改善沿着通道的驻波和/或静止声波场的控制。此外，装置和方法允许透射光学显微镜在操纵期间观察通道中的操纵颗粒。

5. 发明申请

WO2004010745A1 CAPILLARY TUBING 审中-公开
标题翻译：毛细管
公开(公告)号：WO2004010745A1
公开(公告)日：2004-01-29
申请号：PCT/SE2003/001225
申请日：2003-07-18
申请人： JETTEC AB , JOHANSSON, Göran , HERTZ, Hans , DE GROOT, Jaco
发明人： JOHANSSON, Göran , HERTZ, Hans , DE GROOT, Jaco
IPC分类号： H05G2/00
CPC分类号： H05G2/003 , H05G2/006
摘要： A method and arrangement for generating x-ray or EUV radiation are disclosed. Target material is supplied from a container for target material to a jet-forming orifice in an interaction chamber by means of a flexible capillary tubing of considerable length, wherein the orifice is an integral part of the capillary tubing. A jet formed by urging target material through the orifice is made to interact with a beam of energy, thus producing a radiating plasma emitting the desired electromagnetic radiation. The use of a flexible capillary tubing for supplying target material from a source of target material to an orifice, which is integrated with the tubing, within an interaction chamber, in order to form therein a jet of target material for interaction with an energy beam to generate x-ray of EUV radiation, is also disclosed.
摘要翻译：公开了一种用于产生x射线或EUV辐射的方法和装置。目标材料通过具有相当长度的柔性毛细管从目标材料的容器供应到相互作用室中的喷射形成孔，其中孔是毛细管的一个组成部分。通过将目标材料通过孔推动形成的射流被制成与能量束相互作用，从而产生发射所需电磁辐射的辐射等离子体。使用柔性毛细管来将目标材料从目标材料源提供给在相互作用室内与管相结合的孔口，以在其中形成用于与能量束相互作用的靶材料射流生成的X射线的EUV辐射，也被披露。

6. 发明申请

WO2010083854A1 X-RAY WINDOW 审中-公开
公开(公告)号：WO2010083854A1
公开(公告)日：2010-07-29
申请号：PCT/EP2009/000481
申请日：2009-01-26
申请人： EXCILLUM AB , HERTZ, Hans , HEMBERG, Oscar , TUOHIMAA, Tomi , OTENDAL, Mikael
发明人： HERTZ, Hans , HEMBERG, Oscar , TUOHIMAA, Tomi , OTENDAL, Mikael
IPC分类号： H05G2/00 , G21K1/02
CPC分类号： H01J35/18 , G21K1/02 , H01J2235/082
摘要： A self-cleaning X-ray window arrangement includes a primary X-ray- transparent window element, separating an ambient pressure region from an intermediate region, and a secondary X-ray-transparent window element, separating the intermediate region from a reduced pressure region. A contaminant is expected to deposit on a side of the secondary element facing the reduced pressure region. A heat source is adapted to heat a portion of the secondary window element for thereby evaporating contaminant. The secondary element shields the primary element from the reduced pressure region, in which contaminant is present, whereas the pressure-tight primary window element carries most of the differential pressure between the ambient pressure region and the reduced pressure region. Several features of the invention help to decrease the rate at which contaminant enters the intermediate region. By maintaining the pressure in the intermediate region close to the reduced pressure, the mechanical stress on the secondary window element can be limited as well as the exposure to harmful gases.
摘要翻译：自清洁X射线窗口装置包括：初级X射线透明窗口元件，将环境压力区域与中间区域分开;以及次X射线透明窗口元件，将中间区域与减压区域分离。预期污染物沉积在面向减压区域的次级元件的一侧上。热源适于加热次窗口元件的一部分，从而蒸发污染物。次要元件将主要元件从存在污染物的减压区域屏蔽，而压力密封的主窗口元件承载环境压力区域和减压区域之间的大部分差压。本发明的几个特征有助于降低污染物进入中间区域的速率。通过保持接近减压的中间区域的压力，可以限制次窗口元件上的机械应力以及暴露于有害气体。

7. 发明申请

WO2003096764A1 METHOD AND ARRANGEMENT FOR PRODUCING RADIATION 审中-公开
标题翻译：生产辐射的方法和装置
公开(公告)号：WO2003096764A1
公开(公告)日：2003-11-20
申请号：PCT/EP2003/004984
申请日：2003-05-13
申请人： JETTEC AB , BERGLUND, Magnus , HANSSON, Björn , HEMBERG, Oscar , HERTZ, Hans , RYMELL, Lars
发明人： BERGLUND, Magnus , HANSSON, Björn , HEMBERG, Oscar , HERTZ, Hans , RYMELL, Lars
IPC分类号： H05G2/00
CPC分类号： H05G2/003 , H05G2/008
摘要： A method of producing a radiating plasma with an increased flux stability and uniformity is disclosed. The method comprises the steps of (210) generating a primary target by urging a liquid under pressure through a nozzle; (220) directing an energy pre-pulse onto the primary target to generate a secondary target in the form of a gas or plasma cloud; (230) allowing the thus formed sec ondary target to expand for a predetermined period of time; and (240) directing a main energy pulse onto the secondary target when the predetermined period of time has elapsed in order to produce a plasma radiating X-ray or EW radiation. The pre-pulse has a beam waist size that is larger, in at least one dimension, than the corresponding dimension of the primary target.
摘要翻译：公开了一种产生具有增加的通量稳定性和均匀性的辐射等离子体的方法。该方法包括以下步骤：（210）通过在压力下迫使液体通过喷嘴产生主要目标; （220）将能量预脉冲引导到主要靶上以产生气体或等离子体云的形式的次要靶; （230），允许如此形成的第二目标扩展预定时间段; 以及（240）当经过预定时间段时，将主能脉冲引导到次目标上，以产生等离子体辐射X射线或EW辐射。预脉冲具有比主要目标的对应尺寸更大的至少一个维度的束腰尺寸。

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